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Browsing publications by Professor Anthony Moorman.

Newcastle AuthorsTitleYearFull text
Professor Anthony Moorman
ETV6::RUNX1 Acute Lymphoblastic Leukemia: how much therapy is needed for cure?2024
Dr Amir Enshaei
Melvin Joy
Ellie Butler
Professor Anthony Moorman
A robust and validated integrated prognostic index for defining risk groups in adult acute lymphoblastic leukemia: an EWALL collaborative study2024
Dr Hayden Bell
Dr Helen Blair
Samantha Jepson Gosling
Dr Martin Galler
Dan Astley
et al.
Combination p53 activation and BCL-xL/BCL-2 inhibition as a therapeutic strategy in high-risk and relapsed acute lymphoblastic leukemia2024
Professor Anthony Moorman
Noncoding mutations drive persistence of a founder preleukemic clone which initiates late relapse in T-ALL2024
Emilio Barretta
Dr Tom Creasey
Professor Anthony Moorman
Results from UKALL60+, a phase 2 study in older patients with untreated acute lymphoblastic leukemia2024
Professor Anthony Moorman
Targeted treatment options for paediatric B-cell precursor acute lymphoblastic leukaemia patients with constitutional or somatic chromosome 21 alterations2024
Ellie Butler
Professor Christine Harrison FRCPath FMedSci
Professor Anthony Moorman
Clinical characteristics and outcomes of B-cell precursor ALL with MEF2D rearrangements: a retrospective study by the Ponte di Legno Childhood ALL Working Group2023
Melvin Joy
Dr Amir Enshaei
Professor Anthony Moorman
Cranial radiotherapy has minimal benefit in children with central nervous system involvement in T-ALL2023
Dr Richard Gallon
Rachel Phelps
Christine Hayes
Dr Dino Masic
Professor Julie Irving
et al.
Detection of constitutional mismatch repair deficiency in children and adolescents with acute lymphoblastic leukemia2023
Dr Paul Sinclair
Dr Ruth Cranston
Prahlad Raninga
Joanna Cheng
Rebecca Hanna
et al.
Disruption to the FOXO-PRDM1 axis resulting from deletions of chromosome 6 in acute lymphoblastic leukaemia2023
Professor Anthony Moorman
EBV-driven lymphoid neoplasms associated with pediatric ALL maintenance therapy2023
Claire Schwab
Dr Ruth Cranston
Dr Sarra Ryan
Ellie Butler
Emily Winterman
et al.
Integrative genomic analysis of childhood acute lymphoblastic leukaemia lacking a genetic biomarker in the UKALL2003 clinical trial2023
Dr Simon Bomken
Dr Amir Enshaei
Dr Ed Schwalbe
Dr Aneta Mikulasova
Dr Masood Zaka
et al.
Molecular characterisation and clinical outcome of B-cell precursor acute lymphoblastic leukaemia with IG-MYC rearrangement2023
Professor Anthony Moorman
Outcome for Children and Young Adults With T-Cell ALL and Induction Failure in Contemporary Trials2023
Dr Amir Enshaei
Jude Gibson
Dr Sulaiman Lawal
Professor Anthony Moorman
Real-world evaluation of UK high hyperdiploidy profile using a large cohort of patients provided by HARMONY data platform2023
Dr Hayden Bell
Dr Helen Blair
Mankaran Singh
Professor Anthony Moorman
Professor Olaf Heidenreich
et al.
Targeting WEE1 kinase as a p53-independent therapeutic strategy in high-risk and relapsed acute lymphoblastic leukemia2023
Sarra Ryan
Dr Ruth Cranston
Claire Schwab
Dr Matthew Bashton
Dr Paul Sinclair
et al.
The genomic landscape of acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 212023
Dr Amir Enshaei
Professor Anthony Moorman
The Prognostic Effect of IKZF1 Deletions in ETV6::RUNX1 and High Hyperdiploid Childhood Acute Lymphoblastic Leukemia2023
Sarra Ryan
Claire Schwab
Dr Richard Yim
Dr Ruth Cranston
Dr Lisa Russell
et al.
Whole genome sequencing provides comprehensive genetic testing in childhood B-cell acute lymphoblastic leukaemia2023
Professor Anthony Moorman
Activity and toxicity of intramuscular 1000 iu/m2 polyethylene glycol-E. coli L-asparaginase in the UKALL 2003 and UKALL 2011 clinical trials2022
Dr Tobias Menne
Professor Anthony Moorman
Addition of four doses of rituximab to standard induction chemotherapy in adult patients with precursor B-cell acute lymphoblastic leukaemia (UKALL14): a phase 3, multicentre, randomised controlled trial2022
Professor Anthony Moorman
Clonal dynamics in pediatric B-cell precursor acute lymphoblastic leukemia with very early relapse2022
Dr Tom Creasey
Emilio Barretta
Dr Sarra Ryan
Ellie Butler
Dr Daniel Leongamornlert
et al.
Genetic and genomic analysis of acute lymphoblastic leukaemia in older adults reveals a distinct profile of abnormalities: analysis of 210 patients from the UKALL14 and UKALL60+ clinical trials2022
Claire Schwab
Daniel Murdy
Ellie Butler
Dr Amir Enshaei
Emily Winterman
et al.
Genetic characterisation of childhood B-other-acute lymphoblastic leukaemia in UK patients by fluorescence in situ hybridisation and Multiplex Ligation-dependent Probe Amplification2022
Angeli Ambayya
Professor Anthony Moorman
Dr Jeyanthy Eswaran
Sarina Sulong
Genetic profiles and risk stratification in adult de novo acute myeloid leukaemia in relation to age, gender, and ethnicity: A study from Malaysia2022
Dr Deepali Pal
Dr Helen Blair
Sean Hockney
Dr Melanie Beckett
Mankaran Singh
et al.
hiPSC-derived bone marrow milieu identifies a clinically actionable driver of niche-mediated treatment resistance in leukemia2022
Dr Tobias Menne
Professor Anthony Moorman
In-vivo T-cell depleted reduced-intensity conditioned allogeneic haematopoietic stem-cell transplantation for patients with acute lymphoblastic leukaemia in first remission: results from the prospective, single-arm evaluation of the UKALL14 trial2022
Professor Anthony Moorman
Emilio Barretta
Ellie Butler
Eleanor Ward
Dr Amir Enshaei
et al.
Prognostic impact of chromosomal abnormalities and copy number alterations in adult B-cell precursor acute lymphoblastic leukaemia: a UKALL14 study2022
Professor Anthony Moorman
Dr Lina Hamadeh
Prognostic value of Oncogenetic mutations in pediatric T Acute Lymphoblastic Leukemia: a comparison of UKALL2003 and FRALLE2000T protocols2022
Professor Anthony Moorman
Dr Grace Antony
Ellie Butler
Dr Amir Enshaei
Professor Christine Harrison FRCPath FMedSci
et al.
Time to Cure for Childhood and Young Adult Acute Lymphoblastic Leukemia Is Independent of Early Risk Factors: Long-Term Follow-Up of the UKALL2003 Trial2022
Claire Schwab
Professor Anthony Moorman
SSBP2-CSF1R is a recurrent fusion in B-lineage acute lymphoblastic leukemia with diverse genetic presentation and variable outcome2021
Ellie Butler
Professor Christine Harrison FRCPath FMedSci
Professor Anthony Moorman
Clinical characteristics and outcomes of B-ALL with ZNF384 rearrangements: a retrospective analysis by the Ponte di Legno Childhood ALL Working Group2021
Dr Amir Enshaei
Professor Anthony Moorman
Defining low-risk high hyperdiploidy in patients with paediatric acute lymphoblastic leukaemia: a retrospective analysis of data from the UKALL97/99 and UKALL2003 clinical trials2021
Daniel Murdy
Professor Anthony Moorman
DNA-TG and risk of sinusoidal obstruction syndrome in childhood acute lymphoblastic leukemia2021
Emilio Barretta
Dr Tobias Menne
Professor Anthony Moorman
IKZF1 alterations are not associated with outcome in 498 adults with B-precursor ALL enrolled in the UKALL14 trial2021
Dr Amir Enshaei
Professor Anthony Moorman
Minimal Residual Disease, Long-Term Outcome, and IKZF1 Deletions in Down Syndrome Acute Lymphoblastic Leukemia in a Matched Cohort Study2021
Professor Anthony Moorman
Professor Julie Irving
Risk factors and outcomes in children with high-risk B-cell precursor and T-cell relapsed acute lymphoblastic leukaemia: combined analysis of ALLR3 and ALL-REZ BFM 2002 clinical trials2021
Dr Tom Creasey
Dr Amir Enshaei
Claire Schwab
Kathryn Watts
Gavin Cuthbert
et al.
Single nucleotide polymorphism (SNP) array-based signature of low hypodiploidy in acute lymphoblastic leukemia2021
Dr Amir Enshaei
Professor Christine Harrison FRCPath FMedSci
Claire Schwab
Professor Anthony Moorman
A validated novel continuous prognostic index to deliver stratified medicine in pediatric acute lymphoblastic leukemia2020
Professor Anthony Moorman
Claire Schwab
Emily Winterman
Dr Frederik van Delft
Professor Christine Harrison FRCPath FMedSci
et al.
Adjuvant tyrosine kinase inhibitor therapy improves outcome for children and adolescents with acute lymphoblastic leukaemia who have an ABL-class fusion2020
Dr Ed Schwalbe
Dr Peter Carey
Professor Stephen O'Brien
Professor Anthony Moorman
Emilio Barretta
et al.
Challenges of starting treatment protocols for acute lymphoblastic leukaemia in a low-income setting — the Blantyre experience2020
Dr Matthew Bashton
Robin Hollis
Dr Sarra Ryan
Claire Schwab
Professor Christine Harrison FRCPath FMedSci
et al.
Concordance of copy number abnormality detection using SNP arrays and Multiplex Ligation-dependent Probe Amplification (MLPA) in acute lymphoblastic leukaemia2020
Professor Anthony Moorman
Germline variants in predisposition genes in children with down syndrome and acute lymphoblastic leukemia2020
Professor Anthony Moorman
IKZF1 deletions in pediatric acute lymphoblastic leukemia: still a poor prognostic marker?2020
Dr Jennifer Warrender
Professor Anthony Moorman
Dr Phillip Lord
A fully computational and reasonable representation for karyotypes2019
Professor James Allan
Professor Christine Harrison FRCPath FMedSci
Professor Anthony Moorman
Author correction: Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia2019
Professor Anthony Moorman
Dr Amir Enshaei
Dr Tobias Menne
Clinical Efficacy of a Novel Validated Prognostic Index for Trial Design in Adult Acute Lymphoblastic Leukaemia2019
Dr Amir Enshaei
Professor Anthony Moorman
Combining Genotype Profiling with MRD for More Accurate Prognostication in Acute Lymphoblastic Leukemia2019
Professor James Allan
Professor Anthony Moorman
Identification of four novel associations for B-cell acute lymphoblastic leukaemia risk2019
Professor Anthony Moorman
Dr Amir Enshaei
Minimal Residual Disease and IKZF1 As Predictors of Relapse, and Increased Treatment Related Mortality in Down Syndrome Acute Lymphoblastic Leukemia: A Unique and Large International Matched Case-Control Study2019
Dr Lina Hamadeh
Professor Julie Irving
Professor Anthony Moorman
Outcomes of patients with childhood B-cell precursor acute lymphoblastic leukaemia with late bone marrow relapses: long-term follow-up of the ALLR3 open-label randomised trial2019
Dr Paul Sinclair
Dr Sarra Ryan
Dr Matthew Bashton
Shaun Hollern
Rebecca Hanna
et al.
SH2B3 inactivation through CN-LOH-12q is uniquely associated with B-cell precursor ALL with iAMP21 or other chromosome 21 gain2019
Dr Tom Creasey
Dr Amir Enshaei
Kathryn Watts
Gavin Cuthbert
Claire Schwab
et al.
Single Nucleotide Polymorphism Array-Based Signature of Genetic Ploidy Groups in Acute Lymphoblastic Leukemia2019
Dr Lina Hamadeh
Dr Amir Enshaei
Claire Schwab
Professor Christine Harrison FRCPath FMedSci
Professor Anthony Moorman
et al.
Validation of the United Kingdom copy-number alteration classifier in 3239 children with B-cell precursor ALL2019
Dr Peixun Zhou
Dr Amir Enshaei
Alex Newman
Dr Amy Erhorn
Amy Barnard
et al.
A genomic classification model enables risk stratification of paediatric endemic Burkitt lymphoma2018
Dr Peixun Zhou
Dr Amir Enshaei
Alex Newman
Dr Amy Erhorn
Amy Barnard
et al.
A Genomic Classification Model Enables Risk Stratification of Paediatric Endemic Burkitt Lymphona in Malawi2018
Dr Paul Sinclair
Dr Helen Blair
Dr Sarra Ryan
Dr Lars Buechler
Joanna Cheng
et al.
Dynamic clonal progression in xenografts of acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 212018
Professor James Allan
Professor Christine Harrison FRCPath FMedSci
Professor Anthony Moorman
Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia2018
Professor Julie Irving
Professor Anthony Moorman
International cooperative study identifies treatment strategy in childhood ambiguous lineage leukemia2018
Dr Lucy Chilton
Professor Anthony Moorman
Richard Feltbower
Long-term survival after childhood acute lymphoblastic leukaemia: Population-based trends in cure and relapse by clinical characteristics2018
Dr Kate Potter
Professor Anthony Moorman
Professor Caroline Relton
Professor John Mathers
Dr Gordon Strathdee
et al.
Maternal red blood cell folate and infant vitamin B12 status influence methylation of genes associated with childhood acute lymphoblastic leukaemia2018
Dr Sarah Jenkinson
Dr Sujith Samarasinghe
Professor Anthony Moorman
Prognostic impact of the absence of biallelic deletion at the TRG locus for pediatric patients with T-cell acute lymphoblastic leukemia treated on the Medical Research Council UK Acute Lymphoblastic Leukemia 2003 trial2018
Professor Anthony Moorman
Relapse in teenage and young adult patients treated on a paediatric minimal residual disease stratified ALL treatment protocol is associated with a poor outcome: Results from UKALL20032018
Professor Anthony Moorman
The genetic basis and cell of origin of mixed phenotype acute leukaemia2018
Professor Anthony Moorman
Professor Christine Harrison FRCPath FMedSci
The ribosomal RPL10 R98S mutation drives IRES-dependent BCL-2 translation in T-ALL2018
Professor Anthony Moorman
Professor Julie Irving
Professor James Allan
Professor Christine Harrison FRCPath FMedSci
A genome-wide association study identifies risk loci for childhood acute lymphoblastic leukemia at 10q26.13 and 12q23.12017
Professor Anthony Moorman
Dr Halima Al-shehhi
Acute lymphoblastic leukemia with aleukemic prodrome: Preleukemic dynamics and possible mechanisms of immunosurveillance2017
Dr Lucy Chilton
Professor Christine Harrison FRCPath FMedSci
Daniel Murdy
Professor Anthony Moorman
Clinical relevance of failed and missing cytogenetic analysis in acute myeloid leukaemia2017
Dr Amir Enshaei
Professor Christine Harrison FRCPath FMedSci
Dr Sujith Samarasinghe
Claire Schwab
Professor Anthony Moorman
et al.
Genotype-Specific Minimal Residual Disease Interpretation Improves Stratification in Pediatric Acute Lymphoblastic Leukemia2017
Claire Schwab
Dr Lucy Chilton
Professor Anthony Moorman
Professor Christine Harrison FRCPath FMedSci
Intragenic amplification of PAX5: a novel subgroup in B-cell precursor acute lymphoblastic leukemia?2017
Professor Anthony Moorman
Time for ALL adults to catch up with the children2017
Professor Anthony Moorman
Claire Schwab
Professor Christine Harrison FRCPath FMedSci
Dr Sujith Samarasinghe
Use of minimal residual disease assessment to redefine induction failure in pediatric acute lymphoblastic leukemia2017
Claire Schwab
Sarra Ryan
Dr Lucy Chilton
Alannah Elliott
James Murray
et al.
EBF1-PDGFRB fusion in pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL): genetic profile and clinical implications2016
Professor Anthony Moorman
Professor Christine Harrison FRCPath FMedSci
Acute lymphoblastic leukaemia2016
Dr Lisa Russell
Lisa Jones
Dr Amir Enshaei
Dr Stefano Tonin
Sarra Ryan
et al.
Characterisation of the genomic landscape of CRLF2-rearranged acute lymphoblastic leukemia2016
Professor Anthony Moorman
Claire Schwab
Characterization of leukemias with ETV6-ABL1 fusion2016
Dr Sujith Samarasinghe
Professor Anthony Moorman
Early immature T-ALL as determined by absence of bi-allelic deletion at the TCR gamma locus is not an adverse prognostic factor on the MRC UKALL2003 trial2016
Professor Anthony Moorman
Genomic analyses identify recurrent MEF2D fusions in acute lymphoblastic leukaemia2016
Professor Anthony Moorman
Dr Amir Enshaei
Dr Sujith Samarasinghe
Integrating Genetic Risk Factors with Age, Presenting White Cell Count and MRD Response As Continuous Variables to Predict Relapse in Paediatric Acute Lymphoblastic Leukemia (ALL)2016
Professor Julie Irving
Dr Amir Enshaei
Dr Amy Erhorn
Lynne Minto
Claire Schwab
et al.
Integration of genetic and clinical risk factors improves prognostication in relapsed childhood B-cell precursor acute lymphoblastic leukaemia2016
Professor Anthony Moorman
New and emerging prognostic and predictive genetic biomarkers in B-cell precursor acute lymphoblastic leukemia2016
Claire Schwab
Dr Amir Enshaei
Dr Lisa Russell
Professor Anthony Moorman
The Frequency and Outcome of Ph-like ALL Associated Abnormalities in Childhood Acute Lymphoblastic Leukaemia Treated on MRC UKALL20032016
Dr Sarra Ryan
Elizabeth Matheson
Dr Paul Sinclair
Dr Matthew Bashton
Claire Schwab
et al.
The role of the RAS pathway in iAMP21-ALL2016
Professor Julie Irving
Professor Anthony Moorman
Acute Leukemias of Ambiguous Lineage; Study on 247 Pediatric Patients2015
Dr Al Gabriel
Dr Amir Enshaei
Jennifer Taylor
Dr Amy Erhorn
Claire Schwab
et al.
Age specific incidence of partner gene and secondary abnormalities in MLL positive acute lymphoblastic leukaemia (ALL)2015
Professor Anthony Moorman
Claire Schwab
Karen Marshall
Characterization of Leukemias with ETV6-ABL1 Fusion2015
Dr Lisa Russell
Lisa Jones
Dr Amir Enshaei
Dr Stefano Tonin
Dr Sarra Ryan
et al.
Clincial and Genetic Landscapes Differ Between IGH-CRLF2 and P2RY8-CRLF2 Acute Lymphoblastic Leukaemia2015
Dr Lisa Russell
Lisa Jones
Dr Amir Enshaei
Jamie Rutherford
Dr Stefano Tonin
et al.
Clincial and Genetic Landscapes Differ Between IGH-CRLF2 and P2RY8-CRLF2 Acute Lymphoblastic Leukaemia2015
Professor Anthony Moorman
Professor Julie Irving
Dr Amir Enshaei
Dr Amy Erhorn
Lynne Minto
et al.
Composite Index for Risk Prediction in Relapsed Childhood Acute Lymphoblastic Leukaemia2015
Dr Al Gabriel
Fadhel Alsaid Naji
Dr Ed Schwalbe
Dr Sirintra Nakjang
Dr Simon Cockell
et al.
Epigenetic landscape correlates with genetic subtype but does not predict outcome in childhood acute lymphoblastic leukemia2015
Professor Olaf Heidenreich
Professor Anthony Moorman
Genomic and Drug Response Profiling of Fatal TCF3-HLF-Positive Pediatric Acute Lymphoblastic Leukaemia Identifies Recurrent Mutation Patterns and Novel Therapeutic Options2015
Professor Olaf Heidenreich
Professor Anthony Moorman
Genomics and drug profiling of fatal TCF3-HLF-positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options2015
Professor Anthony Moorman
High Frequency and Poor Outcome of Ph-like Acute Lymphoblastic Leukemia in Adults2015
Dr Amir Enshaei
Professor Anthony Moorman
Professor Christine Harrison FRCPath FMedSci
Dr Sujith Samarasinghe
Integration of Minimal Residual Disease with Other Patient Risk Factors Identifies a Population with Very Poor Overall Survival in Pediatric ALL: Results from the UKALL 2003 Trial2015
Dr Amir Enshaei
Professor Anthony Moorman
Professor Christine Harrison FRCPath FMedSci
Dr Sujith Samarasinghe
Long Term Overall Survival of Greater Than 98% in Childhood ALL Patients with Good Risk Features and Low Risk MRD: Results from a Large Multi-Center Randomized Controlled Trial, UKALL 20032015
Dr Amir Enshaei
Professor Anthony Moorman
Professor Christine Harrison FRCPath FMedSci
Dr Sujith Samarasinghe
Long Term Overall Survival of Greater Than 98% in Childhood ALL Patients with Good Risk Features and Low Risk MRD:A Results from a Large Multi-Center Randomized Controlled Trial, UKALL 20032015
Dr Lucy Chilton
Professor Christine Harrison FRCPath FMedSci
Professor Anthony Moorman
Prognostic Significance and Risk Stratification in Acute Myeloid Leukaemia Patients in the Absence of Successful Cytogenetic Analysis2015
Claire Schwab
Dr Amir Enshaei
Professor Anthony Moorman
Prognostic value of rare IKZF1 deletion in childhood b-cell precursor acute lymphoblastic leukemia: an international collaborative study2015
Professor Anthony Moorman
Relapse in Teenage and Young Adult (TYA) Patients Treated on a Pediatric Minimal Residual Disease (MRD) Stratified Protocol Is Associated with a Poor Outcome: Results from UKALL20032015
Dr Amir Enshaei
Claire Schwab
Dr Lucy Chilton
Professor Christine Harrison FRCPath FMedSci
Professor Anthony Moorman
et al.
Risk Factor Analysis in Paediatric Acute Lymphoblastic Leukaemia with High Hyperdiploidy2015
Dr Amir Enshaei
Claire Schwab
Dr Lucy Chilton
Professor Anthony Moorman
Risk Factor Analysis in Paediatric Acute Lymphoblastic Leukaemia with High Hyperdiploidy2015
Claire Schwab
Alannah Elliott
Dr Lucy Chilton
Professor Anthony Moorman
Professor Christine Harrison FRCPath FMedSci
et al.
Targeted Sequencing Identifies Association Between IL7R-JAK Mutations And Epigenetic Modulators In T-Cell Acute Lymphoblastic Leukemia.2015
Professor Anthony Moorman
Professor Julie Irving
Professor James Allan
Professor Christine Harrison FRCPath FMedSci
The 9p21.3 risk of childhood acute lymphoblastic leukaemia is explained by a rare high-impact variant in CDKN2A2015
Professor Anthony Moorman
Use of Morphological Early Response Data to Predict Relapse in Teenage and Young Adult (TYA) Patients with Acute Lymphoblastic Leukaemia (ALL)2015
Dr Lisa Russell
Dr Amir Enshaei
Lisa Jones
Dr Amy Erhorn
Dr Dino Masic
et al.
IGH@ Translocations Are Prevalent in Teenagers and Young Adults With Acute Lymphoblastic Leukemia and Are Associated With a Poor Outcome2014
Claire Schwab
Dr Amir Enshaei
Professor Anthony Moorman
368 Prognostic Value of Rare IKZF1 deletions in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia: An International Collaborative Study2014
Professor Anthony Moorman
Dr Amir Enshaei
Claire Schwab
Dr Lucy Chilton
Alannah Elliott
et al.
A novel integrated cytogenetic and genomic classification refines risk stratification in pediatric acute lymphoblastic leukemia2014
Professor Anthony Moorman
Acute lymphoblastic leukemia in children with Down syndrome: a retrospective analysis from the Ponte di Legno study group2014
Dr Lucy Chilton
Professor Anthony Moorman
Addition of gemtuzumab ozogamicin to induction chemotherapy in adult patients with acute myeloid leukaemia: a meta-analysis of individual patient data from randomised controlled trials2014
Professor Anthony Moorman
Augmented post-remission therapy for a minimal residual disease-defined high-risk subgroup of children and young people with clinical standard-risk and intermediate-risk acute lymphoblastic leukaemia (UKALL 2003): a randomised controlled trial2014
Professor Anthony Moorman
Dr Tobias Menne
CD20 Expression in Adults with Precursor B-Cell Acute Lymphoblastic Leukemia (B-ALL) from UKALL14, its Regulation by Dexamethasone and Rituximab Induced Cytotoxicity2014
Claire Schwab
Sarra Ryan
Professor Anthony Moorman
Dr Richard McNally
Professor Bryan Young
et al.
Constitutional and somatic rearrangement of chromosome 21 in acute lymphoblastic leukaemia2014
Professor Anthony Moorman
Cytogenetics and outcome of infants with acute lymphoblastic leukemia and absence of MLL rearrangements2014
Professor Anthony Moorman
Does TP53 guard ALL genomes?2014
Claire Schwab
Becca Andrews
Dr Lucy Chilton
Alannah Elliott
Gerald Keil
et al.
EBF1-PDGFRB Fusion in Paediatric Acute Lymphoblastic Leukaemia (ALL): Genetic Profile and Clinical Implications2014
Dr Lucy Chilton
Professor Christine Harrison FRCPath FMedSci
Professor Anthony Moorman
High hyperdiploidy among adolescents and adults with acute lymphoblastic leukaemia (ALL): cytogenetic features, clinical characteristics and outcome2014
Dr Lucy Chilton
Professor Christine Harrison FRCPath FMedSci
Professor Anthony Moorman
Hyperdiploidy with 49-65 chromosomes represents a heterogeneous cytogenetic subgroup of acute myeloid leukemia with differential outcome.2014
Fadhel Alsaid Naji
Dr Vikki Rand
Professor Anthony Moorman
Dr Ed Schwalbe
Dr Amir Enshaei
et al.
Investigation of methylation based biomarkers for prediction of relapse in good prognostic cytogenetic subgroups of childhood acute lymphoblastic leukaemia2014
Claire Schwab
Professor Anthony Moorman
Mouse xenograft modeling of human adult acute lymphoblastic leukemia provides mechanistic insights into adult LIC biology2014
Professor Anthony Moorman
No Evidence That PTEN Abnormalities Impact on Outcome in Pediatric Patients with T-Cell Acute Lymphoblastic Leukemia (T-ALL) Treated on the MRC UKALL2003 Trial2014
Professor Anthony Moorman
Outcome for children and young people with Early T-cell precursor acute lymphoblastic leukaemia treated on a contemporary protocol, UKALL 20032014
Professor Anthony Moorman
Outcome of Central Nervous System Relapses In Childhood Acute Lymphoblastic Leukaemia - Prospective Open Cohort Analyses of the ALLR3 Trial2014
Professor Anthony Moorman
Potential Involvement of Physiological TCR Gamma Delta Clones in Immune Surveillance of Preleukemic Cells2014
Claire Schwab
Dr Amir Enshaei
Professor Anthony Moorman
Prognostic Value of Rare IKZF1 deletions in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia: An International Collaborative Study2014
Claire Schwab
Becca Andrews
Dr Lucy Chilton
Alannah Elliott
Dr Stacey Richardson
et al.
SSBP2-CSF1R Is a Recurrent Fusion in B-Other Acute Lymphoblastic Leukaemia with Variable Clinical Outcome2014
Professor Anthony Moorman
Telomere DNA content and TP53 state provide an insight into genomic instability in older adult patients with all2014
Professor Anthony Moorman
TP53 Alterations Are Frequent in Patients over 60 Years with B-Precursor Acute Lymphoblastic Leukemia (ALL) and Low Hypodiploid/Near Triploid (HoTr) Karyotype; They Correlate with RB1 Deletion and Leukemic Telomere Gain2014
Professor Anthony Moorman
UKALLXII/ECOG2993: addition of imatinib to a standard treatment regimen enhances long-term outcomes in Philadelphia positive acute lymphoblastic leukemia2014
Claire Schwab
Professor Christine Harrison FRCPath FMedSci
Professor Anthony Moorman
BTG1 deletions do not predict outcome in Down syndrome acute lymphoblastic leukemia2013
Dr Halima Al-shehhi
Claire Schwab
Dr Amy Erhorn
Dr Al Gabriel
Professor Christine Harrison FRCPath FMedSci
et al.
Abnormalities of the der(12)t(12;21) in ETV6-RUNX1 acute lymphoblastic leukemia2013
Professor Christine Harrison FRCPath FMedSci
Professor Anthony Moorman
Claire Schwab
Dr Lucy Chilton
An international study of intrachromosomal amplification of chromosome 21 (iAMP21): cytogenetic characterization and outcome2013
Dr Lucy Chilton
Professor Anthony Moorman
Distinct patterns of gained chromosomes in high hyperdiploid acute lymphoblastic leukemia with t(1;19)(q23;p13), t(9;22)(q34;q22) or MLL rearrangements2013
Claire Schwab
Dr Lucy Chilton
Heather Morrison
Lisa Jones
Dr Halima Al-shehhi
et al.
Genes commonly deleted in childhood B-cell precursor acute lymphoblastic leukemia: association with cytogenetics and clinical features2013
Dr Sarah Jenkinson
Professor Anthony Moorman
Impact of NOTCH1/FBXW7 mutations on outcome in pediatric T-cell acute lymphoblastic leukemia patients treated on the MRC UKALL 2003 trial2013
Professor Anthony Moorman
Dr Amir Enshaei
Claire Schwab
Dr Lucy Chilton
Integration Of Cytogenetic and Copy Number Alteration (CNA) Data Into a Single Risk Profile For Paediatric Acute Lymphoblastic Leukaemia (ALL)2013
Dr Amir Enshaei
Claire Schwab
Professor Christine Harrison FRCPath FMedSci
Professor Anthony Moorman
Long-term follow-up of ETV6-RUNX1 ALL reveals that NCI risk, rather than secondary genetic abnormalities, is the key risk factor2013
Professor Anthony Moorman
Professor Christine Harrison FRCPath FMedSci
Loss of chromosomes is the primary event in near-haploid and low-hypodiploid acute lymphoblastic leukemia2013
Professor Anthony Moorman
Claire Schwab
Professor Christine Harrison FRCPath FMedSci
Risk-Directed Treatment Intensification Significantly Reduces the Risk of Relapse Among Children and Adolescents With Acute Lymphoblastic Leukemia and Intrachromosomal Amplification of Chromosome 21: A Comparison of the MRC ALL97/99 and UKALL2003 Trials2013
Professor Anthony Moorman
Dr Lucy Chilton
Dr Amir Enshaei
Professor Christine Harrison FRCPath FMedSci
The clinical characteristics, therapy and outcome of 85 adults with acute lymphoblastic leukemia and t(4;11)(q21;q23)/MLL-AFF1 prospectively treated on UKALLXII/ECOG29932013
Professor Anthony Moorman
Dr Lucy Chilton
Dr Amir Enshaei
Professor Christine Harrison FRCPath FMedSci
The clinical characteristics, therapy and outcome of 85 adults with acute lymphoblastic leukemia and t(4;11)(q21;q23)/MLL-AFF1 prospectively treated in the UKALLXII/ECOG2993 trial2013
Dr Peter Carey
Claire Schwab
Dr Lucy Chilton
Dr Ed Schwalbe
Professor Roderick Skinner
et al.
Treating childhood acute lymphoblastic leukemia in Malawi2013
Dr Lisa Russell
Hannah Ensor
Professor Anthony Moorman
Unravelling the prognostic effect of IKZF1 deletions and IGH@-CRLF2 in adult acute lymphoblastic leukaemia2013
Professor Anthony Moorman
Claire Schwab
Hannah Ensor
Dr Lisa Russell
Heather Morrison
et al.
IGH@ Translocations, CRLF2 Deregulation and Microdeletions in Adolescents and Adults with Acute Lymphoblastic Leukemia2012
Claire Schwab
Dr Lucy Chilton
Dr Amir Enshaei
Heather Morrison
Lisa Jones
et al.
Clinical Relevance of Genes Commonly Deleted in Childhood B-Cell Precursor ALL (BCP-ALL)2012
Professor Anthony Moorman
Dr Amir Enshaei
Dr Lucy Chilton
Claire Schwab
Professor Christine Harrison FRCPath FMedSci
et al.
Delineation of Risk Factors in Paediatric Acute Lymphoblastic Leukaemia with Favourable Cytogenetics2012
Shabnam Thathia
Stuart Ferguson
Hannah Gautrey
Sanne Van Otterdijk
Dr Vikki Rand
et al.
Epigenetic inactivation of TWIST2 in acute lymphoblastic leukemia modulates proliferation, cell survival and chemosensitivity2012
Claire Schwab
Professor Anthony Moorman
Professor Christine Harrison FRCPath FMedSci
Episomal amplification of NUP214-ABL1 fusion gene in B-cell acute lymphoblastic leukemia2012
Claire Schwab
Dr Lucy Chilton
Heather Morrison
Lisa Jones
Dr Halima Al-shehhi
et al.
Genes Commonly Deleted in Childhood B-Cell Precursor ALL (BCP-ALL) Are Associated with Major Cytogenetic Subgroups2012
Professor Anthony Moorman
IKZF1 and 22q11.22 Deletions and PDGFRA Gains Are Associated with Poor Outcome in Down Syndrome Acute Lymphoblastic Leukemia2012
Professor Anthony Moorman
Immunophenotype and Cytogenetic Characteristics in the Relationship Between Birth Weight and Childhood Leukemia2012
Professor Christine Harrison FRCPath FMedSci
Professor Anthony Moorman
Claire Schwab
Intrachromosomal Amplification of Chromosome 21(iAMP21): Cytogenetic Characterisation and Outcome in Childhood B-Cell Precursor Acute Lymphoblastic Leukaemia (BCP-ALL). A Study On Behalf of the Ponte Di Legno International Childhood ALL Workshop2012
Dr Lisa Russell
Claire Schwab
Professor Christine Harrison FRCPath FMedSci
Professor Anthony Moorman
Outcome in children with Down's syndrome and acute lymphoblastic leukemia: role of IKZF1 deletions and CRLF2 aberrations2012
Professor Anthony Moorman
Outcomes in older adults with acute lymphoblastic leukaemia (ALL): results from the international MRC UKALL XII/ECOG2993 trial2012
Professor Anthony Moorman
The clinical relevance of chromosomal and genomic abnormalities in B-cell precursor acute lymphoblastic leukaemia2012
Hannah Ensor
Claire Schwab
Dr Lisa Russell
Professor Christine Harrison FRCPath FMedSci
Professor Anthony Moorman
et al.
Treatment outcome of CRLF2-rearranged childhood acute lymphoblastic leukaemia: a comparative analysis of the AIEOP-BFM and UK NCRI-CCLG study groups2012
Professor Simon Bailey
Professor Roderick Skinner
Dr Peter Carey
Professor Anthony Moorman
Acute lymphoblastic leukarmia (ALL) in Malawi, progress in the first Malawi ALL protocol2011
Professor Anthony Moorman
Acute Lymphoblastic Leukemia in Children with Down Syndrome: A Report From the Ponte Di Legno Study Group2011
Hannah Ensor
Claire Schwab
Dr Lisa Russell
Heather Morrison
Dr Dino Masic
et al.
Demographic, clinical, and outcome features of children with acute lymphoblastic leukemia and CRLF2 deregulation: results from the MRC ALL97 clinical trial2011
Dr Frederik van Delft
Professor Anthony Moorman
Genetic variegation of clonal architecture and propagating cells in leukaemia2011
Dr Vikki Rand
Dr Lisa Russell
Claire Schwab
Hannah Ensor
Professor Julie Irving
et al.
Genomic characterization implicates iAMP21 as a likely primary genetic event in childhood B-cell precursor acute lymphoblastic leukemia2011
Professor Anthony Moorman
Intramuscular PEG-Asparaginase At 1000 U/m(2) Achieves Adequate Trough Activity Levels in the Majority of Patients Treated on the UKALL 2003 Childhood Acute Lymphoblastic Leukemia (ALL) Protocol2011
Professor Anthony Moorman
Mutations in a Large Cohort of Young Adult Patients with Core Binding Factor Acute Myeloid Leukemia: Impact on Outcome and the Selection of Patients for Alternative Treatment Including Transplantation in First Complete Remission2011
Professor Anthony Moorman
Dr Lucy Chilton
Dr Jennifer Wilkinson
Hannah Ensor
Dr Nicholas Bown
et al.
A population-based cytogenetic study of adults with acute lymphoblastic leukemia2010
Professor Anthony Moorman
Dr Lucy Chilton
Dr Jennifer Wilkinson
Hannah Ensor
Natalie Bown
et al.
Age- and sex-adjusted incidence rates of adults with acute lymphoblastic leukemia (ALL) in the northern part of England Response2010
Professor Anthony Moorman
Antigen receptor gene rearrangements reflect on the heterogeneity of adult Acute Lymphoblastic Leukaemia (ALL) with implications of cell-origin of ALL subgroups - a UKALLXII study2010
Professor Christine Harrison FRCPath FMedSci
Professor Anthony Moorman
Cytogenetics of Childhood Acute Myeloid Leukemia: United Kingdom Medical Research Council Treatment Trials AML 10 and 122010
Dr Craig Parker
Dr John Hancock
Professor Anthony Moorman
Mike Morgan
Dr Nicola Green
et al.
Effect of mitoxantrone on outcome of children with first relapse of acute lymphoblastic leukaemia (ALL R3): an open-label randomised trial2010
Professor Anthony Moorman
Imatinib Significantly Enhances Long Term Outcomes In Philadelphia Positive Acute Lymphoblastic Leukaemia, Final Results of the UKALLXII/ECOG2993 Trial2010
Professor Anthony Moorman
Imatinib Significantly Enhances Long-Term Outcomes In Philadelphia Positive Acute Lymphoblastic Leukaemia; Final Results of the UKALLXII/ECOG2993 Trial2010
Professor Anthony Moorman
Minimal residual disease is a significant predictor of treatment failure in non T-lineage adult acute lymphoblastic leukaemia: final results of the international trial UKALL XII/ECOG29932010
Professor Anthony Moorman
Mitoxantrone Improves the Outcome of Children with Central Nervous System (CNS) Involvement at First Relapse of Acute Lymphoblastic Leukemia (ALL)-Results of the International ALLR3 Study2010
Professor Anthony Moorman
Outcome of 1,229 Adult Philadelphia Chromosome Negative B Acute Lyrnphoblastic Leukemia (B ALL) Patients (pts) From the International UKALLXII/E2993 Trial No Difference In Results Between B Cell Immuno phenotypic Subgroups2010
Professor Anthony Moorman
Hannah Ensor
Dr Lucy Chilton
Claire Schwab
Professor Christine Harrison FRCPath FMedSci
et al.
Prognostic effect of chromosomal abnormalities in childhood B-cell precursor acute lymphoblastic leukaemia: results from the UK Medical Research Council ALL97/99 randomised trial2010
Professor Anthony Moorman
Professor Christine Harrison FRCPath FMedSci
Refinement of cytogenetic classification in acute myeloid leukaemia: Determination of prognostic significance of rarer recurring chromosomal abnormalities amongst 5,876 younger adult patients treated in the UK Medical Research Council trials2010
Professor Anthony Moorman
Professor Christine Harrison FRCPath FMedSci
Refinement of cytogenetic classification in acute myeloid leukemia: determination of prognostic significance of rare recurring chromosomal abnormalities among 5876 younger adult patients treated in the United Kingdom Medical Research Council trials2010
Professor Anthony Moorman
Temporal changes in the incidence and pattern of central nervous system relapses in children with acute lymphoblastic leukaemia treated on four consecutive Medical Research Council trials, 1985-20012010
Professor Julie Irving
Professor James Allan
Professor Anthony Moorman
Professor Christine Harrison FRCPath FMedSci
Variation in CDKN2A at 9p21.3 influences childhood acute lymphoblastic leukemia risk2010
Sarina Sulong
Professor Anthony Moorman
Professor Julie Irving
Marian Case
Professor Simon Bailey
et al.
A comprehensive analysis of the CDKN2A gene in childhood acute lymphoblastic leukemia reveals genomic deletion, copy number neutral loss of heterozygosity, and association with specific cytogenetic subgroups2009
Dr Lisa Russell
Professor Olaf Heidenreich
Professor Anthony Moorman
Professor Christine Harrison FRCPath FMedSci
A novel translocation, t(14;19)(q32;p13) involving IGHalpha and the cytokine receptor for erythropoietin2009
Dr Lisa Russell
Professor Olaf Heidenreich
Professor Julie Irving
Professor Anthony Moorman
Heather Morrison
et al.
Deregulated expression of cytokine receptor gene, CRLF2, is involved in lymphoid transformation in B-cell precursor acute lymphoblastic leukemia2009
Professor Anthony Moorman
Dr Michael Griffiths
Dr Tina Davies
Professor Christine Harrison FRCPath FMedSci
Heterogeneous breakpoints in patients with acute lymphoblastic leukemia and the dic(9;20)(p11-13;q11) show recurrent involvement of genes at 20q11.212009
Professor Christine Harrison FRCPath FMedSci
Professor Anthony Moorman
Heterogeneous patterns of amplification of the NUP214-ABL1 fusion gene in T-cell acute lymphoblastic leukemia2009
Professor Anthony Moorman
Dr Michael Griffiths
Professor Julie Irving
Professor Christine Harrison FRCPath FMedSci
Methylation of tumour suppressor gene promoters in the presence and absence of transcriptional silencing in high hyperdiploid acute lymphoblastic leukaemia2009
Dr David Milligan
Professor Anthony Moorman
Prognostic factor analysis of the survival of elderly patients with AML in the MRC AML11 and LRF AML14 trials2009
Professor Anthony Moorman
Professor Christine Harrison FRCPath FMedSci
Prognostic Relevance of Cytogenetics in Childhood Acute Lymphoblastic Leukaemia (ALL): Final Results From MRC ALL972009
Professor Anthony Moorman
Prospective outcome data on 267 unselected adult patients with Philadelphia chromosome-positive acute lymphoblastic leukemia confirms superiority of allogeneic transplantation over chemotherapy in the pre-imatinib era: results from the International ALL Trial MRC UKALLXII/ECOG29932009
Professor Anthony Moorman
Professor Christine Harrison FRCPath FMedSci
Refinement of cytogenetic classification in AML: Determination of prognostic significance of rare recurring chromosomal abnormalities amongst 5635 younger adults treated in the UK MRC Trails2009
Professor Anthony Moorman
T-cell acute lymphoblastic leukemia in adults: clinical features, immunophenotype, cytogenetics, and outcome from the large randomized prospective trial (UKALL XII/ECOG 2993)2009
Dr Vikki Rand
Dr Lisa Russell
Professor Julie Irving
Lisa Jones
Dr Dino Masic
et al.
What Is the Initiating Mechanism of iAMP21 in Childhood B Cell Precursor ALL?2009
Professor Anthony Moorman
Acute leukemia in children with Down's syndrome: the importance of population based study2008
Professor Anthony Moorman
Professor Christine Harrison FRCPath FMedSci
Cytogenetic-specific heterogeneity in the kinetics of minimal residual disease (MIRD) clearance in childhood lymphoblastic leukaemia (ALL)2008
Elizabeth Matheson
Lynne Minto
Professor Anthony Moorman
Dr Andrew Hall
Professor Julie Irving
et al.
Heterogeneous breakpoints target PAX5 in acute lymphoblastic leukaemia patients with dicentric chromosomes2008
Dr Lisa Russell
Professor Anthony Moorman
Professor Olaf Heidenreich
Professor Christine Harrison FRCPath FMedSci
IGH@ Translocations Involving the Pseudoautosomal Region 1 (PAR1) of Both Sex Chromosomes Deregulate the Cytokine Receptor-Like Factor 2 (CRLF2) Gene in B Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL)2008
Professor Anthony Moorman
Sarina Sulong
Professor Julie Irving
Marian Case
Lynne Minto
et al.
Inactivation of CDKN2A in childhood acute lymphoblastic leukaemia (ALL) occurs principally by deletion and is strongly correlated with cytogenetic subgroups2008
Professor Anthony Moorman
One man's dose, another man's poison2008
Professor Anthony Moorman
Standard Consolidation/Maintenance Chemotherapy Is Consistently Superior to a Single Autologous Transplant for Adult Patients with Acute Lymphoblastic Leukemia: Results of the International ALL Trial (MRC UKALL XII/ECOG E2993)2008
Dr Lisa Russell
Professor Anthony Moorman
Professor Christine Harrison FRCPath FMedSci
t(6;14)(p22;q32): a new recurrent IGH@ translocation involving ID4 in B-cell precursor acute lymphoblastic leukemia (BCP-ALL)2008
Marian Case
Dr Tina Davies
Professor Anthony Moorman
Dr Andrew Hall
Professor Julie Irving
et al.
The complex genomic profile of ETV6-RUNX1 positive acute lymphoblastic leukemia highlights a recurrent deletion of TBL1XR12008
Professor Anthony Moorman
Professor Christine Harrison FRCPath FMedSci
The Spectrum and Prognostic Relevance of Additional Abnormalities, Involving 12p and 21q, in Children with ETV6-RUNX1 Positive Acute Lymphoblastic Leukaemia (ALL)2008
Elizabeth Matheson
Professor Anthony Moorman
Dr Andrew Hall
Professor Christine Harrison FRCPath FMedSci
Professor Julie Irving
et al.
Variable breakpoints target PAX5 in patients with dicentric chromosomes: A model for the basis of unbalanced translocations in cancer2008
Dr Frederik van Delft
Professor Anthony Moorman
Professor Christine Harrison FRCPath FMedSci
Genome complexity in acute lymphoblastic leukemia is revealed by array-based comparative genomic hybridization2007
Professor Anthony Moorman
Marian Case
Professor Julie Irving
Dr Andrew Hall
Professor Christine Harrison FRCPath FMedSci
et al.
Genomic profiling reveals multiple genetic targets in ETV6-RUNX1 positive acute lymphoblastic leukaemia (ALL)2007
Professor Christine Harrison FRCPath FMedSci
Professor Anthony Moorman
Intrachromosomal amplification of chromosome 21 (iAMP21) arises from a breakage-fusion-bridge cycle2007
Professor Anthony Moorman
Professor Christine Harrison FRCPath FMedSci
Karyotype is an independent prognostic factor in adult acute lymphoblastic leukaemia (ALL): analysis of cytogenetic data from patients treated on the Medical Research Council (MRC) UKALLXII/Eastern Cooperative Oncology Group (ECOG) 2993 Trial2007
Professor Christine Harrison FRCPath FMedSci
Professor Anthony Moorman
Molecular cytogenetic characterisation of TCF3 (E2A)/19p13 rearrangements in acute lymphoblastic leukaemia2007
Professor Anthony Moorman
Professor Christine Harrison FRCPath FMedSci
Prognosis of children with acute lymphoblastic leukemia (ALL) and intrachromosomal amplification of chromosome 21 (iAMP21)2007
Professor Anthony Moorman
Sequential influences of leukaemia-specific and genetic factors on p-glycoprotein expression in blasts from 817 patients entered into the National Cancer Research Network acute myeloid leukaemia 14 and 15 trials2007
Elizabeth Matheson
Lynne Minto
Professor Anthony Moorman
Dr Andrew Hall
Professor Julie Irving
et al.
Variable Breakpoints Target PAX5 in Patients with Dicentric Chromosomes: A Model for the Basis of Unbalanced Translocations in Cancer2007
Professor Anthony Moorman
Dr Nicholas Bown
Professor Christine Harrison FRCPath FMedSci
PAX5-ETV6 fusion in acute lymphoblastic leukaemia des not define the dic(9;12)2006
Professor Anthony Moorman
Professor Stephen Proctor
Population-based demographic study of karyotypes in 1709 patients with adult acute myeloid leukemia2006
Professor Anthony Moorman
Professor Christine Harrison FRCPath FMedSci
ETV6/RUNX1 fusion at diagnosis and relapse: some prognostic indications2005
Professor Anthony Moorman
Breakpoints of variant 9;22 translocations in chronic myeloid leukemia location preferentially in the CG-richest regions of the genome2005
Professor Anthony Moorman
Professor Christine Harrison FRCPath FMedSci
Derivative chromosome 9 deletions are a significant feature of childhood Philadelphia chromosome positive acute lymphoblastic leukaemia2005
Professor Anthony Moorman
Early response to induction is predictive of survival in childhood Philadelphia chromosome positive acute lymphoblastic leukaemia: results of the Medical Research Council ALL 97 trial2005
Professor Christine Harrison FRCPath FMedSci
Professor Anthony Moorman
Interphase molecular cytogenetic screening for chromosomal abnormalities of prognostic significance in childhood acute lymphoblastic leukaemia: a UK Cancer Cytogenetics Group Study2005
Professor Anthony Moorman
Professor Christine Harrison FRCPath FMedSci
No prognostic effect of additional chromosomal abnormalities in children with acute lymphoblastic leukemia and 11q23 abnormalities2005
Professor Anthony Moorman
Outcome after first relapse in childhood acute lymphoblastic leukaemia: lessons from the United Kingdom R2 trial2005
Professor Anthony Moorman
RAS mutation in acute myeloid leukemia is associated with distinct cytogenetic subgroups but does not influence outcome in patients younger than 60 years2005
Professor Anthony Moorman
Professor Christine Harrison FRCPath FMedSci
Amplification of the ABL gene in T-cell acute lymphoblastic leukemia2004
Professor Christine Harrison FRCPath FMedSci
Professor Anthony Moorman
Comparative expressed sequence hybridization studies of high-hyperdiploid childhood acute lymphoblastic leukemia2004
Professor Christine Harrison FRCPath FMedSci
Professor Anthony Moorman
Is trisomy 5 a distinct cytogenetic subgroup in acute lymphoblastic leukemia?2004
Professor Christine Harrison FRCPath FMedSci
Professor Anthony Moorman
MLL translocations with concurrent 3' deletions: interpretation of FISH results2004
Professor Christine Harrison FRCPath FMedSci
Professor Anthony Moorman
t(14;19)(q32;q13): a recurrent translocation in B-cell precursor acute lymphoblastic leukemia2004
Professor Christine Harrison FRCPath FMedSci
Professor Anthony Moorman
Three distinct subgroups of hypodiploidy in acute lymphoblastic leukaemia2004
Professor Anthony Moorman
Professor Christine Harrison FRCPath FMedSci
Amplification of AML1 in acute lymphoblastic leukemia is associated with a poor outcome2003
Professor Anthony Moorman
Professor Christine Harrison FRCPath FMedSci
Amplification of AML1 on a duplicated chromosome 21 in acute lymphoblastic leukemia: a study of 20 cases2003
Professor Anthony Moorman
Professor Christine Harrison FRCPath FMedSci
Frequency of ETV6/AML1 fusion in adult acute lymphoblastic leukaemia - response to Cuneo et al.2003
Professor Anthony Moorman
Professor Christine Harrison FRCPath FMedSci
Outcome heterogeneity in childhood high-hyperdiploid acute lymphoblastic leukemia2003
Professor Anthony Moorman
Dr Nicholas Bown
Dr Penelope Taylor
Professor Stephen Proctor
Population-based study of unselected acute myeloid leukemia cases reveals distinct cytogenetic pathways analogous to therapy-related AML/MDS2003
Professor Anthony Moorman
Age-specific incidence rates for cytogenetically-defined subtypes of acute myeloid leukaemia2002
Professor Anthony Moorman
Genetic polymorphisms in microsomal epoxide hydrolase and susceptibility to adult acute myeloid leukaemia with defined cytogenetic abnormalities2002
Professor Anthony Moorman
Professor Christine Harrison FRCPath FMedSci
Involvement of the MLL gene in T-lineage acute lymphoblastic leukaemia2002
Professor Anthony Moorman
Patients entered into MRC AML trials are biologically representative of the totality of the disease in the UK2002
Professor Anthony Moorman
Sex ratios and the risks of haematological malignancies2002
Professor Anthony Moorman
Smoking and the risk of acute myeloid leukaemia in cytogenetic subgroups2002
Richard Feltbower
Professor Anthony Moorman
Incidence of childhood acute lymphoblastic leukaemia in Yorkshire, UK2001
Professor Anthony Moorman
Karyotype and age in acute myeloid leukaemia: are they linked?2001
Professor James Allan
Professor Anthony Moorman
Polymorphism in glutathione S-transferase PI is associated with susceptibility to chemotherapy-induced leukaemia2001
Professor Anthony Moorman
Professor Christine Harrison FRCPath FMedSci
Monosomy 20 as a pointer to dicentric (9;20) in acute lymphoblastic leukaemia2000
Professor Christine Harrison FRCPath FMedSci
Professor Anthony Moorman
Emeritus Professor Alan Craft
Dr Juliet Hale
Dr Jennifer Kernahan
et al.
The United Kingdom Childhood Cancer Study: objectives, materials and methods2000
Professor Anthony Moorman
Derivative chromosomes of 11q23-translocations in hematologic malignancies1998
Professor Anthony Moorman
Hematologic malignancies with t(4;11)(q21;q23) - a cytogenetic, morphologic, immunophenotypic, and clinical study of 183 cases1998
Professor Anthony Moorman
Hematological malignancies with a deletion of 11q23: cytogenetic and clinical aspects1998
Professor Anthony Moorman
Hematological malignancies with t(9;11)(p21-22;q23) - a laboratory and clinical study of 125 cases1998
Professor Anthony Moorman
Myelodysplastic syndromes associated with 11q23 abnormalities1998
Professor Anthony Moorman
Secondary acute leukaemia and myelodysplastic syndrome with 11q23 abnormalities1998
Professor Christine Harrison FRCPath FMedSci
Professor Anthony Moorman
Ten novel 11q23 chromosomal partner sites1998
Professor Anthony Moorman
The t(10;11)(p12;q23) translocation in acute leukemia: a cytogenetic and clinical profile of 20 patients1998
Professor Anthony Moorman
The t(6;11)(q27;q23) translocation in acute leukemia: a laboratory and clinical study of 30 cases1998
Professor Anthony Moorman
The translocations, t(11;19)(q23;p13.1) and t(11;19)(q23;p13.3): a cytogenetic and clinical profile of 53 patients1998
Professor Anthony Moorman
Isochromosomes in acute lymphoblastic leukaemia: i(21q) is a significant finding1996
Professor Anthony Moorman
Probes for hidden hyperdiploidy in acute lymphoblastic leukaemia1996
Professor Anthony Moorman
Complex hyperdiploidy in acute myeloid leukaemia: a United Kingdom Cancer Cytogenetics Group Study1995
Professor Anthony Moorman
Association of 17p loss with late-stage or refractory disease in hematologic malignancy1994