Publications by Dr David McDonald - ePrints

Browsing publications by Dr David McDonald.

Newcastle Authors	Title	Year
Tegan McTaggart Jing Xuan Lim Dr Katie Smith Bronagh Heaney Dr David McDonald et al.	Deciphering Novel Communication Patterns in T Regulatory Cells From Very Old Adults	2025
Tegan McTaggart Jing Xuan Lim Dr Katie Smith Bronagh Heaney Dr David McDonald et al.	Deep phenotyping of T regulatory cells in psoriatic arthritis highlights targetable mechanisms of disease	2025
Dr Saskia Bos Bethany Hunter Dr David McDonald George Merces Georgia Sheldon et al.	High-dimensional tissue profiling of immune cell responses in chronic lung allograft dysfunction	2025
Dr Amy Vincent Dr Chun Chen Dr Tiago Gomes Bernardino Gomes Dr Valeria Di Leo Kamil Pabis et al.	A stagewise response to mitochondrial dysfunction in mitochondrial DNA maintenance disorders	2024
Dr Luke Milross Bethany Hunter Dr David McDonald George Merces Dr Amanda Thomson et al.	Distinct lung cell signatures define the temporal evolution of diffuse alveolar damage in fatal COVID-19	2024
Patricia Pinol Jurado Jose Verdú-Díaz Esther Fernández-Simón Dr Conor Lawless Dr Amy Vincent et al.	Imaging mass cytometry analysis of Becker muscular dystrophy muscle samples reveals different stages of muscle degeneration	2024
Bethany Hunter Dr Ioana Nicorescu Emma Foster Dr David McDonald Dr Gill Hulme et al.	OPTIMAL: An OPTimized Imaging Mass cytometry AnaLysis framework for benchmarking segmentation and data exploration	2024
Sean Hockney Carly Knill Dr David McDonald Professor Andrew Filby Dr Deepali Pal et al.	Protocol for in vitro co-culture, proliferation, and cell cycle analyses of patient-derived leukemia cells	2024
Dr Ken Baker Dr David McDonald Dr Gill Hulme Raf Hussain Dr Jonathan Coxhead et al.	Single-cell insights into immune dysregulation in rheumatoid arthritis flare versus drug-free remission	2024
Dr Domenico Somma Professor John Isaacs Professor Andrew Filby Dr David McDonald Dr JASMINE Sim et al.	Synovial tissue myeloid dendritic cell subsets exhibit distinct tissue-niche localization and function in health and rheumatoid arthritis	2024
Dr Martina Finetti Bethany Hunter Professor Andrew Filby Dr David McDonald	GBMdeconvoluteR accurately infers proportions of neoplastic and immune cell populations from bulk glioblastoma transcriptomics data	2023
Dr Dino Masic Kayleigh Fee Dr Hayden Bell Marian Case Juan Ojeda Garcia et al.	Hyperactive CREB subpopulations increase during therapy in pediatric B-lineage acute lymphoblastic leukemia	2023
Dr Chun Chen Dr David McDonald Dr Alasdair Blain Emily Mossman Kiera Atkin et al.	Parkinson’s disease neurons exhibit alterations in mitochondrial quality control proteins	2023
Jing Xuan Lim Grace Mallett Dr David McDonald Dr Gill Hulme Dr Stephanie Laba et al.	Programmed cell death-1 receptor-mediated regulation of Tbet⁺NK1.1^- innate lymphoid cells within the tumor microenvironment	2023
Dr Kathryn Musgrave Dr Jonathan Scott Dr Wezi Sendama Aaron Gardner Fiona Dewar et al.	Tissue factor expression in monocyte subsets during human immunothrombosis, endotoxemia and sepsis	2023
Dr Chun Chen Emily Mossman Dr David McDonald Dr Alasdair Blain Laura Bone et al.	Astrocytic Changes in Mitochondrial Oxidative Phosphorylation Protein Levels in Parkinson's Disease	2022
Dr Jack Leslie Erik Ramon Gil Kathryn Gilroy Dr Saimir Luli Maja Laszczewska et al.	CXCR2 inhibition enables NASH-HCC immunotherapy	2022
Dan Hipps Dr Philip Dobson Dr Charlotte Warren Dr David McDonald Andrew Fuller et al.	Detecting respiratory chain defects in osteoblasts from osteoarthritic patients using imaging mass cytometry	2022
Dr Laura Jardine Dr Simone Webb Issac Goh Kai'en Dr Gary Reynolds Dr Michael Mather et al.	Blood and immune development in human fetal bone marrow and Down syndrome	2021
Dr Gary Reynolds Dr Peter Vegh Dr James Fletcher Dr Beth Poyner Dr Emily Stephenson et al.	Developmental cell programs are co-opted in inflammatory skin disease	2021
Dr Chun Chen Dr David McDonald Dr Alasdair Blain Dr Ashwin Sachdeva Laura Bone et al.	Imaging mass cytometry reveals generalised deficiency in OXPHOS complexes in Parkinson’s disease	2021
Dr Charlotte Warren Dr David McDonald Professor David Deehan Professor Robert Taylor Professor Andrew Filby et al.	Decoding mitochondrial heterogeneity in single muscle fibres by imaging mass cytometry	2020
Dr Dorin-Mirel Popescu Dr Rachel Botting Dr Emily Stephenson Dr Kile Green Dr Simone Webb et al.	Decoding human fetal liver haematopoiesis	2019
Dr Florian Gothe Dr David McDonald Dr Meghan Acres Dr Karin Engelhardt Professor Sophie Hambleton et al.	Human interleukin-2 receptor β mutations associated with defects in immunity and peripheral tolerance	2019
Dr Laura Jardine Dr Sarah Wiscombe Dr Gary Reynolds Dr David McDonald Andrew Fuller et al.	Lipopolysaccharide inhalation recruits monocytes and dendritic cell subsets to the alveolar airspace.	2019
Dr David McDonald Dr Lindsay Nicholson Professor Anne Dickinson Professor Andrew Filby Dr Xiao Wang et al.	Global phenotypic characterisation of human platelet lysate expanded MSCs by high-throughput flow cytometry	2018
Dr Gary Reynolds James Fletcher Dr Laura Jardine David Dixon Dr Emily Stephenson et al.	Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors	2017
Dr David McDonald Dr Bernadette Carroll Nicholas Robertson Dr Helen Griffin Professor Jeremy Lakey et al.	Dual Proteolytic Pathways Govern Glycolysis and Immune Competence	2014
Professor Sophie Hambleton Dr David McDonald Dr Helen Griffin Angela Grainger Dr Louise Reynard et al.	Autosomal recessive combines immunodeficiency due to loss of function mutation in Tripeptidyl Peptidase II	2012
Dr Helen Griffin Dr David McDonald Dr Rachel Dickinson Angela Grainger Dr Louise Reynard et al.	Whole exome sequencing as a diagnostic tool in primary immunodeficiency	2012
Dr Rachel Dickinson Dr Helen Griffin Dr Venetia Bigley Dr Louise Reynard Raf Hussain et al.	Exome sequencing identifies GATA-2 mutation as the cause of dendritic cell, monocyte, B and NK lymphoid deficiency	2011
Dr David McDonald Dr Helen Griffin Angela Grainger Dr Louise Reynard Professor John Loughlin et al.	Whole-exome deep sequencing identifies a novel causative mutation in primary immunodeficiency	2011
Professor Sophie Hambleton Professor Andrew Cant Professor Andrew Gennery Dr David McDonald	A novel human immunodeficiency disorder associated with a mutation in the T cell receptor a subunit constant gene (TRAC)	2010
Dr David McDonald Professor Heather Cordell Dr Peter Donaldson Professor Simon Pearce	The tryptophan 620 allele of the lymphoid tyrosine phosphatase (PTPN22 gene) predisposes to autoimmune Addison's disease	2009
Dr David McDonald Professor Simon Pearce	Thyroid peroxidase forms thionamide-sensitive homodimers: relevance for immunomodulation of thyroid autoimmunity	2009
Professor Simon Pearce Dr David McDonald	Polymorphisms in CLEC16A and CIITA at 16p13 are associated with primary adrenal insufficiency	2008