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Browsing publications by Dr Birthe Hilgen

Newcastle AuthorsTitleYearFull text
Dr Maria Georgiou
Alex Chaudhary
Dr Joseph Collin
Dr Rachel Queen
Dr Birthe Hilgen
et al.		Human Retinal Organoids Provide a Suitable Tool for Toxicological Investigations: A Comprehensive Validation Using Drugs and Compounds Affecting the Retina2022
Dr Marzena Kurzawa-Akanbi
Florence Burté
Dr Birthe Hilgen
Dr Rachel Queen
Dr Jonathan Coxhead
et al.		Retinal pigment epithelium extracellular vesicles are potent inducers of age-related macular degeneration disease phenotype in the outer retina2022
Dr Darin Zerti
Marina Moya-Molina
Dr Birthe Hilgen
Dr Roman Bauer
Professor Majlinda Lako
IGFBPs mediate IGF-1’s functions in retinal lamination and photoreceptor development during pluripotent stem cell differentiation to retinal organoids2021
Dr Darin Zerti
Dr Birthe Hilgen
Dr Joseph Collin
Professor Lyle Armstrong
Professor Evelyne Sernagor
et al.		Transplanted pluripotent stem cell‐derived photoreceptor precursors elicit conventional and unusual light responses in mice with advanced retinal degeneration2021
Dr Joseph Collin
Dr Rachel Queen
Dr Darin Zerti
Dr Birthe Hilgen
Maria Georgiou
et al.		Co-expression of SARS-CoV-2 entry genes in the superficial adult human conjunctival, limbal and corneal epithelium suggests an additional route of entry via the ocular surface2020
Dr Darin Zerti
Dr Birthe Hilgen
Majed Felemban
Dr Ali Ghareeb
Dr Min Yu
et al.		Developing a simple method to enhance the generation of cone and rod photoreceptors in pluripotent stem cell‐derived retinal organoids 2020
Dr Maria Georgiou
Dr Valeria Chichagova
Dr Birthe Hilgen
Professor Evelyne Sernagor
Professor Lyle Armstrong
et al.		Room temperature shipment does not affect the biological activity of pluripotent stem cell-derived retinal organoids2020
Dr Carla Jackson
Dr Roman Bauer
Dr Joseph Collin
Dr Birthe Hilgen
Dr Darin Zerti
et al.		An integrated transcriptional analysis of the developing human retina2019
Majed Felemban
Dr Birthe Hilgen
Dr Darin Zerti
Dr Nicola Hunt
Dr Dean Hallam
et al.		Decellularised extracellular matrix-derived peptides from neural retina and retinal pigment epithelium enhance the expression of synaptic markers and light responsiveness of human pluripotent stem cell derived retinal organoids2019
Dr Joseph Collin
Dr Rachel Queen
Dr Darin Zerti
Dr Birthe Hilgen
Raf Hussain
et al.		Deconstructing Retinal Organoids: Single cell RNA-Seq reveals the cellular components of human pluripotent stem cell-derived retina2019
Dr Valeria Chichagova
Dr Birthe Hilgen
Majed Felemban
Dr Maria Georgiou
Professor Lyle Armstrong
et al.		Differentiation of Retinal Organoids from Human Pluripotent Stem Cells2019
Dr Carla Jackson
Dr Joseph Collin
Dr Rachel Queen
Dr Birthe Hilgen
Dr Darin Zerti
et al.		Systematic Comparison of Retinal Organoid Differentiation from Human Pluripotent Stem Cells Reveals Stage Specific, Cell Line, and Methodological Differences2019
Dr Valeria Chichagova
Dr Dean Hallam
Dr Joseph Collin
Dr Darin Zerti
Dr Birthe Hilgen
et al.		Cellular regeneration strategies for macular degeneration: past, present and future2018
Majed Felemban
Dr Birthe Hilgen
Dr Nicola Hunt
Dr Dean Hallam
Dr Darin Zerti
et al.		Extracellular matrix components expression in human pluripotent stem cell-derived retinal organoids recapitulates retinogenesis in vivo and reveals an important role for IMPG1 and CD44 in the development of photoreceptors and interphotoreceptor matrix2018
Dr Dean Hallam
Dr Birthe Hilgen
Dr Lili Zhu
Dr Min Yu
Dr Sanja Bojic
et al.		Human induced pluripotent stem cells generate light responsive retinal organoids with variable and nutrient dependent efficiency2018
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