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Browsing publications by
Dr Florian Gothe.
Newcastle Authors
Title
Year
Full text
Dr Florian Gothe
Qian Zhang
Dr Christopher Duncan
Professor Sophie Hambleton
Human inherited complete STAT2 deficiency underlies inflammatory viral diseases
2023
Dr Florian Gothe
Catherine Hatton
Angela Grainger
Dr Venetia Bigley
Dr Joanna Perthen
et al.
A Novel Case of Homozygous Interferon Alpha/Beta Receptor Alpha Chain (IFNAR1) Deficiency With Hemophagocytic Lymphohistiocytosis
2022
Dr Florian Gothe
Catherine Hatton
Dr Helen Griffin
Dr Christopher Duncan
Professor Sophie Hambleton
et al.
Aberrant inflammatory responses to type I interferon in STAT2 or IRF9 deficiency
2022
Dr Florian Gothe
Professor Sophie Hambleton
STAT5B restrains human B-cell differentiation to maintain humoral immune homeostasis
2022
Dr Aidan Hanrath
Catherine Hatton
Dr Florian Gothe
Connie Browne
Dr Simon Cockell
et al.
Type I Interferon receptor (
IFNAR2
) deficiency reveals Zika virus cytopathicity in human macrophages and microglia
2022
Catherine Hatton
Dr Rachel Botting
Dr Maria Duenas Fadic
Dr Iram Haq
Dr Bernard Verdon
et al.
Delayed induction of type I and III interferons mediates nasal epithelial cell permissiveness to SARS-CoV-2
2021
Dr Florian Gothe
Sophie Howarth
Dr Christopher Duncan
Professor Sophie Hambleton
Monogenic susceptibility to live viral vaccines
2021
Dr Florian Gothe
Professor Sophie Hambleton
The expansion of human T-bet
high
CD21
low
B cells is T cell dependent
2021
Dr Florian Gothe
Dr David McDonald
Dr Meghan Acres
Dr Karin Engelhardt
Professor Sophie Hambleton
et al.
Human interleukin-2 receptor β mutations associated with defects in immunity and peripheral tolerance
2019
Dr Florian Gothe
Emeritus Professor Drew Rowan
Angela Grainger
Professor Andrew Cant
Professor Mary Slatter
et al.
Novel Gain-of-Function Mutation in
Stat1
Sumoylation Site Leads to CMC/CID Phenotype Responsive to Ruxolitinib
2019
Dr Christopher Duncan
Dr Benjamin Thompson
Dr Rui Chen
Dr Florian Gothe
Victoria Shuttleworth
et al.
Severe type I interferonopathy and unrestrained interferon signaling due to a homozygous germline mutation in
STAT2
2019
Dr Meghan Acres
Dr Florian Gothe
Angela Grainger
Andrew Skelton
Dr David Swan
et al.
STAT5B deficiency due to a novel missense mutation in the coiled-coil domain
2018