Publications by Professor Faith Williams - ePrints

Browsing publications by Professor Faith Williams.

Newcastle Authors	Title	Year
Professor Faith Williams	New approaches build upon historical studies in dermal toxicology	2023
Abi Dalzell Professor Faith Williams Dr Colin Brown	Characterization of multidrug transporter-mediated efflux of avermectins in human and mouse neuroblastoma cell lines	2015
Professor Faith Williams Varshini Ravi Dr SarahJayne Boulton Dr Elaine Mutch Dr Christopher Jewell et al.	Factors influencing expression and specificity of carboxylesterases in skin: Implications for local and systemic paraben ester toxicity	2014
Dr Alison Forrester Martina Elias Emma Woodward Professor Faith Williams Professor Nick Reynolds et al.	Induction of a chloracne phenotype in an epidermal equivalent model by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is dependent on aryl hydrocarbon receptor activation and is not reproduced by aryl hydrocarbon receptor knock down	2014
Craig Moore Dr Simon Wilkinson Professor Peter Blain Dr Michael Dunn Dr Gillian Aust et al.	Percutaneous absorption and distribution of organophosphates (chlorpyrifos and dichlorvos) following dermal exposure and decontamination scenarios using in vitro human skin model	2014
Professor Faith Williams	Section editorial - Cutaneous biology	2014
Dr Simon Wilkinson Professor Peter Blain Professor Faith Williams	Use of a human skin in vitro model to investigate the influence of 'every-day' clothing and skin surface decontamination on the percutaneous penetration of organophosphates	2014
Dr Paul Jowsey Professor Faith Williams Professor Peter Blain	DNA damage responses in cells exposed to sulphur mustard	2012
Andrew Axon Dr Felicity May Dr Luke Gaughan Professor Faith Williams Professor Peter Blain et al.	Tartrazine and sunset yellow are xenoestrogens in a new screening assay to identify modulators of human oestrogen receptor transcriptional activity	2012
Dr Alison Forrester Professor Penny Lovat Professor Faith Williams Professor Nick Reynolds	Differential activation of the aryl hydrocarbon receptor and regulation of differentiation in the epidermal equivalent model	2011
Professor Faith Williams Dr Elaine Mutch	Heavy metal toxicity and implications for hepatobiliary diseases	2011
Dr Paul Jowsey Professor Faith Williams Professor Peter Blain	The role of homologous recombination in the cellular response to sulphur mustard	2011
Alison Forrester Professor Faith Williams Professor Nick Reynolds	Activation of the Aryl Hydrocarbon Receptor In Human Keratinocytes and Relevance To Chloracne	2010
Andy Axon Dr David Cowie Professor Fiona Oakley Professor Faith Williams Professor Peter Blain et al.	Acute oestradiol (E2) administration to mice results in liver portal tract inflammation	2010
Passapan Sriwichai Professor Faith Williams Dr Elaine Mutch	An investigation of the toxicity of silver nanoparticles to HL60 and Jurkat cells in vitro	2010
Ghazalla Benhusein Dr Elaine Mutch Professor Faith Williams	Genotoxic effect induced by hydrogen peroxide in human hepatoma cells using comet assay	2010
Ghazalla Benhusein Dr Elaine Mutch Professor Faith Williams	Genotoxic effect of inorganic arsenics in human hepatoma cells (HepG2 cells) using single cell gel electrophoresis	2010
Professor Faith Williams	The 2008 ICOH workshop on skin notation	2010
Dr Paul Jowsey Professor Faith Williams Professor Peter Blain	The role of homologous recombination in the cellular response to sulphur mustard	2010
Dr Katherine Betteley Dr Elaine Mutch Dr Colin Brown Professor Faith Williams	Characterisation of pesticide transport in neural cells	2009
Dr Kathryn Atherton Professor Faith Williams Professor Stephen Rushton Professor Peter Blain Dr Elaine Mutch et al.	DNA damage in horticultural farmers: a pilot study showing an association with organophosphate pesticide exposure	2009
Dr Paul Jowsey Professor Faith Williams Professor Peter Blain	DNA damage, signalling and repair after exposure of cells to the sulphur mustard analogue 2-chloroethyl ethyl sulphide	2009
Dr Katherine Betteley Professor Faith Williams Dr Elaine Mutch Dr Colin Brown	Characterisation of pesticide transport in SHSY-5Y neuroblastoma cells	2008
Dr Simon Wilkinson Professor Faith Williams	Cutaneous metabolism	2008
Dr Kathryn Atherton Professor Faith Williams Samantha Jameson Dr Elaine Mutch	DNA damage by single doses of five organophosphate pesticides to rats	2008
Dr Elaine Mutch Dr Kathryn Atherton Samantha Jameson Professor Faith Williams	DNA Damage In Horticultural Farmers With Chronic Exposure To Pesticide Mixtures, Including Organophosphate Pesticides	2008
Seth Remington Dr Paul Jowsey Professor Faith Williams Professor Peter Blain	Investigations into the genotoxic potential of dichlorvos	2008
Matthew Traynor Dr Simon Wilkinson Professor Faith Williams	Metabolism of butoxyethanol in excised human skin in vitro	2008
Professor Faith Williams	Potential for metabolism locally in the skin of dermally absorbed compounds	2008
Dr Elaine Mutch Professor Peter Blain Professor Faith Williams	A possible mechanism for the neurotoxicity of trichloroethylene to man	2007
Dr Simon Wilkinson Professor Faith Williams	Analysis, interpretation, and extrapolation of dermal permeation data using diffusion-based mathematical models	2007
Matthew Traynor Dr Simon Wilkinson Professor Faith Williams	Corrigendum to "The influence of water mixtures on the dermal absorption of glycol ethers" [Toxicol. Appl. Pharmacol. 218 (2007) 128-134] (DOI:10.1016/j.taap.2006.09.019)	2007
Dr Simon Wilkinson Professor Faith Williams	Cutaneous metabolism	2007
Dr Elaine Mutch Professor Faith Williams	Effect of arsenic on DNA damage, glutathione content, apoptosis and necrosis in HaCat cells	2007
Dr Christopher Jewell Professor Faith Williams	Hydrolysis of a series of parabens by skin microsomes and cytosol from human and minipigs and in whole skin in short-term culture	2007
Dr Gillian Aust Dr Simon Wilkinson Dr Michael Dunn Professor Faith Williams	Influence of formulation on the dermal absorption of pesticide actives at spray dilution concentrations	2007
Dr Christopher Jewell Phillippa Bennett Dr Elaine Mutch Professor Faith Williams	Inter-individual variability in esterases in human liver	2007
Dr Christopher Jewell Professor Faith Williams	Specificity of procaine and ester hydrolysis by human, minipig, and rat skin and liver	2007
Dr Christopher Jewell Professor Faith Williams	The distribution of esterases in the skin of the minipig	2007
Ria Wilkinson Dr Christopher Jewell Dr Simon Wilkinson Professor Faith Williams Professor Peter Blain et al.	The effect of in vitro receptor media choice on the percutaneous absorption of methyl paraben	2007
Matthew Traynor Dr Simon Wilkinson Professor Faith Williams	The influence of water mixtures on the dermal absorption of glycol ethers	2007
Matthew Traynor Dr Simon Wilkinson Professor Faith Williams	The influence of water mixtures on the dermal absorption of glycol ethers (vol 218, pg 128, 2007)	2007
Dr Elaine Mutch Professor Ann Daly Professor Faith Williams	The Relationship between PON1 Phenotype and PON1-192 Genotype in Detoxification of Three Oxons by Human Liver	2007
Dr Elaine Mutch Professor Faith Williams	The role of esterases in the metabolism of ciclesonide to desisobutyryl-ciclesonide in human tissue	2007
Zhen Jiang Dr Elaine Mutch Professor Peter Blain Professor Faith Williams	Conversion of trichloroethylene to chloral using occupationally relevant levels	2006
Professor Faith Williams	Dermal absorption of caffeine and testosterone through SLS-treated human skin in vitro	2006
Dr Elaine Mutch Professor Faith Williams	Diazinon, chlorpyrifos and parathion are metabolised by multiple cytochromes P450 in human liver	2006
Dr Kathryn Atherton Professor Faith Williams Samantha Jameson Dr Elaine Mutch	DNA damage by dichlorvos and repair profiles in human lymphocytes, in vitro	2006
Professor Faith Williams Dr Kathryn Atherton Sheila Jamieson Dr Elaine Mutch	DNA damage by organophosphate pesticides and repair profiles in human lymphocytes, in vitro	2006
Dr Christopher Jewell Professor Faith Williams	Hydrolysis of esters by human, mini-pig, and rat skin microsomes and cytosol	2006
Professor Faith Williams	In vitro studies - How good are they at replacing in vivo studies for measurement of skin absorption?	2006
Dr Simon Wilkinson Professor Laura Greaves Professor Faith Williams	Interactions of skin thickness and physicochemical properties of test compounds in percutaneous penetration studies	2006
Dr Ovnair Sepai Adem BEM Professor Faith Williams David Henderson Professor Peter Blain	Biological monitoring of exposure to organochlorine pesticides in an African population	2005
Professor Faith Williams	Cutaneous metabolism of glycol ethers	2005
Dr Simon Wilkinson Professor Faith Williams	Inter- and intralaboratory variation of in vitro diffusion cell measurements: An international multicenter study using quasi-standardized methods and materials	2005
Professor Faith Williams	The effect of sodium lauryl sulphate upon the distribution of testosterone through human skin in vitro	2005
Dr Elaine Mutch Samantha Jameson Professor Faith Williams	The influence of chemical structure on the toxicity of organophosphate pesticides	2005
Dr Simon Wilkinson Professor Faith Williams	The relationship between in vivo dermal penetration studies in humans and in vitro predictions using human skin	2005
Vanessa Gage Professor Peter Blain Julian Leathart Professor Ann Daly Professor Faith Williams et al.	Association of DNA damage to human peripheral lymphocytes with age and MnSOD and OGG1 genotype	2004
Dr Simon Wilkinson Clair Roper Professor Faith Williams	CEFIC Workshop on methods to determine permeation for human risk assessment	2004
Vanessa Gage Professor Peter Blain Dr Elaine Mutch Professor Faith Williams	DNA damage and 8-hydroxy-2 '-deoxyguanosine formation due to hydrogen peroxide exposure in HepG2 cells	2004
Dr Elaine Mutch Professor Faith Williams	Do multiple P450 isoforms contribute to parathion, diazinon and chlorpyrifos metabolism in man?	2004
Professor Faith Williams	EDETOX. Evaluations and predictions of dermal absorption of toxic chemicals	2004
Matthew Traynor Dr Simon Wilkinson Professor Faith Williams	Effects of water on the absorption of two glycol ethers through human skin in vitro	2004
Professor Faith Williams	Evaluations and predictions of dermal absorption of toxic chemicals	2004
Dr Simon Wilkinson Professor Faith Williams	In vitro predictions of skin absorption of caffeine, testosterone, and benzoic acid: A multi-centre comparison study	2004
Dr Elaine Mutch Dr Lindsey Ferrie Christopher Pedder Professor Faith Williams	Measurement of DNA damage from organophosphate pesticides	2004
Professor Faith Williams	Percutaneous penetration and metabolism of 2-butoxyethanol	2004
Dr Simon Wilkinson Professor Faith Williams	Percutaneous penetration of malathion and parathion: Dose and vehicle effects	2004
Dr Simon Wilkinson Professor Faith Williams	Percutaneous penetration of parathion in ethanol and xylene vehicles	2004
Emma Davis Vanessa Gage Professor Ann Daly Professor Faith Williams	The contribution of genotype to DNA damage in lymphocytes from healthy volunteers	2004
James Wakefield Professor Faith Williams	The percutaneous penetration of testosterone and water using an in vitro model of skin irritation	2004
Dr Barry King Julian Leathart Dr Elaine Mutch Professor Faith Williams Professor Ann Daly et al.	CYP3A5 phenotype-genotype correlations in a British population	2003
Dr Elaine Mutch Professor Ann Daly Julian Leathart Professor Peter Blain Professor Faith Williams et al.	Do multiple cytochrome P450 isoforms contribute to parathion metabolism in man?	2003
Dr Elaine Mutch Dr Lindsey Ferrie Christopher Pedder Professor Faith Williams Professor Ann Daly et al.	The role of metabolism in determining the genotoxicity of organophosphate pesticides	2003
Dr Namrata Bahadur Julian Leathart Dr Elaine Mutch Dr Stuart Dunn Professor Faith Williams et al.	CYP2C8 polymorphisms in Caucasians and their relationship with paclitaxel 6α-hydroxylase activity in human liver microsomes	2002
Dr Simon Wilkinson Professor Faith Williams	Effects of experimental conditions on absorption of glycol ethers through human skin in vitro	2002
Dr Simon Wilkinson Professor Faith Williams	Effects of experimental conditions on absorption of glycol ethers through human skin in vitro	2002
Professor Laura Greaves Dr Simon Wilkinson Professor Faith Williams	Factors affecting percutaneous absorption of caffeine in vitro	2002
Fei Lee Professor Faith Williams	Influence of the skin reservoir on absorption of testosterone through rat skin in vitro and in vivo	2002
Professor Faith Williams	Percutaneous penetration and metabolism of 2-ethoxyethanol	2002
Dr Simon Wilkinson Professor Faith Williams	Dermal absorption of pyridine and some methyl pyridines in vitro	2001
Abdullah Saati Dr Gail de Blaquiere Dr Elaine Mutch Professor Faith Williams	Effects of multiple doses of diazinon on blood and brain esterases in the mouse	2001
Dr Simon Wilkinson Professor Faith Williams	In vitro dermal absorption of liquids	2001
Fei Lee Professor Faith Williams	Interindividual variability in the percutaneous penetration of testosterone through human skin in vitro	2001
Professor Faith Williams Dr John Edwards	Peripheral cholinesterase inhibition by occupational chlorpyrifos exposure in Australian termiticide applicators	2001
Emma Davis Professor Ann Daly Professor Faith Williams	Quantitation of in vitro DNA damage using the comet assay	2001
Dr Elaine Mutch Professor Faith Williams Professor Peter Blain	Cytogenetic response without changes in peripheral cholinesterase enzymes following exposure to a sheep dip containing diazinon in vivo and in vitro	2000
Dr Gail de Blaquiere Louise Waters Professor Peter Blain Professor Faith Williams	Electrophysiological and biochemical effects of single and multiple doses of the organophosphate diazinon in the mouse	2000
Dr Christopher Jewell Professor Faith Williams	Percutaneous absorption and metabolism of dinitrochlorobenzene in vitro	2000
Dr Christopher Jewell Professor Faith Williams	Percutaneous absorption and metabolism of dinitrochlorobenzene in vitro	2000
Professor Faith Williams	Percutaneous penetration and dermal metabolism of triclosan (2,4,4'- trichloro-2'-hydroxydiphenyl ether)	2000
Professor Faith Williams	Percutaneous penetration studies for risk assessment	2000
Dr Elaine Mutch Professor Peter Blain Professor Faith Williams	The role of metabolism in determining susceptibility to parathion toxicity in man	1999
Professor Peter Blain Professor Faith Williams	The percutaneous absorption and skin distribution of lindane in man. II. In vitro studies	1997
Professor Peter Blain Professor Faith Williams	The effect of sulphur mustard on glutathione levels in rat lung slices and the influence of treatment with arylthiols and cysteine esters	1996
Dr Elaine Mutch Professor Peter Blain Professor Faith Williams	Interindividual variations in enzymes controlling organophosphate toxicity in man	1992