Dr Maria Georgiou Alex Chaudhary Dr Joseph Collin Dr Rachel Queen Dr Birthe Hilgen et al. | Human Retinal Organoids Provide a Suitable Tool for Toxicological Investigations: A Comprehensive Validation Using Drugs and Compounds Affecting the Retina | 2022 |
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Dr Marzena Kurzawa-Akanbi Dr Florence Burte Dr Birthe Hilgen Dr Rachel Queen Dr Jonathan Coxhead et al. | Retinal pigment epithelium extracellular vesicles are potent inducers of age-related macular degeneration disease phenotype in the outer retina | 2022 |
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Dr Darin Zerti Marina Moya-Molina Dr Birthe Hilgen Dr Roman Bauer Professor Majlinda Lako et al. | IGFBPs mediate IGF-1’s functions in retinal lamination and photoreceptor development during pluripotent stem cell differentiation to retinal organoids | 2021 |
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Dr Darin Zerti Dr Birthe Hilgen Dr Joseph Collin Professor Lyle Armstrong Professor Evelyne Sernagor et al. | Transplanted pluripotent stem cell‐derived photoreceptor precursors elicit conventional and unusual light responses in mice with advanced retinal degeneration | 2021 |
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Dr Joseph Collin Dr Rachel Queen Dr Darin Zerti Dr Birthe Hilgen Maria Georgiou et al. | Co-expression of SARS-CoV-2 entry genes in the superficial adult human conjunctival, limbal and corneal epithelium suggests an additional route of entry via the ocular surface | 2020 |
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Dr Darin Zerti Dr Birthe Hilgen Majed Felemban Dr Ali Ghareeb Dr Min Yu et al. | Developing a simple method to enhance the generation of cone and rod photoreceptors in pluripotent stem cell‐derived retinal organoids | 2020 |
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Dr Maria Georgiou Dr Valeria Chichagova Dr Birthe Hilgen Professor Evelyne Sernagor Professor Lyle Armstrong et al. | Room temperature shipment does not affect the biological activity of pluripotent stem cell-derived retinal organoids | 2020 |
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Dr Carla Jackson Dr Roman Bauer Dr Joseph Collin Dr Birthe Hilgen Dr Darin Zerti et al. | An integrated transcriptional analysis of the developing human retina | 2019 |
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Majed Felemban Dr Birthe Hilgen Dr Darin Zerti Dr Nicola Hunt Dr Dean Hallam et al. | Decellularised extracellular matrix-derived peptides from neural retina and retinal pigment epithelium enhance the expression of synaptic markers and light responsiveness of human pluripotent stem cell derived retinal organoids | 2019 |
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Dr Joseph Collin Dr Rachel Queen Dr Darin Zerti Dr Birthe Hilgen Raf Hussain et al. | Deconstructing Retinal Organoids: Single cell RNA-Seq reveals the cellular components of human pluripotent stem cell-derived retina | 2019 |
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Dr Valeria Chichagova Dr Birthe Hilgen Majed Felemban Dr Maria Georgiou Professor Lyle Armstrong et al. | Differentiation of Retinal Organoids from Human Pluripotent Stem Cells | 2019 |
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Dr Carla Jackson Dr Joseph Collin Dr Rachel Queen Dr Birthe Hilgen Dr Darin Zerti et al. | Systematic Comparison of Retinal Organoid Differentiation from Human Pluripotent Stem Cells Reveals Stage Specific, Cell Line, and Methodological Differences | 2019 |
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Dr Valeria Chichagova Dr Dean Hallam Dr Joseph Collin Dr Darin Zerti Dr Birthe Hilgen et al. | Cellular regeneration strategies for macular degeneration: past, present and future | 2018 |
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Majed Felemban Dr Birthe Hilgen Dr Nicola Hunt Dr Dean Hallam Dr Darin Zerti et al. | Extracellular matrix components expression in human pluripotent stem cell-derived retinal organoids recapitulates retinogenesis in vivo and reveals an important role for IMPG1 and CD44 in the development of photoreceptors and interphotoreceptor matrix | 2018 |
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Dr Dean Hallam Dr Birthe Hilgen Dr Lili Zhu Dr Min Yu Dr Sanja Bojic et al. | Human induced pluripotent stem cells generate light responsive retinal organoids with variable and nutrient dependent efficiency | 2018 |
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Dr Birthe Hilgen Majed Felemban Alex Sharpe Dr Roman Bauer Dr Dean Hallam et al. | Laminin γ3 plays an important role in retinal lamination, photoreceptor organisation and ganglion cell differentiation | 2018 |
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Dr Joseph Collin Dr Carla Jackson Dr Birthe Hilgen Professor Majlinda Lako
| Using Zinc Finger Nuclease Technology to Generate CRX-Reporter Human Embryonic Stem Cells as a Tool to Identify and Study the Emergence of Photoreceptors Precursors During Pluripotent Stem Cell Differentiation | 2016 |
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Dr Birthe Hilgen
| Connexin50 couples axon terminals of mouse horizontal cells by homotypic gap junctions | 2015 |
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Majed Felemban Dr Nicola Hunt Dr Birthe Hilgen Dr Carla Mellough Professor Majlinda Lako et al. | Investigation of extracellular matrix (ECM) component expression in developing retina | 2015 |
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Professor Majlinda Lako Dr Joseph Collin Dr Carla Jackson Dr Birthe Hilgen
| Using zinc finger nuclease technology to generate reporter-labelled human pluripotent stem cells as a tool to optimize photoreceptor transplantation | 2015 |
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Dr Gerrit Hilgen Dr Birthe Hilgen
| AII amacrine cells discriminate between heterocellular and homocellular locations when assembling connexin36-containing gap junctions | 2014 |
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Dr Katarina Kranz Dr Birthe Hilgen
| Expression of Pannexin1 in the outer plexiform layer of the mouse retina and physiological impact of its knockout | 2013 |
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Dr Birthe Hilgen
| Ablation of Retinal Horizontal Cells from Adult Mice Leads to Rod Degeneration and Remodeling in the Outer Retina | 2012 |
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