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Browsing publications by Professor Alison Tyson-Capper.

Newcastle AuthorsTitleYearFull text
Dr Sami Anjum
Josh Kirby
Professor Alison Tyson-Capper
Ceramic Biomaterials: what are their biological implications?2021
Vic Hart
Dr Hannah Gautrey
Josh Kirby
Professor Alison Tyson-Capper
HER2 splice variants in breast cancer: their impact on diagnosis and treatment outcomes2021
Vic Hart
Marco Silipo
Swapna Satam
Dr Hannah Gautrey
Professor John Kirby
et al.
HER2-PI9 and HER2-I12: two novel and functionally active splice variants of the oncogene HER2 in breast cancer2021
Shannon Jamieson
Amy Mawdesley
Professor David Deehan
Professor John Kirby
Professor Alison Tyson-Capper
et al.
Inflammatory responses to metal oxide ceramic nanopowders2021
Shannon Jamieson
Professor Alison Tyson-Capper
Dr Philip Hyde
Professor John Kirby
Understanding the immunobiology of orthopaedic biomaterials2021
Amy Mawdesley
Dr Sami Anjum
Professor John Kirby
Professor Alison Tyson-Capper
Effect of cobalt ions on chemokine expression: Case report of immune cell infiltration in patient undergoing replacement of a metal-on-metal implant2020
Anna Stanton
Dr Catherine Mowbray
Marcelo Lanz
Dr Karen Brown
Paul Hilton
et al.
Topical Estrogen Treatment Augments the Vaginal Response to Escherichia coli Flagellin2020
Dr Richard Hetherington
Professor Alison Tyson-Capper
Research led teaching to Teaching led Research2019
Professor Alison Tyson-Capper
Dr Hannah Gautrey
Regulation of Mcl-1 alternative splicing by hnRNP F, H1 and K in breast cancer cells2018
Dr Marina Danilenko
Caroline Dalgliesh
Dr Ingrid Ehrmann
Professor Alison Tyson-Capper
Dr Gavin Clowry
et al.
Binding site density enables paralog-specific activity of SLM2 and Sam68 proteins in Neurexin2 AS4 splicing control2017
Marco Silipo
Dr Hannah Gautrey
Swapna Satam
Professor Tom Lennard
Professor Alison Tyson-Capper
et al.
How is Herstatin, a tumor suppressor splice variant of the oncogene HER2, regulated?2017
Ased Ali
Dr Catherine Mowbray
Marcelo Lanz
Anna Stanton
Paul Hilton
et al.
Targeting Deficiencies in the TLR5 Mediated Vaginal Response to Treat Female Recurrent Urinary Tract Infection2017
Dr Helen Lawrence
Professor David Deehan
James Holland
Dr Sami Anjum
Amy Mawdesley
et al.
Cobalt ions recruit inflammatory cells in vitro through human Toll-like receptor 42016
Dr Sami Anjum
Dr Helen Lawrence
James Holland
Professor John Kirby
Professor David Deehan
et al.
Effect of cobalt-mediated Toll-like receptor 4 activation on inflammatory responses in endothelial cells2016
Dr Helen Lawrence
Amy Mawdesley
James Holland
Professor John Kirby
Professor David Deehan
et al.
Targeting Toll-like receptor 4 prevents cobalt-mediated inflammation2016
Dr Andrew Best
Dr Katherine James
Gerald Hysenaj
Professor Alison Tyson-Capper
Professor David Elliott
et al.
Transformer2 proteins protect breast cancer cells from accumulating replication stress by ensuring productive splicing of checkpoint kinase 12016
Marco Silipo
Dr Hannah Gautrey
Professor Alison Tyson-Capper
Deregulation of splicing factors and breast cancer development2015
Dr Gareth Waring
Dr Judith Bulmer
Professor Steve Robson
Professor Alison Tyson-Capper
Inflammatory Signalling in Fetal Membranes: Increased Expression Levels of TLR 1 in the Presence of Preterm Histological Chorioamnionitis2015
Dr Hannah Gautrey
Anna-Lena Dittrich
Professor Thomas Lennard
Professor Alison Tyson-Capper
SRSF3 and hnRNP H1 regulate a splicing hotspot of HER2 in breast cancer cells2015
Elaine Hong
Dr Andrew Best
Dr Hannah Gautrey
Professor David Elliott
Professor Alison Tyson-Capper
et al.
Unravelling the RNA-Binding Properties of SAFB Proteins in Breast Cancer Cells2015
Dr Helen Lawrence
Professor David Deehan
James Holland
Professor John Kirby
Professor Alison Tyson-Capper
et al.
Can cobalt from metal-on-metal joints activate human TLR4 and cause an inflammatory response?2014
Andy Best
Caroline Dalgliesh
Elaine Hong
Mahsa Kheirollahi Kouhestani
Dr Yaobo Xu
et al.
Human Tra2 proteins jointly control a CHEK1 splicing switch among alternative and constitutive target exons2014
Professor Janet Eyre
Ian Harvey
Professor Thomas Lennard
Professor Alison Tyson-Capper
Dr Annette Meeson
et al.
Reversing paclitaxel resistance in ovarian cancer cells via inhibition of the ABCB1 expressing side population2014
Anna-Lena Dittrich
Dr Hannah Gautrey
Professor Alison Tyson-Capper
The HER2 Signaling Network in Breast Cancer-Like a Spider in its Web2014
Dr Helen Lawrence
Professor David Deehan
Professor John Kirby
Professor Alison Tyson-Capper
The immunobiology of cobalt: demonstration of a potential aetiology for inflammatory pseudotumours after metal-on-metal replacement of the hip2014
Dr Andrew Best
Caroline Dalgliesh
Mahsa Kheirollahi Kouhestani
Dr Marina Danilenko
Dr Ingrid Ehrmann
et al.
Tra2 protein biology and mechanisms of splicing control2014
Dr Hannah Gautrey
Professor Alison Tyson-Capper
Clinical significance of HER-2 splice variants in breast cancer progression and drug resistance2013
Emeritus Professor Nick Europe-Finner
Professor Alison Tyson-Capper
Estrogen Alters the Splicing of Type 1 Corticotropin-Releasing Hormone Receptor in Breast Cancer Cells2013
Andy Best
Dr Ingrid Ehrmann
Mahsa Kheirollahi Kouhestani
Professor Alison Tyson-Capper
Professor David Elliott
et al.
Expression of Tra2ß in cancer cells as a potential contributory factor to neoplasia and metastasis2013
Dr Gareth Waring
Professor Steve Robson
Dr Judith Bulmer
Professor Alison Tyson-Capper
Inflammatory signalling in fetal membranes: the transcriptome of chorioamnionitis2013
Dr Gareth Waring
Professor Steve Robson
Dr Judith Bulmer
Professor Alison Tyson-Capper
Inflammatory Signalling in Fetal Membranes: The Transcriptome of Chorioamnionitis2013
Dr Gareth Waring
Professor Steve Robson
Dr Judith Bulmer
Professor Alison Tyson-Capper
Inflammatory signalling in fetal membranes: the transcriptome of chorioamnionitis2013
Professor Alison Tyson-Capper
Dr Helen Lawrence
James Holland
Professor David Deehan
Professor John Kirby
et al.
Metal-on-metal hips: cobalt can induce an endotoxin-like response2013
David Cork
Professor Steve Robson
Dr Julian Venables
Professor Alison Tyson-Capper
Myometrial-Specific Spatiotemporal Splicing Patterns in Pregnancy2013
Dr David Cork
Professor Steve Robson
Dr Julian Venables
Professor Alison Tyson-Capper
Myometrial-specific spatiotemporal splicing patterns in pregnancy2013
Professor Alison Tyson-Capper
Dr Helen Lawrence
James Holland
Professor David Deehan
Professor John Kirby
et al.
The Molecular Mechanism of Cell Activation by Cobalt Ions. Comment on Ninomiya et al.: Metal Ions Activate Vascular Endothelial Cells and Increase Lymphocyte Chemotaxis and Binding2013
Dr Elaine Hong
Professor David Elliott
Professor Alison Tyson-Capper
Identification of SAFB1 and SAFB2 Target Genes within the Oestrogen Receptor-Signalling Pathway in Breast Cancer Cells2012
Dr Amena Shelleh
Professor John Kirby
Professor Steve Robson
Professor Alison Tyson-Capper
Preterm Birth: A Modulatory Role for HMGB1?2012
Dr David Cork
Emeritus Professor Tom Lennard
Professor Alison Tyson-Capper
Progesterone receptor (PR) variants exist in breast cancer cells characterised as PR negative2012
Dr David Cork
Professor Thomas Lennard
Professor Alison Tyson-Capper
Progesterone receptor (PR) variants exist in breast cancer cells characterised as PR negative2012
Dr Hannah Gautrey
Professor Alison Tyson-Capper
Regulation of Mcl-1 by SRSF1 and SRSF5 in cancer cells2012
Elaine Hong
Dr Hannah Gautrey
Professor David Elliott
Professor Alison Tyson-Capper
SAFB1 and SAFB2 mediated transcriptional repression: relevance in cancer2012
Dr David Cork
Professor Thomas Lennard
Professor Alison Tyson-Capper
The Functional Impact of Progesterone Receptor Alternative Splicing in Breast Cancer Cells2012
Professor Alison Tyson-Capper
Dr Kelly Britton
Professor Steve Robson
Dr Annette Meeson
The temporal and spatial expression patterns of ABCG2 in the developing human heart2012
Dr Farah Sethna
Professor Alison Tyson-Capper
Liz Shiells
Professor Steve Robson
The expression of glucocorticoid receptor in human myometrium in pregnancy and labour2011
Professor Alison Tyson-Capper
Qi Zhang
Professor Steve Robson
Anti-Inflammatory Action of Progesterone on TLR-4 and COX-2 Activation Is Not Mediated by Nuclear Progesterone Receptors2010
Professor John Kirby
Liz Shiells
Professor Steve Robson
Professor Alison Tyson-Capper
Characterisation of HMGB1 in the Human Myometrium during Pregnancy2010
Professor Alison Tyson-Capper
Effect of Oestrogen on RNA-Binding Splicing Regulators in Breast Cancer Cells2010
David Cork
Professor Thomas Lennard
Professor Alison Tyson-Capper
Hormone Responsive Expression of Naturally Occurring Truncated Progesterone Receptor Variants in Breast Cancer Cell Lines2009
Professor Alison Tyson-Capper
Liz Shiells
Professor Steve Robson
Interplay between polypyrimidine tract binding protein-associated splicing factor and human myometrial progesterone receptors2009
Professor Alison Tyson-Capper
Liz Shiells
Professor Steve Robson
Myometrial Progesterone Receptors at Term and in Labour: The Story Continues2009
Kelly Harper
Professor Steve Robson
Emeritus Professor Nick Europe-Finner
Professor Alison Tyson-Capper
Acetylation and phosphorylation status of HDACS and the epigenetics of myometrial quiescent and pro-contractile genes2008
Dr Marie Smith
Professor Alison Tyson-Capper
Professor Steve Robson
Alternative signalling pathways contribute towards mediation of anti-inflammatory properties of progestins2008
Dr David Cork
Professor Thomas Lennard
Professor Alison Tyson-Capper
Alternative splicing and the progresterone receptor in breast cancer2008
Kelly Harper
Professor Alison Tyson-Capper
Complexity of COX-2 gene regulation2008
Dr Farah Sethna
Professor Alison Tyson-Capper
Liz Shiells
Professor Steve Robson
Expression of glueocorticoid receptor in human myometrium during pregnancy and labour2008
Liz Shiells
Professor Steve Robson
Professor Alison Tyson-Capper
Progesterone and progesterone receptor c in human myometrial and amnion derived WISH cells2008
Professor Alison Tyson-Capper
Professor Steve Robson
Progestins and the glucocorticoid receptor in human myometrial and amnion-derived WISH cells2008
Professor Alison Tyson-Capper
Liz Shiells
Professor Steve Robson
The ambiguity of myometrial progesterone receptor expression in pregnancy and labour2008
Professor Alison Tyson-Capper
Alternative splicing: An important mechanism for myometrial gene regulation that can be manipulated to target specific genes associated with preterm labour2007
Professor Alison Tyson-Capper
Dr David Cork
Liz Shiells
Andrew Loughney
Characterization of cellular retinoid-binding proteins in human myometrium during pregnancy2006
Professor Alison Tyson-Capper
Emeritus Professor Nick Europe-Finner
Novel targeting of COX-2 pre-mRNA using antisense morpholino oligonucleotides: suppression of Cox-2 activity in human myometrial cells and amnion-derived WISH cells2006
Professor Alison Tyson-Capper
Emeritus Professor Nick Europe-Finner
Novel targeting of COX-2 pre-mRNA using antisense morpholino oligonucleotides: Suppression of COX-2 activity in human myometrial cells and amnion-derived wish cells.2006
Professor Alison Tyson-Capper
Emeritus Professor Nick Europe-Finner
Novel targeting of cyclooxygenase-2 (COX-2) pre-mRNA using antisense morpholino oligonucleotides directed to the 3′ acceptor and 5′ donor splice sites of exon 4: Suppression of COX-2 activity in human amnion-derived WISH and myometrial cells2006
Professor Alison Tyson-Capper
Dr David Cork
Elizabeth Kokkinos
Emeritus Professor Nick Europe-Finner
Andrew Loughney
et al.
The role of the retinoids in the differentiation of the myometrium during pregnancy2006
Dr Magdalena Karolczak-Bayatti
Professor Alison Tyson-Capper
Professor Steve Robson
Emeritus Professor Nick Europe-Finner
Transcriptional regulation of the protein kinase a regulatory subunit II alpha (RIIalpha PKA) in the myometrium.2006
Dr Jarrod Bailey
Professor Alison Tyson-Capper
Kate Gilmore
Professor Steve Robson
Emeritus Professor Nick Europe-Finner
et al.
Identification of human myometrial target genes of the cAMP pathway: The role of cAMP-response element binding (CREB) and modulator (CREMα and CREMτ2α) proteins2005
Dr Robert Phillips
Professor Alison Tyson-Capper
Dr Jarrod Bailey
Professor Steve Robson
Emeritus Professor Nick Europe-Finner
et al.
Regulation of expression of the chorionic gonadotropin/luteinizing hormone receptor gene in the human myometrium: Involvement of specificity protein-1 (Sp1), Sp3,Sp4, Sp-like proteins, and histone deacetylases2005
Professor Alison Tyson-Capper
Dr Jarrod Bailey
Professor Steve Robson
Emeritus Professor Nick Europe-Finner
The switch in alternative splicing of cyclic AMP-response element modulator protein CREMτ2α (activator) to CREMα (repressor) in human myometrial cells is mediated by SRp402005
Professor Alison Tyson-Capper
Professor Steve Robson
Emeritus Professor Nick Europe-Finner
Alternative splicing of the adenylyl cyclase stimulatory G-protein Gαs is regulated by SF2/ASF and heterogeneous nuclear ribonucleoprotein A1 (hnRNPA1) and involves the use of an unusual TG 3′-splice site2002
Dr Jarrod Bailey
Dr Robert Phillips
Professor Alison Tyson-Capper
Kate Gilmore
Professor Steve Robson
et al.
Characterization and functional analysis of cAMP response element modulator protein and activating transcription factor 2 (ATF2) isoforms in the human myometrium during pregnancy and labor: Identification of a novel ATF2 species with potent transactivation properties2002
Professor Alison Tyson-Capper
Professor Steve Robson
Emeritus Professor Nick Europe-Finner
Spatio-temporal expression of the Trans-acting splicing factors SF2/ASF and heterogeneous ribonuclear proteins A1/A1B in the myometrium of the pregnant human uterus: A molecular mechanism for regulating regional protein isoform expression in Vivo2000