Publications by Dr Lindi Chen - ePrints

Browsing publications by Dr Lindi Chen.

Newcastle Authors	Title	Year
Dr Lindi Chen Professor Deborah Tweddle	Combination Therapies Targeting ALK-aberrant Neuroblastoma in Preclinical Models	2023
Harriet Southgate Dr Lindi Chen Professor Nicola Curtin Professor Deborah Tweddle	Increased replication stress determines ATR inhibitor sensitivity in neuroblastoma cells	2021
Harriet Southgate Dr Lindi Chen Professor Deborah Tweddle Professor Nicola Curtin	ATR inhibition potentiates parp inhibitor cytotoxicity in high risk neuroblastoma cell lines by multiple mechanisms	2020
Swathi Merugu Dr Lindi Chen Elizabeth Gavens Hany Gabra Dr Al Gabriel et al.	Detection of circulating and disseminated neuroblastoma cells using the Imagestream Imaging Flow Cytometer for use as predictive and pharmacodynamic biomarkers	2020
Harriet Southgate Dr Lindi Chen Professor Nicola Curtin Professor Deborah Tweddle	Targeting the DNA Damage Response for the Treatment of High Risk Neuroblastoma	2020
Dr Lindi Chen Philip Berry Dr Jennifer Bonner Calum Kirk Dr Katrina Wood et al.	Preclinical evaluation of the first intravenous small molecule MDM2 antagonist alone and in combination with temozolomide in neuroblastoma	2019
Dr Lindi Chen Arman Esfandiari Professor John Lunec Professor Deborah Tweddle	Characterisation of the p53 pathway in cell lines established from TH-MYCN transgenic mouse tumours	2018
Dr Lindi Chen Philip Berry Dr Jennifer Bonner Dr Katrina Wood Professor Gareth Veal et al.	In vivo evaluation of the intravenous MDM2-p53 antagonist RO6839921 alone and in combination with temozolomide in TP53 wild-type orthotopic models of neuroblastoma	2017
Dr Al Gabriel Dr Lindi Chen Dr Sirintra Nakjang Dr Daniel Williamson Professor Deborah Tweddle et al.	Combined Copy Number and Gene Expression Profiling in High Rick Neuroblastoma: A CCLG Pilot Biological Study	2016
Dr Lindi Chen Angharad Humphreys Dr Lisa Turnbull Dr Nicholas Bown Professor Deborah Tweddle et al.	Identification of different ALK mutations in a pair of neuroblastoma cell lines established at diagnosis and relapse	2016
Angharad Humphreys Dr Al Gabriel Dr Nicholas Bown Dr Lindi Chen Dr David Jamieson et al.	Imaging flow-cytometer based detection of ALK and MDM2 amplification in neuroblastoma cell lines	2016
Dr Lindi Chen Professor Deborah Tweddle	Neuroblastoma and the p53 Pathway	2015
Dr Lindi Chen Professor Deborah Tweddle	Neuroblastoma and the p53 pathway	2015
Dr Lindi Chen Professor Herbie Newell Professor John Lunec Professor Deborah Tweddle	Pre-clinical evaluation of the MDM2-p53 antagonist RG7388 alone and in combination with chemotherapy in neuroblastoma	2015
Laura Evans Dr Lindi Chen Dr Elaine Willmore Professor Herbie Newell Professor Deborah Tweddle et al.	SKP2 is a direct transcriptional target of MYCN and a potential therapeutic target in neuroblastoma	2015
Dr Lindi Chen	Meeting report: 3rd Neuroblastoma Research Symposium, Liverpool, 6-7th November, 2013	2014
Dr Lindi Chen Dr Yan Zhao Dr Gail Halliday Philip Berry Professor Herbie Newell et al.	Structurally diverse MDM2-p53 antagonists act as modulators of MDR-1 function in neuroblastoma	2014
Dr Lindi Chen Professor Deborah Tweddle	p53, SKP2, and DKK3 as MYCN Target Genes and Their Potential Therapeutic Significance	2012
Dr Emma Bell Dr Lindi Chen Professor John Lunec Professor Deborah Tweddle	MYCN oncoprotein targets and their therapeutic potential	2010
Dr Lindi Chen Dr Laura Gamble Professor John Lunec Professor Deborah Tweddle	p53 is a direct transcriptional target of MYCN in neuroblastoma	2010
Dr Lindi Chen Professor Archibald Malcolm Dr Katrina Wood Mike Cole Professor Andrew Pearson et al.	p53 is nuclear and functional in both undifferentiated and differentiated neuroblastoma	2007