Claire Schwab Dr Ruth Cranston Dr Sarra Ryan Ellie Butler Emily Winterman et al. | Integrative genomic analysis of childhood acute lymphoblastic leukaemia lacking a genetic biomarker in the UKALL2003 clinical trial | 2023 |
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Dr Tom Creasey Emilio Barretta Dr Sarra Ryan Ellie Butler Dr Daniel Leongamornlert et al. | Genetic and genomic analysis of acute lymphoblastic leukaemia in older adults reveals a distinct profile of abnormalities: analysis of 210 patients from the UKALL14 and UKALL60+ clinical trials | 2022 |
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Claire Schwab Daniel Murdy Ellie Butler Dr Amir Enshaei Emily Winterman et al. | Genetic characterisation of childhood B-other-acute lymphoblastic leukaemia in UK patients by fluorescence in situ hybridisation and Multiplex Ligation-dependent Probe Amplification | 2022 |
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Dr Matthew Bashton Robin Hollis Dr Sarra Ryan Claire Schwab Professor Christine Harrison FRCPath FMedSci et al. | Concordance of copy number abnormality detection using SNP arrays and Multiplex Ligation-dependent Probe Amplification (MLPA) in acute lymphoblastic leukaemia | 2020 |
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Dr Paul Sinclair Dr Sarra Ryan Dr Matthew Bashton Shaun Hollern Rebecca Hanna et al. | SH2B3 inactivation through CN-LOH-12q is uniquely associated with B-cell precursor ALL with iAMP21 or other chromosome 21 gain | 2019 |
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Dr Paul Sinclair Dr Helen Blair Dr Sarra Ryan Dr Lars Buechler Joanna Cheng et al. | Dynamic clonal progression in xenografts of acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 21 | 2018 |
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Dr Janet Lindsey Dr Rebecca Hill Dr Ed Schwalbe Dr Christopher Howell Dr Reza Rafiee et al. | Molecular and Prognostic Heterogeneity within MYC and MYCN Amplified Medulloblastomas | 2016 |
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Dr Sarra Ryan Elizabeth Matheson Dr Paul Sinclair Dr Matthew Bashton Claire Schwab et al. | The role of the RAS pathway in iAMP21-ALL | 2016 |
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Dr Paul Sinclair Joanna Cheng Prahlad Raninga Rebecca Hanna Shaun Hollern et al. | A Targeted Functional Clone Tracking Assay for the Identification of Tumour Suppressor Genes in BCP- ALL Implicates the Transcription Factors FOXO3 and PRDM1 | 2015 |
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Dr Lisa Russell Lisa Jones Dr Amir Enshaei Jamie Rutherford Dr Stefano Tonin et al. | Clincial and Genetic Landscapes Differ Between IGH-CRLF2 and P2RY8-CRLF2 Acute Lymphoblastic Leukaemia | 2015 |
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Dr Lisa Russell Lisa Jones Dr Amir Enshaei Dr Stefano Tonin Dr Sarra Ryan et al. | Clincial and Genetic Landscapes Differ Between IGH-CRLF2 and P2RY8-CRLF2 Acute Lymphoblastic Leukaemia | 2015 |
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Claire Schwab Dr Sarra Ryan Professor Christine Harrison FRCPath FMedSci
| Constitutional and somatic rearrangement of chromosome 21 in acute lymphoblastic leukaemia | 2014 |
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Claire Schwab Becca Andrews Dr Lucy Chilton Alannah Elliott Gerald Keil et al. | EBF1-PDGFRB Fusion in Paediatric Acute Lymphoblastic Leukaemia (ALL): Genetic Profile and Clinical Implications | 2014 |
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Dr Rebecca Hill Dr Janet Lindsey Dr Ed Schwalbe Dr Daniel Williamson Dr Sarra Ryan et al. | MYC and TP53 defects emerge and interact at medulloblastoma relapse, define rapidly progressive disease and can be targeted therapeutically | 2014 |
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Dr Rebecca Hill Dr Janet Lindsey Dr Ed Schwalbe Dr Karen Barker Dr Daniel Williamson et al. | MYC and TP53 defects interact at medulloblastoma relapse to define rapidly progressive disease and can be targeted therapeutically | 2014 |
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Jake Clayton Joanna Cheng Dr Sarra Ryan Professor Christine Harrison FRCPath FMedSci Dr Paul Sinclair et al. | Oncogenomic Screening Strategies to Identify Tumour Suppressor Genes on Chromosome 12 in Acute Myeloid Leukaemia | 2014 |
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Claire Schwab Becca Andrews Dr Lucy Chilton Alannah Elliott Dr Stacey Richardson et al. | SSBP2-CSF1R Is a Recurrent Fusion in B-Other Acute Lymphoblastic Leukaemia with Variable Clinical Outcome | 2014 |
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Dr Sarra Ryan Dr Ed Schwalbe Mike Cole Yuan Lu Dr Meryl Lusher et al. | MYC family amplification and clinical risk-factors interact to predict an extremely poor prognosis in childhood medulloblastoma | 2012 |
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Professor David Ellison Dr Hisham Megahed Dr Meryl Lusher Dr Sarra Ryan Professor Simon Bailey et al. | Definition of Disease-Risk Stratification Groups in Childhood Medulloblastoma Using Combined Clinical, Pathologic, and Molecular Variables | 2011 |
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Dr Vikki Rand Dr Lisa Russell Claire Schwab Hannah Ensor Professor Julie Irving et al. | Genomic characterization implicates iAMP21 as a likely primary genetic event in childhood B-cell precursor acute lymphoblastic leukemia | 2011 |
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Dr Ed Schwalbe Dr Janet Lindsey Debbie Straughton Mike Cole Dr Hisham Megahed et al. | Rapid Diagnosis of Medulloblastoma Molecular Subgroups | 2011 |
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Dr Sarra Ryan Dr Vikki Rand Claire Schwab Heather Morrison Elizabeth Matheson et al. | Ras Signalling Pathway and Novel Target Genes Related to Down Syndrome Contribute to the Development of B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) in iAMP21 Patients | 2011 |
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Dr Hisham Megahed Dr Sarra Ryan Dr Meryl Lusher Sarah Nicholson Professor Simon Bailey et al. | Clinical, Pathological, and Molecular Variables Define Risk-Stratification Groups in Childhood Medulloblastoma | 2010 |
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Professor David Ellison Dr Hisham Megahed Dr Sarra Ryan Dr Meryl Lusher Sarah Nicholson et al. | Clinical, pathological, and molecular variables define risk-stratification groups in childhood medulloblastoma | 2010 |
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Claire Schwab Lisa Jones Heather Morrison Dr Sarra Ryan Professor Christine Harrison FRCPath FMedSci et al. | Evaluation of Multiplex Ligation-Dependent Probe Amplification as a Method for the Detection of Copy Number Abnormalities in B-Cell Precursor Acute Lymphoblastic Leukemia | 2010 |
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Dr James Hayden Dr Matthew Allen Dr Sarra Ryan Sarah Nicholson Dr Ed Schwalbe et al. | Molecular Mechanisms in Supratentorial CNS-PNET development | 2010 |
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Professor Steven Clifford Dr Sarra Ryan Mike Cole Dr Meryl Lusher Kieran O'Toole et al. | MYC gene family amplification and expression in childhood medulloblastoma: Biological significance and utility for high-risk disease stratification | 2010 |
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Dr Sarra Ryan Professor David Elliott Professor David Ellison Professor Simon Bailey Professor Steven Clifford et al. | Amplification and overexpression of Hsa-miR-3ob, Hsa-miR-30d and KHDRBS3 at 8q24.22-q24.23 in medulloblastoma | 2009 |
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