Publications by Dr Catherine Arden - ePrints

Browsing publications by Dr Catherine Arden.

Newcastle Authors	Title	Year
Dr Catherine Arden	Autophagy and lysosomal dysfunction in diabetes and its complications	2024
Dr Sherin Bakhashab Rosie Barber Josie O'Neill Dr Catherine Arden Dr Jolanta Weaver et al.	Overexpression of miR-199b-5p in Colony Forming Unit-Hill’s Colonies Positively Mediates the Inflammatory Response in Subclinical Cardiovascular Disease Model: Metformin Therapy Attenuates Its Expression	2024
Dr Sherin Bakhashab Josie O'Neill Rosie Barber Dr Catherine Arden Dr Jolanta Weaver et al.	Upregulation of Anti-Angiogenic miR-106b-3p Correlates Negatively with IGF-1 and Vascular Health Parameters in a Model of Subclinical Cardiovascular Disease: Study with Metformin Therapy	2024
Dr Francesco Zummo Merilin Georgiou Kirsty Cullen Minna Honkanen-Scott Professor James Shaw et al.	Exendin-4 stimulates autophagy in pancreatic β-cells via the RAPGEF/EPAC-Ca2+-PPP3/calcineurin-TFEB axis	2022
Xuefei Yu Dr Catherine Arden Dr Rolando Berlinguer Palmini Dr Chun Chen Carla Bradshaw et al.	Mitochondrial complex I subunit deficiency promotes pancreatic α-cell proliferation	2022
Dr Deborah Cornell Dr Satomi Miwa Dr Maria Georgiou Dr Scott Anderson Minna Honkanen-Scott et al.	Pseudoislet aggregation of pancreatic β-cells improves glucose stimulated insulin secretion by altering glucose metabolism and increasing ATP production.	2022
Amelia Williams Merilin Georgiou Dr Catherine Arden	Autophagy in the pancreas	2021
Tabassum Moonira Dr Shruti Chachra Dr Brian Ford Ahmed Alshawi Dr Catherine Arden et al.	Metformin lowers glucose 6-phosphate in hepatocytes by activation of glycolysis downstream of glucose phosphorylation	2020
Dr Francesco Zummo Dr Catherine Arden	Differential effects of saturated and unsaturated fatty acids on autophagy in pancreatic β-cells.	2019
Dr Catherine Arden	A role for Glucagon-Like Peptide-1 in the regulation of β-cell autophagy	2018
Dr Francesco Zummo Kirsty Cullen Minna Honkanen-Scott Professor James Shaw Professor Penny Lovat et al.	Glucagon-like peptide-1 protects pancreatic beta-cells from death by increasing autophagic flux and restoring lysosomal function	2017
Dr Ziad Al-Oanzi Sofia Fountana Tabassum Moonira Dr Susan Tudhope John Petrie et al.	Opposite effects of a glucokinase activator and metformin on glucose-regulated gene expression in hepatocytes	2017
Dr Francesco Zummo Kirsty Cullen Professor Penny Lovat Professor James Shaw Dr Catherine Arden et al.	Glucagon-like peptide-1 requires EPAC activity to restore autophagy and protect pancreatic beta cells from cell death	2016
Tabassum Moonira Dr Ziad Al-Oanzi Dr Catherine Arden Professor Loranne Agius	Metformin action in hepatocytes is not mimicked by selective activation of AMPactivated protein kinase	2016
Dr Francesco Zummo Kirsty Cullen Professor Penny Lovat Professor James Shaw Dr Catherine Arden et al.	An emerging role for autophagy in the regulation of beta cell survival by glucagon-like peptide-1	2015
Dr Francesco Zummo Kirsty Cullen Professor Penny Lovat Professor James Shaw Dr Catherine Arden et al.	Glucagon-like peptide 1 protects pancreatic beta cells from programmed cell death: a role for autophagy	2015
Kirsty Cullen Dr Ziad Al-Oanzi Professor Loranne Agius Dr Catherine Arden	Glucagon induces translocation of glucokinase from the cytoplasm to the nucleus of hepatocytes by transfer between 6-phosphofructo 2-kinase/fructose 2,6-bisphosphatase-2 and the glucokinase regulatory protein	2014
Dr Catherine Arden Kirsty Cullen Dr Ziad Al-Oanzi Professor Loranne Agius	A role for glucagon in the post-translational regulation of hepatic glucokinase activity	2013
Dr John Petrie Dr Ziad Al-Oanzi Dr Catherine Arden Dr Susan Tudhope Professor Jelena Mann et al.	Glucose induces protein targeting to glycogen in hepatocytes by fructose 2,6-bisphosphate-mediated recruitment of MondoA to the promoter	2013
Dr Susan Tudhope Dr Fiona Malcomson Dr Catherine Arden Dr Laura Hampson Professor Loranne Agius et al.	A Novel Mechanism for Regulating Hepatic Glycogen Synthesis Involving Serotonin and Cyclin-Dependent Kinase-5	2012
Dr Catherine Arden Dr Susan Tudhope Dr Ziad Al-Oanzi Kirsty Cullen Professor Loranne Agius et al.	Fructose 2,6-bisphosphate is essential for glucose-regulated genetranscription of glucose-6-phosphatase and other ChREBP target genes inhepatocytes	2012
Dr Ziad Al-Oanzi Dr John Petrie Dr Susan Tudhope Dr Catherine Arden Professor Loranne Agius et al.	The insulin-independent glucose-induction of the hepatic gluconeogenic enzyme glucose 6-phosphatase involves distinct metabolic pathways and transcription factors	2012
Dr Catherine Arden Dr Susan Tudhope Dr Ziad Al-Oanzi Professor Loranne Agius	Elevated glucose represses liver glucokinase and induces its regulatory protein to safeguard hepatic phosphate homeostasis	2011
Professor Loranne Agius Dr Catherine Arden	Susceptibility of Glucokinase-MODY Mutants to Inactivation by Oxidative Stress in Pancreatic β-Cells	2011
Dr Catherine Arden Claire Marriott	Pseudoislets as primary islet replacements for research: Report on a symposium at King's College London, London UK	2010
Aiman Mahmoud Dr Catherine Arden Dr Audrey Brown Dr Susan Campbell Dr Ali Aldibbiat et al.	Muscle targeted gene therapy for diabetes mellitus: role of proteasomal decay in mutant proinsulin plasmid efficiency	2009
Dr Catherine Arden Kirsty Cullen Professor Loranne Agius	Visualisation of protein-protein interactions of glucokinase in living cells	2009
Dr Catherine Arden Dr Laura Hampson Professor James Shaw Dr Ali Aldibbiat Dr Graham Holliman et al.	A role for PFK-2/FBPase-2, as distinct from fructose 2,6-bisphosphate, in regulation of insulin secretion in pancreatic β-cells	2008
Mohammed Mukhtar Victoria Payne Dr Catherine Arden Dr Andrew Harbottle Professor Loranne Agius et al.	Inhibition of glucokinase translocation by AMP-activated protein kinase is associated with phosphorylation of both GKRP and 6-phosphofructo-2-kinase/ fructose-2,6-bisphosphatase	2008
Dr Catherine Arden Dr Alison Trainer Dr Kathleen Scougall Professor James Shaw Professor Loranne Agius et al.	Cell biology assessment of glucokinase mutations V62M and G72R in pancreatic β-cells: Evidence for cellular instability of catalytic activity	2007
Victoria Payne Dr Catherine Arden Professor Loranne Agius	Contributions of glucokinase and phosphofructokinase-2/fructose bisphosphatase-2 to the elevated glycolysis in hepatocytes from Zucker fa/fa rats	2007
Dr Catherine Arden Professor Loranne Agius	Determination of PFK-2/FBPase-2 isoforms and the role of fructose 2,6 bisphosphate in pancreatic islets and beta-cells lines	2007
Dr Catherine Arden Dr Kathleen Scougall Professor James Shaw Professor Loranne Agius	[abstract] Generation of MIN6 stable cell lines expressing GFP-tagged glucokinase for cellular analysis of glucokinase mutants	2006
Dr Laura Hampson Dr Catherine Arden Professor Loranne Agius	Bioactivity of glycogen phosphorylase inhibitors that bind to the purine nucleoside site	2006
Dr Catherine Arden Professor James Shaw Professor Loranne Agius	Catalytic instability of the glucokinase MODY-2 mutants V62M and G72R in pancreatic beta cells	2006
Dr Catherine Arden Professor Loranne Agius	Glucokinase regulatory protein is associated with mitochondria in hepatocytes	2006
Dr Catherine Arden Dr Laura Hampson Dr Susan Aiston Dr Linda Harndahl Professor Loranne Agius et al.	Increased sensitivity of glycogen synthesis to phosphorylase-a and impaired expression of the glycogen-targeting protein R6 in hepatocytes from insulin-resistant Zucker fa/fa rats	2006
Dr Susan Aiston Dr Laura Hampson Dr Catherine Arden Professor Loranne Agius	The role of protein kinase B/Akt in insulin-induced inactivation of phosphorylase in rat hepatocytes	2006
Victoria Payne Dr Catherine Arden Professor Loranne Agius	Dual role of phosphofructokinase-2/fructose bisphosphatase-2 in regulating the compartmentation and expression of glucokinase in hepatocytes	2005
Dr Catherine Arden Dr Andrew Harbottle Professor Loranne Agius	Glucokinase is an integral component of the insulin granules in glucose-responsive insulin secretory cells and does not translocate during glucose stimulation	2004