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Browsing publications by Dr James Garnett.

Newcastle AuthorsTitleYearFull text
Dr James Garnett
An EZH2-dependent transcriptional complex promotes aberrant epithelial remodelling after injury2021
Catherine Hatton
Dr Rachel Botting
Dr Maria Duenas Fadic
Dr Iram Haq
Dr Bernard Verdon
et al.
Delayed induction of type I and III interferons mediates nasal epithelial cell permissiveness to SARS-CoV-22021
Dr Emily Mavin
Dr Bernard Verdon
Sean Carrie
Dr Vinciane Saint-Criq
Jason Powell
et al.
Real-time measurement of cellular bioenergetics in fully differentiated human nasal epithelial 2 cells grown at air-liquid-interface2020
Dr James Garnett
Recapitulating idiopathic pulmonary fibrosis related alveolar epithelial dysfunction in a human iPSC‐derived air‐liquid interface model2020
Dr James Garnett
Effective glucose metabolism maintains low intracellular glucose in airway epithelial cells after exposure to hyperglycemia2019
Jason Powell
Dr James Garnett
Dr Michael Mather
Dr Faye Cooles
Dr Bernard Verdon
et al.
Excess Mucin Impairs Subglottic Epithelial Host Defense in Mechanically Ventilated Patients2018
Dr James Garnett
Metformin attenuates the effect of Staphylococcus aureus on airway tight junctions by increasing PKCζ-mediated phosphorylation of occludin2018
Salam Ibrahim
Mark Turner
Dr Vinciane Saint-Criq
Dr James Garnett
Dr Iram Haq
et al.
CK2 is a key regulator of SLC4A2- mediated Cl-/HCO3- exchange in human airway epithelia2017
Dr Iram Haq
Dr Michael Gray
Dr James Garnett
Professor Christopher Ward
Dr Malcolm Brodlie
et al.
Airway surface liquid homeostasis in cystic fibrosis: pathophysiology and therapeutic targets2016
Mark Turner
Dr Vinciane Saint-Criq
Waseema Patel
Salam Ibrahim
Dr Burns Verdon
et al.
Hypercapnia Modulates cAMP Signalling and Cystic Fibrosis Transmembrane Conductance Regulator-dependent Anion and Fluid Secretion in Airway Epithelia2016
Dr James Garnett
Dr Georgina Carr
Jason Powell
Dr Malcolm Brodlie
Professor Christopher Ward
et al.
Hyperglycaemia and Pseudomonas aeruginosa acidify cystic fibrosis airway surface liquid by elevating epithelial monocarboxylate transporter 2 dependent lactate-H+ secretion2016
Dr James Garnett
Increased airway glucose increases airway bacterial load in hyperglycaemia2016
Dr Georgina Carr
Dr James Garnett
Metformin prevents the effects of Pseudomonas aeruginosa on airway epithelial tight junctions and restricts hyperglycaemia-induced bacterial growth2016
Jason Powell
Dr James Garnett
Dr Bernard Verdon
Emerita Professor Janet Wilson
Professor Jeffrey Pearson
et al.
A Human in Vitro Model of the Subglottic Airway2015
Dr James Garnett
Dr Michael Gray
Dr Malcolm Brodlie
Professor Christopher Ward
Airway epithelial cells secrete bicarbonate in response to acidic by-products of pseudomonas aeruginosa metabolism2015
Dr James Garnett
A novel fluorescent sensor protein for detecting changes in airway surface liquid glucose concentration2014
Dr James Garnett
Fructose transport-deficient Staphylococcus aureus reveals important role of epithelial glucose transporters in limiting sugar-driven bacterial growth in airway surface liquid2014
Dr James Garnett
SPLUNC1: link between acidity and dehydration of the airway surface liquid in CF2014
Dr James Garnett
Mark Turner
Controversies surrounding the role of CFTR in airway bicarbonate secretion2013
Dr James Garnett
Dr Michael Gray
Dr Malcolm Brodlie
Professor Christopher Ward
Erin Baker
et al.
Elevated Paracellular Glucose Flux across Cystic Fibrosis Airway Epithelial Monolayers Is an Important Factor for Pseudomonas aeruginosa Growth2013
Dr James Garnett
Metformin reduces airway glucose permeability and hyperglycaemia-induced Staphylococcus aureus load independently of effects on blood glucose2013
Dr James Garnett
Hui Tunkamnerdthai
Dr Michael Gray
Protein phosphatase 1 coordinates CFTR-dependent airway epithelial HCO3- secretion by reciprocal regulation of apical and basolateral membrane Cl--HCO3- exchangers2013
Dr James Garnett
Erin Baker
Proinflammatory mediators disrupt glucose homeostasis in airway surface liquid2012
Dr James Garnett
Erin Baker
Sweet talk: insights into the nature and importance of glucose transport in lung epithelium2012
Dr James Garnett
Dr Michael Gray
Novel Role for Pendrin in Orchestrating Bicarbonate Secretion in Cystic Fibrosis Transmembrane Conductance Regulator (CFTR)-expressing Airway Serous Cells2011
Dr Simon Peacock
Dr Robert Shiel
Dr James Garnett
Ecological mechanisms affecting the restoration of diversity in agriculturally improved meadow grassland. Colonisation of plant roots by arbuscular mycorrhizas in upland meadow grasslands:correlations with management and plant phosphorus status2001