Publications by Dr Colin Brown - ePrints

Browsing publications by Dr Colin Brown.

Newcastle Authors	Title	Year
Elena Tasinato Dr Kathryn Garner Dr Colin Brown	Development of a Highly Differentiated Human Primary Proximal Tubule MPS Model (aProximate MPS Flow)	2024
Dr Jack Leslie Dr Marina Garcia Macia Dr Saimir Luli Dr Julie Worrell William Reilly et al.	c-Rel orchestrates energy-dependant epithelial and macrophage reprogramming in fibrosis	2020
Dr Git Chung Dr Colin Brown	Derivation of a system-independent Ki for Pgp-mediated digoxin transport from system-dependent IC₅₀ data by accounting for the contribution of additional digoxin transporters	2018
Sal Bakar Dr Peter Avery Dr Colin Brown Professor Ann Daly Professor Farhad Kamali et al.	Genetic and Clinical Factors Are Associated With Statin-Related Myotoxicity of Moderate Severity: A Case–Control Study	2018
Sarah Billington Dr Colin Brown	Microsomal and Cytosolic Scaling Factors in Dog and Human Kidney Cortex and Application for In Vitro-In Vivo Extrapolation of Renal Metabolic Clearance	2018
Sarah Billington Dr Colin Brown	The importance of incorporating OCT2 plasma membrane expression and membrane potential in ivive of metformin renal secretory clearance S	2018
Sarah Billington Git Chung Dr Colin Brown	Abundance of Drug Transporters in the Human Kidney Cortex as Quantified by Quantitative Targeted Proteomics	2016
Git Chung Sarah Billington Dr Sarah Jenkinson Dr Colin Brown	Drug transporters in the kidney	2016
Sal Bakar Professor Farhad Kamali Dr Colin Brown	Effect of Statins on Functional Expression of Membrane Transporters in L6 Rat Skeletal Muscle Cells	2016
Abi Dalzell Professor Faith Williams Dr Colin Brown	Characterization of multidrug transporter-mediated efflux of avermectins in human and mouse neuroblastoma cell lines	2015
Dr Phillip Probert Git Chung Dr Simon Cockell Professor Loranne Agius Steven White et al.	Utility of B-13 Progenitor-Derived Hepatocytes in Hepatotoxicity and Genotoxicity Studies	2014
Christopher Hill Dr David Jamieson Huw Thomas Dr Colin Brown Professor Alan Boddy et al.	Characterisation of the roles of ABCB1, ABCC1, ABCC2 and ABCG2 in the transport and pharmacokinetics of actinomycin D in vitro and in vivo	2013
Professor Rakesh Heer Dr Anastasia Hepburn Dr Stuart Williamson Dr Amy Kennedy Dr Amira El-Sherif et al.	Renal differentiation from adult spermatogonial stem cells	2013
Dr Sarah Jenkinson Dr Colin Brown	Drug transporter expression and function in primary cultures of human renal epithelial cells	2012
Anastasia Rigas Dr Stuart Williamson Dr Amy Kennedy Dr Amira El-Sherif Professor Naeem Soomro et al.	Renal differentiation from adult spermatogonial stem cells	2012
Dr Sarah Jenkinson Git Chung Ellen Van Loon Sal Bakar Abi Dalzell et al.	The limitations of renal epithelial cell line HK-2 as a model of drug transporter expression and function in the proximal tubule	2012
Dr Sarah Jenkinson Ellen Van Loon Abi Dalzell Dr Colin Brown	Does the HK2 cell line represent a suitable model for the study of drug transporter expression by renal epithelial cells?	2011
Dr Katherine Betteley Dr Elaine Mutch Dr Colin Brown Professor Faith Williams	Characterisation of pesticide transport in neural cells	2009
Dr Colin Brown Dr Rachel Sayer	Characterisation of human tubular cell monolayers as a model of proximal tubular xenobiotic handling	2008
Dr Katherine Betteley Professor Faith Williams Dr Elaine Mutch Dr Colin Brown	Characterisation of pesticide transport in SHSY-5Y neuroblastoma cells	2008
Dr Rachel Sayer Dr Colin Brown	Human Proximal Tubular Epithelium Actively Secretes but Does Not Retain Rosuvastatin	2008
Dr Amy Kennedy Dr Colin Brown	The contribution of Organic Anion Transporters OAT1 and OAT3 to the renal uptake of rosuvastatin	2007
Amy Windass Dr Simon Lowes Dr Colin Brown	The Contribution of Organic Anion Transporters OAT1 and OAT3 to the Renal Uptake of Rosuvastatin	2007
Dr Rachel Sayer Dr Colin Brown	Characterisation of creatinine secretion across monolayers of mouse proximal tubule cells	2006
Abdul-Haq Ansari Dr Colin Brown	Characterisation of transporter expression in primary aortic endothelial and EA.hy926 cell cell lines	2006
Dr Colin Brown Dr Penney Gray Amy Windass	Functional impact of SNPs in OATP1B1 on rosuvastatin uptake in Xenopus oocytes	2005
Dr Colin Brown Dr Penney Gray Amy Windass	Functional impact upon rosuvastatin uptake of single nucleotide polymorphisms of OATP family members expressed in Xenopus oocytes	2005
Dr Colin Brown Dr Amy Kennedy	Rosuvastatin pharmacokinetics in heart transplant recipients administered an antirejection regimen including cyclosporine	2004
Dr Colin Brown Dr Amy Kennedy	The effect of gemfibrozil on the pharmacokinetics of rosuvastatin	2004
Dr Colin Brown Seema Chauhan	Functional characterisation of endogenous organic cation transporters expressed by Hela cells	2003
Dr Colin Brown Seema Chauhan	Na+ dependent MPP+ uptake across the apical membrane of Caco-2 cells is not mediated by hOCTN2 [abstract]	2002
Seema Chauhan Dr Colin Brown	Differential expression of hOCT1, hOCT2 and hOCTN2 along the human gastrointestinal tract	2001
Dr Michael Gray Dr Colin Brown Professor Nicholas Simmons	Bradykinin regulation of salt transport across mouse inner medullary collecting duct epithelium involves activation of a Ca2+ -dependent Cl- conductance	2000
Kelly Bleasby Dr Colin Brown	Characterization of MPP+ secretion across human intestinal Caco-2 cell monolayers: Role of P-glycoprotein and a novel Na+-dependent organic cation transport mechanism	2000
Kelly Bleasby Dr Colin Brown	The organic cation transporter OCT2 mediates the uptake of β-adrenoceptor antagonists across the apical membrane of renal LLC-PK1 cell monolayers	2000
Professor David Thwaites Dr Colin Brown Emeritus Professor Barry Hirst Professor Nicholas Simmons	L-Alanine absorption in human intestinal cells driven by the proton electrochemical gradient	1994
Professor David Thwaites Dr Colin Brown Emeritus Professor Barry Hirst Professor Nicholas Simmons	H⁺-coupled dipeptide (glycylsarcosine) transport across apical and basal borders of human intestinal Caco-2 cell monolayers display distinctive characteristics	1993
Professor David Thwaites Dr Colin Brown Emeritus Professor Barry Hirst Professor Nicholas Simmons	Na⁺-independent, H⁺-coupled transepithelial beta-alanine absorption by human intestinal Caco-2 cell monolayers	1993
Professor David Thwaites Dr Colin Brown Emeritus Professor Barry Hirst Professor Nicholas Simmons	Transepithelial glycylsarcosine transport in intestinal Caco-2 cells mediated by expression of H⁺-coupled carriers at both apical and basal membranes	1993