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Browsing publications by Professor Robert Hirt.

Newcastle AuthorsTitleYearFull text
Dr Marco Salamina
Dr Johan Panek
Karla Helena Bueno
Charlotte Brown
Professor Robert Hirt
et al.
Adaptation to genome decay in the structure of the smallest eukaryotic ribosome2022
Dr Valentina Margarita
Nick Bailey
Professor Robert Hirt
Effect of the Symbiosis with Mycoplasma hominis and Candidatus Mycoplasma girerdii on Trichomonas vaginalis Metronidazole Susceptibility2022
Dr Valentina Margarita
Nick Bailey
Professor Robert Hirt
Two different species of Mycoplasma endosymbionts can influence Trichomonas vaginalis pathophysiology2022
Tamara Salloum Salloum
Professor Robert Hirt
Advances in Understanding Leishmania Pathobiology: What does RNA-Seq Tell Us?2021
Nick Bailey
Professor Robert Hirt
Sporadic isolation of Tetratrichomonas species from the cattle urogenital tract2021
Heli Monttinen
Dr Cedric Bicep
Dr Timothy Williams
Professor Robert Hirt
The genomes of nucleocytoplasmic large DNA viruses: viral evolution writ large2021
Will Lewis
Kacper Sendra
Professor Robert Hirt
Professor T. Martin Embley FMedSci FRS
Convergent evolution of hydrogenosomes from mitochondria by gene transfer and loss2020
Tamara Salloum Salloum
Professor Robert Hirt
Expanded genome-wide comparisons give novel insights into population structure and genetic heterogeneity of Leishmania tropica complex2020
Dr Peter Major
Kacper Sendra
Dr Paul Dean
Dr Tom Williams
Andrew Watson
et al.
A new family of cell surface located purine transporters in Microsporidia and related fungal endoparasites2019
Dr Ewen Sommerville
Professor Robert Hirt
Characterization of the BspA and Pmp protein family of trichomonads2019
Professor Robert Hirt
Mucosal microbial parasites/symbionts in health and disease: an integrative overview2019
Dr Jacob Biboy
Professor Waldemar Vollmer
Professor Robert Hirt
The Protozoan Trichomonas vaginalis Targets Bacteria with Laterally Acquired NlpC/P60 Peptidoglycan Hydrolases2018
Dr Paul Dean
Kacper Sendra
Dr Tom Williams
Andrew Watson
Dr Peter Major
et al.
Transporter gene acquisition and innovation in the evolution of Microsporidia intracellular parasites2018
Dr Alina Goldberg Cavalleri
Dr Paul Dean
Dr Tom Williams
Dr Sirintra Nakjang
Dr Shaojun Long
et al.
Evolutionary conservation and in vitro reconstitution of microsporidian iron–sulfur cluster biosynthesis2017
Dr Tom Williams
Dr Sirintra Nakjang
Professor Robert Hirt
Professor T. Martin Embley FMedSci FRS
A Recent Whole-Genome Duplication Divides Populations of a Globally Distributed Microsporidian2016
Dr Paul Dean
Professor Robert Hirt
Professor T. Martin Embley FMedSci FRS
Microsporidia: why make nucleotides if you can steal them?2016
Dr Valentina Margarita
Professor Robert Hirt
Symbiotic Association with Mycoplasma hominis Can Influence Growth Rate, ATP Production, Cytolysis and Inflammatory Response of Trichomonas vaginalis2016
Professor Robert Hirt
Dr Cecilia Alsmark
Professor T. Martin Embley FMedSci FRS
Lateral gene transfers and the origins of the eukaryote proteome: a view from microbial parasites2015
Andrew Watson
Dr Tom Williams
Professor Robert Hirt
Professor T. Martin Embley FMedSci FRS
Transcriptomic profiling of host-parasite interactions in the microsporidian Trachipleistophora hominis2015
Professor Robert Hirt
Trichomonas vaginalis origins, molecular pathobiology and clinical considerations2015
Dr Eva Heinz
Dr Paul Dean
Dr Alina Goldberg Cavalleri
Dr Sirintra Nakjang
Dr Alison Gregory
et al.
Plasma Membrane-Located Purine Nucleotide Transport Proteins are Key Components for Host Exploitation by Microsporidian Intracellular Parasites2014
Dr Paul Dean
Dr Peter Major
Dr Sirintra Nakjang
Professor Robert Hirt
Professor T. Martin Embley FMedSci FRS
et al.
Transport proteins of parasitic protists and their role in nutrient salvage2014
Professor Robert Hirt
What is the importance of zoonotic trichomonads for human health?2014
Professor Robert Hirt
Trichomonas vaginalis virulence factors: an integrative overview2013
Dr Cecilia Alsmark
Dr Sirintra Nakjang
Professor T. Martin Embley FMedSci FRS
Professor Robert Hirt
Patterns of prokaryotic lateral gene transfers affecting parasitic microbial eukaryotes2013
Dr Sirintra Nakjang
Dr Tom Williams
Dr Eva Heinz
Andrew Watson
Dr Peter Foster
et al.
Reduction and Expansion in Microsporidian Genome Evolution: New Insights from Comparative Genomics2013
Dr Sirintra Nakjang
Dr Didier Ndeh
Professor Anil Wipat
Dr David Bolam
Professor Robert Hirt
et al.
A Novel Extracellular Metallopeptidase Domain Shared by Animal Host-Associated Mutualistic and Pathogenic Microbes2012
Matt Collison
Professor Robert Hirt
Professor Anil Wipat
Dr Sirintra Nakjang
Data mining the human gut microbiota for therapeutic targets2012
Dr Keith Flanagan
Dr Sirintra Nakjang
Dr Jennifer Hallinan
Professor Colin Harwood
Professor Robert Hirt
et al.
Microbase2.0: a generic framework for computationally intensive bioinformatics workflows in the cloud2012
Dr Eva Heinz
Dr Tom Williams
Dr Sirintra Nakjang
Dr Christophe Noel
Dr Daniel Swan
et al.
The Genome of the Obligate Intracellular ParasiteTrachipleistophora hominis: New Insights into Microsporidian Genome Dynamics and Reductive Evolution2012
Professor Robert Hirt
Dr Sirintra Nakjang
Trichomonas vaginalis Pathobiology: New Insights from the Genome Sequence2011
Dr Sirintra Nakjang
Professor Robert Hirt
Professor Anil Wipat
Automatic extraction of microorganisms and their habitats from free text using text mining workflows2011
Professor Robert Hirt
Trichomonas vaginalis genome2010
Dr Christophe Noel
Professor Robert Hirt
Trichomonas vaginalis vast BspA-like gene family: evidence for functional diversity from structural organisation and transcriptomics2010
Professor Robert Hirt
A metazoan/plant-like capping enzyme and cap modified nucleotides in the unicellular eukaryote Trichomonas vaginalis2010
Dr Karin Hjort
Dr Alina Goldberg Cavalleri
Anastasios Tsaousis
Professor Robert Hirt
Professor T. Martin Embley FMedSci FRS
et al.
Diversity and reductive evolution of mitochondria among microbial eukaryotes2010
Dr Cecilia Alsmark
Professor Robert Hirt
Professor T. Martin Embley FMedSci FRS
Horizontal gene transfer in eukaryotic parasites: a case study of Entamoeba histolytica and Trichomonas vaginalis2009
Anastasios Tsaousis
Dr Alina Goldberg Cavalleri
Professor Robert Hirt
Professor T. Martin Embley FMedSci FRS
A novel route for ATP acquisition by the remnant mitochondria of Encephalitozoon cuniculi2008
Dr Alina Goldberg Cavalleri
Anastasios Tsaousis
Professor Robert Hirt
Professor T. Martin Embley FMedSci FRS
Localization and functionality of microsporidian iron-sulphur cluster assembly proteins2008
Dr Simon Harris
Professor Robert Hirt
Professor T. Martin Embley FMedSci FRS
Reductive Evolution of the Mitochondrial Processing Peptidases of the Unicellular Parasites Trichomonas vaginalis and Giardia intestinalis2008
Christopher Cox
Professor Robert Hirt
Dr Simon Harris
Professor T. Martin Embley FMedSci FRS
The archaebacterial origin of eukaryotes2008
Professor Robert Hirt
Dr Christophe Noel
Trichomonas vaginalis surface proteins: a view from the genome2007
Professor Robert Hirt
A genomic survey of the fish parasite Spironucleus salmonicida indicates genomic plasticity among diplomonads and significant lateral gene transfer in eukaryote genome evolution2007
Professor Robert Hirt
Professor T. Martin Embley FMedSci FRS
Golgi-associated genes in the oxymonad Monocercomonoides sp suggest the presence of a cryptic organelle.2007
Professor Robert Hirt
Professor T. Martin Embley FMedSci FRS
Of clades and clans: terms for phylogenetic relationships in unrooted trees2007
Dr Christophe Noel
Professor Robert Hirt
Professor T. Martin Embley FMedSci FRS
Structure and Content of the Entamoeba histolytica Genome2007
Dr Christophe Noel
Professor Robert Hirt
Dramatic reorganisation of Trichomonas endomembranes during amoebal transformation: A possible role for G-proteins2006
Professor Robert Hirt
Evolution of four gene families with patchy phylogenetic distributions: Influx of genes into protist genomes2006
Professor Robert Hirt
Identification of a very large Rab GTPase family in the parasitic protozoan Trichomonas vaginalis2005
Dr Cecilia Alsmark
Professor Robert Hirt
Professor T. Martin Embley FMedSci FRS
The genome of the protist parasite Entamoeba histolytica2005
Professor Robert Hirt
Professor T. Martin Embley FMedSci FRS
Trichomonas hydrogenosomes contain the NADH dehydrogenase module of mitochondrial complex I2004
Professor Robert Hirt
An overview on eukaryote origins and evolution: the beauty of the cell and the fabulous gene phylogenies2004
Professor Robert Hirt
Organelles, Genomes and Eukaryote Phylogeny: An Evolutionary Synthesis in the Age of Genomics2004
Professor Robert Hirt
RACE and RAGE cloning in parasitic microbial eukaryotes2004
Professor Robert Hirt
Professor T. Martin Embley FMedSci FRS
Dr Scott Muller
The amitochondriate eukaryote Trichomonas vaginalis contains a divergent thioredoxin-linked peroxiredoxin antioxidant system2004
Professor Robert Hirt
Professor T. Martin Embley FMedSci FRS
Biochemical and genetic evidence for a family of heterotrimeric G-proteins in Trichomonas vaginalis2003
Professor Robert Hirt
Professor T. Martin Embley FMedSci FRS
Horizontal gene transfer and the evolution of parasitic protozoa2003
Professor Robert Hirt
Molecular evolution of the vertebrate blood coagulation network2003
Professor Robert Hirt
Professor T. Martin Embley FMedSci FRS
A mitochondrial remnant in the microsporidian Trachipleistophora hominis2002
Professor Robert Hirt
Professor T. Martin Embley FMedSci FRS
A novel potential surface protein in Trichomonas vaginalis contains a leucine-rich repeat shared by micro-organisms from all three domains of life2002
Professor Robert Hirt
Professor T. Martin Embley FMedSci FRS
A novel potential surface protein in Trichomonas vaginalis contains a leucine-rich repeat shared by micro-organisms from all three domains of life2002
Professor Robert Hirt
Professor T. Martin Embley FMedSci FRS
The diversity and evolution of thioredoxin reductase: new perspectives2002
Professor Robert Hirt
Dr Katalin Kovacs
Professor T. Martin Embley FMedSci FRS
The ribulose-1,5-bisphosphate carboxylase/oxygenase gene cluster of Methylococcus capsulatus (Bath)2002
Professor Robert Hirt
Liddle's syndrome: a novel mouse Nedd4 isoform regulates the activity of the epithelial Na+ channel2001
Professor Robert Hirt
Professor T. Martin Embley FMedSci FRS
A single eubacterial origin of eukaryotic pyruvate: ferredoxin oxidoreductase genes: implications for the evolution of anaerobic eukaryotes1999
Professor Robert Hirt
Professor T. Martin Embley FMedSci FRS
Microsporidia are related to Fungi: evidence from the largest subunit of RNA polymerase II and other proteins1999
Professor Robert Hirt
Professor T. Martin Embley FMedSci FRS
Microsporidia are related to Fungi: Evidence from the largest subunit of RNA polymerase II and other proteins1999
Professor T. Martin Embley FMedSci FRS
Professor Robert Hirt
Early branching eukaryotes?1998
Professor Robert Hirt
Professor T. Martin Embley FMedSci FRS
Molecular and cellular evolution of ciliates: a phylogenetic perspective1998
Professor Robert Hirt
Professor T. Martin Embley FMedSci FRS
Molecular phylogeny of Trichomonads and Naegleria: implication for the relative timing of the mitochondrion endosymbiosis1998
Professor Robert Hirt
Professor T. Martin Embley FMedSci FRS
A mitochondrial Hsp70 orthologue in Vairimorpha necatrix: molecular evidence that microsporidia once contained mitochondria1997
Professor Robert Hirt
Professor T. Martin Embley FMedSci FRS
A mitochondrial-like targeting signal on the hydrogenosomal malic enzyme from the anaerobic fungus Neocallimastix frontalis: support for the hypothesis that hydrogenosomes are modified mitochondria1997
Professor Robert Hirt
Assessment of cell polarity1996
Professor Robert Hirt
Professor T. Martin Embley FMedSci FRS
Molecular data suggest an early acquisition of the mitochondrion endosymbiont1996
Professor T. Martin Embley FMedSci FRS
Professor Robert Hirt
Multiple origins of anaerobic ciliates with hydrogenosomes within the radiation of aerobic ciliates1995
Professor Robert Hirt
Professor T. Martin Embley FMedSci FRS
Phylogenetic relationships among karyorelictids and heterotrichs inferred from small subunit rRNA sequences: resolution at the base of the ciliate tree1995
Professor Robert Hirt
The polymeric immunoglobulin receptor: signals for polarized expression1995
Professor T. Martin Embley FMedSci FRS
Professor Robert Hirt
Biodiversity at the molecular level: the domains, kingdoms and phyla of life1994
Professor Robert Hirt
Inducible protein expression using a glucocorticoid-sensitive vector1994
Professor T. Martin Embley FMedSci FRS
Professor Robert Hirt
Some rumen ciliates have endosymbiotic methanogens1994
Professor Robert Hirt
Transcytosis of the polymeric Ig receptor requires phosphorylation of serine 664 in the absence but not the presence of dimeric IgA1993
Professor Robert Hirt
Highly inducible synthesis of heterologous proteins in epithelial cells carrying a glucocorticoid-responsive vector1992
Professor Robert Hirt
Role of transepithelial transport in triggering a mucosal immune response and in delivery of mucosal antibodies into secretions1992
Professor Robert Hirt
Production and use of monoclonal IgA antibodies complexed with recombinant secretory component for passive mucosal protection1991