Publications by Dr Daniel Williamson - ePrints

Browsing publications by Dr Daniel Williamson.

Newcastle Authors	Title	Year
Dr Ed Schwalbe Dr Janet Lindsey Dr Marina Danilenko Dr Rebecca Hill Dr Stephen Crosier et al.	Molecular and clinical heterogeneity within MYC-family amplified medulloblastoma is associated with survival outcomes: A multicenter cohort study	2025
Dr Marion Mateos Dr Daniel Williamson Dr Marina Danilenko Dr Jack Goddard Dr Stephen Crosier et al.	MDB-64. Novel transcripts associate with survival in childhood medulloblastoma.	2024
Dr Florence Burté Magretta Adiamah Dr Fatma Scerif Dr Debbie Hicks Dr Ed Schwalbe et al.	Metabolite profiles of medulloblastoma for rapid and non-invasive detection of molecular disease groups	2024
James Hacking Dr Dean Thompson Dr Ed Schwalbe Professor Steven Clifford Dr Daniel Williamson et al.	Deriving a continuum score for group 3 and 4 medulloblastoma tumor samples analyzed via RNA-sequencing or DNA methylation microarray	2023
Dr Jack Goddard Jemma Castle Emily Southworth Anya Fletcher Dr Stephen Crosier et al.	Molecular characterisation defines clinically-actionable heterogeneity within Group 4 medulloblastoma and improves disease risk-stratification	2023
Dr Daniel Williamson	The proteomic landscape of soft tissue sarcomas	2023
Dr Daniel Williamson Dr Ed Schwalbe Professor Simon Bailey Professor Steven Clifford	Timing is everything: A connection between medulloblastoma prognosis and foetal cerebellar development	2023
Dr Daniel Williamson Professor Steven Clifford	Beta-blockers disrupt mitochondrial bioenergetics and increase radiotherapy efficacy independently of beta-adrenergic receptors in medulloblastoma	2022
Dr Stacey Richardson Dr Rebecca Hill Dr Christopher Kui Dr Janet Lindsey Dr Yura Grabovska et al.	Emergence and maintenance of actionable genetic drivers at medulloblastoma relapse	2022
Dr Ricky Tirtakusuma Dr Katarzyna Szoltysek Professor Vasily Grinev Dr Sirintra Nakjang Dr Daniel Williamson et al.	Epigenetic regulator genes direct lineage switching in MLL/AF4 leukemia	2022
Dr Yura Grabovska Dr Daniel Williamson	Erratum: Molecular subgrouping of atypical teratoid/rhabdoid tumors - a reinvestigation and current consensus (Neuro-Oncology DOI: 10.1093/neuonc/noz235)	2022
Dr Jack Goddard Jemma Castle Emily Southworth Anya Fletcher Dr Stephen Crosier et al.	MEDB-71. Molecular characterisation of Group 4 medulloblastoma improves risk-stratification and its biological understanding	2022
Dr Daniel Williamson Dr Ed Schwalbe Dr Debbie Hicks Dr Janet Lindsey Dr Stephen Crosier et al.	Medulloblastoma group 3 and 4 tumors comprise a clinically and biologically significant expression continuum reflecting human cerebellar development	2022
Dr Marina Danilenko Dr Claire Keeling Dr Stephen Crosier Dr Martina Finetti Dr Daniel Williamson et al.	Single-cell DNA sequencing identifies risk-associated clonal complexity and evolutionary trajectories in childhood medulloblastoma development	2022
Dr Stephen Crosier Dr Debbie Hicks Dr Ed Schwalbe Dr Daniel Williamson Amanda Smith et al.	Advanced molecular pathology for rare tumours: A national feasibility study and model for centralised medulloblastoma diagnostics	2021
Dr Debbie Hicks Dr Reza Rafiee Dr Ed Schwalbe Dr Christopher Howell Dr Janet Lindsey et al.	The molecular landscape and associated clinical experience in infant medulloblastoma: prognostic significance of second-generation subtypes	2021
Dr Matthew Selby Dr Daniel Williamson Professor Steven Clifford	Erratum: Author Correction: VEGFC negatively regulates the growth and aggressiveness of medulloblastoma cells (Communications biology (2020) 3 1 (579))	2020
Dr Martina Finetti Dr Daniel Williamson	Locoregionally administered B7-H3-targeted CAR T cells for treatment of atypical teratoid/rhabdoid tumors	2020
Yura Grabovska Dr Daniel Williamson	Molecular subgrouping of Atypical Teratoid/Rhabdoid Tumors (ATRT) – a reinvestigation and current consensus	2020
Dr Yura Grabovska Dr Stephen Crosier Dr Martina Finetti Dr Ed Schwalbe Dr Rebecca Hill et al.	Pediatric pan-central nervous system tumor analysis of immune-cell infiltration identifies correlates of antitumor immunity	2020
Dr Rebecca Hill Dr Stacey Richardson Dr Ed Schwalbe Dr Debbie Hicks Dr Janet Lindsey et al.	Time, pattern, and outcome of medulloblastoma relapse and their association with tumour biology at diagnosis and therapy: a multicentre cohort study	2020
Dr Martina Finetti Yura Grabovska Professor Simon Bailey Dr Daniel Williamson	Translational Genomics of Malignant Rhabdoid Tumours: Current Impact and Future Possibilities	2020
Dr Martina Finetti Dr Daniel Williamson	Comprehensive Analysis of Chromatin States in Atypical Teratoid/Rhabdoid Tumor Identifies Diverging Roles for SWI/SNF and Polycomb in Gene Regulation	2019
Dr Rebecca Hill Professor Steven Clifford Yura Grabovska Dr Daniel Williamson	DNA methylation-based profiling for paediatric CNS tumour diagnosis and treatment: a population-based study	2019
Dr Ed Schwalbe Dr Daniel Williamson Dr Janet Lindsey Dr Rebecca Hill Dr Debbie Hicks et al.	Second-generation molecular subgrouping of medulloblastoma: an international meta-analysis of Group 3 and Group 4 subtypes	2019
Dr Daniel Williamson Dr Christopher Jones Professor Steven Clifford	Biological material collection to advance translational research and treatment of children with CNS tumours: position paper from the SIOPE Brain Tumour Group	2018
Dr Ed Schwalbe Dr Debbie Hicks Dr Reza Rafiee Dr Matthew Bashton Dr Amir Enshaei et al.	Minimal methylation classifier (MIMIC): A novel method for derivation and rapid diagnostic detection of disease-associated DNA methylation signatures	2017
Dr Ed Schwalbe Dr Janet Lindsey Dr Sirintra Nakjang Dr Stephen Crosier Amanda Smith et al.	Novel molecular subgroups for clinical classification and outcome prediction in childhood medulloblastoma: a cohort study	2017
Dr Matthew Selby Dr Daniel Williamson Professor Steven Clifford	TAp73 is a marker of glutamine addiction in medulloblastoma	2017
Dr Stephen Crosier Dr Debbie Hicks Dr Ed Schwalbe Dr Daniel Williamson Sarah Nicholson et al.	Centralised Molecular Pathology for Rare Tumours: A National Feasibility Study of Real-Time Medulloblastoma Diagnostics	2016
Dr Al Gabriel Dr Lindi Chen Dr Sirintra Nakjang Dr Daniel Williamson Professor Deborah Tweddle et al.	Combined Copy Number and Gene Expression Profiling in High Rick Neuroblastoma: A CCLG Pilot Biological Study	2016
Dr Martina Finetti Dr Stephen Crosier Dr Daniel Williamson	Dual Targeting of PDGFR alpha and FGFR1 Displays Synergistic Efficacy in Malignant Rhabdoid Tumors	2016
Dr Debbie Hicks Dr Ed Schwalbe Dr Stephen Crosier Professor Simon Bailey Dr Daniel Williamson et al.	Identification of medulloblastoma molecular subgroups using metabolite profiles	2016
Dr Martina Finetti Matthew Selby Dr Matthew Bashton Dr Ruth Cranston Dr Stephen Crosier et al.	Integrated pathway analysis of malignant rhabdoid tumour identifies key SMARCB1-pathways and therapeutic opportunities	2016
Dr Martina Finetti Alicia Del Carpio Pons James Barker James Wood Dr Sirintra Nakjang et al.	Integrated pathway analysis of rhabdoid tumor subtypes identifies key SMARCB1-dependencies and therapeutic opportunities	2016
Matthew Selby Dr Martina Finetti Dr Matthew Bashton Dr Ruth Cranston Alicia Del Carpio Pons et al.	Investigating the biology of atypical teratoid/rhabdoid tumors by whole genome CRISPR/CAS9 screening	2016
Dr Janet Lindsey Dr Rebecca Hill Dr Ed Schwalbe Dr Christopher Howell Dr Reza Rafiee et al.	Molecular and Prognostic Heterogeneity within MYC and MYCN Amplified Medulloblastomas	2016
Dr Ed Schwalbe Dr Debbie Hicks Dr Reza Rafiee Dr Matthew Bashton Dr Amir Enshaei et al.	Routine Diagnostic Medulloblastoma Subgrouping Using Low-Cost, Low-Input DNA Methylomics: Application to Trials Cohorts Previously Refractory-to-Analysis	2016
Dr Ed Schwalbe Dr Debbie Hicks Dr Reza Rafiee Dr Matthew Bashton Dr Amir Enshaei et al.	Routine molecular subgrouping of medulloblastoma: Bridging the divide between research and the clinic using low-cost, mass spectrometry-based DNA methylomics	2016
Dr Debbie Hicks Dr Reza Rafiee Dr Ed Schwalbe Dr Christopher Howell Dr Janet Lindsey et al.	Subgroup-Directed Stratification of Risk in Infant Medulloblastoma	2016
Dr Daniel Williamson Dr Janet Lindsey Dr Debbie Hicks Dr Stephen Crosier Amanda Smith et al.	The Transcriptional Landscape of Medulloblastoma: Group 3 and Group 4 Tumours Comprise a Single Clinically Significant Expression Continuum	2016
Dr Rebecca Hill Dr Janet Lindsey Dr Ed Schwalbe Dr Karen Barker Dr Daniel Williamson et al.	Combined MYC and P53 Defects Emerge at Medulloblastoma Relapse and Define Rapidly Progressive, Therapeutically Targetable Disease	2015
Dr Janet Lindsey Dr Ed Schwalbe Matthew Selby Dr James Hayden Dr Daniel Williamson et al.	Cross-species epigenetics identifies a critical role for VAV1 in SHH subgroup medulloblastoma maintenance	2015
Dr Lindsay Nicholson Elizabeth Matheson Lynne Minto Christopher Keilty Maryna Sanichar et al.	Quantitative proteomic analysis reveals maturation as a mechanism underlying glucocorticoid resistance in B lineage ALL and re-sensitization by JNK inhibition	2015
Dr Janet Lindsey Dr Ed Schwalbe Sandeep Potluri Professor Simon Bailey Dr Daniel Williamson et al.	TERT promoter mutation and aberrant hypermethylation are associated with elevated expression in medulloblastoma and characterise the majority of non-infant SHH subgroup tumours	2014
Dr Martina Finetti Alicia Del Carpio Pons Ben Skalkoyannis Matthew Selby Amanda Smith et al.	A Systems Biology Approach to Identify Mechanism of Tumourigenesis Caused by Loss of SMARCB1 in Malignant Rhabdoid Tumors (BACR28)	2014
Dr Martina Finetti Matthew Selby Dr Stephen Crosier Ben Skalkoyannis Professor Simon Bailey et al.	Characterising critical pathways in ATRT tumourigenesis: a genome-wide analysis of primary tumours and functional genomic models	2014
Dr Janet Lindsey Dr Ed Schwalbe Dr James Hayden Professor David Ellison Dr Daniel Williamson et al.	Cross-Species Epigenetics Identifies a Critial Role for VAV1 in the Maintenance of Sonic Hedgehog Subgroup Medulloblastomas	2014
Dr Daniel Williamson Professor Olaf Heidenreich	Identification of a Dynamic Core Transcriptional Network in t(8;21) AML that Regulates Differentiation Block and Self-Renewal	2014
Dr Martina Finetti Ben Skalkoyannis Matthew Selby Dr Stephen Crosier Professor Simon Bailey et al.	Mechanism of tumourigenesis caused by loss of SMARCB1 in malignant rhabdoid tumors	2014
Professor Simon Bailey Professor Steven Clifford Dr Daniel Williamson	Medulloblastoma Down Under 2013: a report from the third annual meeting of the International Medulloblastoma Working Group	2014
Dr Rebecca Hill Dr Janet Lindsey Dr Ed Schwalbe Dr Daniel Williamson Dr Sarra Ryan et al.	MYC and TP53 defects emerge and interact at medulloblastoma relapse, define rapidly progressive disease and can be targeted therapeutically	2014
Dr Rebecca Hill Dr Janet Lindsey Dr Ed Schwalbe Dr Karen Barker Dr Daniel Williamson et al.	MYC and TP53 defects interact at medulloblastoma relapse to define rapidly progressive disease and can be targeted therapeutically	2014
Dr Martina Finetti Matthew Selby Alicia Del Carpio Pons Ben Skalkoyannis Amanda Smith et al.	Next-generation sequencing identifies the mechanism of tumourigenesis caused by loss of SMARCB1 in malignant rhabdoid tumours	2014
Dr Ed Schwalbe Dr Debbie Hicks Dr Reza Rafiee Dr Amir Enshaei Sandeep Potluri et al.	Routine molecular subgrouping of medulloblastoma: Bridging the divide between research and the clinic using low-cost DNA methylomics	2014
Dr Klaus Rehe Kerrie Wilson Dr Simon Bomken Dr Daniel Williamson Professor Julie Irving et al.	Acute B lymphoblastic leukaemia-propagating cells are present at high frequency in diverse lymphoblast populations	2013
Dr Ed Schwalbe Dr Daniel Williamson Dr Janet Lindsey Dolores Hamilton Sarra Ryan et al.	DNA methylation profiling of medulloblastoma allows robust subclassification and improved outcome prediction using formalin-fixed biopsies	2013
Dr Daniel Williamson	HES6 enhances the motility of alveolar rhabdomyosarcoma cells	2013
Dr Daniel Williamson Professor Olaf Heidenreich	Identification of a Dynamic Core Transcriptional Regulatory Network for t(8;21) AML	2013
Dr Matthew Allen Dr Daniel Williamson Professor Steven Clifford	Inhibiting Polo-like kinase 1 causes growth reduction and apoptosis in pediatric acute lymphoblastic leukemia cells	2013
Dr Sarra Ryan Dr Ed Schwalbe Mike Cole Yuan Lu Dr Meryl Lusher et al.	MYC family amplification and clinical risk-factors interact to predict an extremely poor prognosis in childhood medulloblastoma	2012
Dr Daniel Williamson	PAX3/FOXO1 Fusion Gene Status is the Key Prognostic Molecular Marker in Rhabdomyosarcoma and Significantly Improves Current Risk Stratification	2012
Dr Daniel Williamson Professor Steven Clifford	A significant proportion of medulloblastoma do not sub-group robustly: Identification of a molecular NOS (not otherwise specified) subgroup	2012
Dr Daniel Williamson Professor Steven Clifford	Biological and clinical heterogeneity of MYCN-amplified medulloblastoma	2012
Dr Daniel Williamson Hesta McNeill Dr Michael Cullen Professor Bryan Young Professor Olaf Heidenreich et al.	Depletion of RUNX1/ETO in t(8;21) AML cells leads to genome-wide changes in chromatin structure and transcription factor binding	2012
Dr Daniel Williamson Professor Steven Clifford	Dissecting the genomic complexity underlying medulloblastoma	2012
Dr Ed Schwalbe Dr Janet Lindsey Dr Daniel Williamson Kieran O'Toole Dr Meryl Lusher et al.	Epigenetic sub-classification and risk-stratification of medulloblastoma using DNA methylomics	2012
Dr Daniel Williamson	Inconvenience of Convenience Cohorts-Letter	2012
Dr Daniel Williamson	Fusion Gene-Negative Alveolar Rhabdomyosarcoma Is Clinically and Molecularly Indistinguishable From Embryonal Rhabdomyosarcoma	2010
Dr Daniel Williamson	Reply to J.R. Anderson et al	2010
Dr Daniel Williamson	Genomic Imbalances in Rhabdomyosarcoma Cell Lines Affect Expression of Genes Frequently Altered in Primary Tumors: An Approach to Identify Candidate Genes Involved in Tumor Development	2009
Dr Daniel Williamson	Role for amplification and expression of Glypican-5 in rhabdomyosarcoma	2007
Dr Daniel Williamson	Comparative genomic hybridization and BUB1B mutation analyses in childhood cancers associated with mosaic variegated aneuploidy syndrome	2006
Dr Daniel Williamson	Nascent pre-rRNA overexpression correlates with an adverse prognosis in alveolar rhabdomyosarcoma	2006
Dr Daniel Williamson	Rapid and accurate determination of MYCN copy number and 1p deletion in neuroblastoma by quantitative PCR	2006
Dr Daniel Williamson	The MET receptor tyrosine kinase contributes to invasive tumour growth in rhabdomyosarcomas	2006
Dr Daniel Williamson	Relationship between MYCN copy number and expression in rhabdomyosarcomas and correlation with adverse prognosis in the alveolar subtype	2005
Dr Daniel Williamson	Comparative genomic hybridisation and comparative expressed sequence hybridisation as complements to microarray analyses of tumours	2004
Dr Daniel Williamson	Expression profiling targeting chromosomes for tumor classification and prediction of clinical behavior	2003
Dr Daniel Williamson	Comparative expressed sequence hybridization to chromosomes for tumor classification and identification of genomic regions of differential gene expression	2001