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Browsing publications by Philip Griffiths.

Newcastle AuthorsTitleYearFull text
Philip Griffiths
Dr Fiona Smith
Dr Michael Firbank
Professor Grainne Gorman
Professor Robert Taylor
et al.
Chronic progressive external ophthalmoplegia - Disease mechanisms and clinical outcome measures2013
Dr Cynthia Yu Wai Man
Dr Fiona Smith
Dr Michael Firbank
Professor Grainne Gorman
Professor Robert Taylor
et al.
Extraocular Muscle Atrophy and Central Nervous System Involvement in Chronic Progressive External Ophthalmoplegia2013
Dr Patrick Yu Wai Man
Nwanyieze Nwali
Philip Griffiths
Professor Patrick Chinnery
Idebenone treatment for Leber hereditary optic neuropathy - Past, present, and future2013
Dr Patrick Yu Wai Man
Dr Bas Buchner
Nwanyieze Nwali
Philip Griffiths
Professor Patrick Chinnery
et al.
Persistence of the treatment effect of idebenone in Leber's hereditary optic neuropathy2013
Anais Thouin
Philip Griffiths
Dr Gavin Hudson
Professor Patrick Chinnery
Dr Patrick Yu Wai Man
et al.
Raised Intraocular Pressure as a Potential Risk Factor for Visual Loss in Leber Hereditary Optic Neuropathy2013
Dr Kamil Sitarz
Dr Angela Pyle
Professor Rita Horvath
Philip Griffiths
Professor Patrick Chinnery
et al.
Redefining Wolfram syndrome in the molecular Era2013
Dr Patrick Yu Wai Man
Philip Griffiths
Steroids for traumatic optic neuropathy2013
Philip Griffiths
Professor Patrick Chinnery
Dr Patrick Yu Wai Man
Visual and psychological morbidity among patients with autosomal dominant optic atrophy2013
Dr Patrick Yu Wai Man
Dr Sanatan Chattopadhyay
Philip Griffiths
Professor Patrick Chinnery
A randomized placebo-controlled trial of idebenone in Leber's hereditary optic neuropathy2011
Philip Griffiths
A Supranuclear Disorder of Ocular Motility as a Rare Initial Presentation of Motor Neurone Disease2011
Dr Patrick Yu Wai Man
Philip Griffiths
Professor Patrick Chinnery
Mitochondrial optic neuropathies - Disease mechanisms and therapeutic strategies2011
Dr Patrick Yu Wai Man
Professor Mike Trenell
Dr Kieren Hollingsworth
Philip Griffiths
Professor Patrick Chinnery
et al.
OPA1 mutations impair mitochondrial function in both pure and complicated dominant optic atrophy2011
Dr Patrick Yu Wai Man
Professor Patrick Chinnery
Philip Griffiths
Pattern of retinal ganglion cell loss in dominant optic atrophy due to OPA1 mutations2011
Dr Patrick Yu Wai Man
Philip Griffiths
Steroids for traumatic optic neuropathy2011
Dr Mark Baker
Dr Karen Fisher
Professor Roger Whittaker
Philip Griffiths
Dr Patrick Yu Wai Man
et al.
Subclinical multisystem neurologic disease in "pure" OPA1 autosomal dominant optic atrophy2011
Dr Gavin Hudson
Dr Patrick Yu Wai Man
Philip Griffiths
Professor Rita Horvath
Professor Patrick Chinnery
et al.
Variation in MAPT is not a contributing factor to the incomplete penetrance in LHON2011
Dr Patrick Yu Wai Man
Kamil Sitarz
Dr David Samuels
Philip Griffiths
Dr Amy Reeve
et al.
OPA1 mutations cause cytochrome c oxidase deficiency due to loss of wild-type mtDNA molecules2010
Philip Griffiths
Professor Patrick Chinnery
Eye movement recordings to investigate a supranuclear component in chronic progressive external ophthalmoplegia: a cross-sectional study2010
Dr Laura Greaves
Dr Patrick Yu Wai Man
Kim Krishnan
Nina Beadle
Dr Martin Barron
et al.
Mitochondrial DNA Defects and Selective Extraocular Muscle Involvement in CPEO2010
Dr Patrick Yu Wai Man
Philip Griffiths
Professor Grainne Gorman
Professor Roger Whittaker
Dr Mark Baker
et al.
Multi-system neurological disease is common in patients with OPA1 mutations2010
Dr Patrick Yu Wai Man
Joanna Stewart
Dr Gavin Hudson
Dr Richard Andrews
Philip Griffiths
et al.
OPA1 increases the risk of normal but not high tension glaucoma2010
Dr Patrick Yu Wai Man
Dr Gillian Borthwick
Dr Langping He
Geoffrey Taylor
Dr Laura Greaves
et al.
Somatic Mitochondrial DNA Deletions Accumulate to High Levels in Aging Human Extraocular Muscles2010
Dr Patrick Yu Wai Man
Philip Griffiths
Dr Ailbhe Burke
Michael Clarke
Dr Gavin Hudson
et al.
The Prevalence and Natural History of Dominant Optic Atrophy Due to OPA1 Mutations2010
Dr Gavin Hudson
Dr Patrick Yu Wai Man
Philip Griffiths
Professor Patrick Chinnery
Variation in OPA1 does not explain the incomplete penetrance of Leber hereditary optic neuropathy2010
Dr Patrick Yu Wai Man
Philip Griffiths
Dr Gavin Hudson
Professor Patrick Chinnery
Inherited mitochondrial optic neuropathies2009
Matthew Kirkman
Philip Griffiths
Dr Gavin Hudson
Professor Patrick Chinnery
Dr Patrick Yu Wai Man
et al.
Quality of Life in Patients with Leber Hereditary Optic Neuropathy2009
Joanna Stewart
Dr Gavin Hudson
Dr Patrick Yu Wai Man
Professor Rita Horvath
Philip Griffiths
et al.
OPA1 in multiple mitochondrial DNA deletion disorders2008
Professor Robert Taylor
Dr Laura Greaves
Dr Martin Barron
Philip Griffiths
Emeritus Professor Doug Turnbull
et al.
A histochemical and molecular genetic investigation of the selective, extraocular muscle involvement in chronic progressive external ophthalmoplegia2008
Dr Patrick Yu Wai Man
Philip Griffiths
Professor Patrick Chinnery
Investigation of auditory dysfunction in Leber hereditary optic neuropathy2008
Dr Patrick Yu Wai Man
Dr David Bateman
Dr Gavin Hudson
Philip Griffiths
Professor Patrick Chinnery
et al.
Leber hereditary optic neuropathy presenting in a 75-year-old man2008
Dr Gavin Hudson
Joanna Stewart
Emeritus Professor Mike Sir Michael Rawlins
Dr Andrew Schaefer
Philip Griffiths
et al.
Mutation of OPA1 causes dominant optic atrophy with external ophthalmoplegia, ataxia, deafness and multiple mitochondrial DNA deletions: A novel disorder of mtDNA maintenance2008
Nicholas Wride
Philip Griffiths
Nicholas Strong
Michael Clarke
Opaque intraocular lens for intractable diplopia: Experience and patients' expectations and satisfaction2008
Dr Gavin Hudson
Catherine Mowbray
Dr Angela Pyle
Dr Joanna Elson
Philip Griffiths
et al.
Clinical expression of Leber heriditary optic neuropathy is affected by the mitochondrial DNA-haplogroup background2007
Dr Evelyn Jaros
Dr Don Mahad
Dr Gavin Hudson
Dr Daniel Birchall
Philip Griffiths
et al.
Primary spinal cord neurodegeneration in Leber hereditary optic neuropathy2007
Dr Patrick Yu Wai Man
Philip Griffiths
Steroids for traumatic optic neuropathy2007
Professor Patrick Chinnery
Emeritus Professor Doug Turnbull
Philip Griffiths
Assessment of visual function in chronic progressive external ophthalmoplegia2006
Philip Griffiths
Dr Adam Zermansky
Professor David Burn
Characterising behavioural and cognitive dysexecutive changes in progressive supranuclear palsy: use of the Katz Adjustment Scale-Relatives (KAS-R)2006
Philip Griffiths
Dr Adam Zermansky
Professor David Burn
Characterizing behavioral and cognitive dysexecutive changes in progressive supranuclear palsy2006
Dr Richard Andrews
Emeritus Professor Doug Turnbull
Michael Birch
Sharon Foster
Professor Patrick Chinnery
et al.
The role of mitochondrial haplogroups in primary open angle glaucoma2006
Dr Ranjeet Pandit
Dr Michael Snow
Philip Griffiths
Unilateral recurrent acute retinal necrosis syndrome caused by cytomegalovirus in an immune-competent adult2006
Philip Griffiths
Sharon Foster
Professor Patrick Chinnery
Michael Birch
A polymorphism at codon 31 of gene p21 is not associated with primary open angle glaucoma in Caucasians2005
Professor Patrick Chinnery
Philip Griffiths
Extraocular muscles have fundamentally distinct properties that make them selectively vulnerable to certain disorders2005
Dr Gavin Hudson
Dr Patrick Yu Wai Man
Philip Griffiths
Professor Rita Horvath
Professor Patrick Chinnery
et al.
Identification of an X-chromosomal locus and haplotype modulating the phenotype of a mitochondrial DNA disorder2005
Dr Terence Smith
Dr Andrew Schaefer
Emeritus Professor Doug Turnbull
Philip Griffiths
Ocular motility findings in chronic progressive external ophthalmoplegia2005
Dr Andrew Schaefer
Philip Griffiths
Emeritus Professor Doug Turnbull
Professor Robert Taylor
Ophthalmoplegia due to mitochondrial DNA disease: The need for genetic diagnosis2005
Professor Patrick Chinnery
Philip Griffiths
Optic mitochondriopathies2005
Dr Cynthia Yu Wai Man
Professor Patrick Chinnery
Philip Griffiths
Optic neuropathies - Importance of spatial distribution of mitochondria as well as function2005
Dr Patrick Yu Wai Man
Philip Griffiths
Surgery for traumatic optic neuropathy2005
Dr Thomas Ressiniotis
Philip Griffiths
Dr Mark Birch
Sharon Foster
Professor Patrick Chinnery
et al.
Apolipoprotein E promoter polymorphisms do not have a major influence on the risk of developing primary open angle glaucoma2004
Philip Griffiths
Medically unexplained visual loss in adult patients2004
Dr Ranjeet Pandit
Philip Griffiths
Metastatic endogenous endophthalmitis secondary to Staphylococcus aureus iliopsoas abscess2004
Dr Martin Barron
Philip Griffiths
Emeritus Professor Doug Turnbull
Mitochondria and the eye: ageing and disease2004
Dr Andrew Schaefer
Dr Martin Barron
Philip Griffiths
Professor Robert Taylor
Emeritus Professor Doug Turnbull
et al.
Ophthalmoplegia: When all the tests are negative2004
Dr Sukhpal Sandhu
Philip Griffiths
Michael Birch
Optical coherence tomography scan acquisition protocol in assessing diabetic macular oedema in patients undergoing argon laser treatment2004
Dr Thomas Ressiniotis
Philip Griffiths
Dr Mark Birch
Sharon Foster
Professor Patrick Chinnery
et al.
Primary open angle glaucoma is associated with a specific p53 gene haplotype2004
Dr Martin Barron
Philip Griffiths
Emeritus Professor Doug Turnbull
Emeritus Professor David Bates
Dr Philip Nichols
et al.
The distributions of mitochondria and sodium channels reflect the specific energy requirements and conduction properties of the human optic nerve head2004
Dr Thomas Ressiniotis
Philip Griffiths
Dr Mark Birch
Sharon Foster
Professor Patrick Chinnery
et al.
The Role of Apolipoprotein E Gene Polymorphisms in Primary Open-angle Glaucoma2004
Dr Thomas Ressiniotis
Philip Griffiths
Michael Birch
Professor Patrick Chinnery
Apolipoprotein E gene polymorphisms in Primary Open Angle Glaucoma2003
Philip Griffiths
Dying for drugs - Drug companies should not have to subsidise incompetent governments2003
Zoe Johnson
Philip Griffiths
Michael Birch
Nurse prescribing in glaucoma2003
Philip Griffiths
Dr Andrew Schaefer
Emeritus Professor Doug Turnbull
Ocular motility findings in chronic progressive external ophthalmoplegia2003
Dr Patrick Yu Wai Man
Philip Griffiths
Emeritus Professor Doug Turnbull
Professor Patrick Chinnery
The epidemiology of Leber hereditary optic neuropathy in the North East of England2003
Philip Griffiths
Dr Richard Andrews
Emeritus Professor Doug Turnbull
The distribution of mitochondrial activity in relation to optic nerve structure2002
Philip Griffiths
Dr Martin Barron
Dr Steve Durham
Michael Clarke
Emeritus Professor Doug Turnbull
et al.
Distribution of mitochondrial dysfunction in ageing ocular tissues.2001
Dr Ranjeet Pandit
Philip Griffiths
Effectiveness of testing visual fields by confrontation2001
Dr Martin Barron
Dr Margaret Johnson
Dr Richard Andrews
Michael Clarke
Philip Griffiths
et al.
Mitochondrial abnormalities in ageing macular photoreceptors2001
Philip Griffiths
Automated perimetry by optometrists in patients at low risk of glaucoma [Reply]1999
Dr Richard Andrews
Philip Griffiths
Professor Patrick Chinnery
Emeritus Professor Doug Turnbull
Evaluation of bupivacaine-induced muscle regeneration in the treatment of ptosis in patients with chronic progressive external ophthalmoplegia and Kearns-Sayre syndrome1999
Dr Richard Andrews
Philip Griffiths
Dr Margaret Johnson
Emeritus Professor Doug Turnbull
Histochemical localisation of mitochondrial enzyme activity in human optic nerve and retina1999
Dr Richard Andrews
Philip Griffiths
Professor Patrick Chinnery
Emeritus Professor Doug Turnbull
Mitochondrial DNA disease masquerading as age-related macular degeneration1999
Philip Griffiths
Untitled1999