Toggle Main Menu Toggle Search

Open Access padlockePrints

Browsing publications by Dr Lindi Chen.

Newcastle AuthorsTitleYearFull text
Harriet Southgate
Dr Lindi Chen
Professor Nicola Curtin
Professor Deborah Tweddle
Increased replication stress determines ATR inhibitor sensitivity in neuroblastoma cells2021
Harriet Southgate
Dr Lindi Chen
Professor Deborah Tweddle
Professor Nicola Curtin
ATR inhibition potentiates parp inhibitor cytotoxicity in high risk neuroblastoma cell lines by multiple mechanisms2020
Swathi Merugu
Dr Lindi Chen
Elizabeth Gavens
Hany Gabra
Dr Al Gabriel
et al.
Detection of circulating and disseminated neuroblastoma cells using the Imagestream Imaging Flow Cytometer for use as predictive and pharmacodynamic biomarkers2020
Harriet Southgate
Dr Lindi Chen
Professor Nicola Curtin
Professor Deborah Tweddle
Targeting the DNA Damage Response for the Treatment of High Risk Neuroblastoma2020
Dr Lindi Chen
Philip Berry
Dr Jennifer Bonner
Calum Kirk
Dr Katrina Wood
et al.
Preclinical evaluation of the first intravenous small molecule MDM2 antagonist alone and in combination with temozolomide in neuroblastoma2019
Dr Lindi Chen
Arman Esfandiari
Professor John Lunec
Professor Deborah Tweddle
Characterisation of the p53 pathway in cell lines established from TH-MYCN transgenic mouse tumours2018
Dr Lindi Chen
Philip Berry
Dr Jennifer Bonner
Dr Katrina Wood
Professor Gareth Veal
et al.
In vivo evaluation of the intravenous MDM2-p53 antagonist RO6839921 alone and in combination with temozolomide in TP53 wild-type orthotopic models of neuroblastoma2017
Dr Al Gabriel
Dr Lindi Chen
Dr Sirintra Nakjang
Dr Daniel Williamson
Professor Deborah Tweddle
et al.
Combined Copy Number and Gene Expression Profiling in High Rick Neuroblastoma: A CCLG Pilot Biological Study2016
Dr Lindi Chen
Angharad Humphreys
Dr Lisa Turnbull
Dr Nicholas Bown
Professor Deborah Tweddle
et al.
Identification of different ALK mutations in a pair of neuroblastoma cell lines established at diagnosis and relapse2016
Angharad Humphreys
Dr Al Gabriel
Dr Nicholas Bown
Dr Lindi Chen
Dr David Jamieson
et al.
Imaging flow-cytometer based detection of ALK and MDM2 amplification in neuroblastoma cell lines2016
Dr Lindi Chen
Professor Deborah Tweddle
Neuroblastoma and the p53 Pathway2015
Dr Lindi Chen
Professor Deborah Tweddle
Neuroblastoma and the p53 pathway 2015
Dr Lindi Chen
Professor Herbie Newell
Professor John Lunec
Professor Deborah Tweddle
Pre-clinical evaluation of the MDM2-p53 antagonist RG7388 alone and in combination with chemotherapy in neuroblastoma2015
Laura Evans
Dr Lindi Chen
Dr Elaine Willmore
Professor Herbie Newell
Professor Deborah Tweddle
et al.
SKP2 is a direct transcriptional target of MYCN and a potential therapeutic target in neuroblastoma2015
Dr Lindi Chen
Meeting report: 3rd Neuroblastoma Research Symposium, Liverpool, 6-7th November, 20132014
Dr Lindi Chen
Dr Yan Zhao
Dr Gail Halliday
Philip Berry
Professor Herbie Newell
et al.
Structurally diverse MDM2-p53 antagonists act as modulators of MDR-1 function in neuroblastoma2014
Dr Lindi Chen
Professor Deborah Tweddle
p53, SKP2, and DKK3 as MYCN Target Genes and Their Potential Therapeutic Significance2012
Dr Emma Bell
Dr Lindi Chen
Professor John Lunec
Professor Deborah Tweddle
MYCN oncoprotein targets and their therapeutic potential2010
Dr Lindi Chen
Dr Laura Gamble
Professor John Lunec
Professor Deborah Tweddle
p53 is a direct transcriptional target of MYCN in neuroblastoma2010
Dr Lindi Chen
Professor Archibald Malcolm
Dr Katrina Wood
Mike Cole
Professor Andrew Pearson
et al.
p53 is nuclear and functional in both undifferentiated and differentiated neuroblastoma2007