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Browsing publications by Dr Lee Borthwick

Newcastle AuthorsTitleYearFull text
Dr Lee Borthwick
Advances in Extracellular Matrix-Associated Diagnostics and Therapeutics2025
Dr Teresa Borrello
Dr Hannah Paish
Eleanor Graham
Amy Collins
Dr Sam Higginbotham
et al.
Pharmacological manipulation of liver fibrosis progression using novel HDAC6 inhibitors2025
Amy Collins
Keara Kirkness
Erik Ramon Gil
Eleni Tzortzopoulou
Daniel Geh
et al.
Precision-cut tumor slices for modeling hepatocellular carcinoma enable at-scale drug screening2025
Bethany Hunter
Rachel Burgoyne
Dr Lee Borthwick
Professor James Shaw
Professor Andrew Filby
et al.
Temporo-spatial cellular atlas of the regenerating alveolar niche in idiopathic pulmonary fibrosis2025
Dr Lee Borthwick
Defining the mechanism of galectin-3–mediated TGF-β1 activation and its role in lung fibrosis2024
Lucy Gee
Amy Collins
Lee Reed
Dr Lee Borthwick
Dr Christopher Morris
et al.
Hepatocellular senescence induces multi-organ senescence and dysfunction via TGFβ2024
Lucy Gee
Dr Ben Barron-Millar
Dr Marco Zaki
Dr Saimir Luli
Rachel Burgoyne
et al.
Anti–Cholestatic Therapy with Obeticholic Acid Improves Short-Term Memory in Bile Duct–Ligated Mice2023
Professor Andrew Fisher
Dr Lee Borthwick
Identification of a broadly fibrogenic macrophage subset induced by type 3 inflammation2023
Laura Sabater
Jean-Baptiste Gossart
Inmaculada Hernandez Lopez
Dr Daniel Rico Rodriguez
Dr Lee Borthwick
et al.
miRNA Expression in Fibroblastic Foci within Idiopathic Pulmonary Fibrosis Lungs Reveals Novel Disease-Relevant Pathways2023
Tom Pither
Dr Lu Wang
Lucy Bates
Dr Morvern Morrison
Catriona Charlton
et al.
Modeling the Effects of IL-1β-mediated Inflammation During Ex Vivo Lung Perfusion Using a Split Human Donor Model2023
Dr Lee Borthwick
Professor Andrew Fisher
Altered Differentiation and Inflammation Profiles Contribute to Enhanced Innate Responses in Severe COPD Epithelium to Rhinovirus Infection2022
Dr Marco Zaki
Dr Sari Alhasan
Dr Ruchi Shukla
Misti McCain
Maja Laszczewska
et al.
Sulfatase-2 from Cancer Associated Fibroblasts: An Environmental Target for Hepatocellular Carcinoma?2022
Dr Morvern Morrison
Dr Anders Andreasson
Catriona Charlton
Dr Alisha Chhatwal
Dr Bill Scott
et al.
Transcriptional analysis identifies potential novel biomarkers associated with successful ex-vivo perfusion of human donor lungs2022
Dr Jack Leslie
Dr Hannah Paish
Amy Collins
Rebecca Scott
Abi Watson
et al.
A Mammalian Target of Rapamycin-Perilipin 3 (mTORC1-Plin3) Pathway is essential to Activate Lipophagy and Protects Against Hepatosteatosis2021
JinHeng Lin
Emeritus Professor Michael Taggart
Dr Lee Borthwick
Professor Andrew Fisher
Dr Malcolm Brodlie
et al.
Acute cigarette smoke or extract exposure rapidly activates TRPA1-mediated calcium influx in primary human airway smooth muscle cells2021
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