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Browsing publications by Dr James Knight.

Newcastle AuthorsTitleYearFull text
Katie Gristwood
Dr Antony Antoniou
Dr Hannah Walden
Dr James Knight
Annealing 1,2,4-triazine to iridium(iii) complexes induces luminogenic behaviour in bioorthogonal reactions with strained alkynes2024
Tracey Luu
Katie Gristwood
Dr James Knight
Click Chemistry: Reaction rates and their suitability for biomedical applications2024
Dr James Knight
In Vivo PET Detection of Lung Micrometastasis in Mice by Targeting Endothelial VCAM-1 Using a Dual-Contrast PET/MRI Probe2024
Dr Toni Pringle
Erik Ramon Gil
Dr Jack Leslie
Professor Fiona Oakley
Professor Matthew Wright
et al.
Synthesis and Preclinical Evaluation of a 89Zr-labelled Human Single Chain Antibody for Non-invasive Detection of Hepatic Myofibroblasts in Acute Liver Injury2024
Katie Gristwood
Dr Saimir Luli
Dr Kenneth Rankin
Dr James Knight
Synthesis and In Vitro Evaluation of a HER2-Specific ImmunoSCIFI Probe2023
Katie Gristwood
Dr Saimir Luli
Dr Kenneth Rankin
Dr James Knight
In situ excitation of BODIPY fluorophores by 89Zr-generated Cerenkov luminescence2022
Dr Toni Pringle
Dr Corey Chan
Dr Saimir Luli
Dr Helen Blair
Dr Kenneth Rankin
et al.
Synthesis and In Vivo Evaluation of a Site-specifically Labeled Radioimmunoconjugate for Dual-Modal (PET/NIRF) Imaging of MT1-MMP in Sarcomas2022
Dr Toni Pringle
Dr Oliver Coleman
Professor Akane Kawamura
Dr James Knight
The influence of degree of labelling upon cellular internalisation of antibody-cell penetrating peptide conjugates2022
Dr James Knight
89Zr-PET imaging of DNA double-strand breaks for the early monitoring of response following alpha- and beta-particle radioimmunotherapy in a mouse model of pancreatic ductal adenocarcinoma2020
Dr Corey Chan
Dr Fabio Nicoli
Marcus Brookes
Zak Gamie
Tom Beckingsale
et al.
Advances in image enhancement for sarcoma surgery2020
Dr James Knight
Early Detection in a Mouse Model of Pancreatic Cancer by Imaging DNA Damage Response Signalling2020
Dr James Knight
Click Chemistry in Radiopharmaceutical Chemistry2019
Dr James Knight
Dual-isotope imaging allows in vivo immunohistochemistry using radiolabelled antibodies in tumours2019
Dr James Knight
PET Imaging of PARP Expression using [18F]olaparib2019
Dr James Knight
Probing the Limits of Q-Tag Bioconjugation of Antibodies2019
Dr James Knight
Targeting phosphatidylserine for radionuclide-based molecular imaging of apoptosis2019
Dr James Knight
Imaging of Claudin-4 in Pancreatic Ductal Adenocarcinoma Using a Radiolabelled Anti-Claudin-4 Monoclonal Antibody2018
Dr James Knight
Preservation of Ligand Functionality by Click Chemistry2018
Dr James Knight
Translational molecular imaging in exocrine pancreatic cancer2018
Dr James Knight
89Zr-anti-gH2AX-TAT but not 18F-FDG allows early monitoring of response to chemotherapy in a mouse model of pancreatic ductal adenocarcinoma2017
Dr James Knight
Imaging the DNA damage response with PET and SPECT2017
Dr James Knight
In Vivo Pretargeted Imaging of HER2 and TAG-72 Expression Using the HaloTag Enzyme2017
Dr James Knight
18F-Labeled wild-type annexin V: Comparison of random and site-selective radiolabeling methods2016
Dr James Knight
Co-ordination behaviour of a novel tristhiourea tripodal ligand; Structural variations in a series of transition metal complexes2016
Dr James Knight
Preclinical 89Zr Immuno-PET of high-grade serous ovarian cancer and lymph node metastasis2016
Dr James Knight
Scaling-down antibody radiolabeling reactions with zirconium-892016
Dr James Knight
Shaping and enforcing coordination spheres: Probing the ability of tripodal ligands to favour trigonal prismatic geometry2016
Dr James Knight
Claudin-4 SPECT imaging allows detection of aplastic lesions in a mouse model of breast cancer2015
Dr James Knight
Development of an enzymatic pretargeting strategy for dual-modality imaging2015
Dr James Knight
PET and SPECT imaging for the acceleration of anti-cancer drug development2015
Dr James Knight
PET imaging of DNA damage using 89Zr-labelled anti-γH2AX-TAT immunoconjugates2015
Dr James Knight
Bioorthogonal chemistry: implications for pretargeted nuclear (PET/SPECT) maging and therapy2014
Dr James Knight
Crystal Structure of the Moonoprotonated Tripodal Ligand 2,2’-bipyrid-6-yl) Methanol2014
Dr James Knight
Imaging DNA damage allows detection of preneoplasia in the BALB-neuT model of breast cancer2014
Dr James Knight
Synthesis, complex stability and small animal PET imaging of a novel 64Cu-labelled cryptand molecule2014
Dr James Knight
Co-ordinative properties of a tripodal trisamide ligand with a capped octahedral preference2013
Dr James Knight
Synthesis and evaluation of an 18F-labelled norbornene derivative for copper-free click chemistry reactions2013
Dr James Knight
Co-ordination behaviour of a novel bisthiourea tripodal ligand: Structural, spectroscopic and electrochemical properties of a series of transition metal complexes2012
Dr James Knight
Synthesis and co-ordination chemistry of tris(picolyl-2-carboxyamido-6- pyridyl) methanol: A ligand with a strong preference for trigonal prismatic geometries2012
Dr James Knight
A facile one-pot synthesis of a new cryptand via a Pd(II)-catalysed carbonylation reaction2010
Dr James Knight
The synthesis and coordination chemistry of a tris-8-aminoquinoline tripodal ligand2009