Publications by Dr Roger Searle - ePrints

Browsing publications by Dr Roger Searle.

Newcastle Authors	Title	Year
Dr Harry Otun Barbara Innes Dr Gendie Lash Dr Elizabeth Ball Dr Roger Searle et al.	Quantification of spiral artery remodelling using an Adobe Photoshop-based technique	2019
Dr Craig Nesbitt Professor Alexander Phillips Dr Roger Searle Professor Gerard Stansby	Randomized Trial to Assess the Effect of Supervised and Unsupervised Video Feedback on Teaching Practical Skills	2015
Dr Meenakshi Swamy Dr Hernaik Singh Dr Roger Searle	Role of SimMan in teaching clinical skills to preclinical medical students	2013
Dr Meenakshi Swamy Dr Roger Searle	Anatomy teaching with portable ultrasound to medical students	2012
Dr Dorota Overbeck-Zubrzycka Amaran Krishnan David Hamilton Dr Roger Searle Professor Gerard Stansby et al.	Tomorrow’s Doctors: students’ satisfaction with a prosection-based undergraduate anatomy course	2012
Dr Harry Otun Dr Gendie Lash Barbara Innes Dr Judith Bulmer Dr Katsuhiko Naruse et al.	Effect of tumour necrosis factor-alpha in combination with interferon-gamma on first trimester extravillous trophoblast invasion	2011
Dr Gendie Lash Dr Katsuhiko Naruse Dr Andrew Robson Barbara Innes Dr Roger Searle et al.	Interaction between uterine natural killer cells and extravillous trophoblast cells: effect on cytokine and angiogenic growth factor production	2011
Dr Gendie Lash Dr Katsuhiko Naruse Dr Andrew Robson Barbara Innes Dr Roger Searle et al.	Interaction between uterine natural killer cells and extravillous trophoblast cells: effect on cytokine and angiogenic growth factor production	2011
Dr Gendie Lash Dr Harry Otun Barbara Innes Dr Roger Searle Professor Steve Robson et al.	Regulation of extravillous trophoblast invasion by uterine natural killer cells is dependent on gestational age	2010
Dr Gendie Lash Dr Judith Bulmer Barbara Innes Dr Roger Searle Professor Steve Robson et al.	Role of Interleukin 8 in Uterine Natural Killer Cell Regulation of Extravillous Trophoblast Cell Invasion	2010
Dr Gendie Lash Dr Katsuhiko Naruse Barbara Innes Professor Steve Robson Dr Roger Searle et al.	Secretion of Angiogenic Growth Factors by Villous Cytotrophoblast and Extravillous Trophoblast in Early Human Pregnancy	2010
Dr Katsuhiko Naruse Barbara Innes Dr Judith Bulmer Professor Steve Robson Dr Roger Searle et al.	Secretion of cytokines by villous cytotrophoblast and extravillous trophoblast in the first trimester of human pregnancy	2010
Dr Judith Bulmer Dr Roger Searle Barbara Innes Professor Steve Robson	Altered decidual leucocyte populations in the placental bed in pre-eclampsia and foetal growth restriction: a comparison with late normal pregnancy	2009
Dr Roger Searle Professor Steve Robson Barbara Innes Dr Judith Bulmer	Decidual leucocyte populations in early to late gestation normal human pregnancy	2009
Dr Katsuhiko Naruse Dr Gendie Lash Barbara Innes Dr Harry Otun Dr Roger Searle et al.	Localization of matrix metalloproteinase (MMP)-2, MMP-9 and tissue inhibitors for MMPs (TIMPs) in uterine natural killer cells in early human pregnancy	2009
Dr Katsuhiko Naruse Dr Gendie Lash Dr Judith Bulmer Barbara Innes Dr Harry Otun et al.	The Urokinase Plasminogen Activator (uPA) System in Uterine Natural Killer Cells in the Placental Bed During Early Pregnancy	2009
Dr Leandro Oliveira Dr Gendie Lash Dr Judith Bulmer Barbara Innes Dr Roger Searle et al.	HLA-G does not alter uterine natural killer cell secretion of cytokines	2008
Dr Gendie Lash Barbara Innes Dr Roger Searle Dr Judith Bulmer	uNK Cells Effect on Trophoblast Cell Invasion Involves IL-8 Secretion and the Mechanism of Action Involves Changes on Apoptosis	2008
Dr Katsuhiko Naruse Dr Gendie Lash Barbara Innes Dr Leandro Oliveira Dr Harry Otun et al.	Cytokine secretion by uterine natural killer cells in coculture with extravillous trophoblast	2007
Dr Gendie Lash Maureen Kirkley Dr Roger Searle Professor Steve Robson Dr Judith Bulmer et al.	Effect of Low Oxygen Concentrations on Trophoblast-Like Cell Line Invasion	2007
Dr Roger Searle	Interleukin-17 Expression in the Human Placenta	2007
Dr Leandro Oliveira Dr Gendie Lash Dr Harry Otun Barbara Innes Dr Katsuhiko Naruse et al.	Uterine natural killer cell stimulation of trophoblast invasion is only partially dependent on IL-8 production	2007
Dr Katsuhiko Naruse Dr Gendie Lash Barbara Innes Dr Harry Otun Dr Leandro Oliveira et al.	Uterine natural killer cells disrupt vascular smooth muscle structure in vitro: A role in spiral artery remodelling?	2007
Dr Gendie Lash Barbara Innes Dr Harry Otun Professor Steve Robson Dr Roger Searle et al.	Comparison of three multiplex cytokine analysis systems: Luminex, SearchLight™ and FAST Quant®	2006
Dr Judith Bulmer Professor Steve Robson Barbara Innes Dr Roger Searle	Effector activity of decidual CD8⁺ T lymphocytes in early human pregnancy	2006
Dr Gendie Lash Maureen Kirkley Barbara Innes Dr Roger Searle Professor Steve Robson et al.	Expression of angiogenic growth factors by uterine natural killer cells during early pregnancy	2006
Dr Gendie Lash Dr Harry Otun Barbara Innes Maureen Kirkley Dr Roger Searle et al.	Interferon-γ inhibits extravillous trophoblast cell invasion by a mechanism that involves both changes in apoptosis and protease levels	2006
Dr Katsuhiko Naruse Dr Gendie Lash Barbara Innes Dr Judith Bulmer Dr Harry Otun et al.	Localization of proteases in uterine natural killer cells in the placental bed during early pregnancy	2006
Dr Gendie Lash Dr Harry Otun Barbara Innes Dr Judith Bulmer Dr Roger Searle et al.	Low oxygen concentrations inhibit trophoblast cell invasion from early gestation placental explants via alterations in levels of the urokinase plasminogen activator system	2006
Dr Gendie Lash Barbara Innes Dr Roger Searle Professor Steve Robson Dr Judith Bulmer et al.	Secretion of angiogenic growth factors by uterine natural killer cells.	2006
Dr Katsuhiko Naruse Dr Gendie Lash Barbara Innes Dr Judith Bulmer Dr Roger Searle et al.	Secretion of matrix metalloproteinase (MMP) 2 and 9 and urokinase plasminogen activator (uPA) by decidual cell fractions in early pregnancy	2006
Dr Gendie Lash Barbara Innes Dr Judith Bulmer Dr Roger Searle Professor Steve Robson et al.	Uterine natural killer cell cytokine secretion profile	2006
Barbara Innes Dr Gendie Lash Professor Steve Robson Dr Roger Searle Dr Judith Bulmer et al.	[abstract] Uterine NK cells persist after theist trimester but fewer express perforin and granzyme B	2005
Paula Scaife Dr Judith Bulmer Barbara Innes Professor Steve Robson Dr Roger Searle et al.	Assessment of the cytolytic capability of decidual CD8+T lymphocytes in normal early pregnancy	2005
Dr Harry Otun Dr Judith Bulmer Dr Gendie Lash Barbara Innes Dr Roger Searle et al.	Gestational changes in spiral artery vascular smooth muscle content using photoshop based image analysis	2005
Dr Harry Otun Dr Gendie Lash Barbara Innes Dr Roger Searle Professor Steve Robson et al.	Gestational changes in spiral artery vascular smooth muscle content using photoshop based image analysis	2005
Dr Gendie Lash Dr Harry Otun Dr Judith Bulmer Dr Roger Searle Professor Steve Robson et al.	Inhibition of extravillous trophoblast invasion by TGF-beta 1, 2 and 3 is associated with a reduction in secreted MMP-9 levels	2005
Dr Gendie Lash Dr Harry Otun Barbara Innes Dr Judith Bulmer Dr Roger Searle et al.	Inhibition of trophoblast cell invasion by TGFB1, 2, and 3 is associated with a decrease in active proteases	2005
Dr Yoshiharu Sakamoto Dr Judith Bulmer Dr Roger Searle Professor Steve Robson	Macrophages and not granulocytes are involved in cervical ripening	2005
Dr Roger Searle	The role of decidual leucocytes in reproductive success in humans and other species	2005
Dr Gendie Lash Dr Harry Otun Dr Judith Bulmer Dr Roger Searle Professor Steve Robson et al.	TNF-alpha and IFN-gamma inhibit extravillous trophoblast invasion in a paracrine manner via a mechanism independent of MMP-2 or MMP-9 levels.	2005
Paula Scaife Dr Roger Searle Professor Steve Robson Barbara Innes Dr Judith Bulmer et al.	Comparison of decidual leucocyte populations in spontaneous early pregnancy loss.	2004
Dr Gendie Lash Dr Harry Otun Barbara Innes Dr Roger Searle Dr Judith Bulmer et al.	Culture of placental villous explants in 8% oxygen does not alter their invasive phenotype	2004
Paula Scaife Dr Roger Searle Barbara Innes Professor Steve Robson Dr Judith Bulmer et al.	Cytokine production by CD8+ decidual leucocytes in early pregnancy	2004
Paula Scaife Dr Roger Searle Professor Steve Robson Barbara Innes Dr Judith Bulmer et al.	Cytokine production by CD8+decidual leucocytes in early pregnancy	2004
Dr Gendie Lash Dr Harry Otun Barbara Innes Dr Roger Searle Dr Judith Bulmer et al.	Inhibition of extravillous trophoblast cell invasion in 3% oxygen is due to an increase in PAI-2 production	2004
Dr Yoshiharu Sakamoto Dr Roger Searle Dr Judith Bulmer Professor Steve Robson	Interleukin-8 is involved in cervical dilatation but not in prelabour cervical ripening	2004
Dr Gendie Lash Dr Harry Otun Barbara Innes Dr Judith Bulmer Dr Roger Searle et al.	Invasion of extravillous trophoblast cells is inhibited in low oxygen conditions	2004
Dr Judith Bulmer Dr Roger Searle	No evidence for apoptosis of decidual leucocytes in normal and molar pregnancy: Implications for immune privilege	2004
Dr Roger Searle Dr Judith Bulmer	Placental Fas and Fas ligand expression in normal early, term and molar pregnancy	2004
Dr Harry Otun Dr Gendie Lash Barbara Innes Dr Judith Bulmer Dr Roger Searle et al.	Regulation of trophoblast invasion by TGF-beta: Role of apoptosis and proliferation.	2004
Paula Scaife Dr Roger Searle Professor Steve Robson Barbara Innes Dr Judith Bulmer et al.	[abstract] A comparison of cytotoxic decidual lymphocytes in early and late pregnancy	2003
Barbara Innes Dr Roger Searle Dr Judith Bulmer Professor Steve Robson	[abstract] Use of laser capture microdissection and RT-PCR to study gene expression in heterogeneous differentiating trophoblast populations	2003
Dr Harry Otun Dr Gendie Lash Dr Judith Bulmer Dr Roger Searle Professor Steve Robson et al.	Inhibition of first trimester human extravillous trophoblast invasion by TNF-alpha and IFN-gamma	2003
Dr Judith Bulmer Barbara Innes Dr Roger Searle Professor Steve Robson	M30 is expressed by extravillous trophoblast in the placental bed in the first half of normal human pregnancy	2003
Dr Harry Otun Dr Roger Searle Dr Judith Bulmer Professor Steve Robson	The effect of gestational age on trophoblast invasion	2003
Dr Harry Otun Dr Roger Searle Dr Judith Bulmer Professor Steve Robson	The effect of TGF beta inhibition on trophoblast invasion	2003
Dr Judith Bulmer Dr Roger Searle	Lack of apoptotic decidual leucocytes in hydatidiform mole: no evidence for Fas-Fas ligand system mediated maternal T cell tolerance in molar pregnancy	2002
Dr Roger Searle Dr Judith Bulmer	Expression of Fas/Fas ligand by decidual leukocytes in hydatidiform mole	2001
Dr Roger Searle Dr Judith Bulmer	Maternal immune tolerance during molar pregnancy: increased expression of Fas ligand on abnormal trophoblast induces apoptosis of activated decidual leucocytes	2001
Stephen Bromage Dr Roger Searle	Abnormal TGFβ levels in the amniotic fluid of Down syndrome pregnancies	2000
Dr Roger Searle Stephen Bromage	Human amniotic fluid lacks interleukin-2 and interleukin-15 but can interact with the β-chain of the interleukin-2 receptor	2000
Dr Roger Searle Dr Judith Bulmer	Decidual T lymphocyte activation in hydatidiform mole	1999
Dr Roger Searle Dr Judith Bulmer	Elevated expression of activation molecules by decidual lymphocytes in women suffering spontaneous early pregnancy loss	1999
Dr Roger Searle Dr Judith Bulmer	Immunoregulatory activity of decidua in spontaneous early pregnancy loss	1999
Dr Roger Searle Dr Judith Bulmer	Phenotypic analysis and proliferative responses of human endometrial granulated lymphocytes during the menstrual cycle	1999
Dr Roger Searle Dr Judith Bulmer	Up-regulation of natural killer cell cytotoxicity by interleukin-2: The effect of sex and parity	1999