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Browsing publications by Professor Alastair Hawkins

Newcastle AuthorsTitleYearFull text
Dr David Wilkinson
Angie Habgood
Dr Heather Lamb
Paul Thompson
Professor Alastair Hawkins
et al.		Matriptase Induction of Metalloproteinase-Dependent Aggrecanolysis In Vitro and In Vivo: Promotion of Osteoarthritic Cartilage Damage by Multiple Mechanisms2017
Paul Thompson
Professor Alastair Hawkins
Study of the Phosphoryl-Transfer Mechanism of Shikimate Kinase by NMR Spectroscopy2016
Dr Artur Rogowski
Jon Briggs
Dr Elisabeth Lowe
Dr Arnaud Basle
Carl Morland
et al.		Glycan complexity dictates microbial resource allocation in the large intestine2015
Paul Thompson
Professor Alastair Hawkins
Irreversible covalent modification of type I dehydroquinase with a stable Schiff base2015
Paul Thompson
Professor Alastair Hawkins
Exploring the Water-Binding Pocket of the Type II Dehydroquinase Enzyme in the Structure-Based Design of Inhibitors2014
Paul Thompson
Professor Alastair Hawkins
Insights into substrate binding and catalysis in bacterial type I dehydroquinase2014
Dr Heather Lamb
Professor Alastair Hawkins
Mechanistic insight into the reaction catalysed by bacterial type II dehydroquinases2014
Professor Alastair Hawkins
Mycobacterium tuberculosis Shikimate Kinase Inhibitors: Design and Simulation Studies of the Catalytic Turnover2013
Dr Heather Lamb
Paul Thompson
Professor Alastair Hawkins
Crystal structure of the dimer of two essential Salmonella typhimurium proteins, YgjD and YeaZ and calorimetric evidence for the formation of a ternary YgjD-YeaZ-YjeE complex2013
Shaun Martin
Dr Heather Lamb
Paul Thompson
Professor Penny Lovat
Professor Alastair Hawkins
et al.		Inducing apoptosis of cancer cells using small-molecule plant compounds that bind to GRP782013
Dr Heather Lamb
Professor Alastair Hawkins
Mechanistic Basis of the Inhibition of Type II Dehydroquinase by (2S)- and (2R)-2-Benzyl-3-dehydroquinic Acids2013
Dr Heather Lamb
Professor Alastair Hawkins
Interaction between relaxase MbeA and accessory protein MbeC of the conjugally mobilizable plasmid ColE12012
Professor Alastair Hawkins
Synthesis of 3-alkyl enol mimics inhibitors of type II dehydroquinase: factors influencing their inhibition potency2012
Dr Heather Lamb
Professor Alastair Hawkins
A Prodrug Approach for Improving Antituberculosis Activity of Potent Mycobacterium tuberculosis Type II Dehydroquinase Inhibitors2011
Dr Heather Lamb
Professor Alastair Hawkins
Crystallographic and microcalorimetric analyses reveal the structural basis for high arginine specificity in the Salmonella enterica serovar Typhimurium periplasmic binding protein STM43512011
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