Publications by Professor Tom Strachan - ePrints

Browsing publications by Professor Tom Strachan.

Newcastle Authors	Title	Year
Dr Irina Neganova Dr Stuart Atkinson Dr George Anyfantis Dr Owen Hughes Professor Tom Strachan et al.	A role for NANOG in G1 to S transition in human embryonic stem cells through direct binding of CDK6 and CDC25A	2009
Dr Rebecca Stewart Dr Chunbo Yang Dr George Anyfantis Dr Nicholas Hole Professor Tom Strachan et al.	Silencing of the expression of pluripotent driven-reporter genes stably transfected into human pluripotent cells	2008
Dr Vlad Seitan Dr Andrew Banks Dr Steven Laval Dr Sarah Newbury Professor Tom Strachan et al.	Metazoan Scc4 homologs link sister chromatid cohesion to cell and axon migration guidance	2006
Dr Subrot Sarma Dr Janet Kerwin Mark Scott Professor Tom Strachan Emerita Professor Susan Lindsay et al.	3D modelling, gene expression mapping and post-mapping image analysis in the developing human brain	2005
Petra Stojkovic Professor Majlinda Lako Dr Rebecca Stewart Professor Lyle Armstrong Jerome Evans et al.	An autogeneic feeder cell system that efficiently supports growth of undifferentiated human embryonic stem cells	2005
Petra Stojkovic Professor Majlinda Lako Dr Rebecca Stewart Professor Lyle Armstrong Professor Mary Herbert et al.	An Autogeneic Feeder Cell System That Efficiently Supports Growth of Undifferentiated Human Embryonic Stem Cells	2005
Professor Tom Strachan	Cornelia de Lange Syndrome and the link between chromosomal function, DNA repair and developmental gene regulation	2005
Dr Louise Hyslop Professor Miodrag Stojkovic Professor Lyle Armstrong Theresia Walter Petra Stojkovic et al.	Downregulation of NANOG induces differentiation of human embryonic stem cells to extraembryonic lineages	2005
Dr Sajjad Ahmad Professor Lyle Armstrong Professor Miodrag Stojkovic Ian Dimmick Dr Louise Hyslop et al.	The identification and characterisation of human corneal epithelial progenitors on the basis of high aldehyde dehydrogenase activity	2005
Dr Janet Kerwin Mark Scott Professor Steve Robson Professor Tom Strachan Emerita Professor Susan Lindsay et al.	3 dimensional modelling of early human brain development using optical projection tomography	2004
Professor Steve Robson Dr Janet Kerwin Mark Scott Professor Tom Strachan Emerita Professor Susan Lindsay et al.	3-dimensional modelling of human development using optical projection tomography	2004
Dr Emma Tonkin Pieter Eichhorn Burhan Imamwerdi Emerita Professor Susan Lindsay Dr Michael Jackson et al.	A giant novel gene undergoing extensive alternative splicing is severed by a Cornelia de Lange-associated translocation breakpoint at 3q26.3	2004
Dr Lorraine Eley Lee Turnpenny Dr Laura Yates Scott Craighead David Morgan et al.	A perspective on inversin	2004
Professor Miodrag Stojkovic Professor Majlinda Lako Petra Stojkovic Dr Rebecca Stewart Professor Lyle Armstrong et al.	Derivation of human embryonic stem cells from day-8 blastocysts recovered after three-step in vitro culture	2004
Professor Miodrag Stojkovic Professor Majlinda Lako Professor Tom Strachan Professor Alison Murdoch	Derivation, growth and applications of human embryonic stem cells	2004
Dr Sajjad Ahmad Dr Louise Hyslop Professor Colin Jahoda Professor Tom Strachan Professor Majlinda Lako et al.	From embryo to eye - Human embryonic stem cell markers OCT-4 and NANOG are localised to adult limbal epithelium	2004
Emerita Professor Susan Lindsay Mark Scott Dr Subrot Sarma Moira Crosier Dr Steven Lisgo et al.	Human developmental gene expression: an important link between disorder and understanding	2004
Dr Emma Tonkin Tzu-Jou Wang Dr Steven Lisgo Professor Tom Strachan	NIPBL, encoding a homolog of fungal Scc2-type sister chromatid cohesion proteins and fly Nipped-B, is mutated in Cornelia de Lange syndrome	2004
Dr Subrot Sarma Emerita Professor Susan Lindsay Professor Tom Strachan Professor Steve Robson	Stability of RNA in human embryos stored over long periods of time	2004
Dr Emma Tonkin Emerita Professor Susan Lindsay Professor Tom Strachan	A giant gone encoding a developmentally regulated novel member of the M28 peptidase family is severed by a Cornelia de Lange-associated translocation breakpoint at 3q26.3	2003
Professor Tom Strachan Dr Emma Tonkin	Genome-wide linkage analysis identifies five candidate gene regions in the Cornelia de Lange syndrome (CdLS)	2003
Professor Judith Goodship Professor Tom Strachan	Inversin mutations cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determination	2003
Professor Judith Goodship Professor Tom Strachan	Mutations in Inversin cause Nephronophthisis type 2, linking cystic kidney disease to the function of primary cilia and left-right axis determination	2003
Professor Judith Goodship Professor Tom Strachan	Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determination	2003
Professor Tom Strachan	Towards effective and rewarding data sharing	2003
Dr Maria Lastowska Simon Cotterill Natalie Bown Professor John Lunec Professor Tom Strachan et al.	Breakpoint position on 17q identifies the most aggressive neuroblastoma tumors	2002
Dr Steven Lisgo Professor Deborah Henderson Professor Tom Strachan Emerita Professor Susan Lindsay	Craniofacial expression of human and murine TBX22 correlates with the cleft palate and ankyloglossia phenotype observed in CPx patients	2002
David Morgan Dr Lorraine Eley Professor John Sayer Professor Tom Strachan Dr Laura Yates et al.	Expression analyses and interaction with the anaphase promoting complex protein Apc2 suggest a role for inversin in primary cilia and involvement in the cell cycle	2002
Catriona Munro Professor Tom Strachan	Hailey-Hailey disease: Molecular and clinical characterization of novel mutations in the ATP2C1 gene	2002
Dr Emma Tonkin Dr Donna Hagan Weiping Li Professor Tom Strachan	Identification and characterisation of novel mammalian homologues of Drosophila polyhomeotic permits new insights into relationships between members of the polyhomeotic family	2002
Professor Judith Goodship Lee Turnpenny Professor Tom Strachan	The left-right determinant inversin has highly conserved ankyrin repeat and IQ domains and interacts with calmodulin	2002
Dr Emma Tonkin Pieter Eichhorn Dr Donna Hagan Dr Meryl Lusher Dr Maggie Ireland et al.	A novel gene is disrupted by a Cornelia de Lange-associated translocation breakpoint at 3q26.3	2001
Dr Emma Tonkin Professor Tom Strachan	Exclusion of linkage to the CDL1 gene region on chromosome 3q26.3 in some familial cases of Cornelia de Lange Syndrome	2001
Dr Maria Lastowska Dr Nicholas Bown Professor John Lunec Professor Tom Strachan Professor Andrew Pearson et al.	Molecular cytogenetic definition of 17q translocation breakpoints in neuroblastoma	2001
Dr Maria Lastowska Dr Nicholas Bown Professor John Lunec Professor Tom Strachan Professor Andrew Pearson et al.	Molecular cytogenetic definition of 17q translocation breakpoints in neuroblastoma	2001
Dr Sally Lynch Ying Wang Professor Tom Strachan Professor Sir John Burn Emerita Professor Susan Lindsay et al.	Autosomal dominant sacral agenesis: Currarino syndrome	2000
Professor Tom Strachan	Clinical and molecular correlates of somatic mosaicism in neurofibromatosis 2	2000
Simon Carter Dr Eugene Healy Professor Tom Strachan	Hailey-Hailey disease is caused by mutations in ATP2C1 encoding a novel Ca2+ pump	2000
Emerita Professor Susan Lindsay Professor Steve Robson Professor Tom Strachan	Human-mouse differences in the embryonic expression patterns of developmental control genes and disease genes	2000
Dr Donna Hagan Alison Ross Professor Tom Strachan Dr Sally Lynch Dr Victor Ruiz-Perez et al.	Mutation analysis and embryonic expression of the HLXB9 Currarino syndrome gene	2000
Dr Donna Hagan Alison Ross Professor Tom Strachan Dr Victor Ruiz-Perez Emerita Professor Susan Lindsay et al.	Mutation analysis anti embryonic expression of the HLXB9 currarino syndrome gene	2000
Dr Neil Hanley Dr Donna Hagan Dr Mark Clement-Jones Dr Stephen Ball Professor Tom Strachan et al.	SRY, SOX9, and DAX1 expression patterns during human sex determination and gonadal development	2000
Dr Mark Clement-Jones Professor Steve Robson Professor Tom Strachan Emerita Professor Susan Lindsay	The short stature homeobox gene SHOX is involved in skeletal abnormalities in Turner syndrome	2000
Dr Victor Ruiz-Perez Simon Carter Dr Eugene Healy Carole Todd Professor Jonathan Rees et al.	ATP2A2 mutations in Darier's disease: Variant cutaneous phenotypes are associated with missense mutations, but neuropsychiatric features are independent of mutation class	1999
Dr Victor Ruiz-Perez Simon Carter Dr Eugene Healy Professor Jonathan Rees Professor Tom Strachan et al.	Classical and variant Darier disease due to mutation in ATP2A2	1999
Dr Elizabeth Jones Dr Mark Clement-Jones Emerita Professor Susan Lindsay Professor Tom Strachan Professor Steve Robson et al.	Embryonic alphafetoprotein expression: Significant human and mouse differences	1999
Dr Victor Ruiz-Perez Simon Carter Carole Todd Professor Jonathan Rees Professor Tom Strachan et al.	Expression of SERCA2 isoforms in skin, and mutations in Darier's disease	1999
Dr Neil Hanley Dr Stephen Ball Dr Mark Clement-Jones Dr Donna Hagan Professor Tom Strachan et al.	Expression of steroidogenic factor 1 and Wilms' tumour 1 during early human gonadal development and sex determination	1999
Emerita Professor Susan Lindsay Dr Mark Clement-Jones Professor Steve Robson Professor Tom Strachan	Expression of the short stature homeobox gene, SHOX, correlates with skeletal abnormalities in Turner syndromece	1999
Dr Meryl Lusher Dr Maggie Ireland Professor Tom Strachan	Genomic organisation of the human chordin gene and mutation screening of candidate Cornelia de Lange syndrome genes	1999
Dr Neil Hanley Dr Karen Piper Hanley Dr Stephen Ball Dr Mark Clement-Jones Professor Tom Strachan et al.	High level SOX9 expression during development of the human embryonic pancreas is associated with abnormal islet formation in a case of Campomelic Dysplasia.	1999
Professor Tom Strachan	Human Molecular Genetics	1999
Dr Donna Hagan Dr Steven Lisgo Professor Tom Strachan Dr Mark Clement-Jones Professor Steve Robson et al.	Mapping gene expression domains and neuronal cell differentiation during human embryonic forebrain development	1999
Professor Majlinda Lako Professor Tom Strachan	Mutation screening in British 21-hydroxylase deficiency families and development of novel microsatellite based approaches to prenatal diagnosis	1999
Dr Victor Ruiz-Perez Professor Tom Strachan	Mutations in ATP2A2, encoding a Ca2+ pump, cause Darier disease	1999
Professor Tom Strachan	Probability of bilateral disease in people presenting with a unilateral vestibular schwannoma	1999
Dr Emma Tonkin Professor Tom Strachan	The Cornelia de Lange syndrome; Cytogenetic and molecular analysis, with exclusion of linkage to chromosome 3q in some familial cases	1999
Dr Victor Ruiz-Perez Dr Donna Hagan Dr Sally Lynch Emerita Professor Susan Lindsay Dr David Wilson et al.	A homeobox gene, HLXB9, is the major locus for dominantly inherited sacral agenesis	1998
Dr Maria Lastowska Dr Nicholas Bown Professor John Lunec Professor Tom Strachan Professor Andrew Pearson et al.	Molecular cytogenetic delineation of 17q translocation breakpoints in neuroblastoma cell lines	1998
Simon Carter Dr Victor Ruiz-Perez Professor Jonathan Rees Professor Tom Strachan	Refined genetic mapping of the Darier locus to a <1-cM region of chromosome 12q24.1, and construction of a complete, high-resolution P1 artificial chromosome/bacterial artificial chromosome contig of the critical region	1998