Dr Matthew Barter Andrew Skelton Dr Carole Proctor Professor David Young
| DNA methylation analysis identifies key transcription factors involved in mesenchymal stem cell osteogenic differentiation | 2023 |
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Jessica Tarn Sarah Charlton Andrew Skelton Dr Matthew Barter Professor David Young et al. | Regulation of microRNA-221, -222, -21 and -27 in articular cartilage subjected to abnormal compressive forces | 2021 |
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Dr Ahlam Alqahtani Andrew Skelton Dr Lorraine Eley Dr Srinivas Annavarapu Professor Deborah Henderson et al. | Isolation and next generation sequencing of archival formalin-fixed DNA | 2020 |
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Sam Charlton Kat Cheung Yao Hao Dr Jamie Soul Dr Louise Reynard et al. | microRNA-seq of cartilage reveals an over-abundance of miR-140-3p which contains functional isomiRs | 2020 |
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Bola Ajekigbe Kat Cheung Dr Yaobo Xu Andrew Skelton Dr Andreas Panagiotopoulos et al. | Identification of long non-coding RNAs expressed in knee and hip osteoarthritic cartilage | 2019 |
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Laura Ridgley Dr Amy Anderson Dr Nicola Maney Najib Naamane Andrew Skelton et al. | IL-6 Mediated Transcriptional Programming of Naïve CD4+ T Cells in Early Rheumatoid Arthritis Drives Dysregulated Effector Function | 2019 |
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Dr Ken Baker Andrew Skelton Dr Dennis Lendrem Adam Scadeng Dr Ben Thompson et al. | Predicting drug-free remission in rheumatoid arthritis: A prospective interventional cohort study | 2019 |
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Dr Sarah Rice Maria Tselepi Dr Tony Sorial Guillaume Aubourg Dr Colin Shepherd et al. | Prioritization of PLEC and GRINA as osteoarthritis risk genes through the identification and characterization of novel methylation quantitative trait loci | 2019 |
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Jessica Tarn Dr Nadia Howard-Tripp Dr Dennis Lendrem Andrew Skelton Dr Katherine James et al. | Symptom-based stratification of patients with primary Sjögren's syndrome: multi-dimensional characterisation of international observational cohorts and reanalyses of randomised clinical trials | 2019 |
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Dr Nishanthi Thalayasingam Andrew Skelton Dr Amy Anderson Alex Clark Julie Diboll et al. | CD4+ and B lymphocyte expression quantitative traits at rheumatoid arthritis risk loci in untreated early arthritis: implications for causal gene identification | 2018 |
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Chris Macdonald Dr Adrian Falconer Dr Chun Chan Dr David Wilkinson Andrew Skelton et al. | Cytokine-induced cysteine- serine-rich nuclear protein-1 (CSRNP1) selectively contributes to MMP1 expression in human chondrocytes | 2018 |
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Dr Christopher Duncan Angela Grainger Andrew Skelton Raf Hussain Dr Joe Willet et al. | Early-onset autoimmune disease due to a heterozygous loss-of-function mutation in TNFAIP3 (A20) | 2018 |
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Dr Colin Shepherd Dr Dongxing Zhu Andrew Skelton Dr Louise Reynard Professor John Loughlin et al. | Functional characterization of the osteoarthritis genetic risk residing at ALDH1A2 identifies rs12915901 as a key target variant. | 2018 |
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Dr Sarah Rice Dr Tony Sorial Guillaume Aubourg Dr Colin Shepherd Maria Tselepi et al. | Identification of novel methylation quantitative trait loci (mqtls) and functional characterization using CRISPR/CAS9 and gene expression analysis prioritizes PLEC as an OA risk gene | 2018 |
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Dr Faye Cooles Dr Amy Anderson Andrew Skelton Dr Arthur Pratt Professor Iain McInnes et al. | Phenotypic and transcriptomic analysis of peripheral blood plasmacytoid and conventional dendritic cells in early drug naïve rheumatoid arthritis | 2018 |
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Dr Meghan Acres Dr Florian Gothe Angela Grainger Andrew Skelton Dr David Swan et al. | STAT5B deficiency due to a novel missense mutation in the coiled-coil domain | 2018 |
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Dr David Wilkinson Andrew Skelton Emeritus Professor Nick Europe-Finner Emeritus Professor Drew Rowan
| Cytokine-induced MMP13 Expression in Human Chondrocytes Is Dependent on Activating Transcription Factor 3 (ATF3) Regulation. | 2017 |
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Dr Colin Shepherd Dr Dongxing Zhu Andrew Skelton Dr Louise Reynard Professor John Loughlin et al. | Functional characterisation of the osteoarthritis genetic risk locus that resides at the gene ALDH1A2, coding for the retinoic acid synthesis enzyme RALDH2, identifies rs4646636 and rs12915901 as key target SNPs | 2017 |
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Dr Louise Reynard Andrew Skelton David Young Professor John Loughlin
| The first international workshop on the epigenetics of osteoarthritis | 2017 |
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Dr Matthew Barter Dr Rodolfo Gomez Kat Cheung Andrew Skelton Dr Yaobo Xu et al. | The long non-coding RNA ROCR contributes to SOX9 expression and chondrogenic differentiation of human mesenchymal stem cells | 2017 |
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Andrew Skelton Dr Rodolfo Gomez Professor John Loughlin Dr Louise Reynard
| Age-related DNA methylation changes in normal and osteoarthritis cartilage | 2016 |
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Dr Colin Shepherd Andrew Skelton Dr Michael Rushton Dr Louise Reynard Professor John Loughlin et al. | Expression analysis of the osteoarthritis genetic susceptibility locus mapping to an intron of the MCF2L gene and marked by the polymorphism rs11842874 | 2016 |
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Dr Arthur Pratt Dr Amy Anderson Julie Diboll Andrew Skelton Dr Dennis Lendrem et al. | Identification of novel expression quantitative trait loci in CD4+ T cells of untreated early arthritis patients | 2016 |
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Dr Rachel Williams Andrew Skelton Dr Stephen Todryk Emeritus Professor Drew Rowan Professor Philip Preshaw et al. | Leptin and Pro-Inflammatory Stimuli Synergistically Upregulate MMP-1 and MMP-3 Secretion in Human Gingival Fibroblasts | 2016 |
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Dr Matthew Barter Kat Cheung Dr Yaobo Xu Andrew Skelton Professor David Young et al. | Long noncoding RNA ROCR is essential for chondrogenic differentiation of mesenchymal stem cells | 2016 |
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Dr Colin Shepherd Andrew Skelton Dr Michael Rushton Dr Louise Reynard Professor John Loughlin et al. | Expression analysis of the osteoarthritis genetic susceptibility locus mapping to an intron of the MCF2L gene and marked by the polymorphism rs11842874 | 2015 |
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Dr Arthur Pratt Dr Amy Anderson Julie Diboll Andrew Skelton Ben Hargreaves et al. | The Importance of IL-6-STAT3 Mediated Activation of Circulating CD4+ T Cells in the Pathogenesis of Early Seronegative Rheumatoid Arthritis: A Validation Study | 2015 |
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Shereen Al-Ali Dr Simon Cockell Andrew Skelton Dr Katherine James Jessica Tarn et al. | Identification of Whole Blood Gene Expression Signature in Primary Sjogren's Syndrome Associated Lymphoma | 2014 |
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