Rob Atkinson Dr Maria Georgiou Dr Chunbo Yang Marina Moya Molina Dr Joseph Collin et al. | PRPF8-mediated dysregulation of hBrr2 helicase disrupts human spliceosome kinetics and 5´-splice-site selection causing tissue-specific defects | 2024 |
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Dr Marzena Kurzawa-Akanbi Dr Florence Burte Dr Birthe Hilgen Dr Rachel Queen Dr Jonathan Coxhead et al. | Retinal pigment epithelium extracellular vesicles are potent inducers of age-related macular degeneration disease phenotype in the outer retina | 2022 |
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Dr Joseph Collin Dr Rachel Queen Dr Darin Zerti Professor David Steel Professor Majlinda Lako et al. | Dissecting the transcriptional and chromatin accessibility heterogeneity of proliferating cone precursors in human retinoblastoma tumours by single cell sequencing- opening pathways to new therapeutic strategies? | 2021 |
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Professor Lyle Armstrong Dr Joseph Collin Dr Islam Mostafa Dr Rachel Queen Professor Francisco Figueiredo et al. | In the eye of the storm: SARS-CoV-2 infection and replication at the ocular surface? | 2021 |
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Dr Chunbo Yang Dr Maria Georgiou Rob Atkinson Dr Joseph Collin Professor Lyle Armstrong et al. | Pre-mRNA Processing Factors and Retinitis Pigmentosa: RNA Splicing and Beyond | 2021 |
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Dr Darin Zerti Dr Birthe Hilgen Dr Joseph Collin Professor Lyle Armstrong Professor Evelyne Sernagor et al. | Transplanted pluripotent stem cell‐derived photoreceptor precursors elicit conventional and unusual light responses in mice with advanced retinal degeneration | 2021 |
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Dr Joseph Collin Dr Rachel Queen Dr Darin Zerti Dr Birthe Hilgen Maria Georgiou et al. | Co-expression of SARS-CoV-2 entry genes in the superficial adult human conjunctival, limbal and corneal epithelium suggests an additional route of entry via the ocular surface | 2020 |
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Dr Carla Jackson Dr Roman Bauer Dr Joseph Collin Dr Birthe Hilgen Dr Darin Zerti et al. | An integrated transcriptional analysis of the developing human retina | 2019 |
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Dr Joseph Collin Dr Darin Zerti Dr Rachel Queen Dr Roman Bauer Dr Jonathan Coxhead et al. | CRX Expression in Pluripotent Stem Cell‐Derived Photoreceptors Marks a Transplantable Subpopulation of Early Cones | 2019 |
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Dr Joseph Collin Dr Rachel Queen Dr Darin Zerti Dr Birthe Hilgen Raf Hussain et al. | Deconstructing Retinal Organoids: Single cell RNA-Seq reveals the cellular components of human pluripotent stem cell-derived retina | 2019 |
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Dr Carla Jackson Dr Joseph Collin Dr Rachel Queen Dr Birthe Hilgen Dr Darin Zerti et al. | Systematic Comparison of Retinal Organoid Differentiation from Human Pluripotent Stem Cells Reveals Stage Specific, Cell Line, and Methodological Differences | 2019 |
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Dr Osagie Izuogu Dr Carla Mellough Dr Joseph Collin Dr Richard Gallon Francesco Kumara Mastrorosa et al. | Analysis of human ES cell differentiation establishes that the dominant isoforms of the lncRNAs RMST and FIRRE are circular | 2018 |
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Dr Valeria Chichagova Dr Dean Hallam Dr Joseph Collin Dr Darin Zerti Dr Birthe Hilgen et al. | Cellular regeneration strategies for macular degeneration: past, present and future | 2018 |
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Dr Sanja Bojic Dr Joseph Collin Dr Min Yu Professor Lyle Armstrong Professor Francisco Figueiredo et al. | Differences in the activity of endogenous BMP signalling impact on the ability of induced pluripotent stem cells to differentiate to corneal epithelial like cells | 2018 |
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Majed Felemban Dr Birthe Hilgen Dr Nicola Hunt Dr Dean Hallam Dr Darin Zerti et al. | Extracellular matrix components expression in human pluripotent stem cell-derived retinal organoids recapitulates retinogenesis in vivo and reveals an important role for IMPG1 and CD44 in the development of photoreceptors and interphotoreceptor matrix | 2018 |
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Dr Dean Hallam Dr Joseph Collin Dr Sanja Bojic Dr Valeria Chichagova Dr Adriana Buskin et al. | An iPSC patient specific model of CFH (Y402H) polymorphism displays characteristic features of AMD and indicates a beneficial role for UV light exposure | 2017 |
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Dr Valeria Chichagova Dr Dean Hallam Dr Joseph Collin Dr Adriana Buskin Dr Gabriele Saretzki et al. | Human iPSC disease modelling reveals functional and structural defects in retinal pigment epithelial cells harbouring the m.3243A>G mitochondrial DNA mutation | 2017 |
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Dr Joseph Collin Dr Lili Zhu Professor Lyle Armstrong Dr Irina Neganova Professor Majlinda Lako et al. | A Novel role for miR-1305 in Regulation of Pluripotency-Differentiation Balance, Cell Cycle and Apoptosis in Human Pluripotent Stem Cells | 2016 |
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Dr Tomas Barta Dr Joseph Collin Dr Irina Neganova Professor Lyle Armstrong Professor Majlinda Lako et al. | Inhibition of miR-145 Enhances Reprogramming of Human Dermal Fibroblasts to Induced Pluripotent Stem Cells | 2016 |
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Dr Joseph Collin Dr Carla Jackson Dr Birthe Hilgen Professor Majlinda Lako
| Using Zinc Finger Nuclease Technology to Generate CRX-Reporter Human Embryonic Stem Cells as a Tool to Identify and Study the Emergence of Photoreceptors Precursors During Pluripotent Stem Cell Differentiation | 2016 |
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Dr Joseph Collin
| A novel zinc finger gene, ZNF465, is inappropriately expressed in acute myeloid leukaemia cells | 2015 |
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Professor Majlinda Lako Dr Joseph Collin Dr Carla Jackson Dr Birthe Hilgen
| Using zinc finger nuclease technology to generate reporter-labelled human pluripotent stem cells as a tool to optimize photoreceptor transplantation | 2015 |
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Dr Saba Habibollah Dr Katarzyna Tilgner Dr Joseph Collin Dr Tomas Barta Raf Hussain et al. | An Induced Pluripotent Stem Cell Model of Hypoplastic Left Heart Syndrome (HLHS) Reveals Multiple Expression and Functional Differences in HLHS-Derived Cardiac Myocytes | 2014 |
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Dr Carla Jackson Dr Joseph Collin Professor Evelyne Sernagor Nicholas Wride Professor David Steel et al. | Lab generated retina: Realizing the dream | 2014 |
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Stuart Atkinson Dr Joseph Collin Dr George Anyfantis Professor Majlinda Lako Professor Lyle Armstrong et al. | A Putative Role for the Immunoproteasome in the Maintenance of Pluripotency in Human Embryonic Stem Cells | 2012 |
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Dr Joseph Collin Professor Majlinda Lako
| Concise Review: Putting a Finger on Stem Cell Biology: Zinc Finger Nuclease-Driven Targeted Genetic Editing in Human Pluripotent Stem Cells | 2011 |
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