Publications by Dr James Flint - ePrints

Browsing publications by Dr James Flint.

Newcastle Authors	Title	Year
Dr Fiona Cuskin Dr James Flint Carl Morland Dr Arnaud Basle Dr Alexandra Solovyova et al.	How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity	2012
Cedric Montanier Dr James Flint Dr Arnaud Basle Professor Rick Lewis Emeritus Professor Harry Gilbert et al.	A novel, noncatalytic carbohydrate-binding module displays specificity for galactose-containing polysaccharides through calcium-mediated oligomerization	2011
Dr Morten Nielsen Dr Louise Tailford Dr James Flint Dr Claire Dumon Emeritus Professor Harry Gilbert et al.	Substrate and Metal Ion Promiscuity in Mannosylglycerate Synthase	2011
Cedric Montanier Dr James Flint Dr David Bolam He Fang Xie Ziyuan Liu et al.	Circular Permutation Provides an Evolutionary Link between Two Families of Calcium-dependent Carbohydrate Binding Modules	2010
Cedric Montanier Dr Claire Dumon Dr James Flint Emeritus Professor Harry Gilbert	Signature Active Site Architectures Illuminate the Molecular Basis for Ligand Specificity in Family 35 Carbohydrate Binding Module	2010
Dr James Flint	Affinity maturation generates greatly improved xyloglucan-specific carbohydrate binding modules	2009
Dr Claire Dumon Dr James Flint Dr Susan Firbank Professor Rick Lewis Emeritus Professor Harry Gilbert et al.	Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function	2009
Cedric Montanier Dr James Flint Benedita Pinheiro Carl Morland Alan Cartmell et al.	The Active Site of a Carbohydrate Esterase Displays Divergent Catalytic and Noncatalytic Binding Functions	2009
Dr Catherine Meplan Dr James Flint Dr Franck Tourniaire Professor John Hesketh Professor Georg Lietz et al.	Two common single nucleotide polymorphisms in the gene encoding β-carotene 15,15′-monoxygenase alter β-carotene metabolism in female volunteers	2009
Dr Louise Tailford Dr James Flint Carl Morland Emeritus Professor Harry Gilbert	Understanding How Diverse beta-Mannanases Recognize Heterogeneous Substrates	2009
Dr Joseph Newman Professor Rick Lewis Emeritus Professor Harry Gilbert Dr James Flint	Crystal structure of a cellulosomal family 3 carbohydrate esterase from Clostridium thermocellum provides insights into the mechanism of substrate recognition	2008
Dr Claire Dumon Dr James Flint Professor Rick Lewis Professor Jeremy Lakey Carl Morland et al.	Engineering hyperthermostability into a GH₁₁ xylanase is mediated by subtle changes to protein structure	2008
Dr James Flint Dr David Bolam Emeritus Professor Harry Gilbert	Differential recognition of plant cell walls by microbial xylan-specific carbohydrate-binding modules	2006
He Fang Xie Dr James Flint Professor Jeremy Lakey Professor Rick Lewis Emeritus Professor Harry Gilbert et al.	Probing the Structural Basis for the Difference in Thermostability Displayed by Family 10 Xylanases	2006
Dr James Flint Dr David Bolam Emeritus Professor Harry Gilbert	Understanding the biological rationale for the diversity of cellulose-directed carbohydrate-binding modules in prokaryotic enzymes	2006
Dr James Flint Professor Rick Lewis Emeritus Professor Harry Gilbert Dr James Murray	A family 10 Thermoascus aurantiacus xylanase utilizes arabinose decorations of xylan as significant substrate specificity determinants	2005
Dr James Flint Dr David Bolam Dr Edward Taylor Emeritus Professor Harry Gilbert	Probing the mechanism of ligand recognition in family 29 carbohydrate-binding modules	2005
Dr James Flint Dr David Bolam Dr Louise Tailford Emeritus Professor Harry Gilbert	Structural dissection and high-throughput screening of mannosylglycerate synthase	2005
Dr James Flint Emeritus Professor Harry Gilbert Dr David Bolam	Ligand-mediated dimerization of a carbohydrate-binding module reveals a novel mechanism for protein-carbohydrate recognition	2004