Dr Brian Ford
Dr Shruti Chachra
Ahmed Alshawi
Professor Fiona Oakley
Professor Dina Tiniakos
et al. | Compromised chronic efficacy of a glucokinase activator AZD1656 in mouse models for common human GCKR variants | 2024 |
|
Dr Brian Ford
Dr Shruti Chachra
Ahmed Alshawi
Alfie Brennan
Dr Suzannah Harnor
et al. | Chronic glucokinase activator treatment activates liver Carbohydrate response element binding protein and improves hepatocyte ATP homeostasis during substrate challenge | 2020 |
|
Tabassum Moonira
Dr Shruti Chachra
Dr Brian Ford
Ahmed Alshawi
Dr Catherine Arden
et al. | Metformin lowers glucose 6-phosphate in hepatocytes by activation of glycolysis downstream of glucose phosphorylation | 2020 |
|
Ahmed Alshawi
Professor Loranne Agius
| Low metformin causes a more oxidized mitochondrial NADH/NAD redox state in hepatocytes and inhibits gluconeogenesis by a redox-independent mechanism | 2019 |
|
Dr Ziad Al-Oanzi
Sofia Fountana
Tabassum Moonira
Dr Susan Tudhope
John Petrie
et al. | Opposite effects of a glucokinase activator and metformin on glucose-regulated gene expression in hepatocytes | 2017 |
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