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Browsing publications by Dr Michael Gray.

Newcastle AuthorsTitleYearFull text
JinHeng Lin
Professor Michael Taggart
Dr Lee Borthwick
Professor Andrew Fisher
Dr Malcolm Brodlie
et al.
Acute cigarette smoke or extract exposure rapidly activates TRPA1-mediated calcium influx in primary human airway smooth muscle cells2021
Dr Iram Haq
Dr Mike Althaus
Dr Vinciane Saint-Criq
Dr Bernard Verdon
Dr Jen Townshend
et al.
Clinical and molecular characterisation of the R751L-CFTR mutation2021
Dr Michael Gray
CyFi-MAP: an interactive pathway-based resource for cystic fibrosis2021
Dr Vinciane Saint-Criq
Livia Delpiano
JinHeng Lin
Dr Michael Gray
Extracellular phosphate enhances the function of F508del-CFTR rescued by CFTR correctors2021
Dr Vinciane Saint-Criq
Livia Delpiano
John Casement
Jennifer Chika Onuora
Jia-Yu Lin
et al.
Choice of Differentiation Media Significantly Impacts Cell Lineage and Response to CFTR Modulators in Fully Differentiated Primary Cultures of Cystic Fibrosis Human Airway Epithelial Cells2020
Dr Michael White
Dr Rashmi Maheshwari
Dr Scott Anderson
Dr Rolando Berlinguer Palmini
Claire Jones
et al.
In situ analysis reveals that CFTR is expressed in only a small minority of β-cells in normal adult human pancreas2020
Dr Aaron Ions Gardner
Dr Iram Haq
Professor John Simpson
Dr Vinciane Saint-Criq
Dr Bernard Verdon
et al.
Recombinant Acid Ceramidase Reduces Inflammation and Infection in Cystic Fibrosis2020
Abi Marklew
Waseema Patel
Dr Michael Gray
Cigarette Smoke Exposure Induces Retrograde Trafficking of CFTR to the Endoplasmic Reticulum2019
Waseema Patel
Dr Michael Gray
Increases in cytosolic Ca2+ induce dynamin- and calcineurin-dependent internalisation of CFTR2019
Livia Delpiano
Dr Michael Gray
Location, location, location: lessons from airway epithelial anion channels2019
Dr Vinciane Saint-Criq
Dr Iram Haq
Dr Aaron Ions Gardner
Professor Christopher Ward
Dr Malcolm Brodlie
et al.
Real-Time, Semi-Automated Fluorescent Measurement of the Airway Surface Liquid pH of Primary Human Airway Epithelial Cells2019
Livia Delpiano
Dr Sarah Rice
Dr Michael Gray
Dr Vinciane Saint-Criq
Esomeprazole Increases Airway Surface Liquid pH in Primary Cystic Fibrosis Epithelial Cells2018
Salam Ibrahim
Mark Turner
Dr Vinciane Saint-Criq
Dr James Garnett
Dr Iram Haq
et al.
CK2 is a key regulator of SLC4A2- mediated Cl-/HCO3- exchange in human airway epithelia2017
Dr Vinciane Saint-Criq
Dr Michael Gray
Role of CFTR in epithelial physiology2017
Dr Iram Haq
Dr Michael Gray
Dr James Garnett
Professor Christopher Ward
Dr Malcolm Brodlie
et al.
Airway surface liquid homeostasis in cystic fibrosis: pathophysiology and therapeutic targets2016
Dr Michael Gray
Dr Zoltan Rakonczay
CFTR: A New Horizon in the Pathomechanism and Treatment of Pancreatitis2016
Mark Turner
Dr Vinciane Saint-Criq
Waseema Patel
Salam Ibrahim
Dr Burns Verdon
et al.
Hypercapnia Modulates cAMP Signalling and Cystic Fibrosis Transmembrane Conductance Regulator-dependent Anion and Fluid Secretion in Airway Epithelia2016
Abi Marklew
Dr Michael Gray
The Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Uses its C-Terminus to Regulate the A2B Adenosine Receptor2016
Dr James Garnett
Dr Michael Gray
Dr Malcolm Brodlie
Professor Christopher Ward
Airway epithelial cells secrete bicarbonate in response to acidic by-products of pseudomonas aeruginosa metabolism2015
Dr Zoltan Rakonczay
Viktoria Venglovecz
Dr Michael Gray
Alcohol Disrupts Levels and Function of the Cystic Fibrosis Transmembrane Conductance Regulator to Promote Development of Pancreatitis2015
Viktoria Venglovecz
Dr Zoltan Rakonczay
Dr Michael Gray
Potassium channels in pancreatic duct epithelial cells: their role, function and pathophysiological relevance2015
Dr Steven Broadbent
Professor Barry Argent
Dr Michael Gray
The cystic fibrosis transmembrane conductance regulator is an extracellular chloride sensor2015
Dr Michael Gray
CFTR Loss of Function After Alcohol Consumption and in Alcoholic Pancreatitis2014
Dr Zoltan Rakonczay
Dr Michael Gray
Viktoria Venglovecz
Ethanol and its non-oxidative metabolites profoundly inhibit CFTR function in pancreatic epithelial cells which is prevented by ATP supplementation2014
Abi Marklew
Dr Michael Gray
Exploring the Mechanisms Behind Cigarette Smoke-induced Internalization of CFTR2014
Dr Michael Gray
Professor John Robinson
Dr Jane Falconer
The role of cystic fibrosis transmembrane conductance regulator in antigen processing and presentation to CD4+T-cells2014
Viktoria Venglovecz
Dr Michael Gray
Dr Zoltan Rakonczay
The Role of Pancreatic Ductal Secretion in Protection Against Acute Pancreatitis in Mice2014
Dr James Garnett
Dr Michael Gray
Dr Malcolm Brodlie
Professor Christopher Ward
Erin Baker
et al.
Elevated Paracellular Glucose Flux across Cystic Fibrosis Airway Epithelial Monolayers Is an Important Factor for Pseudomonas aeruginosa Growth2013
Viktoria Venglovecz
Dr Zoltan Rakonczay
Dr Michael Gray
Ethanol and Its Non-Oxidative Metabolites Profoundly Inhibit CFTR Function in Pancreatic Epithelial Cells Which is Prevented by ATP Supplementation2013
Dr James Garnett
Hui Tunkamnerdthai
Dr Michael Gray
Protein phosphatase 1 coordinates CFTR-dependent airway epithelial HCO3- secretion by reciprocal regulation of apical and basolateral membrane Cl--HCO3- exchangers2013
Dr Michael Gray
Elevated Carbon Dioxide Blunts Mammalian cAMP Signaling Dependent on Inositol 1,4,5-Triphosphate Receptor-mediated Ca2+ Release2012
Dr John Winpenny
Dr Michael Gray
The anoctamin (TMEM16) gene family: calcium-activated chloride channels come of age2012
Dr Michael Gray
Effects of CFTR gene silencing by siRNA or the luminal application of a CFTR activator on fluid secretion from guinea-pig pancreatic duct cells2011
Dr Michael Gray
How to measure CFTR-dependent bicarbonate transport: from single channels to the intact epithelium2011
Dr Lee Borthwick
Phil Botha
Dr Malcolm Brodlie
Aaron Gardner
Dr David Bourn
et al.
Is CFTR-delF508 Really Absent from the Apical Membrane of the Airway Epithelium?2011
Dr James Garnett
Dr Michael Gray
Novel Role for Pendrin in Orchestrating Bicarbonate Secretion in Cystic Fibrosis Transmembrane Conductance Regulator (CFTR)-expressing Airway Serous Cells2011
Viktoria Venglovecz
Dr Zoltan Rakonczay
Dr Michael Gray
Pathophysiological relevance of apical large-conductance Ca2+ -activated potassium channels in pancreatic duct epithelial cells2011
Dr Zoltan Rakonczay
Dr Michael Gray
Professor Barry Argent
Viktoria Venglovecz
Substance P Inhibits Pancreatic Ductal Bicarbonate Secretion via Neurokinin Receptors 2 and 3 in the Guinea Pig Exocrine Pancreas2011
Viktoria Venglovecz
Dr Zoltan Rakonczay
Dr Michael Gray
Professor Barry Argent
Trypsin Reduces Pancreatic Ductal Bicarbonate Secretion by Inhibiting CFTR Cl- Channels and Luminal Anion Exchangers2011
Dr Michael Gray
CFTR is a mechanosensitive anion channel: a real stretch?2010
Viktoria Venglovecz
Dr Michael Gray
Dynamic Regulation of CFTR Bicarbonate Permeability by [Cl-]i and Its Role in Pancreatic Bicarbonate Secretion2010
Dr Malcolm Brodlie
Dr Michael McKean
Dr John Perry
Dr Burns Verdon
Dr Michael Gray
et al.
Primary bronchial epithelial cell culture from explanted cystic fibrosis lungs2010
Dr Zoltan Rakonczay
Viktoria Venglovecz
Professor Barry Argent
Dr Michael Gray
[Meeting Abstract] The Role of CFTR in the Stimulatory Effect of Chenodeoxycholate on Apical Anion Exchange Activity of Human Pancreatic Duct Cells2009
John Linley
Dr Stefan Boese
Professor Nicholas Simmons
Dr Michael Gray
A Voltage-Dependent Ca2+ Influx Pathway Regulates the Ca2+-Dependent Cl- Conductance of Renal IMCD-3 Cells2009
Viktoria Venglovecz
Dr Georgina Carr
Professor Barry Argent
Dr Michael Gray
Dr Zoltan Rakonczay
et al.
CFTR Expression But Not Cl- Transport Is Involved in the Stimulatory Effect of Bile Acids on Apical Cl-/HCO3- Exchange Activity in Human Pancreatic Duct Cells2009
Viktoria Venglovecz
Dr Zoltan Rakonczay
Professor Barry Argent
Dr Michael Gray
Chenodeoxycholate Activates Ion Channels in Guinea Pig Pancreatic Duct Cells2009
Dr Michael Gray
Inhibition of Protein Kinase CK2 Closes the CFTR Cl- Channel, but has no Effect on the Cystic Fibrosis Mutant Delta F508-CFTR CFTR2009
Dr Michael Gray
Stimulation of Mammalian G-protein-responsive Adenylyl Cyclases by Carbon Dioxide2009
Dr Zoltan Rakonczay
Professor Barry Argent
Dr Michael Gray
CFTR gene transfer to human cystic fibrosis pancreatic duct cells using a Sendai virus vector.2008
Dr Zoltan Rakonczay
Viktoria Venglovecz
Dr Michael Gray
Professor Barry Argent
Controversies in the role of SLC26 anion exchangers in pancreatic ductal bicarbonate secretion2008
Viktoria Venglovecz
Dr Zoltan Rakonczay
Dr Michael Gray
Professor Barry Argent
Effects of bile acids on pancreatic ductal bicarbonate secretion in guinea pig2008
John Linley
Professor Nicholas Simmons
Dr Michael Gray
Extracellular zinc stimulates a calcium-activated chloride conductance through mobilisation of intracellular calcium in renal inner medullary collecting duct cells2007
Dr Michael Gray
Orchestration of vectorial chloride transport by epithelia2007
Dr Burns Verdon
Professor Barry Argent
Dr Michael Gray
Sendai virus-mediated CFTR gene transfer to the airway epithelium2007
Professor Barry Argent
Dr Michael Gray
Cell physiology of pancreatic ducts2006
Dr Zoltan Rakonczay
Professor Barry Argent
Dr Michael Gray
CFTR gene transfer to human cystic fibrosis pancreatic duct cells upregulates apical CL-/HCO3(-) exchange activity2006
Dr Zoltan Rakonczay
Dr Amy Fearn
Dr Michael Gray
Professor Barry Argent
Characterization of H+ and HCO3- transporters in CFPAC-1 human pancreatic duct cells2006
Dr Michael Gray
Professor Barry Argent
Discussion2006
Dr Michael Gray
Discussion2006
Dr Michael Gray
Professor Barry Argent
Discussion2006
Dr Michael Gray
Discussion2006
Dr Michael Gray
Inefficient cationic lipid-mediated siRNA and antisense oligonucleotide transfer to airway epithelial cells in vivo2006
Dr Michael Gray
Orchestration of Vectorial Chloride Transport by Epithelia2006
Dr Michael Gray
Primary cilia and regulation of renal Na+ transport. Focus on "Heightened epithelial Na+ channel-mediated Na+ absorption in a murine polycystic kidney disease model epithelium lacking apical monocilia"2006
Dr Zoltan Rakonczay
Dr Michael Gray
Professor Barry Argent
SLC26 transporters and the inhibitory control of pancreatic ductal bicarbonate secretion2006
Dr Michael Gray
The physiology of anion transport: Tales of the bizarre and unexpected2006
Dr Zoltan Rakonczay
Dr Amy Fearn
Dr Michael Gray
Professor Barry Argent
Characterization of H+ and HCO3- transporters in CFPAC-1 human pancreatic duct cells2005
Dr Michael Gray
Professor Barry Argent
Effect of herpesvirus infection on pancreatic duct cell secretion2005
Dr Zoltan Rakonczay
Dr Michael Gray
Professor Barry Argent
Protein kinase C mediates the inhibitory effect of substance P on HCO 3- secretion from guinea pig pancreatic ducts2005
Dr Stefan Boese
Dr Michael Gray
Professor Nicholas Simmons
Volume-dependent and -independent activated anion conductances and their interaction in the renal inner medullary collecting duct (IMCD)2005
Dr Zoltan Rakonczay
Dr Amy Fearn
Dr Michael Gray
Professor Barry Argent
A novel basolateral bicarbonate transport mechanism in human pancreatic duct cells2004
Dr Michael Gray
Bicarbonate secretion: It takes two to tango2004
Professor Barry Argent
Dr Michael Gray
Identification of pancreatic K+ channels mediating ATP-stimulated Cl- secretion2004
Dr Stefan Boese
Omar Aziz
Professor Nicholas Simmons
Dr Michael Gray
Kinetics and regulation of a Ca2+-activated Cl- conductance in mouse renal inner medullary collecting duct cells2004
Dr Zoltan Rakonczay
Dr Michael Gray
Professor Barry Argent
Measurement of Intracellular pH in Pancreatic Duct Cells: A New Method for Calibrating the Fluorescence Data2004
Dr Michael Gray
Professor Barry Argent
Murine epithelial cells: Isolation and culture2004
Professor Barry Argent
Dr Michael Gray
Novel regulation of cystic fibrosis transmembrane conductance regulator (CFTR) channel gating by external chloride2004
Dr Michael Gray
Professor Barry Argent
Recombinant sendai virus mediates CFTR gene transfer to airway epithelium both in vitro and in vivo2004
Dr Michael Gray
The patch-clamp and planar lipid bilayer techniques: Powerful and versatile tools to investigate the CFTR Cl- channel2004
Dr Phillip Aldridge
Dr Michael Gray
Emeritus Professor Barry Hirst
Dr Anjam Khan
Who's talking to whom? Epithelial-bacterial pathogen interactions2004
Professor Barry Argent
Dr Michael Gray
Characterization of vectorial chloride transport pathways in the human pancreatic duct adenocarcinoma cell line HPAF2003
Dr Michael Gray
Omar Aziz
Professor Nicholas Simmons
Dr Stefan Boese
Intracellular Ca2+ directly regulates the Ca2+ activated Cl conductance in mouse inner medullary collecting duct cells2003
Dr Stefan Boese
Omar Aziz
Professor Nicholas Simmons
Dr Michael Gray
Intracellular Ca2+ directly regulates the Ca2+-activated Cl- conductance in mouse inner medullary collecting duct cells2003
Professor Barry Argent
Dr Michael Gray
Molecular & functional analysis of Cl- and K+ channels in HPAF cells2003
Dr Michael Gray
Recombinant Sendai virus mediates CFTR gene transfer to airway epithelium both ex vivo and in vivo2003
Dr Michael Gray
Professor Barry Argent
Recombinant Sendai virus-mediated CFTR cDNA transfer2003
Professor Barry Argent
Dr Michael Gray
Regulation of CFTR by extracellular anions is modulated by cytosolic calcium and phosphatase activity2003
Dr Michael Gray
Professor Barry Argent
Substance P inhibits bicarbonate secretion from guinea pig pancreatic ducts by modulating an anion exchanger2003
Dr Michael Gray
Professor Barry Argent
Substance P inhibits bicarbonate secretion in guinea pig panceatic ducts by modulating an anion exchanger2003
Dr Michael Gray
Designer pharmacotherapy for the treatment of cystic fibrosis2002
Dr Michael Gray
Designer pharmacotherapy for the treatment of cystic fibrosis: Commentary on Zegarra-Moran et al2002
Dr Michael Gray
Dr John Winpenny
Professor Barry Argent
Properties and role of calcium-activated chloride channels in pancreatic duct cells2002
Dr Michael Gray
Dr John Winpenny
Dr Catherine O'Reilly
Professor Barry Argent
Properties and role of calcium-activated chloride channels in pancreatic duct cells2002
Dr Michael Gray
Professor Barry Argent
Regulation of murine airway surface liquid volume by CFTR and Ca2+-activated Cl- conductances2002
Dr Stefan Boese
Professor John Sayer
Dr Gavin Stewart
Dr Michael Glanville
Dr Michael Gray
et al.
Renal expression of Ca2+-activated Cl- channels2002
Dr Stefan Boese
Professor John Sayer
Dr Gavin Stewart
Dr Michael Glanville
Dr Michael Gray
et al.
Renal expression of Ca2+-activated Cl- channels2002
Dr Michael Gray
Omar Aziz
Role of capacitative calcium entry in secretion by A549 epithelial cells [abstract]2002
Dr Michael Gray
Professor Barry Argent
150 mM HCO3- - How does the pancreas do it? Clues from computer modelling of the duct cell2001
Dr Michael Gray
Correction of delF508-CFTR activity with benzo(c)quinolizinium compounds through facilitation of its processing in cystic fibrosis airway cells2001
Dr Michael Gray
Dr Catherine O'Reilly
Dr John Winpenny
Professor Barry Argent
Functional interactions of HCO3- with cystic fibrosis transmembrane conductance regulator2001
Dr Michael Gray
Omar Aziz
Multiple calcium entry pathways in A549 alveolar type II epithelial cells2001
Dr Gavin Stewart
Omar Aziz
Professor Nicholas Simmons
Dr Michael Gray
Regulation of an outwardly rectifying chloride conductance in renal epithelial cells by external and internal calcium2001
Professor John Sayer
Dr Gavin Stewart
Dr Stefan Boese
Dr Michael Gray
Professor Simon Pearce
et al.
The voltage-dependent of Cl- channel ClC-5 and plasma membrane Cl- conductances of mouse renal collecting duct cells (mIMCD-3)2001
Dr Michael Gray
Dr Catherine O'Reilly
Dr John Winpenny
Professor Barry Argent
Anion interactions with CFTR and consequences for HCO3- transport in secretory epithelia2000
Dr Michael Gray
Dr Colin Brown
Professor Nicholas Simmons
Bradykinin regulation of salt transport across mouse inner medullary collecting duct epithelium involves activation of a Ca2+ -dependent Cl- conductance2000
Dr Stefan Boese
Dr Michael Glanville
Omar Aziz
Dr Michael Gray
Professor Nicholas Simmons
et al.
Ca2+ and cAMP-activated Cl- conductances mediate Cl- secretion in a mouse renal inner medullary collecting duct cell line2000
Dr Catherine O'Reilly
Dr John Winpenny
Professor Barry Argent
Dr Michael Gray
Cystic fibrosis transmembrane conductance regulator currents in guinea pig pancreatic duct cells: Inhibition by bicarbonate ions2000
Dr Catherine O'Reilly
Dr John Winpenny
Professor Barry Argent
Dr Michael Gray
Cystic fibrosis transmembrane conductance regulator currents in guinea pig pancreatic duct cells: inhibition by bicarbonate ions2000
Professor Barry Argent
Dr Michael Gray
Regulation of a hyperpolarization-activated chloride current in murine respiratory ciliated cells2000
Dr Stefan Boese
Dr Michael Glanville
Dr Michael Gray
Professor Nicholas Simmons
The swelling-activated anion conductance in the mouse renal inner medullary collecting duct cell line mIMCD-K22000
Jeanette Adair
Darren Stephenson
Dr Michael Gray
Professor Barry Argent
Anion secretion and intracellular calcium concentration in a human pancreatic duct cell line (HPAF)1999
Dr Stefan Boese
Professor Nicholas Simmons
Dr Michael Gray
ATP and forskolin stimulate transepithelial Cl- secretion in mouse renal inner medullary collecting duct cells (mIMCD-K2) by activation of distinct Cl- conductances1999
Dr Gavin Stewart
Dr Michael Glanville
Dr Michael Gray
Professor Nicholas Simmons
ATP stimulates a chloride conductance in the mIMCD-3 cell line1999
Jeanette Adair
Professor Barry Argent
Dr Michael Gray
ATP-induced [CA2+]i oscillations in a human pancreatic duct cell line (HPAF)1999
Dr Michael Gray
Professor Barry Argent
Development of substituted benzo[c]quinolizinium compounds as novel activators of the cystic fibrosis chloride channel1999
Dr Michael Gray
Professor Barry Argent
Novel activators of CFTR in native epithelial cells1999
Professor Barry Argent
Dr Michael Gray
Substituted benzoquinolizinium compounds activate CFTR in native pancreatic duct cells1999
Dr Stefan Boese
Dr Michael Glanville
Professor Nicholas Simmons
Dr Michael Gray
The swelling-activated chloride conductance in mIMCD-K2 cells is associated with multiple CLC expression.1999