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Discovery of ASTX295, a potent, next-generation small molecule antagonist of MDM2 with differentiated pharmacokinetic profile

Lookup NU author(s): Dr Celine CanoORCiD, Professor Jane Endicott, Dr Ian HardcastleORCiD, Dr Claire Jennings, Suzanne Kyle, Professor John LunecORCiD, Duncan Miller, Professor Martin NobleORCiD, Huw ThomasORCiD, Professor Steve Wedge, Dr Elaine WillmoreORCiD, Dr Yan Zhao


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Publication metadata

Author(s): Ahn M, Bevan L, Buck I, Cano C, Castro J, Cons B, Endicott J, Fazal L, Ferrari N, Hardcastle I, Hearn K, Holvey R, Howard S, Johnson C, Jennings C, Kucia-Tran J, Kyle S, Lunec J, Lyons J, Miller D, Rees D, Noble M, Newell DR, Reeks J, Saini H, St Denis J, Tamanini E, Thomas H, Thompson N, Vinkovic M, Ward G, Wallis N, Walton H, Wedge S, Williams P, Willmore E, Wilshire N, Zhao Y, Chessari G

Publication type: Conference Proceedings (inc. Abstract)

Publication status: Published

Conference Name: American Association for Cancer Research Annual Meeting

Year of Conference: 2024

Pages: 6588

Print publication date: 22/03/2024

Online publication date: 22/03/2024

Acceptance date: 22/03/2024

Publisher: AACR Journals


DOI: 10.1158/1538-7445.AM2024-6588

Notes: Online ISSN: 1538-7445 Print ISSN: 0008-5472

Library holdings: Search Newcastle University Library for this item

Series Title: Cancer Research

ISBN: 15387445