Erhan Aptullahoglu Dr Sirintra Nakjang Dr Jonathan Wallis Dr Helen Marr Dr Scott Marshall et al. | RNA Sequencing Reveals Candidate Genes and Pathways Associated with Resistance to MDM2 Antagonist Idasanutlin in TP53 Wild-Type Chronic Lymphocytic Leukemia | 2024 |
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Zainab Alebady Dr Mahsa Azizyan Dr Sirintra Nakjang Dr Emma Lishman-Walker Jesslyn Choo et al. | CDC20 is regulated by the histone methyltransferase, KMT5A, in castration resistant prostate cancer | 2023 |
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Chalermsin Permtermsin - Lalchungnunga Dr Sirintra Nakjang John Casement Dr Laura Ogle et al. | Identification of TIAM1 as a Potential Synthetic-Lethal-like Gene in a Defined Subset of Hepatocellular Carcinoma | 2023 |
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Dr Ricky Tirtakusuma Dr Katarzyna Szoltysek Professor Vasily Grinev Dr Sirintra Nakjang Dr Daniel Williamson et al. | Epigenetic regulator genes direct lineage switching in MLL/AF4 leukemia | 2022 |
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Dr Deepali Pal Dr Helen Blair Sean Hockney Dr Melanie Beckett Mankaran Singh et al. | hiPSC-derived bone marrow milieu identifies a clinically actionable driver of niche-mediated treatment resistance in leukemia | 2022 |
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Dr Timothy Barrow Dr Sirintra Nakjang Kateryna Bilotkach Dr Laura Woodhouse Gesa Junge et al. | Epigenome-wide analysis reveals functional modulators of drug sensitivity and post-treatment survival in chronic lymphocytic leukaemia | 2021 |
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Marco Zaki Dr Ahmed Mahdi Dr Gillian Patman Anna Whitehead Joao Mauricio et al. | Key features of the environment promoting liver cancer in the absence of cirrhosis | 2021 |
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Yuzhe Shi Melanie Beckett Dr Helen Blair Dr Ricky Tirtakusuma Dr Sirintra Nakjang et al. | Phase II-like murine trial identifies synergy between dexamethasone and dasatinib in T-cell acute lymphoblastic leukemia | 2021 |
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Professor Vasily Grinev Dr Sirintra Nakjang Hesta McNeill Dr Mojgan Reza Dr Natalia Martinez Soria et al. | RUNX1/RUNX1T1 mediates alternative splicing and reorganises the transcriptional landscape in leukemia | 2021 |
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Dr Amir Enshaei Dr Sirintra Nakjang Lynne Minto Professor Julie Irving Beth Poole et al. | The genomic landscape of teenage and young adult T-cell acute lymphoblastic leukemia | 2021 |
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Evangelia Kounatidou Dr Sirintra Nakjang Dr Stuart McCracken Professor Craig Robson Dr Dominic Jones et al. | A novel CRISPR-engineered prostate cancer cell line defines the AR-V transcriptome and identifies PARP inhibitor sensitivities | 2019 |
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Matthew Simcock Dr Sirintra Nakjang Dr Richard Heath Dr Lauren Walker Dr Craig Robson et al. | The Pioneering Role of GATA2 in Androgen Receptor Variant Regulation Is Controlled by Bromodomain and Extraterminal Proteins in Castrate-Resistant Prostate Cancer | 2019 |
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Dr Peixun Zhou Dr Amir Enshaei Alex Newman Dr Amy Erhorn Amy Barnard et al. | A genomic classification model enables risk stratification of paediatric endemic Burkitt lymphoma | 2018 |
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James Grey Dr Dominic Jones Laura Wilson Dr Sirintra Nakjang Jake Clayton et al. | Differential regulation of the androgen receptor by protein phosphatase regulatory subunits | 2018 |
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Dr Urszula McClurg Dr Mahsa Azizyan Dr Sirintra Nakjang Dr Stuart McCracken Professor Craig Robson et al. | Molecular mechanism of the TP53-MDM2-AR-AKT signalling network regulation by USP12 | 2018 |
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Dr Urszula McClurg Dr Mahsa Azizyan Dr Sirintra Nakjang Professor Craig Robson
| The novel anti-androgen candidate galeterone targets deubiquitinating enzymes, USP12 and USP46, to control prostate cancer growth and survival | 2018 |
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Dr Lynsey McKenzie Hasan Issa Sandeep Potluri Dr Helen Blair Asmida Isa et al. | The Oncogenic Transcription Factor RUNX1/ETO Corrupts Cell Cycle Regulation to Drive Leukemic Transformation | 2018 |
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Dr Paul Dean Dr Kacper Sendra Dr Tom Williams Andrew Watson Dr Peter Major et al. | Transporter gene acquisition and innovation in the evolution of Microsporidia intracellular parasites | 2018 |
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Dr Alina Goldberg Cavalleri Dr Paul Dean Dr Tom Williams Dr Sirintra Nakjang Dr Shaojun Long et al. | Evolutionary conservation and in vitro reconstitution of microsporidian iron–sulfur cluster biosynthesis | 2017 |
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Dr Urszula McClurg Dr David Cork Dr Steven Darby Claudia Ryan-Munden Dr Sirintra Nakjang et al. | Identification of a novel K311 ubiquitination site critical for androgen receptor transcriptional activity | 2017 |
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Dr Richard Noble Dr Natalie Bell Dr Helen Blair Huw Thomas Nicole Phillips et al. | Inhibition of monocarboxyate transporter 1 by AZD3965 as a novel therapeutic approach for diffuse large B-cell lymphoma and burkitt lymphoma | 2017 |
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Dr Ed Schwalbe Dr Janet Lindsey Dr Sirintra Nakjang Dr Stephen Crosier Amanda Smith et al. | Novel molecular subgroups for clinical classification and outcome prediction in childhood medulloblastoma: a cohort study | 2017 |
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Dr Urszula McClurg Dr Sirintra Nakjang Dr Stuart McCracken Professor Craig Robson
| A novel anti-androgen candidate galeterone acts by targeting USP12, a deubiquitinating enzyme that controls prostate cancer growth and survival | 2016 |
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Dr Tom Williams Dr Sirintra Nakjang Professor Robert Hirt Emeritus Professor T. Martin Embley FMedSci FRS
| A Recent Whole-Genome Duplication Divides Populations of a Globally Distributed Microsporidian | 2016 |
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Dr Lisa Russell Lisa Jones Dr Amir Enshaei Dr Stefano Tonin Sarra Ryan et al. | Characterisation of the genomic landscape of CRLF2-rearranged acute lymphoblastic leukemia | 2016 |
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Arman Esfandiari Dr Sirintra Nakjang Professor John Lunec
| Chemical Inhibition of Wild-Type p53-Induced Phosphatase 1 (WIP1/PPM1D) by GSK2830371 Potentiates the Sensitivity to MDM2 Inhibitors in a p53-Dependent Manner | 2016 |
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Dr Al Gabriel Dr Lindi Chen Dr Sirintra Nakjang Dr Daniel Williamson Professor Deborah Tweddle et al. | Combined Copy Number and Gene Expression Profiling in High Rick Neuroblastoma: A CCLG Pilot Biological Study | 2016 |
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Dr Lynsey McKenzie Dr Sirintra Nakjang Dr Helen Blair Professor Hermann Josef Vormoor Professor Olaf Heidenreich et al. | Identification of CCND2 As a RUNX1/ETO Target Required for Leukaemic Propagation | 2016 |
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Dr Martina Finetti Alicia Del Carpio Pons James Barker James Wood Dr Sirintra Nakjang et al. | Integrated pathway analysis of rhabdoid tumor subtypes identifies key SMARCB1-dependencies and therapeutic opportunities | 2016 |
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Dr Paul Sinclair Joanna Cheng Prahlad Raninga Rebecca Hanna Shaun Hollern et al. | A Targeted Functional Clone Tracking Assay for the Identification of Tumour Suppressor Genes in BCP- ALL Implicates the Transcription Factors FOXO3 and PRDM1 | 2015 |
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Dominic Jones Dr Mark Wade Jim Grey Dr Sirintra Nakjang Wenrui Guo et al. | Development and exploitation of a novel mutant androgen receptor modelling strategy to identify new targets for advanced prostate cancer therapy | 2015 |
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Dr Al Gabriel Fadhel Alsaid Naji Dr Ed Schwalbe Dr Sirintra Nakjang Dr Simon Cockell et al. | Epigenetic landscape correlates with genetic subtype but does not predict outcome in childhood acute lymphoblastic leukemia | 2015 |
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Dr Aiste McCormick Dr Sirintra Nakjang Dr Peter Donoghue Professor Nicola Curtin Professor Richard Edmondson et al. | The role of homologous recombination recovery in cisplatin and rucaparib resistance in ovarian cancer | 2015 |
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Dr Keith Flanagan Dr Simon Cockell Professor Colin Harwood Dr Jennifer Hallinan Dr Sirintra Nakjang et al. | A distributed computational search strategy for the identification of diagnostics targets: Application to finding aptamer targets for methicillin-resistant staphylococci | 2014 |
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Dr Jeyanthy Eswaran Dr Paul Sinclair Dr Sirintra Nakjang Professor Christine Harrison FRCPath FMedSci
| Identification of Cmtm Family Proteins As Tumor Suppressor and Membrane Regulator in B Cell Precursor Acute Lymphoblastic Leukemia | 2014 |
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Dr Eva Heinz Dr Paul Dean Dr Alina Goldberg Cavalleri Dr Sirintra Nakjang Dr Alison Gregory et al. | Plasma Membrane-Located Purine Nucleotide Transport Proteins are Key Components for Host Exploitation by Microsporidian Intracellular Parasites | 2014 |
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Dr Paul Dean Dr Peter Major Dr Sirintra Nakjang Professor Robert Hirt Emeritus Professor T. Martin Embley FMedSci FRS et al. | Transport proteins of parasitic protists and their role in nutrient salvage | 2014 |
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Dr Cecilia Alsmark Dr Sirintra Nakjang Emeritus Professor T. Martin Embley FMedSci FRS Professor Robert Hirt
| Patterns of prokaryotic lateral gene transfers affecting parasitic microbial eukaryotes | 2013 |
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Dr Sirintra Nakjang Dr Tom Williams Dr Eva Heinz Andrew Watson Dr Peter Foster et al. | Reduction and Expansion in Microsporidian Genome Evolution: New Insights from Comparative Genomics | 2013 |
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Dr Sirintra Nakjang Dr Didier Ndeh Professor Anil Wipat Dr David Bolam Professor Robert Hirt et al. | A Novel Extracellular Metallopeptidase Domain Shared by Animal Host-Associated Mutualistic and Pathogenic Microbes | 2012 |
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Matt Collison Professor Robert Hirt Professor Anil Wipat Dr Sirintra Nakjang
| Data mining the human gut microbiota for therapeutic targets | 2012 |
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Dr Keith Flanagan Dr Sirintra Nakjang Dr Jennifer Hallinan Professor Colin Harwood Professor Robert Hirt et al. | Microbase2.0: a generic framework for computationally intensive bioinformatics workflows in the cloud | 2012 |
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Dr Eva Heinz Dr Tom Williams Dr Sirintra Nakjang Dr Christophe Noel Dr Daniel Swan et al. | The Genome of the Obligate Intracellular ParasiteTrachipleistophora hominis: New Insights into Microsporidian Genome Dynamics and Reductive Evolution | 2012 |
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Professor Robert Hirt Dr Sirintra Nakjang
| Trichomonas vaginalis Pathobiology: New Insights from the Genome Sequence | 2011 |
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Dr Sirintra Nakjang Professor Robert Hirt Professor Anil Wipat
| Automatic extraction of microorganisms and their habitats from free text using text mining workflows | 2011 |
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