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Browsing publications by Professor Neil Perkins.

Newcastle AuthorsTitleYearFull text
Liam Spencer
Dr Darren Flynn
Dr Gregory Maniatopoulos
Dr James Newham
Professor Neil Perkins
et al.
The implementation of whole-school approaches to transform mental health in UK schools: A realist evaluation protocol2022
Dr Jill Hunter
Lucy Salmon
Dr Caroline Wilson
Professor Neil Perkins
Dr Owen Davies
et al.
Centrosome dysfunction associated with somatic expression of the synaptonemal complex protein TEX122021
Dr Shelina Visram
Emeritus Professor David Hunter
Professor Neil Perkins
Rebecca Finn
Health and Wellbeing Boards as theatres of accountability: A dramaturgical analysis2021
Dr Ling-I Su
Emma Corbin
Professor Neil Perkins
Temporal modulation of the NF-B RelA network in response to different types of DNA damage2021
Dr Gema Dura
Dr Daniel Peters
Dr Helen Waller
Dr Adrian Yemm
Professor Neil Perkins
et al.
A thermally reformable protein polymer2020
Anna Smith
Dr Julia Whitehall
Carla Bradshaw
Dr Fiona Robertson
Dr Alasdair Blain
et al.
Age-associated mitochondrial DNA mutations cause metabolic remodeling that contributes to accelerated intestinal tumorigenesis2020
Dr Iglika Ivanova
Professor Neil Perkins
Hypoxia induces rapid, STAT3 and ROS dependent, mitochondrial translocation of RelA(p65) and IκBα2019
Majeed Al-Jawdah
Dr Iglika Ivanova
Dr Helen Waller
Professor Neil Perkins
Professor Jeremy Lakey
et al.
Induction of the immunoprotective coat of Yersinia pestis at body temperature is mediated by the Caf1R transcription factor2019
Dr Katarzyna Szoltysek
Dr Simon Cockell
Professor Neil Perkins
RRAD, IL4I1, CDKN1A, and SERPINE1 genes are potentially co-regulated by NF-κB and p53 transcription factors in cells exposed to high doses of ionizing radiation2018
Professor Neil Perkins
More than just an IκB kinase: the IKK complex coordinates mRNA stability and transcription2018
Dr Anna Moles Fernandez
Dr Jacqueline Butterworth
Dr Jill Hunter
Dr Jack Leslie
Helene Sellier
et al.
A RelA(p65) Thr505 phospho-site mutation reveals an important mechanism regulating NF-kB dependent liver regeneration and cancer2016
Dr Jill Hunter
Jack Leslie
Professor Neil Perkins
c-Rel and its many roles in cancer: an old story with new twists2016
Dr Tyrell Cartwright
Professor Neil Perkins
Dr Caroline Wilson
NFKB1: a suppressor of inflammation, ageing and cancer2016
Dr Jill Hunter
Professor Neil Perkins
The clinical development candidate CCT245737 is an orally active CHK1 inhibitor with preclinical activity in RAS mutant NSCLC and Eμ-MYC driven B-cell lymphoma2016
Dr Jill Hunter
Dr Jacqueline Butterworth
Helene Sellier
Huw Thomas
Dr Christopher Bacon
et al.
The NF-κB subunit c-Rel regulates Bach2 tumour suppressor expression in B-cell lymphoma2016
Dr Anna Moles Fernandez
Dr Jacqueline Butterworth
Dr Jill Hunter
Professor Derek Mann
Professor Fiona Oakley
et al.
Mutation of Rela THR505 Enhances Liver Regeneration Following Partial Hepatectomy2015
Dr Elaine Willmore
Dr Aaron Ions Gardner
Dr Susan Tudhope
Belinda Murtani
Jessica Caffry
et al.
Novel small molecule IKK alpha inhibitors inhibit non- canonical NF-kappa B signaling and survival of primary CLL cells2015
Professor Neil Perkins
The importance of the p50 NF-κB subunit2015
Dr Anna Moles Fernandez
Dr Jacqueline Butterworth
Dr Jill Hunter
Dr Dina Tiniakos
Professor Derek Mann
et al.
Thr505 RelA phosphorylation controls liver proliferative response and supresses NF-kappa B tumor-promoting activities2015
Dr Adeline Ledoux
Dr Jill Hunter
Professor Neil Perkins
Endothelial-cell FAK targeting sensitizes tumours to DNA-damaging therapy2014
Professor Neil Perkins
Identification of New Mechanisms of Cellular Response to Chemotherapy by Tracking Changes in Post-Translational Modifications by Ubiquitin and Ubiquitin-Like Proteins2014
Dr Adeline Ledoux
Professor Neil Perkins
NF-kB and the cell cycle2014
Professor Neil Perkins
NF-kappa B is a critical mediator of BRCA1-induced chemoresistance2014
Dr Alessio Iannetti
Dr Adeline Ledoux
Dr Susan Tudhope
Helene Sellier
Adam Moore
et al.
Regulation of p53 and Rb Links the Alternative NF-kappaB Pathway to EZH2 Expression and Cell Senescence2014
Dr Jill Hunter
Dr Jacqueline Butterworth
Professor Neil Perkins
Professor Melissa Bateson
Dr Claire Richardson
et al.
Using body temperature, food and water consumption as biomarkers of disease progression in mice with Eμ-myc lymphoma2014
Professor Neil Perkins
Emerging from NF-kappa B's Shadow, SUMOylated I kappa B alpha Represses Transcription2013
Professor Neil Perkins
Friend or foe: emerging role of nuclear factor kappa-light-chain-enhancer of activated B cells in cell senescence2013
Professor Neil Perkins
Identification and Functional Characterization of FMN2, a Regulator of the Cyclin-Dependent Kinase Inhibitor p212013
Dr Lindsay Murphy
Dr Saimir Luli
Dr Lee Borthwick
Dr Steven O'Reilly
Professor Neil Perkins
et al.
Inhibition of RelA-Ser536 phosphorylation by a competing peptide reduces mouse liver fibrosis without blocking the innate immune response2013
Dr Adeline Ledoux
Helene Sellier
Dr Alessio Iannetti
Professor Neil Perkins
NF kappa B regulates expression of Polo-like kinase 42013
Dr Renee Johnson
Professor Neil Perkins
Regulation of Rad50 dependent DNA repair by the RelA(p65) NF-kB subunit2012
Professor Fiona Oakley
Professor Neil Perkins
BAG-1 interacts with the p50-p50 homodimeric NF-kappa B complex: implications for colorectal carcinogenesis2012
Professor Neil Perkins
Cysteine 38 Holds the Key to NF-kappa B Activation2012
Dr Renee Johnson
Professor Neil Perkins
Nuclear factor-kappa B, p53, and mitochondria: regulation of cellular metabolism and the Warburg effect2012
Professor Neil Perkins
The diverse and complex roles of NF-kappa B subunits in cancer.2012
Dr Renee Johnson
Professor Neil Perkins
p53-dependent regulation of mitochondrial energy production by the RelA subunit of NF-κB2011
Professor Neil Perkins
Dr Renee Johnson
The role of RelA (p65) threonine 505 phosphorylation in the regulation of cell growth, survival, and migration2011
Professor Neil Perkins
p53-dependent repression of polo-like kinase-1 (PLK1)2010
Professor Neil Perkins
Regulation of cyclin D1 gene expression2010
Professor Neil Perkins
Thr(435) phosphorylation regulates RelA (p65) NF-kappa B subunit transactivation2010
Professor Neil Perkins
[abstract] Regulation of cancer cell proliferation and survival by NF-kappa B2009
Professor Neil Perkins
Getting away from it all in Capri: the 2008 EMBO workshop on NF-kappa B2009
Professor Neil Perkins
A238L inhibits NF-ATc2, NF-kappa B, and c-Jun activation through a novel mechanism involving protein kinase C-theta-mediated up-regulation of the amino-terminal transactivation domain of p3002008
Professor Neil Perkins
IEX-1 directly interferes with RelA/p65 dependent transactivation and regulation of apoptosis2008
Professor Neil Perkins
Regulation of cyclin D1 RNA stability by SNIP12008
Professor Neil Perkins
Regulation of the ReIA (p65) transactivation domain2008
Professor Neil Perkins
Integrating cell-signalling pathways with NF-kappaB and IKK function2007
Professor Neil Perkins
p53 and NF-κB crosstalk: IKKα tips the balance2007
Professor Neil Perkins
Proenkephalin assists stress-activated apoptosis through transcriptional repression of NF-kappaB- and p53-regulated gene targets2007
Professor Neil Perkins
Regulation of ATR-dependent pathways by the FHA domain containing protein SNIP12007
Professor Neil Perkins
Transcriptional profiling of the LPS induced NF-κB response in macrophages2007
Professor Neil Perkins
Cisplatin mimics ARF tumor suppressor regulation of RelA (p65) nuclear factor-kappaB transactivation2006
Professor Neil Perkins
Differential regulation of NF-κB activation and function by topoisomerase II inhibitors2006
Professor Neil Perkins
Good cop, bad cop: the different faces of NF-kappaB2006
Professor Neil Perkins
Post-translational modifications regulating the activity and function of the nuclear factor kappa B pathway2006
Professor Neil Perkins
Regulation of p53 tumour suppressor target gene expression by the p52 NF-kappaB subunit2006
Professor Neil Perkins
SNIP1 is a candidate modifier of the transcriptional activity of c-Myc on E box-dependent target genes2006
Professor Neil Perkins
ARF the integrator: linking NF-kappaB, p53 and checkpoint kinases2005
Professor Neil Perkins
Cyclin D1 represses p300 transactivation through a cyclin-dependent kinase-independent mechanism2005
Professor Neil Perkins
Differential regulation of c-Jun-dependent transcription by SUMO-specific proteases2005
Professor Neil Perkins
p21(WAF1/CIP1) regulates the p300 sumoylation motif CRD1 through a C-terminal domain independently of Cyclin/CDK binding2005
Professor Neil Perkins
Regulation of NF-kappaB and p53 through activation of ATR and Chk1 by the ARF tumour suppressor2005
Professor Neil Perkins
Regulation of NF-kappaB function2005
Professor Neil Perkins
SIRT1 deacetylation and repression of p300 involves lysine residues 1020/1024 within the cell cycle regulatory domain 12005
Professor Neil Perkins
The DEAD box protein p68: a novel transcriptional coactivator of the p53 tumour suppressor2005