Publications by Professor Brendan Kenny - ePrints

Browsing publications by Professor Brendan Kenny.

Newcastle Authors	Title	Year
Dr Paul Dean Sabine Quitard Dr David Bulmer Professor Brendan Kenny	Cultured enterocytes internalise bacteria across their basolateral surface for, pathogen-inhibitable, trafficking to the apical compartment	2015
Professor Brendan Kenny	Nck adaptors, besides promoting N-WASP mediated actin-nucleation activity at pedestals, influence the cellular levels of enteropathogenic Escherichia coli Tir effector	2014
Dr Paul Dean Professor Brendan Kenny	A bacterial encoded protein induces extreme multinucleation and cell-cell internalization in intestinal cells	2013
Professor Brendan Kenny Dr Paul Dean	Do Caco-2 subclones provide more appropriate in vitro models for understanding how human enteric pathogens cause disease?	2013
Dr Paul Dean Lorna Young Sabine Quitard Professor Brendan Kenny	Insights into the Pathogenesis of Enteropathogenic E. coli Using an Improved Intestinal Enterocyte Model	2013
Dr Paul Dean Professor Brendan Kenny	Cell-surface nucleolin is sequestered into EPEC microcolonies and may play a role during infection	2011
Dr Marie-Helene Ruchaud Professor Brendan Kenny	Proteasome-independent degradation of canonical NFκB complex components by the NleC protein of pathogenic Escherichia coli	2011
Dr Marie-Helene Ruchaud Dr Paul Dean Professor Brendan Kenny	The Enteropathogenic E. coli (EPEC) Tir Effector Inhibits NF-κB Activity by Targeting TNFα Receptor-Associated Factors	2011
Professor Brendan Kenny	PKA-mediated phosphorylation of EPEC-Tir at serine residues 434 and 463: A novel pathway in regulating Rac1 GTPase function	2010
Dr Paul Dean Sabine Quitard Professor Brendan Kenny	The bacterial effectors EspG and EspG2 induce a destructive calpain activity that is kept in check by the co-delivered Tir effector	2010
Dr Paul Dean Jonathan Scott Andy Knox Sabine Quitard Dr Nick Watkins et al.	The Enteropathogenic E. coli Effector EspF Targets and Disrupts the Nucleolus by a Process Regulated by Mitochondrial Dysfunction	2010
Dr David Saunders Dr Paul Dean Professor Brendan Kenny Judith Parkhill	Complete Genome Sequence and Comparative Genome Analysis of Enteropathogenic Escherichia coli O127:H6 Strain E2348/69	2009
Professor Brendan Kenny	Dual infection system identifies a crucial role for PKA-mediated serine phosphorylation of the EPEC-Tir-injected effector protein in regulating Rac1 function	2009
Professor Brendan Kenny	Host-microbe interactions: bacteria	2009
Dr Paul Dean Professor Brendan Kenny	The effector repertoire of enteropathogenic E-coli: ganging up on the host cell	2009
Professor Brendan Kenny	Dual infection of mammalian cells provides novel insights into injected bacterial effector protein function	2008
Dr Marie-Helene Ruchaud Professor Brendan Kenny	Enteropathogenic Escherichia coli (EPEC) inactivate innate immune responses prior to compromising epithelial barrier function	2007
Professor Brendan Kenny	Tir phosphorylation and Nck/N-WASP recruitment by enteropathogenic and enterohaemorrhagic Escherichia coli during ex vivo colonization of human intestinal mucosa is different to cell culture models	2007
Dr Paul Dean Professor Brendan Kenny	Potent diarrheagenic mechanism mediated by the cooperative action of three enteropathogenic Escherichia coli-injected effector proteins	2006
Professor Brendan Kenny	The enteropathogenic Escherichia coli (EPEC) Map effector is imported into the mitochondrial matrix by the TOM/Hsp70 system and alters organelle morphology	2006
Sabine Quitard Dr Paul Dean Professor Brendan Kenny	The enteropathogenic Escherichia coli EspF effector molecule inhibits PI-3 kinase-mediated uptake independently of mitochondrial targeting	2006
Dr David Miller Sabine Quitard Dr Paul Dean Professor Brendan Kenny	Enteropathogenic Escherichia coli (EPEC) effector-mediated suppression of antimicrobial nitric oxide production in a small intestinal epithelial model system	2005
Dr Paul Dean Professor Brendan Kenny	EPEC's weapons of mass subversion	2005
Dr Paul Dean Professor Brendan Kenny	Intestinal barrier dysfunction by enteropathogenic Escherichia coli is mediated by two effector molecules and a bacterial surface protein	2004
Professor Brendan Kenny	CesT is a bivalent enteropathogenic Escherichia coli chaperone required for translocation of both Tir and Map	2003
Dr Mark Banfield Dr David Scott Professor Brendan Kenny	Effect of protein kinase-A mediated phosphorylation on the structure and association properties of the enteropathogenic Escherichia coli Tir virulence protein	2003
Professor Brendan Kenny	Enteropathogenic Escherichia coli (EPEC) and its effector molecules	2003
Dr Sonia Pellegrini Professor Brendan Kenny	Synergistic roles for the Map and Tir effector molecules in mediating uptake of enteropathogenic Escherichia coli (EPEC) into non-phagocytic cells	2003
Professor Brendan Kenny	Co-ordinate regulation of distinct host signalling pathways by multifunctional enteropathogenic Escherichia coli effector molecules	2002
Professor Brendan Kenny	Enteropathogenic E. coli - a crafty subversive little bug	2002
Professor Brendan Kenny	Mechanism of action of EPEC Type III effector molecules	2002
Professor Brendan Kenny	Enteropathogenic Escherichia coli (EPEC) Tir Receptor Molecule Does Not Undergo Full Modification When Introduced into Host Cells by EPEC-Independent Mechanisms	2001
Professor Brendan Kenny	Phosphoserine modification of the enteropathogenic Escherichia coli Tir molecule is required to trigger conformational changes in Tir and efficient pedestal elongation	2001
Professor Brendan Kenny	Role of sipA in the early stages of Salmonella typhimurium entry into epithelial cells	2001
Professor Brendan Kenny	The enterohaemorrhagic E. coli (serotype O157:H7) Tir molecule is not functionally interchangeable for its enteropathogenic E. coli (serotype O127:H6) homologue	2001
Professor Brendan Kenny	Targeting of an enteropathogenic Escherichia coli (EPEC) effector protein to host mitochondria	2000
Professor Brendan Kenny	Enteropathogenic Escherichia coli inhibits phagocytosis	1999
Professor Brendan Kenny	Enteropathogenic Escherichia coli inhibits phagocytosis	1999
Professor Brendan Kenny	Type III secretion-dependent haemolytic activity of enteropathogenic Escherichia coli (EPEC)	1999