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Browsing publications by Dr Daniel Williamson.

Newcastle AuthorsTitleYearFull text
Dr Stephen Crosier
Dr Debbie Hicks
Dr Ed Schwalbe
Dr Daniel Williamson
Amanda Smith
et al.
Advanced molecular pathology for rare tumours: A national feasibility study and model for centralised medulloblastoma diagnostics2021
Dr Debbie Hicks
Dr Reza Rafiee
Dr Ed Schwalbe
Dr Christopher Howell
Dr Janet Lindsey
et al.
The molecular landscape and associated clinical experience in infant medulloblastoma: prognostic significance of second-generation subtypes2021
Dr Matthew Selby
Dr Daniel Williamson
Professor Steven Clifford
Erratum: Author Correction: VEGFC negatively regulates the growth and aggressiveness of medulloblastoma cells (Communications biology (2020) 3 1 (579))2020
Dr Martina Finetti
Dr Daniel Williamson
Locoregionally administered B7-H3-targeted CAR T cells for treatment of atypical teratoid/rhabdoid tumors2020
Yura Grabovska
Dr Daniel Williamson
Molecular subgrouping of Atypical Teratoid/Rhabdoid Tumors (ATRT) – a reinvestigation and current consensus2020
Dr Yura Grabovska
Dr Stephen Crosier
Dr Martina Finetti
Dr Ed Schwalbe
Dr Rebecca Hill
et al.
Pediatric pan-central nervous system tumor analysis of immune-cell infiltration identifies correlates of antitumor immunity2020
Dr Rebecca Hill
Dr Stacey Richardson
Dr Ed Schwalbe
Dr Debbie Hicks
Dr Janet Lindsey
et al.
Time, pattern, and outcome of medulloblastoma relapse and their association with tumour biology at diagnosis and therapy: a multicentre cohort study2020
Dr Martina Finetti
Yura Grabovska
Professor Simon Bailey
Dr Daniel Williamson
Translational Genomics of Malignant Rhabdoid Tumours: Current Impact and Future Possibilities2020
Dr Martina Finetti
Dr Daniel Williamson
Comprehensive Analysis of Chromatin States in Atypical Teratoid/Rhabdoid Tumor Identifies Diverging Roles for SWI/SNF and Polycomb in Gene Regulation2019
Dr Rebecca Hill
Professor Steven Clifford
Yura Grabovska
Dr Daniel Williamson
DNA methylation-based profiling for paediatric CNS tumour diagnosis and treatment: a population-based study2019
Dr Ed Schwalbe
Dr Daniel Williamson
Dr Janet Lindsey
Dr Rebecca Hill
Dr Debbie Hicks
et al.
Second-generation molecular subgrouping of medulloblastoma: an international meta-analysis of Group 3 and Group 4 subtypes2019
Dr Daniel Williamson
Dr Christopher Jones
Professor Steven Clifford
Biological material collection to advance translational research and treatment of children with CNS tumours: position paper from the SIOPE Brain Tumour Group2018
Dr Ed Schwalbe
Dr Debbie Hicks
Dr Reza Rafiee
Dr Matthew Bashton
Dr Amir Enshaei
et al.
Minimal methylation classifier (MIMIC): A novel method for derivation and rapid diagnostic detection of disease-associated DNA methylation signatures2017
Dr Ed Schwalbe
Dr Janet Lindsey
Dr Sirintra Nakjang
Dr Stephen Crosier
Amanda Smith
et al.
Novel molecular subgroups for clinical classification and outcome prediction in childhood medulloblastoma: a cohort study2017
Dr Matthew Selby
Dr Daniel Williamson
Professor Steven Clifford
TAp73 is a marker of glutamine addiction in medulloblastoma2017
Dr Stephen Crosier
Dr Debbie Hicks
Dr Ed Schwalbe
Dr Daniel Williamson
Sarah Nicholson
et al.
Centralised Molecular Pathology for Rare Tumours: A National Feasibility Study of Real-Time Medulloblastoma Diagnostics2016
Dr Al Gabriel
Dr Lindi Chen
Dr Sirintra Nakjang
Dr Daniel Williamson
Professor Deborah Tweddle
et al.
Combined Copy Number and Gene Expression Profiling in High Rick Neuroblastoma: A CCLG Pilot Biological Study2016
Dr Martina Finetti
Dr Stephen Crosier
Dr Daniel Williamson
Dual Targeting of PDGFR alpha and FGFR1 Displays Synergistic Efficacy in Malignant Rhabdoid Tumors2016
Dr Debbie Hicks
Dr Ed Schwalbe
Dr Stephen Crosier
Professor Simon Bailey
Dr Daniel Williamson
et al.
Identification of medulloblastoma molecular subgroups using metabolite profiles2016
Dr Martina Finetti
Matthew Selby
Dr Matthew Bashton
Dr Ruth Cranston
Dr Stephen Crosier
et al.
Integrated pathway analysis of malignant rhabdoid tumour identifies key SMARCB1-pathways and therapeutic opportunities2016
Dr Martina Finetti
Alicia Del Carpio Pons
James Barker
James Wood
Dr Sirintra Nakjang
et al.
Integrated pathway analysis of rhabdoid tumor subtypes identifies key SMARCB1-dependencies and therapeutic opportunities2016
Matthew Selby
Dr Martina Finetti
Dr Matthew Bashton
Dr Ruth Cranston
Alicia Del Carpio Pons
et al.
Investigating the biology of atypical teratoid/rhabdoid tumors by whole genome CRISPR/CAS9 screening2016
Dr Janet Lindsey
Dr Rebecca Hill
Dr Ed Schwalbe
Dr Christopher Howell
Dr Reza Rafiee
et al.
Molecular and Prognostic Heterogeneity within MYC and MYCN Amplified Medulloblastomas2016
Dr Ed Schwalbe
Dr Debbie Hicks
Dr Reza Rafiee
Dr Matthew Bashton
Dr Amir Enshaei
et al.
Routine Diagnostic Medulloblastoma Subgrouping Using Low-Cost, Low-Input DNA Methylomics: Application to Trials Cohorts Previously Refractory-to-Analysis2016
Dr Ed Schwalbe
Dr Debbie Hicks
Dr Reza Rafiee
Dr Matthew Bashton
Dr Amir Enshaei
et al.
Routine molecular subgrouping of medulloblastoma: Bridging the divide between research and the clinic using low-cost, mass spectrometry-based DNA methylomics2016
Dr Debbie Hicks
Dr Reza Rafiee
Dr Ed Schwalbe
Dr Christopher Howell
Dr Janet Lindsey
et al.
Subgroup-Directed Stratification of Risk in Infant Medulloblastoma2016
Dr Daniel Williamson
Dr Janet Lindsey
Dr Debbie Hicks
Dr Stephen Crosier
Amanda Smith
et al.
The Transcriptional Landscape of Medulloblastoma: Group 3 and Group 4 Tumours Comprise a Single Clinically Significant Expression Continuum2016
Dr Rebecca Hill
Dr Janet Lindsey
Dr Ed Schwalbe
Dr Karen Barker
Dr Daniel Williamson
et al.
Combined MYC and P53 Defects Emerge at Medulloblastoma Relapse and Define Rapidly Progressive, Therapeutically Targetable Disease2015
Dr Janet Lindsey
Dr Ed Schwalbe
Matthew Selby
Dr James Hayden
Dr Daniel Williamson
et al.
Cross-species epigenetics identifies a critical role for VAV1 in SHH subgroup medulloblastoma maintenance2015
Dr Lindsay Nicholson
Elizabeth Matheson
Lynne Minto
Christopher Keilty
Maryna Sanichar
et al.
Quantitative proteomic analysis reveals maturation as a mechanism underlying glucocorticoid resistance in B lineage ALL and re-sensitization by JNK inhibition2015
Dr Janet Lindsey
Dr Ed Schwalbe
Sandeep Potluri
Professor Simon Bailey
Dr Daniel Williamson
et al.
TERT promoter mutation and aberrant hypermethylation are associated with elevated expression in medulloblastoma and characterise the majority of non-infant SHH subgroup tumours2014
Dr Martina Finetti
Alicia Del Carpio Pons
Ben Skalkoyannis
Matthew Selby
Amanda Smith
et al.
A Systems Biology Approach to Identify Mechanism of Tumourigenesis Caused by Loss of SMARCB1 in Malignant Rhabdoid Tumors (BACR28)2014
Dr Martina Finetti
Matthew Selby
Dr Stephen Crosier
Ben Skalkoyannis
Professor Simon Bailey
et al.
Characterising critical pathways in ATRT tumourigenesis: a genome-wide analysis of primary tumours and functional genomic models2014
Dr Janet Lindsey
Dr Ed Schwalbe
Dr James Hayden
Professor David Ellison
Dr Daniel Williamson
et al.
Cross-Species Epigenetics Identifies a Critial Role for VAV1 in the Maintenance of Sonic Hedgehog Subgroup Medulloblastomas2014
Dr Daniel Williamson
Professor Olaf Heidenreich
Identification of a Dynamic Core Transcriptional Network in t(8;21) AML that Regulates Differentiation Block and Self-Renewal2014
Dr Martina Finetti
Ben Skalkoyannis
Matthew Selby
Dr Stephen Crosier
Professor Simon Bailey
et al.
Mechanism of tumourigenesis caused by loss of SMARCB1 in malignant rhabdoid tumors2014
Professor Simon Bailey
Professor Steven Clifford
Dr Daniel Williamson
Medulloblastoma Down Under 2013: a report from the third annual meeting of the International Medulloblastoma Working Group2014
Dr Rebecca Hill
Dr Janet Lindsey
Dr Ed Schwalbe
Dr Daniel Williamson
Dr Sarra Ryan
et al.
MYC and TP53 defects emerge and interact at medulloblastoma relapse, define rapidly progressive disease and can be targeted therapeutically2014
Dr Rebecca Hill
Dr Janet Lindsey
Dr Ed Schwalbe
Dr Karen Barker
Dr Daniel Williamson
et al.
MYC and TP53 defects interact at medulloblastoma relapse to define rapidly progressive disease and can be targeted therapeutically2014
Dr Martina Finetti
Matthew Selby
Alicia Del Carpio Pons
Ben Skalkoyannis
Amanda Smith
et al.
Next-generation sequencing identifies the mechanism of tumourigenesis caused by loss of SMARCB1 in malignant rhabdoid tumours2014
Dr Ed Schwalbe
Dr Debbie Hicks
Dr Reza Rafiee
Dr Amir Enshaei
Sandeep Potluri
et al.
Routine molecular subgrouping of medulloblastoma: Bridging the divide between research and the clinic using low-cost DNA methylomics2014
Dr Klaus Rehe
Kerrie Wilson
Dr Simon Bomken
Dr Daniel Williamson
Professor Julie Irving
et al.
Acute B lymphoblastic leukaemia-propagating cells are present at high frequency in diverse lymphoblast populations2013
Dr Ed Schwalbe
Dr Daniel Williamson
Dr Janet Lindsey
Dolores Hamilton
Sarra Ryan
et al.
DNA methylation profiling of medulloblastoma allows robust subclassification and improved outcome prediction using formalin-fixed biopsies2013
Dr Daniel Williamson
HES6 enhances the motility of alveolar rhabdomyosarcoma cells2013
Dr Daniel Williamson
Professor Olaf Heidenreich
Identification of a Dynamic Core Transcriptional Regulatory Network for t(8;21) AML2013
Dr Matthew Allen
Dr Daniel Williamson
Professor Steven Clifford
Inhibiting Polo-like kinase 1 causes growth reduction and apoptosis in pediatric acute lymphoblastic leukemia cells2013
Dr Sarra Ryan
Dr Ed Schwalbe
Mike Cole
Yuan Lu
Dr Meryl Lusher
et al.
MYC family amplification and clinical risk-factors interact to predict an extremely poor prognosis in childhood medulloblastoma2012
Dr Daniel Williamson
PAX3/FOXO1 Fusion Gene Status is the Key Prognostic Molecular Marker in Rhabdomyosarcoma and Significantly Improves Current Risk Stratification2012
Dr Daniel Williamson
Professor Steven Clifford
A significant proportion of medulloblastoma do not sub-group robustly: Identification of a molecular NOS (not otherwise specified) subgroup2012
Dr Daniel Williamson
Professor Steven Clifford
Biological and clinical heterogeneity of MYCN-amplified medulloblastoma2012
Dr Daniel Williamson
Hesta McNeill
Dr Michael Cullen
Professor Bryan Young
Professor Olaf Heidenreich
et al.
Depletion of RUNX1/ETO in t(8;21) AML cells leads to genome-wide changes in chromatin structure and transcription factor binding2012
Dr Daniel Williamson
Professor Steven Clifford
Dissecting the genomic complexity underlying medulloblastoma2012
Dr Ed Schwalbe
Dr Janet Lindsey
Dr Daniel Williamson
Kieran O'Toole
Dr Meryl Lusher
et al.
Epigenetic sub-classification and risk-stratification of medulloblastoma using DNA methylomics2012
Dr Daniel Williamson
Inconvenience of Convenience Cohorts-Letter2012
Dr Daniel Williamson
Fusion Gene-Negative Alveolar Rhabdomyosarcoma Is Clinically and Molecularly Indistinguishable From Embryonal Rhabdomyosarcoma2010
Dr Daniel Williamson
Reply to J.R. Anderson et al2010
Dr Daniel Williamson
Genomic Imbalances in Rhabdomyosarcoma Cell Lines Affect Expression of Genes Frequently Altered in Primary Tumors: An Approach to Identify Candidate Genes Involved in Tumor Development2009
Dr Daniel Williamson
Role for amplification and expression of Glypican-5 in rhabdomyosarcoma2007
Dr Daniel Williamson
Comparative genomic hybridization and BUB1B mutation analyses in childhood cancers associated with mosaic variegated aneuploidy syndrome2006
Dr Daniel Williamson
Nascent pre-rRNA overexpression correlates with an adverse prognosis in alveolar rhabdomyosarcoma2006
Dr Daniel Williamson
Rapid and accurate determination of MYCN copy number and 1p deletion in neuroblastoma by quantitative PCR2006
Dr Daniel Williamson
The MET receptor tyrosine kinase contributes to invasive tumour growth in rhabdomyosarcomas2006
Dr Daniel Williamson
Relationship between MYCN copy number and expression in rhabdomyosarcomas and correlation with adverse prognosis in the alveolar subtype2005
Dr Daniel Williamson
Comparative genomic hybridisation and comparative expressed sequence hybridisation as complements to microarray analyses of tumours2004
Dr Daniel Williamson
Expression profiling targeting chromosomes for tumor classification and prediction of clinical behavior2003
Dr Daniel Williamson
Comparative expressed sequence hybridization to chromosomes for tumor classification and identification of genomic regions of differential gene expression2001