Professor Fiona Oakley Dr Simon Cockell Dr Olivier Govaere Professor Ann Daly Professor Arun Sanyal et al. | An unbiased ranking of murine dietary models based on their proximity to human metabolic dysfunction-associated steatotic liver disease (MASLD) | 2024 |
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Professor Ann Daly Dr Olivier Govaere Dr Simon Cockell Professor Quentin Anstee
| Hepatic glucose production rises with the histological severity of metabolic dysfunction-associated steatohepatitis | 2024 |
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Dr Olivier Govaere Dr Simon Cockell Michalina Zatorska Kristy Wonders Professor Dina Tiniakos et al. | Pharmacogene expression during progression of metabolic dysfunction-associated steatotic liver disease: Studies on mRNA and protein levels and their relevance to drug treatment | 2024 |
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Professor Ann Daly
| PharmVar GeneFocus: CYP4F2 | 2024 |
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Professor Ann Daly
| Relevance of PNPLA3, TM6SF2, HSD17B13, and GCKR Variants to MASLD Severity in an Egyptian Population | 2024 |
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Professor Ann Daly
| Roadmap to DILI research in Europe. A proposal from COST action ProEuroDILINet | 2024 |
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Dr Olivier Govaere Dr Megan Hasoon Dr Simon Cockell Dr Dina Tiniakos Professor Ann Daly et al. | A proteo-transcriptomic map of non-alcoholic fatty liver disease signatures | 2023 |
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Professor Ann Daly
| Drug-induced liver injury due to nitrofurantoin: Similar clinical features, but different HLA risk alleles in an independent cohort | 2023 |
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Professor Ann Daly
| Genetics of drug-induced liver injury: Current knowledge and future prospects | 2023 |
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Dr Olivier Govaere Professor Ann Daly
| Identification of Reduced ERAP2 Expression and a Novel HLA Allele as Components of a Risk Score for Susceptibility to Liver Injury Due to Amoxicillin-Clavulanate | 2023 |
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Professor Ann Daly
| Relevance of Pharmacogenomics to the Safe Use of Antimicrobials | 2023 |
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Professor Ann Daly
| The Sixth European Society of Pharmacogenomics and Personalised Therapy Congress | 2023 |
|
Dr Rebecca Darlay Professor Heather Cordell Professor Quentin Anstee Professor Ann Daly
| A multiancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological validation | 2022 |
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Dr Wei-yu Lin Dr Sarah Fordham Dr Nicola Sunter Dr Claire Elstob Dr Yaobo Xu et al. | Author Correction: Genome-wide association study identifies susceptibility loci for acute myeloid leukemia (Nature Communications, (2021), 12, 1, (6233), 10.1038/s41467-021-26551-x) | 2022 |
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Dr Rebecca Darlay Professor Heather Cordell Professor Ann Daly Professor Chris Day Dr Steven Masson et al. | Corrigendum to: 'A genetic risk score and diabetes predict development of alcohol-related cirrhosis in drinkers' [J Hepatol 2022 (76) 275–282] (Journal of Hepatology (2022) 76(2) (275–282), (S0168827821021115), (10.1016/j.jhep.2021.10.005)) | 2022 |
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Professor Ann Daly
| Determination of Pleiotropic Effect of Warfarin in VKORC1 and CYP2C9 Genotypes in Patients With Heart Valve Replacement | 2022 |
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Professor Ann Daly
| Epigenetics in drug disposition & drug therapy: symposium report of the 24th North American meeting of the International Society for the Study of Xenobiotics (ISSX) | 2022 |
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Dr Katherine Johnson Dr Peter Leary Dr Olivier Govaere Dr Matthew Barter Sarah Charlton et al. | Increased serum miR-193a-5p during non-alcoholic fatty liver disease progression: Diagnostic and mechanistic relevance | 2022 |
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Dr Olivier Govaere Dr Rebecca Darlay Dr Julien Peltier Dr Jeremy Palmer Dr Massimo Younes et al. | Macrophage Scavenger Receptor 1 mediates lipid-induced inflammation in non-alcoholic fatty liver disease | 2022 |
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Dr Olivier Govaere Professor Ann Daly Professor Quentin Anstee
| Metabolic signatures across the full spectrum of nonalcoholic fatty liver disease | 2022 |
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Professor Ann Daly
| Pharmacogenetics of the cytochromes P450: Selected pharmacological and toxicological aspects | 2022 |
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Dr Olivier Govaere Professor Ann Daly Professor Quentin Anstee
| Quantitative modeling of human liver reveals dysregulation of glycosphingolipid pathways in nonalcoholic fatty liver disease | 2022 |
|
Professor Ann Daly
| Human Leukocyte Antigen B*14:01 and B*35:01 Are Associated With Trimethoprim-Sulfamethoxazole Induced Liver Injury | 2021 |
|
Nardeen Eldafashi Dr Rebecca Darlay Dr Ruchi Shukla Misti McCain Robyn Watson et al. | A pdcd1 role in the genetic predisposition to nafld-hcc? | 2021 |
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Professor Ann Daly
| Genetic risk factors in drug-induced liver injury due to isoniazid-containing anti-tuberculosis drug regimens | 2021 |
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Dr Rebecca Darlay Dr Steven Masson Professor Chris Day Professor Ann Daly Professor Heather Cordell et al. | Genome-wide association study and meta-analysis on alcohol-related liver cirrhosis identifies novel genetic risk factors | 2021 |
|
Dr Wei-Yu Lin Dr Sarah Fordham Dr Nicola Sunter Dr Claire Elstob Dr Yaobo Xu et al. | Genome-wide association study identifies susceptibility loci for acute myeloid leukemia | 2021 |
|
Dr Olivier Govaere Dr Dina Tiniakos Professor Pierre Bedossa Dr Simon Cockell Dr Massimo Younes et al. | NASH limits anti-tumor surveillance in immunotherapy-treated HCC | 2021 |
|
Dr Steven Masson Professor Ann Daly Professor Heather Cordell Professor Chris Day
| Obesity, Diabetes, Coffee, Tea, and Cannabis Use Alter Risk for Alcohol-Related Cirrhosis in 2 Large Cohorts of High-Risk Drinkers | 2021 |
|
Professor Ann Daly Dr Olivier Govaere Professor Quentin Anstee
| Peptide-Based Urinary Monitoring of Fibrotic Non-Alcoholic Steatohepatitis by Mass Barcoded Activity-Based Sensors | 2021 |
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Professor Ann Daly
| Pharmacogenomics spotlight commentary: From the United Kingdom to global populations | 2021 |
|
Professor Quentin Anstee Priyadarshini Basu Dr Pallav Bhatnagar Professor Ann Daly
| rs641738C>T near MBOAT7 is associated with liver fat, ALT and fibrosis in NAFLD: A meta-analysis | 2021 |
|
Dr Olivier Govaere Dr Simon Cockell Professor Ann Daly Professor Quentin Anstee
| Transcriptomics Identify Thrombospondin-2 as a Biomarker for Nonalcoholic Steatohepatitis and Advanced Liver Fibrosis | 2021 |
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Professor Quentin Anstee Dr Rebecca Darlay Dr Simon Cockell Dr Olivier Govaere Dr Dina Tiniakos et al. | Genome-Wide Association Study of Non-Alcoholic Fatty Liver and Steatohepatitis in a Histologically-Characterised Cohort | 2020 |
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Professor Ann Daly
| HLA associations with infliximab-induced liver injury | 2020 |
|
Mohammad Alshabeeb Professor Ann Daly
| Investigation of Oxidative Stress-Related Candidate Genes as Risk Factors for Drug-Induced Liver Injury due to Co-Amoxiclav | 2020 |
|
Professor Ann Daly
| Polygenic architecture informs potential vulnerability to drug-induced liver injury | 2020 |
|
Dr Olivier Govaere Dr Simon Cockell Dr Dina Tiniakos Dr Rachel Queen Dr Massimo Younes et al. | Transcriptomic profiling across the nonalcoholic fatty liver disease spectrum reveals gene signatures for steatohepatitis and fibrosis | 2020 |
|
Professor Ann Daly
| A Missense Variant in PTPN22 is a Risk Factor for Drug-induced Liver Injury | 2019 |
|
Dr Tom Chamberlain Dr Sally Coulthard Mohammad Alshabeeb Professor Ann Daly
| Drug‐Induced Liver Injury due to Flucloxacillin: Relevance of Multiple Human Leukocyte Antigen Alleles | 2019 |
|
Wi Phatvej Dr Harish Datta Dr Simon Wilkinson Dr Elaine Mutch Professor Ann Daly et al. | Endocytosis and lack of cytotoxicity of alkyl–capped silicon quantum dots prepared from porous silicon | 2019 |
|
Professor Ann Daly
| Next-Generation Sequencing of PTGS Genes Reveals an Increased Frequency of Non-synonymous Variants among Patients with NSAID-Induced Liver Injury | 2019 |
|
Professor Ann Daly
| Shared Genetic Risk Factors Across Carbamazepine‐Induced Hypersensitivity Reactions | 2019 |
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Dr Steven Masson Professor Ann Daly Professor Heather Cordell Professor Chris Day
| Evaluation of laboratory tests for cirrhosis and for alcohol use, in the context of alcoholic cirrhosis | 2018 |
|
Sal Bakar Dr Peter Avery Dr Colin Brown Professor Ann Daly Professor Farhad Kamali et al. | Genetic and Clinical Factors Are Associated With Statin-Related Myotoxicity of Moderate Severity: A Case–Control Study | 2018 |
|
Professor Ann Daly
| HLA-A∗33:03-Restricted Activation of Ticlopidine-Specific T-Cells from Human Donors | 2018 |
|
Professor Ann Daly
| Human leukocyte antigen (HLA) and other genetic risk factors in drug-induced liver injury (DILI) | 2018 |
|
Professor Ann Daly
| Paracetamol metabolism, hepatotoxicity, biomarkers and therapeutic interventions: A perspective | 2018 |
|
Professor Ann Daly
| Pharmacogenetics of Adverse Drug Reactions | 2018 |
|
Professor Ann Daly
| Pharmacogenomics of CYP2C9: Functional and Clinical Considerations | 2018 |
|
Professor Ann Daly
| Are Polymorphisms in Genes Relevant to Drug Disposition Predictors of Susceptibility to Drug-Induced Liver Injury | 2017 |
|
Dr Sally Coulthard Professor Chris Day Professor Ann Daly
| Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study | 2017 |
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Professor Ann Daly
| Defining drug response for stratified medicine | 2017 |
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Professor Ann Daly
| Drug-Induced cholestasis: Mechanisms and importance | 2017 |
|
Professor Ann Daly
| Drug-Induced Liver Disease | 2017 |
|
Professor Ann Daly
| Minocycline hepatotoxicity: Clinical characterization and identification of HLA-B∗35:02 as a risk factor | 2017 |
|
Professor Ann Daly
| Pharmacogenetics: A general review on progress to date | 2017 |
|
Dr Lucy Walker Professor Ann Daly Dr Luca Miele Professor Quentin Anstee Professor Helen Reeves et al. | Telomerase reverse transcriptase germline mutations and hepatocellular carcinoma in patients with nonalcoholic fatty liver disease | 2017 |
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Professor Quentin Anstee Dr Yang-Lin Liu Dr Rebecca Darlay Professor Heather Cordell Professor Ann Daly et al. | Transcriptional regulation of PNPLA3 and its impact on susceptibility to nonalcoholic fatty liver Disease (NAFLD) in humans | 2017 |
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Professor Ann Daly Professor Farhad Kamali
| A multi-factorial analysis of response to warfarin in a UK prospective cohort | 2016 |
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Dr Sally Coulthard Professor Ann Daly
| HLA-DRB1*16:01-DQB1*05:02 is a novel genetic risk factor for flupirtine-induced liver injury | 2016 |
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Dr Sally Coulthard Professor Ann Daly
| Pharmacogenetic allele nomenclature: International workgroup recommendations for test result reporting | 2016 |
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Professor Ann Daly
| The Effect of the CYP1A1*2A Allele on Colorectal Cancer Susceptibility in a British Population | 2016 |
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Professor Ann Daly Professor Chris Day
| Variants in the LGALS9 Gene Are Associated With Development of Liver Disease in Heavy Consumers of Alcohol | 2016 |
|
Dr Sarah Steven Dr Kieren Hollingsworth Dr Benjamin Aribisala Dr Ahmad Al-Mrabeh Professor Ann Daly et al. | Weight Loss Decreases Excess Pancreatic Triacylglycerol Specifically in Type 2 Diabetes | 2016 |
|
Professor Chris Day Dr Steven Masson Professor Ann Daly Professor Heather Cordell
| Brief Report: Genetics of Alcoholic Cirrhosis-GenomALC Multinational Study | 2015 |
|
Professor Ann Daly
| Characterization of amoxicillin- and clavulanic acid-specific T cells in patients with amoxicillin-clavulanate-induced liver injury | 2015 |
|
Professor Ann Daly
| Comparison of dosing algorithms for acenocoumarol and phenprocoumon using clinical factors with the standard care in the Netherlands | 2015 |
|
Professor Quentin Anstee Professor Ann Daly Professor Chris Day
| Genetics of Alcoholic Liver Disease | 2015 |
|
Dr Peter Donaldson Professor Ann Daly Dr Luca Ermini Professor Debra Bevitt
| Genetics of Complex Disease | 2015 |
|
Professor Ann Daly
| Genome-wide investigation identifies common SNPs on Chr9p22.2 as risk factors for liver injury due to sulfa-methoxazole/trimethoprim | 2015 |
|
Professor Ann Daly
| HLA-A*33:01 is strongly associated with drug-induced liver injury (DILI) due to terbinafine and several other unrelated compounds | 2015 |
|
Dr Jeremy Palmer Dr Yang-Lin Liu Professor Chris Day Professor Ann Daly Professor Quentin Anstee et al. | Mechanistic Study of TM6SF2 in NAFLD pathogenesis: Stably transfected Huh7 cells over-expressing the TM6SF2 E167K variant exhibit greater levels of oxidative stress | 2015 |
|
Professor Ann Daly
| Minocycline hepatotoxicity: Clinical characterization and identification of HLA- B*35:02 as a risk factor | 2015 |
|
Professor Farhad Kamali Professor Ann Daly
| Oral anticoagulation: a critique of recent advances and controversies | 2015 |
|
Professor Ann Daly
| Pharmacogenetics of drug metabolizing enzymes in the United Kingdom population: Review of current knowledge and comparison with selected European populations | 2015 |
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Professor Ann Daly Professor Chris Day
| PNPLA3 Gene Polymorphism Is Associated With Predisposition to and Severity of Alcoholic Liver Disease | 2015 |
|
Professor Ann Daly
| Polymorphic Variants of Cytochrome P450: Relevance to Cancer and Other Diseases | 2015 |
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Professor Ann Daly
| Promiscuous T-cell responses to drugs and drug-haptens | 2015 |
|
Professor Farhad Kamali Professor Ann Daly
| Quality of life in patients with venous thromboembolism and atrial fibrillation treated with coumarin anticoagulants | 2015 |
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Dr Harsh Sheth Dr Michael Jackson Dr John Tyson Professor Ann Daly Professor Sir John Burn et al. | Relevance of genetic factors to warfarin dosing in India | 2015 |
|
Rodolphe Anty Professor Chris Day Professor Ann Daly Anh Tran Professor Quentin Anstee et al. | The FNDC5 rs3480 is protective on the steatosis and fibrosis in patients with NAFLD | 2015 |
|
Professor Ann Daly Professor Chris Day Dr Yang-Lin Liu Professor Quentin Anstee
| TM6SF2 as a Genetic Risk Factor for Fibrosis | 2015 |
|
Dr Yang-Lin Liu Professor Ann Daly Professor Chris Day Professor Quentin Anstee
| TM6SF2: Catch-22 in the Fight Against Nonalcoholic Fatty Liver Disease and Cardiovascular Disease? | 2015 |
|
Ching Ng Dr Abul Hasnat Professor Chris Day Professor Ann Daly
| N-acetyltransferase 2 (NAT2) genotype as a risk factor for development of drug-induced liver injury relating to antituberculosis drug treatment in a mixed-ethnicity patient group | 2014 |
|
Dr Yang-Lin Liu Dr Gillian Patman Julian Leathart Professor Alastair Burt Professor Chris Day et al. | Carriage of the PNPLA3 rs738409 C>G Polymorphism Confers an Increased Risk of Non-Alcoholic Fatty Liver Disease Associated Hepatocellular Carcinoma | 2014 |
|
Julian Leathart Professor Ann Daly Professor Chris Day Professor Quentin Anstee
| Gene Polymorphisms of Cellular Senescence Marker P21 and Disease Progression in Non-Alcohol-Related Fatty Liver Disease | 2014 |
|
Professor Ann Daly
| Genetic Basis of Drug-Induced Liver Injury: Present and Future | 2014 |
|
Professor Ann Daly
| Human Leukocyte Antigen (HLA) Pharmacogenomic Tests: Potential and Pitfalls | 2014 |
|
Professor Ann Daly
| Is There a Need to Teach Pharmacogenetics? | 2014 |
|
Professor Ann Daly
| Opportunities and limitations: the value of pharmacogenetics in clinical practice | 2014 |
|
Professor Ann Daly Professor Farhad Kamali
| Patients Benefit From Genetics-Guided Coumarin Anticoagulant Therapy | 2014 |
|
Professor Ann Daly
| Pharmacogenetic-guided dosing of coumarin anticoagulants: algorithms for warfarin, acenocoumarol and phenprocoumon | 2014 |
|
Professor Ann Daly
| Pharmacogenomics of Warfarin | 2014 |
|
Dr Harsh Sheth Dr Matthew Jackson Dr John Tyson Professor Ann Daly Dr Jonathan O'Halloran et al. | Point of care testing for improving risk- benefit ratio of aspirin and warfarin | 2014 |
|
Dr Yang-Lin Liu Professor Helen Reeves Professor Alastair Burt Dr Dina Tiniakos Professor Stuart McPherson et al. | TM6SF2 rs58542926 Influences Hepatic Fibrosis Progression in Patients with Non-Alcoholic Fatty Liver Disease | 2014 |
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Professor Quentin Anstee Dr Rebecca Darlay Julian Leathart Yilei Liu Professor Alastair Burt et al. | A candidate-gene approach to validation of genetic modifier associations using a large cohort with histologically characterised non-alcoholic fatty liver disease | 2013 |
|
Dr Patrick Kesteven Professor Ann Daly Dr Peter Avery Professor Farhad Kamali
| A Randomized Trial Comparing Genotype-Guided Dosing of Warfarin to Standard Dosing: The EU Pharmacogenetics of Anticoagulant Therapy (EU-PACT) Warfarin Study | 2013 |
|
Dr Patrick Kesteven Julian Leathart Professor Ann Daly Professor Farhad Kamali
| A Randomized Trial of Genotype-Guided Dosing of Warfarin | 2013 |
|
Professor Gareth Veal Julie Errington Sophie Rowbotham Nicola Illingworth Dr Ghada Malik et al. | Adaptive dosing approaches to the individualization of 13-cis-retinoic acid (isotretinoin) treatment for children with high-risk neuroblastoma | 2013 |
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Dr Yang-Lin LIU Dr Gillian Patman Julian Leathart Professor Alastair Burt Professor Chris Day et al. | Carriage of PNPLA3 I148M is Associated with an Increased Risk of Non-Alcoholic Fatty Liver Disease Associated Hepatocellular Carcinoma | 2013 |
|
Dr Ahmed Elsharkawy Dr Ulrich Schwab Dr Brendan McCarron Professor Alastair Burt Professor Ann Daly et al. | Efavirenz induced acute liver failure requiring liver transplantation in a slow drug metaboliser | 2013 |
|
Professor Ann Daly Professor Chris Day
| Genetic Polymorphisms of Galectin-9 (Gal-9) Associated with Risk of Developing Alcoholic Liver Disease (ALD) in Humans | 2013 |
|
Professor Ann Daly
| Human Leukocyte Antigen (HLA)-B(star)57:01-Restricted Activation of Drug-Specific T Cells Provides the Immunological Basis for Flucloxacillin-Induced Liver Injury | 2013 |
|
Professor Ann Daly
| Lung cancer risk in relation to nicotinic acetylcholine receptor, CYP2A6 and CYP1A1 genotypes in the Bangladeshi population | 2013 |
|
Professor Quentin Anstee Dr Yang-Lin Liu Professor Heather Cordell Dr Rebecca Darlay Professor Chris Day et al. | Mapping Expression Quantitative Traits Loci (EQTL) for PNPLA3 Gene Identifies Additional SNPs Associated with Non-Alcoholic Fatty Liver Disease (NAFLD) Independent of rs738409 | 2013 |
|
Professor Ann Daly
| Optimal dosing of warfarin and other coumarin anticoagulants: the role of genetic polymorphisms | 2013 |
|
Professor Ann Daly
| Pharmacogenomics of adverse drug reactions | 2013 |
|
Professor Ann Daly
| Relevance of CYP2E1 to non-alcoholic fatty liver disease | 2013 |
|
Professor Ann Daly Professor Farhad Kamali
| Cost-effectiveness of pharmacogenetics in anticoagulation: international differences in healthcare systems and costs | 2012 |
|
Professor Ann Daly
| CYP2D6 update: revised nomenclature for CYP2D7/2D6 hybrid genes | 2012 |
|
Professor Ann Daly Professor Chris Day
| Genetic association studies in drug-induced liver injury | 2012 |
|
Professor Ann Daly
| Genetic polymorphisms affecting drug metabolism: recent advances and clinical aspects | 2012 |
|
Professor Quentin Anstee Dr Rebecca Darlay Julian Leathart Professor Helen Reeves Professor Alastair Burt et al. | Genome-Wide Association Analysis Confirms Importance of PNPLA3 and Identifies Novel Variants Associated With Histologically Progressive Steatohepatitis in NAFLD | 2012 |
|
Professor Ann Daly
| Limited contribution of common genetic variants to risk for liver injury due to a variety of drugs | 2012 |
|
Professor Ann Daly Professor Gareth Veal Dr David Jamieson Dr Sally Coulthard
| Pharmacogenomics research at Newcastle University | 2012 |
|
Ahmad Alserri Professor Quentin Anstee Julian Leathart Julia Patch Professor Chris Day et al. | The SOD2 C47T polymorphism influences NAFLD fibrosis severity: Evidence from case-control and intra-familial allele association studies | 2012 |
|
Dr Ellen Hatch Dr Iain Matthews Professor Ann Daly Professor Farhad Kamali
| The population pharmacokinetics of R- and S-warfarin: effect of genetic and clinical factors | 2012 |
|
Professor Ann Daly
| Using genome-wide association studies to identify genes important in serious adverse drug reactions | 2012 |
|
Dr Tina Biss Dr Peter Avery Julian Leathart Dr John Hanley Professor Ann Daly et al. | VKORC1 and CYP2C9 genotype and patient characteristics explain a large proportion of the variability in warfarin dose requirement among children | 2011 |
|
Professor Ann Daly Professor Chris Day
| A common polymorphism in the ABCB11 gene is associated with advanced fibrosis in hepatitis C but not in non-alcoholic fatty liver disease | 2011 |
|
Professor Ann Daly
| Beyond DME: Genetic determinants of drug-induced liver toxicity | 2011 |
|
Professor Ann Daly
| Case Definition and Phenotype Standardization in Drug-Induced Liver Injury | 2011 |
|
Professor Alan Boddy Professor Ann Daly Professor Gareth Veal
| Characterisation of the metabolism of fenretinide by human liver microsomes, cytochrome P450 enzymes and UDP-glucuronosyltransferases | 2011 |
|
Dr Shyamal Wahie Professor Ann Daly Professor Heather Cordell Dr Andrew Carmichael Dr Mary Carr et al. | Clinical and Pharmacogenetic Influences on Response to Hydroxychloroquine in Discoid Lupus Erythematosus: A Retrospective Cohort Study | 2011 |
|
Dr Gul Ozhan Rajiv Lochan Jayadeva Julian Leathart Richard Charnley Professor Ann Daly et al. | Cyclooxygenase-2 polymorphisms and pancreatic cancer susceptibility | 2011 |
|
Rajiv Lochan Jayadeva Professor Ann Daly Professor Helen Reeves Richard Charnley
| Family history of cancer and tobacco exposure in index cases of pancreatic ductal adenocarcinoma | 2011 |
|
Professor Ann Daly Dr Stefano Ballestri Professor Chris Day
| Genetic determinants of susceptibility and severity in nonalcoholic fatty liver disease | 2011 |
|
Professor Quentin Anstee Professor Ann Daly Professor Chris Day
| Genetic modifiers of non-alcoholic fatty liver disease progression | 2011 |
|
Professor Quentin Anstee Professor Ann Daly Professor Chris Day
| Genetics of alcoholic liver disease and nonalcoholic fatty liver disease | 2011 |
|
Professor Ann Daly Dr Abul Hasnat
| Genotypes and phenotypes of CYP3A in Bangladeshi population | 2011 |
|
Julian Leathart Professor Ann Daly
| Genotyping for CYP2C9 and VKORC1 alleles by a novel point of care assay with HyBeacon(R) probes | 2011 |
|
Dr Stefano Ballestri Professor Chris Day Professor Ann Daly
| Polymorphism in the Farnesyl Diphosphate Farnesyl Transferase 1 Gene and Nonalcoholic Fatty Liver Disease Severity | 2011 |
|
Professor Ann Daly
| Practical recommendations for pharmacogenomics-based prescription: 2010 ESF-UB Conference on Pharmacogenetics and Pharmacogenomics | 2011 |
|
Professor Chris Day Dr Peter Donaldson Professor Ann Daly
| Susceptibility to amoxicillin-clavulanate-induced liver injury is influenced by multiple HLA class I and class II alleles | 2011 |
|
Rajiv Lochan Jayadeva Professor Ann Daly Professor Helen Reeves Richard Charnley
| The role of tobacco derived carcinogens in pancreas cancer | 2011 |
|
Julian Leathart Professor Ann Daly Professor Chris Day
| The APOC3 T-455C and C-482T promoter region polymorphisms are not associated with the severity of liver damage independently of PNPLA3 I148M genotype in patients with nonalcoholic fatty liver | 2011 |
|
Elise Andrews Professor Matthew Wright Professor Chris Day Professor Ann Daly
| A Role for the Pregnane X Receptor in Flucloxacillin-Induced Liver Injury | 2010 |
|
Professor Ann Daly Professor Farhad Kamali
| A systematic review of cost-effectiveness analyses of pharmacogenetic-guided dosing in treatment with coumarin derivatives | 2010 |
|
Dr Kate Potter Professor Heather Cordell Professor Ann Daly Professor Derek Mann Professor John Isaacs et al. | Association between anti-tumour necrosis factor treatment response and genetic variants within the TLR and NFĸB signalling pathways | 2010 |
|
Professor Ann Daly
| Drug-induced liver injury: past, present and future | 2010 |
|
Professor Ann Daly Julian Leathart Professor Alastair Burt Professor Chris Day
| Genetic variants regulating insulin receptor signalling are associated with the severity of liver damage in patients with non-alcoholic fatty liver disease | 2010 |
|
Professor Ann Daly
| Genome-wide association studies in pharmacogenomics | 2010 |
|
Ahmad Alserri Professor Ann Daly Professor Chris Day
| Homozygosity for the Patatin-Like Phospholipase-3/Adiponutrin I148M Polymorphism Influences Liver Fibrosis in Patients with Nonalcoholic Fatty Liver Disease | 2010 |
|
Dr Peter Donaldson Professor Ann Daly Jill Henderson Professor Chris Day
| Human leucocyte antigen class II genotype in susceptibility and resistance to co-amoxiclav-induced liver injury | 2010 |
|
Dr Fiona Caple Dr Liz Williams Dr Alison Spiers Dr John Tyson Brian Burtle et al. | Inter-individual variation in DNA damage and base excision repair in young, healthy non-smokers: effects of dietary supplementation and genotype | 2010 |
|
Professor Ann Daly Professor Chris Day
| Patatin-like phospholipase domain containing 3: A case in point linking genetic susceptibility for alcoholic and nonalcoholic liver disease | 2010 |
|
Professor Ann Daly
| Pharmacogenetics and human genetic polymorphisms | 2010 |
|
Professor Ann Daly
| Polymorphisms in the Tropomyosin TPM1 Short Isoform Promoter Alter Gene Expression and Are Associated With Increased Risk of Metabolic Syndrome | 2010 |
|
Professor Ann Daly
| Preempting and preventing drug-induced liver injury | 2010 |
|
Sophie Rowbotham Professor Alan Boddy Dr Chris Redfern Professor Gareth Veal Professor Ann Daly et al. | Relevance of non-synonymous CYP2C8 polymorphisms to 13-cis retinoic acid and paclitaxel hydroxylation | 2010 |
|
Dr Montserrat Briz Del Blanco Dr Katherine Talks Dr John Hanley Dr Patrick Kesteven Professor Ann Daly et al. | Reversal of warfarin-induced over-anticoagulation with individualized dosing of oral vitamin K: a pilot study | 2010 |
|
Sophie Rowbotham Professor Ann Daly Professor Gareth Veal Professor Alan Boddy
| Role of UDP-glucuronosyltransferase isoforms in 13-cis retinoic acid metabolism in humans | 2010 |
|
Professor Ann Daly Dr Peter Donaldson Dr Pallav Bhatnagar Julia Patch Professor Heather Cordell et al. | HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin | 2009 |
|
Dr Gary Beale Ahmad Alserri Dr Luca Miele Dr Gillian Patman Professor Ann Daly et al. | Claudin 10 (CLDN10) - a Candidate Suceptibility Gene for NAFLD Progression | 2009 |
|
Professor Ann Daly
| Conference scene: Initiatives of future biobanking in pharmacogenomics | 2009 |
|
Professor Farhad Kamali Professor Ann Daly
| Estimation of the Warfarin Dose with Clinical and Pharmacogenetic Data | 2009 |
|
Professor Farhad Kamali Professor Ann Daly
| Genetic and environmental factors determining clinical outcomes and cost of warfarin therapy: a prospective study | 2009 |
|
Professor Ann Daly Professor Chris Day
| Genetic Association Studies in Drug-Induced Liver Injury | 2009 |
|
Professor Farhad Kamali Professor Ann Daly
| Genotype-guided dosing of coumarin derivatives: the European pharmacogenetics of anticoagulant therapy (EU-PACT) trial design | 2009 |
|
Dr Katherine Talks Dr John Hanley Dr Patrick Kesteven Dr Peter Avery Professor Ann Daly et al. | Individualised oral vitamin K for reversal of warfarin excessive anticoagulation | 2009 |
|
Dr John Tyson Dr Fiona Caple Dr Alison Spiers Brian Burtle Professor Ann Daly et al. | Inter-individual variation in nucleotide excision repair in young adults: effects of age, adiposity, micronutrient supplementation and genotype | 2009 |
|
Professor Ann Daly
| Nomenclature for alleles of the cytochrome P450 oxidoreductase gene | 2009 |
|
Professor Ann Daly
| Pharmacogenomics of anticoagulants: Steps toward personal dosage | 2009 |
|
Ahmad Alserri Professor Ann Daly
| PNPLA3 Genotype: Relationship to Severity of Non-Alcoholic Fatty Liver Disease | 2009 |
|
Dr Stuart Kendrick Julian Leathart Elsbeth Henderson Dr Nimantha De Alwis Dr Stephen Stewart et al. | A 'loss-of-function' mutation in TIRAP, the gene encoding the Toll-like receptor adapter molecule MAL protects against fibrosis in NAFLD but not ALD | 2008 |
|
Professor Ann Daly
| Ann K Daly talks to Tarryn Greenberg, Commissioning Editor | 2008 |
|
Elise Andrews Professor Ann Daly
| Flucloxacillin-induced liver injury | 2008 |
|
Dr Peter Donaldson Dr Pallav Bhatnagar Julia Patch Jill Henderson Julian Leathart et al. | Flucloxacillin-induced liver injury: the extended MHC 57.1 haplotype as a major risk factor | 2008 |
|
Rajiv Lochan Jayadeva Professor Ann Daly Professor Helen Reeves Richard Charnley
| Genetic susceptibility in pancreatic ductal adenocarcinoma | 2008 |
|
Dr Pallav Bhatnagar Professor Chris Day Professor Ann Daly
| Genetic variants of hepatic transporters and susceptibility to drug induced liver injury | 2008 |
|
Professor Ann Daly Professor Gerard Stansby
| Increased Platelet-monocyte Aggregation in Male Claudicants with the PlA1/A2 Polymorphism of Gp IIb/IIIa | 2008 |
|
Professor Ann Daly
| Interview | 2008 |
|
Professor Ann Daly
| Pharmacogenomics applications in drug Metabolism: From genotyping to drug label-challenges? | 2008 |
|
Elise Andrews Professor Matthew Wright Professor Chris Day Professor Ann Daly
| Relevance of PXR to Flucloxacillin-induced Liver Injury | 2008 |
|
Dr Peter Donaldson Dr Pallav Bhatnagar Julia Patch Jill Henderson Julian Leathart et al. | Susceptibility to drug induced liver injury determined by HLA class II genotype | 2008 |
|
Vasileios Pagmantidis Dr Robert Shiel Professor John Mathers Professor Ann Daly Professor John Hesketh et al. | Evidence that a polymorphism within the 3'UTR of glutathione peroxidase 4 is functional and is associated with susceptibility to colorectal cancer | 2007 |
|
Dr Ruben Thanacoody Professor Ann Daly Dr Joseph Reilly Emeritus Professor Nicol Ferrier Professor Simon Thomas et al. | Factors affecting drug concentrations and QT interval during thioridazine therapy | 2007 |
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Dr Nimantha De Alwis Professor Ann Daly Julian Leathart Dr Sushma Saksena Professor Chris Day et al. | Genetic evidence that lipid trafficking plays a key role in fibrosis in non alcoholic fatty liver disease | 2007 |
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Professor Ann Daly Julian Leathart Richard Swainsbury Professor Chris Day
| Genetic Susceptibility to Diclofenac-Induced Hepatotoxicity: Contribution of UGT2B7, CYP2C8, and ABCC2 Genotypes | 2007 |
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Professor Ann Daly
| Individualized drug therapy | 2007 |
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Professor Ann Daly
| Pharmacogenetics and pharmacogenomics | 2007 |
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Professor Ann Daly
| Pharmacogenetics of oral anticoagulants | 2007 |
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Dr Ellen Hatch Elizabeth Sconce Dr Barry King Dr Hilary Wynne Professor Ann Daly et al. | Polymorphisms in genes associated with the vitamin K epoxide reductase complex do not affect warfarin dose requirement | 2007 |
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Professor Ann Daly Ahmad Alserri Julian Leathart Julia Patch Professor Chris Day et al. | The mitochondrial superoxide dismutase 2 (SOD2) targeting sequence polymorphism is associated with fibrotic NAFLD: Consistent evidence from case-control and intra-familial allelic association studies | 2007 |
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Dr Elaine Mutch Professor Ann Daly Professor Faith Williams
| The Relationship between PON1 Phenotype and PON1-192 Genotype in Detoxification of Three Oxons by Human Liver | 2007 |
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Dr Ellen Hatch Elizabeth Sconce Professor Ann Daly Professor Farhad Kamali
| A rapid genotyping method for the vitamin K epoxide reductase complex subunit 1 (VKORC1) gene | 2006 |
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Elizabeth Sconce Professor Ann Daly Dr Tayyaba Khan Dr Hilary Wynne Professor Farhad Kamali et al. | APOE genotype makes a small contribution to warfarin dose requirements | 2006 |
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Elizabeth Sconce Dr Tayyaba Khan Professor Ann Daly Dr Hilary Wynne Professor Farhad Kamali et al. | Apolipoprotein E polymorphisms do not make a clinically significant contribution to warfarin dose requirements | 2006 |
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Professor Ann Daly
| Association study of the BDNF Val66Met polymorphism with tardive dyskinesia | 2006 |
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Professor Ann Daly Dr Barry King
| Contribution of CYP2C9 to variability in vitamin K antagonist metabolism | 2006 |
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Dr Ruben Thanacoody Professor Ann Daly Dr Joseph Reilly Emeritus Professor Nicol Ferrier Professor Simon Thomas et al. | Effects of CYP2D6 genotype on QTc interval in recipients of thioridazine | 2006 |
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Professor Chris Day Julian Leathart Professor Ann Daly
| Genetic evidence for a role for gut flora in the pathogenesis of NASH in humans | 2006 |
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Dr Ruben Thanacoody Professor Ann Daly Dr Joseph Reilly Emeritus Professor Nicol Ferrier Professor Simon Thomas et al. | Genetic factors influencing steady-state plasma concentrations of thioridazine and its metabolites | 2006 |
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Professor Ann Daly Dr Barry King Julian Leathart
| Genotyping for cytochrome P450 polymorphisms | 2006 |
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Professor Ann Daly
| Significance of the minor cytochrome P450 3A isoforms | 2006 |
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Elizabeth Sconce Dr Tayyaba Khan Professor Ann Daly Dr Hilary Wynne Professor Farhad Kamali et al. | Simvastatin results in a lower warfarin dose requirement due to a reduced clearance of warfarin | 2006 |
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Elizabeth Sconce Dr Tayyaba Khan Professor Ann Daly Dr Hilary Wynne Professor Farhad Kamali et al. | The impact of simvastatin on warfarin disposition and dose requirements | 2006 |
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Dr Barry King Dr Tayyaba Khan Professor Farhad Kamali Professor Ann Daly
| [abstract] CYP2C9 polymorphisms and haplotypes: correlation with warfarin dose and metabolism | 2005 |
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Elizabeth Sconce Dr Tayyaba Khan Dr Hilary Wynne Dr Patrick Kesteven Dr Peter Avery et al. | [abstract] Pfizer poster communication prize - The influence of patient age, CYP2C9 genotype and height on warfarin dose requirements | 2005 |
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Dr Ruben Thanacoody Professor Ann Daly Dr Joseph Reilly Emeritus Professor Nicol Ferrier Professor Simon Thomas et al. | Factors affecting steady-state plasma concentrations of thioridazine and its metabolites and electrocardiographic parameters of cardiac repolarisation in patients on chronic thioridazine therapy | 2005 |
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Emerita Professor Suzanne Cholerton Professor Ann Daly
| Genetic polymorphism of manganese superoxide dismutase (MnSOD) and breast cancer susceptibility | 2005 |
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Dr Catherine Todhunter Dr Alison Sutherland Dr Peter Donaldson Professor Ann Daly Emeritus Professor Roger Francis et al. | Influence of IL-6, COL1A1, and VDR gene polymorphisms on bone mineral density in Crohn's disease | 2005 |
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Julian Leathart Professor Ann Daly
| Polymorphic organic anion transporting polypeptide 1B1 is a major determinant of repaglinide pharmacokinetics | 2005 |
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Ela Kadioglu Professor Ann Daly
| Ser326cys polymorphism in hOGG1 gene and its susceptibility to Barrett's esophagus and esophageal carcinoma | 2005 |
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Elizabeth Sconce Dr Tayyaba Khan Dr Hilary Wynne Dr Peter Avery Dr Barry King et al. | The impact of CYP2C9 and VKORC1 genetic polymorphism and patient characteristics upon warfarin dose requirements: Proposal for a new dosing regimen | 2005 |
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Professor Ann Daly
| [abstract] Contribution of polymorphisms in xenobiotic metabolism and DNA repair genes to DNA damage and cancer | 2004 |
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Vanessa Gage Professor Peter Blain Julian Leathart Professor Ann Daly Professor Faith Williams et al. | Association of DNA damage to human peripheral lymphocytes with age and MnSOD and OGG1 genotype | 2004 |
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Professor Ann Daly
| Association of metabolic gene polymorphisms with tobacco consumption in healthy controls | 2004 |
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Professor Farhad Kamali Dr Tayyaba Khan Dr Barry King Dr Patrick Kesteven Peter Wood et al. | Contribution of age, body size, and CYP2C9 genotype to anticoagulant response to warfarin | 2004 |
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Professor Ann Daly
| CYP3A5 and MDR1 genetic polymorphisms and cyclosporine pharmacokinetics after renal transplantation | 2004 |
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Professor Ann Daly Dr Barry King
| CYP3A5 phenotype-genotype correlations in a British population - Response | 2004 |
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Professor Ann Daly
| Development of analytical technology in pharmacogenetic research | 2004 |
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Professor Chris Day Professor Ann Daly
| Genetic susceptibility to alcoholic liver disease | 2004 |
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Professor Ann Daly Dr Barry King
| Genotyping of the A6986G polymorphism of CYP3A5 | 2004 |
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Professor Ann Daly Julian Leathart Professor Chris Day
| Hepatic Adducts, Circulating Antibodies, and Cytokine Polymorphisms in Patients with Diclofenac Hepatotoxicity | 2004 |
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Emerita Professor Suzanne Cholerton Professor Ann Daly
| N-Acetyltransferase (NAT2) Polymorphism and Breast Cancer Susceptibility: A Lack of Association in a Case-Control Study of Turkish Population | 2004 |
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Professor Ann Daly
| Pharmacogenetics of the cytochromes P450 | 2004 |
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Professor Ann Daly Dr George Rylance
| Protein substitutes for PKU: What's new? | 2004 |
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Emma Davis Vanessa Gage Professor Ann Daly Professor Faith Williams
| The contribution of genotype to DNA damage in lymphocytes from healthy volunteers | 2004 |
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Professor Farhad Kamali Dr Tayyaba Khan Dr Barry King Professor Ann Daly Dr Hilary Wynne et al. | The impact of patient age and genetic polymorphism of CYP2C9 on warfarin dose requirements | 2004 |
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Dr Barry King Dr Tayyaba Khan Professor Farhad Kamali Professor Ann Daly
| Upstream and coding region CYP2C9 polymorphisms: Correlation with warfarin dose and metabolism | 2004 |
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Professor Ann Daly Dr Santosh Gupta
| Warfarin and celecoxib interaction in the setting of cytochrome P450 (CYP2C9) polymorphism with bleeding complication | 2004 |
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Professor Ann Daly Julian Leathart Professor Chris Day
| A "loss-of-function" polymorphism in ICAM-1 protects heavy drinkers from alcoholic liver disease | 2003 |
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Dr Stuart Dunn Professor Ann Daly Dr Trevor Thomas
| Altered tropomyosin expression in essential hypertension | 2003 |
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Professor Ann Daly
| Candidate gene case-control studies | 2003 |
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Dr Barry King Julian Leathart Dr Elaine Mutch Professor Faith Williams Professor Ann Daly et al. | CYP3A5 phenotype-genotype correlations in a British population | 2003 |
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Professor Ann Daly
| Cytochrome P450 polymorphisms and the individualization of drug treatment | 2003 |
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Dr Elaine Mutch Professor Ann Daly Julian Leathart Professor Peter Blain Professor Faith Williams et al. | Do multiple cytochrome P450 isoforms contribute to parathion metabolism in man? | 2003 |
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Professor Ann Daly Julian Leathart Dr Beate Haugk Professor David Jones Professor Alastair Burt et al. | Evidence that alcoholic liver disease is due to immune mechanisms in genetically susceptible drinkers | 2003 |
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Dr Stephen Stewart Professor Ann Daly Professor David Jones Julian Leathart Professor Chris Day et al. | Genetic and epigenetic factors in autoimmune reactions toward cytochrome P4502E1 in alcoholic liver disease | 2003 |
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Dr Sushma Saksena Julian Leathart Professor Alastair Burt Emeritus Professor Oliver James Professor Ann Daly et al. | Genetic evidence supporting the two-hit model of NASH pathogenesis | 2003 |
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Professor Ann Daly
| Genetic Regulation of Warfarin Metabolism and Response | 2003 |
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Professor Ann Daly
| Impact of cytochrome P450 3A5 genetic polymorphism on tacrolimus doses and concentration-to-dose ratio in renal transplant recipients | 2003 |
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Dr Ruben Thanacoody Professor Ann Daly Professor Simon Thomas
| Influence of CYP2D6 and CYP2C19 genotypes on the QTc intervals of psychiatric patients taking thioridazine | 2003 |
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Dr Ruben Thanacoody Professor Ann Daly Professor Simon Thomas
| Influence of CYP2D6 genotype on the QTc interval and plasma concentration of thioridazine and its metabolites of psychiatric patients taking chronic therapy. | 2003 |
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Dr Sushma Saksena Julian Leathart Professor Ann Daly Professor Chris Day
| Manganese dependent superoxide dismutase (SOD2) targeting sequence polymorphism is associated with advanced fibrosis in patients with non-alcoholic fatty liver disease | 2003 |
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Dr Barry King Dr Tayyaba Khan Professor Farhad Kamali Professor Ann Daly
| Novel CYP2C9 polymorphisms and their relationship to warfarin dose requirements | 2003 |
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Alison Sutherland-Craggs Dr John Mansfield Dr Peter Donaldson Professor Ann Daly Dr Nicholas Thompson et al. | Osteoporosis in Crohn's disease is not determined by vitamin D receptor and interleukin-6 genotype | 2003 |
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Professor Ann Daly Dr Barry King
| Pharmacogenetics of oral anticoagulants | 2003 |
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Professor Ann Daly
| Pharmacogenetics of the major polymorphic metabolizing enzymes | 2003 |
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Julian Leathart Professor Ann Daly
| Polymorphism in CYP2C8 is associated with reduced plasma concentrations of repaglinide | 2003 |
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Julian Leathart Professor Chris Day Professor Ann Daly
| Relationship of UGT2B7 genotype with diclofenac hepatotoxicity | 2003 |
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Dr Elaine Mutch Dr Lindsey Ferrie Christopher Pedder Professor Faith Williams Professor Ann Daly et al. | The role of metabolism in determining the genotoxicity of organophosphate pesticides | 2003 |
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Professor Farhad Kamali Professor Ann Daly Dr Hilary Wynne
| Warfarin sensitivity: Be aware of genetic influence | 2003 |
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Julian Leathart Professor Chris Day Professor Ann Daly
| Association of udp-glucuronosyltransferase (UGT) 2B7 genotype with diclofenac-induced hepatotoxicity | 2002 |
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Professor Ann Daly
| Common allelic variants of cytochrome P4503A4 and their prevalence in different populations | 2002 |
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Dr Namrata Bahadur Julian Leathart Dr Elaine Mutch Dr Stuart Dunn Professor Faith Williams et al. | CYP2C8 polymorphisms in Caucasians and their relationship with paclitaxel 6α-hydroxylase activity in human liver microsomes | 2002 |
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Professor Ann Daly Professor Chris Day
| CYP2C9 polymorphism and warfarin dose requirements | 2002 |
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Professor Ann Daly
| CYP2D6 deficiency, a factor in ecstasy related deaths? | 2002 |
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Emerita Professor Suzanne Cholerton Professor Ann Daly
| Cytochrome P450 CYP1B1 and catechol O-methyltransferase (COMT) genetic polymorphisms and breast cancer susceptibility in a Turkish population | 2002 |
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Professor Ann Daly Julian Leathart Dr Beate Haugk Professor David Jones Professor Alastair Burt et al. | Evidence that alcoholic liver disease is due to immune mechanisms in genetically susceptible drinkers | 2002 |
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Professor Chris Day Dr Sushma Saksena Julian Leathart Professor Alastair Burt Emeritus Professor Oliver James et al. | Genetic evidence supporting the two-hit model of NASH pathogenesis | 2002 |
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Professor Chris Day Julian Leathart Professor Ann Daly
| Genetic evidence that fatty liver is involved in the pathogenesis of advanced alcoholic liver disease | 2002 |
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Professor Ann Daly
| Meta- and pooled analyses of the effects of glutathione S-transferase M1 polymorphisms and smoking on lung cancer risk | 2002 |
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Alison Sutherland-Craggs Dr John Mansfield Dr Mark Hudson Professor Ann Daly Emeritus Professor Roger Francis et al. | Osteoporosis in Crohn's disease is not determined by NOD2 genotype [abstract] | 2002 |
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Professor Ann Daly Emeritus Professor Nicol Ferrier
| Pharmacogenetics of tardive dyskinesia: Combined analysis of 780 patients supports association with dopamine D3 receptor gene Ser9Gly polymorphism | 2002 |
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Professor Ann Daly Professor Chris Day Dr Peter Donaldson
| Polymorphisms in immunoregulatory genes: towards individualised immunosupressive therapy? | 2002 |
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Ragen Pfeiffer Professor Ann Daly
| Pooled analysis and meta-analysis of glutathione S-transferase M1 and bladder cancer: A HuGE review | 2002 |
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Dr Stephen Stewart Julian Leathart Professor Ann Daly Professor Chris Day
| Valine-alanine manganese superoxide dismutase polymorphism is not associated with alcohol-induced oxidative stress or liver fibrosis | 2002 |
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Dr Stephen Stewart Professor Ann Daly Julian Leathart Professor David Jones Professor Chris Day et al. | A polymorphism in CTLA-4 is associated with the presence of anti-CYP2E1 antibody titres in patients with alcoholic liver disease | 2001 |
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Professor Chris Day Julian Leathart Professor Ann Daly Dr Mark Hudson
| Association of a 5'-flanking region polymorphism in the interleukin-4 gene with Crohn’s disease in a British population. | 2001 |
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Professor Chris Day Julian Leathart Professor Ann Daly Dr Mark Hudson
| Association of single nucleotide polymorphisms in the interleukin-4 gene and interleukin-4 receptor gene with Crohn's disease in a British population | 2001 |
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Professor Ann Daly Professor Chris Day
| Candidate gene case-control association studies: advantages and potential pitfalls | 2001 |
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Professor Ann Daly
| Current smoking, occupation, N-acetyltransferase-2 and bladder cancer: A pooled analysis of genotype-based studies | 2001 |
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Dr Mark Welfare Professor Ann Daly
| Genotype for CYP1A2 and Ah receptor and risk of colorectal cancer in north east England | 2001 |
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Professor Ann Daly
| Human cytochrome P-450 (CYP) genes: A web page for the nomenclature of alleles | 2001 |
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Professor Ann Daly
| Metabolic gene polymorphism frequencies in control populations | 2001 |
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Professor Ann Daly Dr Andrew Hall
| Pharmacogenetics of cytotoxic drugs | 2001 |
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Professor Ann Daly
| Polymorphisms in CYP2D6 duplication-negative individuals with the ultrarapid metabolizer phenotype: a role for the CYP2D6*35 allele in ultrarapid metabolism? | 2001 |
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Dr Kaushik Agarwal Professor Ann Daly Julian Leathart Dr Mark Hudson Professor Chris Day et al. | Polymorphisms of immunoregulatory genes: A step towards individually tailored immunosuppression? | 2001 |
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Emma Davis Professor Ann Daly Professor Faith Williams
| Quantitation of in vitro DNA damage using the comet assay | 2001 |
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Dr Andrew Harbottle Professor Ann Daly Dr Kathryn Atherton Professor Frederick Campbell
| Role of glutathione S-transferase P1, P-glycoprotein and multidrug resistance-associated protein 1 in acquired doxorubicin resistance | 2001 |
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Dr Alison Sutherland Professor Chris Day Dr Mark Welfare Professor Ann Daly Dr John Mansfield et al. | Role of polymorphisms in the interleukin-10 gene in determining disease susceptibility and phenotype in inflamatory bowel disease | 2001 |
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Professor Ann Daly
| Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression | 2001 |
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Professor Chris Day Professor Ann Daly
| The genetic basis for non-alcoholic and alcoholic steatohepatitis. | 2001 |
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Professor Ann Daly
| The human pregnane X receptor: genomic structure and identification and functional characterization of natural allelic variants | 2001 |
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Professor David Jones Professor Ann Daly Emeritus Professor Oliver James Dr Bijayeswar Vaidya Professor Simon Pearce et al. | CTLA-4 gene polymorphism confers susceptibility to primary biliary cirrhosis | 2000 |
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Professor Gary Ford Professor Ann Daly
| CYP2D6 and CYP2C19 genotypes of patients with terodilin cardiotoxicity identified through the yellow card system | 2000 |
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Professor Gary Ford Professor Ann Daly
| CYP2D6 and CYP2C19 genotypes of patients with terodiline cardiotoxicity identified through the yellow card system | 2000 |
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Professor Ann Daly Emeritus Professor Nicol Ferrier
| Homozygosity for the Gly-9 variant of the dopamine D3 receptor and risk for tardive dyskinesia in schizophrenic patients | 2000 |
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Professor Ann Daly
| Human cytochrome P450 (CYP) genes: recommendations for the nomenclature of alleles | 2000 |
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Professor Ann Daly
| Identification of human cytochrome P450 isoforms that contribute to all-trans-retinoic acid 4-hydroxylation | 2000 |
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Professor Ann Daly Professor Margaret Bassendine Professor Chris Day
| Interleukin 10 promoter region polymorphisms and susceptibility to advanced alcoholic liver disease | 2000 |
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Joanne Smart Professor Ann Daly
| Lung cancer risk in relation to genetic polymorphisms of microsomal epoxide hydrolase among African-Americans and Caucasians in Los Angeles County | 2000 |
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Sandra Campbell Dr Steven Laval Professor Ann Daly
| Polymorphisms of the CYP2D6 gene increase susceptibility to ankylosing spondylitis | 2000 |
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Professor Chris Day Julian Leathart Professor Ann Daly
| Relationship of polymorphism in CYP2C9 to genetic susceptibility to diclofenac-induced hepatitis | 2000 |
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Dr Mark Welfare Professor Margaret Bassendine Professor Ann Daly
| The effect of NAT2 genotype and gender on the metabolism of caffeine in nonsmoking subjects | 2000 |
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Joanne Smart Professor Ann Daly
| Variation in induced CYP1A1 levels: Relationship to CYP1A1, Ah receptor and GSTM1 polymorphisms | 2000 |
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Professor Chris Day Dr Patrick Kesteven Professor Ann Daly
| Association of polymorphisms in the cytochrome P450 CYP2C9 with warfarin dose requirement and risk of bleeding complications | 1999 |
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Dr Kaushik Agarwal Professor David Jones Professor Ann Daly Professor Margaret Bassendine
| CTLA-4 gene polymorphism and chronicity in viral hepatitis | 1999 |
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Dr Kaushik Agarwal Professor David Jones Professor Ann Daly Professor Margaret Bassendine Dr Mark Hudson et al. | CTLA-4 gene polymorphism and susceptibility to inflammatory bowel disease (IBD) | 1999 |
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Emeritus Professor Robert Perry Professor Ian McKeith Dr Andrew Fairbairn Professor Jim Edwardson Professor Ann Daly et al. | CYP2D6 is associated with Parkinson's disease but not with dementia with Lewy Bodies or Alzheimer's disease | 1999 |
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Dr Mark Welfare Emeritus Professor Murray Aitkin Professor Margaret Bassendine Professor Ann Daly
| Detailed modelling of caffeine metabolism and examination of the CYP1A2 gene: Lack of a polymorphism in CYP1A2 in Caucasians | 1999 |
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Professor Ann Daly
| Genetic epidemiology of environmental toxicity and cancer susceptibility: Human allelic polymorphisms in drug-metabolizing enzyme genes, their functional importance, and nomenclature issues | 1999 |
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Professor Ann Daly
| Genetic variation of CYP2A6, smoking, and risk of cancer | 1999 |
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Professor Ann Daly Dr Mark Welfare
| Genotype for codon 105 polymorphism of GSTP1 does not predict susceptibility to UC | 1999 |
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Professor Ann Daly Dr Mark Welfare
| GSTP1 is not a susceptibility gene for UC | 1999 |
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Professor Ann Daly
| Low frequency of CYP2A6 gene polymorphism as revealed by a one-step polymerase chain reaction method | 1999 |
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Professor Margaret Bassendine Professor Ann Daly
| Polymorphisms in GSTP1, GSTM1, and GSTT1 and susceptibility to colorectal cancer | 1999 |
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Mike Cole Emerita Professor Suzanne Cholerton Professor Ann Daly Professor Andrew Pearson Professor Alan Boddy et al. | The effect of fluconazole on cyclophosphamide metabolism in children | 1999 |
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Professor David Jones Emerita Professor Julia Newton Professor Ann Daly Professor Chris Day Emeritus Professor Oliver James et al. | Tumour necrosis factor-α promoter polymorphisms in primary biliary cirrhosis | 1999 |
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Professor Chris Day Dr Patrick Kesteven Professor Ann Daly
| Warfarin dose requirement and CYP2C9 polymorphisms - Reply | 1999 |
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Professor Ann Daly Professor Margaret Bassendine Emeritus Professor Oliver James Professor Chris Day
| The RsaI polymorphism of CYP2E1 and susceptibility to alcoholic liver disease in Caucasians: Effect on age of presentation and dependence on alcohol dehydrogenase genotype | 1998 |
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Professor Ann Daly
| Lung cancer risk in relation to the CYP2E1 Rsa I genetic polymorphism among African-Americans and Caucasians in Los Angeles County | 1996 |
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Professor Alan Boddy Emerita Professor Suzanne Cholerton Professor Ann Daly Professor Andrew Pearson
| Identification of the major human hepatic cytochrome P450 involved in activation and N-dechloroethylation of ifosfamide | 1994 |
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Professor Alan Boddy Emerita Professor Suzanne Cholerton Professor Ann Daly Professor Janice Ellis Julian Leathart et al. | The pharmacogenetics of chemical carcinogenesis | 1992 |
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Dr Chris Redfern Professor Ann Daly
| Cellular retinoic acid-binding protein from neonatal rat skin: Purification and analysis | 1990 |
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Professor Ann Daly Dr Chris Redfern
| Identification and analysis of retinoic acid-binding proteins and receptors from nuclei of mammalican cells | 1990 |
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Dr Chris Redfern Professor Ann Daly Carole Todd
| The biological activity of retinoids in melanoma cells: Induction of expression of retinoic acid receptor-β by retinoic acid in S91 melanoma cells | 1990 |
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Professor Jonathan Rees Professor Ann Daly Dr Chris Redfern
| Differential expression of the alpha and beta retinoic acid receptors in tissues of the rat | 1989 |
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Professor Ann Daly Professor Jonathan Rees Dr Chris Redfern
| Nuclear retinoic acid binding proteins and receptors in retinoic acid responsive cell lines | 1989 |
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Professor Ann Daly Dr Chris Redfern
| Retinoic acid receptor expression in some retinoic acid responsive cell-lines | 1989 |
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Professor Ann Daly Dr Chris Redfern
| Purification and properties of cellular retinois acid-binding protein from neonatal rat skin | 1988 |
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Professor Ann Daly Dr Chris Redfern
| Characterisation of a retinoic-acid-binding component from F9 embryonal-carcinoma-cell nuclei | 1987 |
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Professor Ann Daly Dr Chris Redfern
| The binding of retinoic acid to nuclei and nuclear subfractions | 1985 |
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