Dr Benoit Carbain Dr Allyson Campbell Dr Celine Cano Professor Jane Endicott Emeritus Professor Bernard Golding et al. | 8-Substituted O-6-Cyclohexylmethylguanine CDK2 Inhibitors: Using Structure-Based Inhibitor Design to Optimize an Alternative Binding Mode | 2014 |
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Dr Kelly Coffey Dr Tim Blackburn Susan Cook Emeritus Professor Bernard Golding Professor Roger Griffin et al. | Characterisation of a Tip60 specific inhibitor, NU9056, in prostate cancer | 2012 |
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Huw Thomas Dr Celine Roche Dr Johanne Bentley Dr Ian Hardcastle Emeritus Professor Bernard Golding et al. | Preclinical in vitro and in vivo evaluation of the potent and specific cyclin-dependent kinase 2 inhibitor NU6102 and a water soluble prodrug NU6301 | 2011 |
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Dr Benoit Carbain Dr Celine Roche Emeritus Professor Bernard Golding Dr Ian Hardcastle Dr Celine Cano et al. | Structure-based design of C8-substituted O6-alkylguanine CDK1 and 2 inhibitors | 2010 |
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Dr Celine Roche Professor Steve Wedge Professor Herbie Newell Dr Michael Tilby
| The kinase inhibitor O6-cyclohexylmethylguanine (NU2058) potentiates the cytotoxicity of cisplatin by mechanisms that are independent of its effect upon CDK2 | 2009 |
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Professor Herbie Newell Huw Thomas Lan Wang Dr Celine Roche Dr Ian Hardcastle et al. | [abstract] Preclinical in vitro and in vivo evaluation of the cyclin dependent kinase 2 inhibitor NU6102 and a water pro-drug NU6301 | 2008 |
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