Caroline Dalgliesh Saad Aldalaqan Christian Atallah Dr Andrew Best Dr Emma Scott et al. | An ultra-conserved poison exon in the Tra2b gene encoding a splicing activator is essential for male fertility and meiotic cell division | 2025 |
|
Chile Siachisumo Dr Sara Luzzi Saad Aldalaqan Dr Gerald Hysenaj Caroline Dalgliesh et al. | An anciently diverged family of RNA binding proteins maintain correct splicing of a class of ultra-long exons through cryptic splice site repression | 2024 |
|
Marina Moya-Molina Emily Flood Dr Jonathan Coxhead Dr Graham Smith Professor Lyle Armstrong et al. | Deciphering the impact of PROM1 alternative splicing on human photoreceptor development and maturation | 2024 |
|
Dr Cahyo Wibowo Mohammed Alshaharni Dr Graham Smith Professor Angharad MR Gatehouse Dr Martin Edwards et al. | Molecular basis of resistance to leaf spot disease in oil palm | 2024 |
|
Lucy Gee Dr Ben Barron-Millar Dr Marco Zaki Dr Saimir Luli Rachel Burgoyne et al. | Anti–Cholestatic Therapy with Obeticholic Acid Improves Short-Term Memory in Bile Duct–Ligated Mice | 2023 |
|
Dr Beth Adamson Nicholas Brittain Dr Laura Walker Ruaridh Duncan Dr Sara Luzzi et al. | The catalytic subunit of DNA-PK regulates transcription and splicing of AR in advanced prostate cancer | 2023 |
|
Dr Fedor Shmarov Dr Graham Smith Dr Sophie Weatherhead Professor Nick Reynolds Dr Paolo Zuliani et al. | Individualised computational modelling of immune mediated disease onset, flare and clearance in psoriasis | 2022 |
|
Dr Faye Cooles Jessica Tarn Dr Dennis Lendrem Najib Naamane Alice Lin et al. | Interferon-α-mediated therapeutic resistance in early rheumatoid arthritis implicates epigenetic reprogramming | 2022 |
|
Dr Tetsushi Kataura Gisela Otten Dr Yoana Rabanal Ruiz Francesca Urselli Dr Filippo Scialo et al. | NDP52 acts as a redox sensor in PINK1/Parkin-mediated mitophagy | 2022 |
|
Professor John Isaacs Sarah Brockbank Dr Ayako Pedersen Professor Catharien Hilkens Dr Amy Anderson et al. | RA-MAP, molecular immunological landscapes in early rheumatoid arthritis and healthy vaccine recipients | 2022 |
|
Professor David Jones Dr Aaron Wetten Dr Ben Barron-Millar Dr Laura Ogle Dr George Mells et al. | The relationship between disease activity and UDCA response criteria in primary biliary cholangitis: A cohort study | 2022 |
|
Dr Ben Barron-Millar Dr Laura Ogle Emeritus Professor John Kirby Dr Jeremy Palmer Dr Laura Jopson et al. | The Serum Proteome and Ursodeoxycholic Acid Response in Primary Biliary Cholangitis | 2021 |
|
Rachel Roberts Dr Sophie Weatherhead Dika Pawitri Dr Graham Smith Dr Ashley Rider et al. | Therapeutic wavelengths of ultraviolet B radiation activate apoptotic, circadian rhythm, redox signalling and key canonical pathways in psoriatic epidermis | 2021 |
|
Dr Julie Worrell Dr Jack Leslie Dr Graham Smith Marco Zaki Dr Hannah Paish et al. | cRel expression regulates distinct transcriptional and functional profiles driving fibroblast matrix production in systemic sclerosis | 2020 |
|
Dr Amy Anderson Dr Nicola Maney Dr Dennis Lendrem Julie Diboll Dr Philip Brown et al. | Expression of STAT3-regulated genes in circulating CD4+ T cells discriminates rheumatoid arthritis independently of clinical parameters in early arthritis | 2019 |
|
Dr Hannah Paish Dr Nicholas Kalson Dr Graham Smith Alicia Del Carpio Pons Nicholas Smith et al. | Fibroblasts Promote Inflammation and Pain via IL-1α Induction of the Monocyte Chemoattractant Chemokine (C-C Motif) Ligand 2 | 2018 |
|
Dr Bernadette Carroll Diego Manni Dr Rhoda Stefanatos Fiona Menzies Dr Graham Smith et al. | Oxidation of SQSTM1/p62 mediates the link between redox state and protein homeostasis | 2018 |
|
Dr Carole Proctor Dr Graham Smith
| Computer simulation models as a tool to investigate the role of microRNAs in osteoarthritis | 2017 |
|
Dr Bernadette Carroll Gisela Otten Matthew Ratcliff Dr Graham Smith Dr Joao Passos et al. | Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity | 2016 |
|
Lewis Tomalin Dr Alison Day Zoe Underwood Dr Graham Smith Dr Piero Dalle Pezze et al. | Increasing extracellular H2O2 produces a bi-phasic response in intracellular H2O2with peroxiredoxin hyperoxidation only triggered once the cellular H2O2-buffering capacity is overwhelmed | 2016 |
|
Dr Matthew Barter Maria Tselepi Dr Rodolfo Gomez Steven Woods Dr Graham Smith et al. | Genome-wide microRNA and gene analysis of mesenchymal stem cell chondrogenesis identifies an essential role and multiple targets for miR-140-5p | 2015 |
|
Dr Eva Moran Salvador Dr Pier Paoli Dr Graham Smith Dr Agata Page Rachel Howarth et al. | MeCP2 exerts global control over the myofibroblast transcriptome and reveals new regulators of fibrosis | 2015 |
|
Dr Caroline Wilson Dr Diana Jurk Nicola Fullard Paul Banks Dr Agata Page et al. | NFkB1 is a suppressor of neutrophil-driven hepatocellular carcinoma | 2015 |
|
Dr Graham Smith Dr Daryl Shanley
| Computational modelling of the regulation of Insulin signalling by oxidative stress | 2013 |
|
David Dolan Dr Glyn Nelson Dr Anze Zupanic Dr Graham Smith Dr Daryl Shanley et al. | Systems Modelling of NHEJ Reveals the Importance of Redox Regulation of Ku70/80 in the Dynamics of DNA Damage Foci | 2013 |
|
Dr Graham Smith Dr Daryl Shanley
| Modelling the Response of FOXO Transcription Factors to Multiple Post-Translational Modifications Made by Ageing-Related Signalling Pathways | 2010 |
|
Dr Graham Smith
| Molecular Dynamics Characterization of Protein Crystal Contacts in Aqueous Solutions | 2008 |
|
Dr Sandeep Pal Dr Graham Smith
| Protein-protein docking: Progress in CAPRI rounds 6-12 using a combination of methods: The introduction of steered solvated molecular dynamics | 2007 |
|
Dr Graham Smith
| Incorporation of flexibility into rigid-body docking: Applications in rounds 3-5 of CAPRI | 2005 |
|
Dr Graham Smith
| The relationship between the flexibility of proteins and their conformational states on forming protein-protein complexes with an application to protein-protein docking | 2005 |
|