Catriona Manville Kayleigh Smith Dr Zbyslaw Sondka Holly Rance Dr Ian Cowell et al. | Genome-wide ChIP-seq analysis of human TOP2B occupancy in MCF7 breast cancer epithelial cells | 2015 |
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Dr Katrin Jaedicke Dr Kay Padget Dr Stephen Todryk Professor Philip Preshaw Dr John Taylor et al. | Leptin up-regulates TLR2 in human monocytes | 2013 |
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Dr Ian Cowell Dr Zbyslaw Sondka Kayleigh Smith Ka Lee Catriona Manville et al. | Model for MLL translocations in therapy-related leukemia involving topoisomerase IIβ-mediated DNA strand breaks and gene proximity | 2012 |
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Dr Kay Padget Hannah Curtis Dr Ian Cowell Dr Zbyslaw Sondka Dr Nick Morris et al. | MRE11 facilitates the removal of human topoisomerase II complexes from genomic DNA | 2012 |
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Dr Ian Cowell Dr Nikolaos Papageorgiou Dr Kay Padget Professor Caroline Austin
| Histone deacetylase inhibition redistributes topoisomerase IIβ from heterochromatin to euchromatin | 2011 |
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Catriona Manville Dr Emma Clark Dr Kay Padget james Harvey Dr Nick Morris et al. | Bioinformatic analysis of topoisomerase II binding sites | 2007 |
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Dr Miguel Lopez-Lazaro Dr Elaine Willmore Andrew Jobson Kathryn Gilroy Hannah Curtis et al. | Curcumin induces high levels of topoisomerase I- and II-DNA complexes in K562 leukemia cells | 2007 |
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Kathryn Gilroy Chrysoula Leontiou Dr Kay Padget Professor Jeremy Lakey Professor Caroline Austin et al. | mAMSA resistant human topoisomerase IIβ mutation G465D has reduced ATP hydrolysis activity | 2006 |
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Dr Kay Padget Professor Caroline Austin
| Deacetylase activity associates with topoisomerase II and is necessary for etoposide-induced apoptosis | 2001 |
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Dr Kay Padget Dr Michael Tilby Professor Caroline Austin
| An investigation into the formation of N- [2-(dimethylamino)ethyl]acridine-4-carboxamide (DACA) and 6-[2-(dimethylamino)ethylamino]- 3-hydroxy-7H-indeno[2,1-C]quinolin-7-one dihydrochloride (TAS-103) stabilised DNA topoisomerase I and II cleavable complexes in human leukaemia cells | 2000 |
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Dr Kay Padget Professor Andrew Pearson Dr Michael Tilby Professor Caroline Austin
| Camptothecin-stabilised topoisomerase I-DNA complexes in leukaemia cells visualised and quantified in situ by the TARDIS assay (trapped in agarose DNA immunostaining) | 2000 |
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Dr Kay Padget Professor Andrew Pearson Professor Caroline Austin
| Quantitation of DNA topoisomerase II alpha and beta in human leukaemia cells by immunoblotting | 2000 |
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Dr Kay Padget Professor Andrew Pearson Professor Caroline Austin
| Quantitation of DNA topoisomerase IIalpha and beta in human leukaemia cells by immunoblotting | 2000 |
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Dr Elaine Willmore Dr Adrian Frank Dr Kay Padget Dr Michael Tilby Professor Caroline Austin et al. | Etoposide targets topoisomerase IIα and IIβ in leukemic cells: Isoform-specific cleavable complexes visualized and quantified in situ by a novel immunofluorescence technique | 1998 |
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