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Browsing publications by
Dr Claire Jennings.
Newcastle Authors
Title
Year
Full text
Dr Celine Cano
Professor Jane Endicott
Dr Ian Hardcastle
Dr Claire Jennings
Suzanne Kyle
et al.
Discovery of ASTX295, a potent, next-generation small molecule antagonist of MDM2 with differentiated pharmacokinetic profile
2024
Islam Al-Khawaldeh
Dr Christine Basmadjian
Dr Cinzia Bordoni
Dr Suzannah Harnor
Amy Heptinstall
et al.
An alkynylpyrimidine-based covalent inhibitor that targets a unique cysteine in NF-κB-inducing kinase (NIK)
2021
Melanie Griffin
Dr Claire Jennings
Professor Gareth Veal
Dactinomycin induces complete remission associated with nucleolar stress response in relapsed/refractory
NPM1
-mutated acute myeloid leukemia
2021
Dr Ian Hardcastle
Dr Ruth Bawn
Dr Tim Blackburn
Dr Celine Cano
Dr Sarah Cully
et al.
Structure-Based Design of Potent and Orally Active Isoindolinone Inhibitors of MDM2-p53 Protein–Protein Interaction
2021
Zoe Rutter
Dr Claire Jennings
Dr Richard Lewis
Dr Sven Halbedel
PrkA controls peptidoglycan biosynthesis through the essential phosphorylation of ReoM
2020
Dr Claire Jennings
Dr Judith Reeks
Jieman Meng
Professor Martin Noble
Tuning the binding affinity and selectivity of perfluoroaryl-stapled peptides by cysteine-editing
2019
Duncan Miller
Dr Mathew Martin
Santosh Adhikari
Alfie Brennan
Professor Jane Endicott
et al.
Identification of a novel ligand for the ATAD2 bromodomain with selectivity over BRD4 through a fragment growing approach
2018
Dr Judith Reeks
Dr Claire Jennings
Professor Martin Noble
Benzene Probes in Molecular Dynamics Simulations Reveal Novel Binding Sites for Ligand Design
2016