Publications by Dr Colin Shepherd - ePrints

Browsing publications by Dr Colin Shepherd.

Newcastle Authors	Title	Year
Dr Sarah Rice Abby Brumwell Julia Falk Yulia Kehayova John Casement et al.	Genetic risk of osteoarthritis operates during human skeletogenesis	2023
Dr Wei-Yu Lin Dr Sarah Fordham Dr Nicola Sunter Dr Claire Elstob Dr Thahira Rahman et al.	Genome-wide association study identifies risk loci for progressive chronic lymphocytic leukemia	2021
Dr Colin Shepherd Abi Reese Dr Louise Reynard Professor John Loughlin	Expression analysis of the osteoarthritis genetic susceptibility mapping to the matrix Gla protein gene MGP	2019
Dr Sarah Rice Dr Colin Shepherd Professor John Loughlin	Functional testing of thousands of osteoarthritis-associated variants for regulatory activity	2019
Dr Sarah Rice Maria Tselepi Dr Tony Sorial Guillaume Aubourg Dr Colin Shepherd et al.	Prioritization of PLEC and GRINA as osteoarthritis risk genes through the identification and characterization of novel methylation quantitative trait loci	2019
Dr Colin Shepherd Dr Dongxing Zhu Andrew Skelton Dr Louise Reynard Professor John Loughlin et al.	Functional characterization of the osteoarthritis genetic risk residing at ALDH1A2 identifies rs12915901 as a key target variant.	2018
Dr Colin Shepherd Dr Louise Reynard Professor John Loughlin	Genotype at the MGP OA risk locus correlates with an expression quantitative trait locus operating on MGP in cartilage and with DNA methylation at a cluster of regulatory CpGs within ARHGDIB	2018
Dr Sarah Rice Dr Tony Sorial Guillaume Aubourg Dr Colin Shepherd Maria Tselepi et al.	Identification of novel methylation quantitative trait loci (mqtls) and functional characterization using CRISPR/CAS9 and gene expression analysis prioritizes PLEC as an OA risk gene	2018
Dr Colin Shepherd Dr Dongxing Zhu Andrew Skelton Dr Louise Reynard Professor John Loughlin et al.	Functional characterisation of the osteoarthritis genetic risk locus that resides at the gene ALDH1A2, coding for the retinoic acid synthesis enzyme RALDH2, identifies rs4646636 and rs12915901 as key target SNPs	2017
Dr Colin Shepherd Andrew Skelton Dr Michael Rushton Dr Louise Reynard Professor John Loughlin et al.	Expression analysis of the osteoarthritis genetic susceptibility locus mapping to an intron of the MCF2L gene and marked by the polymorphism rs11842874	2016
Dr Colin Shepherd Andrew Skelton Dr Michael Rushton Dr Louise Reynard Professor John Loughlin et al.	Expression analysis of the osteoarthritis genetic susceptibility locus mapping to an intron of the MCF2L gene and marked by the polymorphism rs11842874	2015
Dr Colin Shepherd	Improved Catenated Structures of Bovine Peroxiredoxin III F190L Reveal Details of Ring-Ring Interactions and a Novel Conformational State	2015
Dr Michael Rushton Dr Louise Reynard Professor David Young Dr Colin Shepherd Dr Rebecca Darlay et al.	Methylation of cartilage DNA is a mediator of genetic risk at several OA susceptibility loci	2015
Dr Michael Rushton Dr Louise Reynard Professor David Young Dr Colin Shepherd Dr Fiona Gee et al.	Methylation quantitative trait locus (meQTL) analysis of osteoarthritis links epigenetics with genetic risk	2015
Dr Colin Shepherd	Inactivation of mammalian Ero1α is catalysed by specific protein disulfide-isomerases	2014