Publications by Dr James Garnett - ePrints

Browsing publications by Dr James Garnett.

Newcastle Authors	Title	Year
Dr James Garnett	Differentiation of Human Induced Pluripotent Stem Cells from Patients with Severe COPD into Functional Airway Epithelium	2022
Dr James Garnett	An EZH2-dependent transcriptional complex promotes aberrant epithelial remodelling after injury	2021
Catherine Hatton Dr Rachel Botting Dr Maria Duenas Fadic Dr Iram Haq Dr Bernard Verdon et al.	Delayed induction of type I and III interferons mediates nasal epithelial cell permissiveness to SARS-CoV-2	2021
Dr Emily Mavin Dr Bernard Verdon Sean Carrie Dr Vinciane Saint-Criq Jason Powell et al.	Real-time measurement of cellular bioenergetics in fully differentiated human nasal epithelial 2 cells grown at air-liquid-interface	2020
Dr James Garnett	Recapitulating idiopathic pulmonary fibrosis related alveolar epithelial dysfunction in a human iPSC‐derived air‐liquid interface model	2020
Dr James Garnett	Effective glucose metabolism maintains low intracellular glucose in airway epithelial cells after exposure to hyperglycemia	2019
Jason Powell Dr James Garnett Dr Michael Mather Dr Faye Cooles Dr Bernard Verdon et al.	Excess Mucin Impairs Subglottic Epithelial Host Defense in Mechanically Ventilated Patients	2018
Dr James Garnett	Metformin attenuates the effect of Staphylococcus aureus on airway tight junctions by increasing PKCζ-mediated phosphorylation of occludin	2018
Salam Ibrahim Mark Turner Dr Vinciane Saint-Criq Dr James Garnett Dr Iram Haq et al.	CK2 is a key regulator of SLC₄A2- mediated Cl-/HCO₃- exchange in human airway epithelia	2017
Dr Iram Haq Dr Michael Gray Dr James Garnett Professor Christopher Ward Dr Malcolm Brodlie et al.	Airway surface liquid homeostasis in cystic fibrosis: pathophysiology and therapeutic targets	2016
Mark Turner Dr Vinciane Saint-Criq Waseema Patel Salam Ibrahim Dr Burns Verdon et al.	Hypercapnia Modulates cAMP Signalling and Cystic Fibrosis Transmembrane Conductance Regulator-dependent Anion and Fluid Secretion in Airway Epithelia	2016
Dr James Garnett Dr Georgina Carr Jason Powell Dr Malcolm Brodlie Professor Christopher Ward et al.	Hyperglycaemia and Pseudomonas aeruginosa acidify cystic fibrosis airway surface liquid by elevating epithelial monocarboxylate transporter 2 dependent lactate-H⁺ secretion	2016
Dr James Garnett	Increased airway glucose increases airway bacterial load in hyperglycaemia	2016
Dr Georgina Carr Dr James Garnett	Metformin prevents the effects of Pseudomonas aeruginosa on airway epithelial tight junctions and restricts hyperglycaemia-induced bacterial growth	2016
Jason Powell Dr James Garnett Dr Bernard Verdon Emerita Professor Janet Wilson Professor Jeffrey Pearson et al.	A Human in Vitro Model of the Subglottic Airway	2015
Dr James Garnett Dr Michael Gray Dr Malcolm Brodlie Professor Christopher Ward	Airway epithelial cells secrete bicarbonate in response to acidic by-products of pseudomonas aeruginosa metabolism	2015
Dr James Garnett	A novel fluorescent sensor protein for detecting changes in airway surface liquid glucose concentration	2014
Dr James Garnett	Fructose transport-deficient Staphylococcus aureus reveals important role of epithelial glucose transporters in limiting sugar-driven bacterial growth in airway surface liquid	2014
Dr James Garnett	SPLUNC1: link between acidity and dehydration of the airway surface liquid in CF	2014
Dr James Garnett Mark Turner	Controversies surrounding the role of CFTR in airway bicarbonate secretion	2013
Dr James Garnett Dr Michael Gray Dr Malcolm Brodlie Professor Christopher Ward Erin Baker et al.	Elevated Paracellular Glucose Flux across Cystic Fibrosis Airway Epithelial Monolayers Is an Important Factor for Pseudomonas aeruginosa Growth	2013
Dr James Garnett	Metformin reduces airway glucose permeability and hyperglycaemia-induced Staphylococcus aureus load independently of effects on blood glucose	2013
Dr James Garnett Hui Tunkamnerdthai Dr Michael Gray	Protein phosphatase 1 coordinates CFTR-dependent airway epithelial HCO₃- secretion by reciprocal regulation of apical and basolateral membrane Cl--HCO₃- exchangers	2013
Dr James Garnett Erin Baker	Proinflammatory mediators disrupt glucose homeostasis in airway surface liquid	2012
Dr James Garnett Erin Baker	Sweet talk: insights into the nature and importance of glucose transport in lung epithelium	2012
Dr James Garnett Dr Michael Gray	Novel Role for Pendrin in Orchestrating Bicarbonate Secretion in Cystic Fibrosis Transmembrane Conductance Regulator (CFTR)-expressing Airway Serous Cells	2011
Dr Simon Peacock Dr Robert Shiel Dr James Garnett	Ecological mechanisms affecting the restoration of diversity in agriculturally improved meadow grassland. Colonisation of plant roots by arbuscular mycorrhizas in upland meadow grasslands:correlations with management and plant phosphorus status	2001