Dr Sarah Rice Dr Jack Roberts Maria Tselepi Abby Brumwell Professor John Loughlin et al. | Genetic and Epigenetic Fine-Tuning of TGFB1 Expression Within the Human Osteoarthritic Joint | 2021 |
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Dr Tony Sorial Ines Hofer Maria Tselepi Kat Cheung Dr Eleanor Parker et al. | Multi-tissue epigenetic analysis of the osteoarthritis susceptibility locus mapping to the plectin gene PLEC | 2020 |
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Dr Sarah Rice Maria Tselepi Dr Tony Sorial Guillaume Aubourg Dr Colin Shepherd et al. | Prioritization of PLEC and GRINA as osteoarthritis risk genes through the identification and characterization of novel methylation quantitative trait loci | 2019 |
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Dr Madhushika Ratnayake Maria Tselepi Professor John Loughlin
| Genome-wide association study of developmental dysplasia of the hip identifies an association with GDF5 | 2018 |
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Dr Sarah Rice Guillaume Aubourg Dr Tony Sorial Dr David Almarza Gomez Maria Tselepi et al. | Identification of a novel, methylation-dependent, RUNX2 regulatory region associated with osteoarthritis risk | 2018 |
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Dr Sarah Rice Dr Tony Sorial Guillaume Aubourg Dr Colin Shepherd Maria Tselepi et al. | Identification of novel methylation quantitative trait loci (mqtls) and functional characterization using CRISPR/CAS9 and gene expression analysis prioritizes PLEC as an OA risk gene | 2018 |
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Dr Madhushika Ratnayake Maria Tselepi Dr Louise Reynard Professor John Loughlin
| A consistent and potentially exploitable response during chondrogenesis of mesenchymal stem cells from osteoarthritis patients to the protein encoded by the susceptibility gene GDF5 | 2017 |
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Maria Tselepi Madhushika Ratnayake Dr Louise Reynard Professor John Loughlin
| Differences in the response of mesenchymal stem cells from healthy donors and OA patients to exogenous GDF5 during chondrogenic differentiation | 2016 |
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Dr Matthew Barter Maria Tselepi Dr Rodolfo Gomez Steven Woods Dr Graham Smith et al. | Genome-wide microRNA and gene analysis of mesenchymal stem cell chondrogenesis identifies an essential role and multiple targets for miR-140-5p | 2015 |
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