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Browsing publications by Dr Viktor Korolchuk.

Newcastle AuthorsTitleYearFull text
Dr Maria Georgiou
Dr Chunbo Yang
Rob Atkinson
Dr Adriana Buskin
Dr Joseph Collin
et al.
Activation of autophagy reverses progressive and deleterious protein aggregation in PRPF31 patient iPSC-derived retinal pigment epithelium cells2022
Chanachai Sae-Lee
Dr Timothy Barrow
Dr Yoana Rabanal Ruiz
Daniel Green
Dr Viktor Korolchuk
et al.
Genomic targets and selective inhibition of DNA methyltransferase isoforms2022
Dr Jack Leslie
Hannah Paish
Amy Collins
Rebecca Scott
Abi Watson
et al.
A Mammalian Target of Rapamycin-Perilipin 3 (mTORC1-Plin3) Pathway is essential to Activate Lipophagy and Protects Against Hepatosteatosis2021
Marti Cadena Sandoval
Dr Bernadette Carroll
Dr Viktor Korolchuk
G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling2021
Dr Tengfei Wan
Mary Johnson
Dr Viktor Korolchuk
Dr Gabriele Saretzki
Increased telomerase improves motor function and alpha-synuclein pathology in a transgenic mouse model of Parkinson’s disease associated with enhanced autophagy2021
Dr Daniel Erskine
Dr David Koss
Dr Viktor Korolchuk
Professor Tiago Outeiro
Professor Johannes Attems
et al.
Lipids, lysosomes and mitochondria: insights into Lewy body formation from rare monogenic disorders2021
Dr Yoana Rabanal Ruiz
Lucy Sedlackova
Dr Glyn Nelson
Dr Bernadette Carroll
Dr Viktor Korolchuk
et al.
mTORC1 activity is supported by spatial association with focal adhesions2021
Dr Viktor Korolchuk
Ochratoxin A induces NLRP3 inflammasome-mediated pyroptosis via activation of ROS modulated by autophagy in vitro2021
Dr Viktor Korolchuk
Autophagy in Neurodegenerative Diseases2020
Edvinas Cerniauskas
Dr Marzena Kurzawa-Akanbi
Dr Long Xie
Dr Dean Hallam
Marina Moya Molina
et al.
Complement modulation reverses pathology in Y402H-retinal pigment epithelium cell model of AMD by restoring lysosomal function2020
Dr Viktor Korolchuk
Redox signalling in physiology, ageing and disease2020
Lucy Sedlackova
Dr Viktor Korolchuk
The crosstalk of NAD, ROS and autophagy in cellular health and ageing2020
Lucy Sedlackova
George Kelly
Dr Viktor Korolchuk
The pROS of Autophagy in Neuronal Health2020
Lucy Sedlackova
Dr Viktor Korolchuk
Mitochondrial quality control as a key determinant of cell survival2019
Dr Viktor Korolchuk
Dr Bernadette Carroll
PCV2 replication promoted by oxidative stress is dependent on the regulation of autophagy on apoptosis2019
Dr Viktor Korolchuk
Preface2019
Clara Correia Melo
Dr Jodie Birch
Edward Fielder
Dr James Chapman
Dr Anthony Lagnado
et al.
Rapamycin improves healthspan but not inflammaging in nfkb1-/- mice2019
Dr Olena Kucheryavenko
Dr Glyn Nelson
Professor Thomas von Zglinicki
Dr Viktor Korolchuk
Dr Bernadette Carroll
et al.
The mTORC1-autophagy pathway is a target for senescent cell elimination2019
Dr Viktor Korolchuk
Autophagy: 'Self-Eating' Your Way to Longevity2018
Dr Yoana Rabanal Ruiz
Dr Viktor Korolchuk
mTORC1 and nutrient homeostasis: The central role of the lysosome2018
Dr Bernadette Carroll
Dr Viktor Korolchuk
Nutrient sensing, growth and senescence2018
Dr Bernadette Carroll
Diego Manni
Dr Rhoda Stefanatos
Fiona Menzies
Dr Graham Smith
et al.
Oxidation of SQSTM1/p62 mediates the link between redox state and protein homeostasis2018
Professor Robin Harris
Dr Viktor Korolchuk
Preface2018
Dr Yoshiki Hase
Dr Aiqing Chen
Dr Lucinda Craggs
Yumi Yamamoto
Lizzie Gemmell
et al.
Severe white matter astrocytopathy in CADASIL2018
Dr Viktor Korolchuk
Dr Kehe Huang
Dr XingXiang Chen
Taurine attenuates OTA-promoted PCV2 replication through blocking ROS-dependent autophagy via inhibiting AMPK/mTOR signaling pathway2018
Dr Dean Hallam
Dr Joseph Collin
Dr Sanja Bojic
Dr Valeria Chichagova
Dr Adriana Buskin
et al.
An iPSC patient specific model of CFH (Y402H) polymorphism displays characteristic features of AMD and indicates a beneficial role for UV light exposure2017
Dr Bernadette Carroll
Dr Viktor Korolchuk
Dysregulation of mTORC1/autophagy axis in senescence2017
Dr Viktor Korolchuk
Dr Satomi Miwa
Dr Bernadette Carroll
Professor Thomas von Zglinicki
Mitochondria in cell senescence: Is mitophagy the weakest link?2017
Dr Yoana Rabanal Ruiz
Gisela Otten
Dr Viktor Korolchuk
mTORC1 as the main gateway to autophagy2017
Dr Bernadette Carroll
Dr Glyn Nelson
Dr Yoana Rabanal Ruiz
Dr Olena Kucheryavenko
Professor Penny Lovat
et al.
Persistent mTORC1 signaling in cell senescence results from defects in amino acid and growth factor sensing2017
Dr Viktor Korolchuk
Selenomethionine Alleviates AFB1-Induced Damage in Primary Chicken Hepatocytes by Inhibiting CYP450 1A5 Expression via Upregulated SelW Expression2017
Dr Viktor Korolchuk
Dr James Murray
Signalling mechanisms in autophagy: An introduction to the issue2017
Dr Nuria Martinez Lopez
Gisela Otten
Dr Bernadette Carroll
Professor Rajat Singh
Dr Viktor Korolchuk
et al.
Autophagy, lipophagy and lysosomal lipid storage disorders2016
Dr Bernadette Carroll
Gisela Otten
Matthew Ratcliff
Dr Graham Smith
Dr Joao Passos
et al.
Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity2016
Dr Viktor Korolchuk
Dr Bernadette Carroll
Professor Penny Lovat
Dr Nuria Martinez Lopez
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd Ed.)2016
Dr Clara Correia Melo
Francisco Marques
Rhys Anderson
Dr Graeme Hewitt
Dr Bernadette Carroll
et al.
Mitochondria are required for pro-ageing features of the senescent phenotype2016
Gisela Otten
Diego Manni
Dr Viktor Korolchuk
Mitochondrial degradation, autophagy and neurodegenerative disease2016
Diego Manni
Dr Viktor Korolchuk
Oxidative Stress by Monoamine Oxidase-A Impairs Transcription Factor EB Activation and Autophagosome Clearance, Leading to Cardiomyocyte Necrosis and Heart Failure2016
Gisela Otten
Dr Viktor Korolchuk
PEG-lipid micelles enable cholesterol efflux in Niemann-Pick Type C1 disease-based lysosomal storage disorder2016
Dr Graeme Hewitt
Dr Viktor Korolchuk
Repair, Reuse, Recycle: The Expanding Role of Autophagy in Genome Maintenance2016
Dr Graeme Hewitt
Dr Bernadette Carroll
Dr Clara Correia Melo
Mikolaj Ogrodnik
Dr Glyn Nelson
et al.
SQSTM1/p62 mediates crosstalk between autophagy and the UPS in DNA repair2016
Dr Bernadette Carroll
Dr Long Xie
Professor Penny Lovat
Dr Viktor Korolchuk
Targeting the persistent activation of mammalian target of rapamycin in BRAF mutated melanoma as a novel therapeutic strategy2016
Dr Viktor Korolchuk
Dr Bernadette Carroll
Dr Long Xie
Carola Dostal
Professor Penny Lovat
et al.
Targeting the persistent activation of mTOR in B-RAF and NRas mutated melanoma as a novel therapeutic strategy2016
Dr Bernadette Carroll
Dr Viktor Korolchuk
Amino acids and autophagy: cross-talk and co-operation to control cellular homeostasis2015
Dr Graeme Hewitt
Dr Bernadette Carroll
Dr Viktor Korolchuk
Mechanisms of cross-talk between intracellular protein degradation pathways2015
Dr Viktor Korolchuk
Fiona Menzies
PI(5)P regulates autophagosome biogenesis2015
Dr Bernadette Carroll
Professor Penny Lovat
Dr Viktor Korolchuk
Targeting the persistent activation of mammalian target of rapamycin in BRAF- and NRas-mutated melanoma as a novel therapeutic strategy2015
Dr David McDonald
Dr Bernadette Carroll
Nicholas Robertson
Dr Helen Griffin
Professor Jeremy Lakey
et al.
Dual Proteolytic Pathways Govern Glycolysis and Immune Competence2014
Dr Piero Dalle Pezze
Dr Glyn Nelson
Gisela Otten
Dr Viktor Korolchuk
Emeritus Professor Thomas Kirkwood
et al.
Dynamic Modelling of Pathways to Cellular Senescence Reveals Strategies for Targeted Interventions2014
Dr Viktor Korolchuk
Restarting stalled autophagy a potential therapeutic approach for the lipid storage disorder, Niemann-Pick type C1 disease2014
Dr Bernadette Carroll
Dr Graeme Hewitt
Dr Viktor Korolchuk
Autophagy and ageing: implications for age-related neurodegenerative diseases2013
Dr Bernadette Carroll
Dr Viktor Korolchuk
Impaired Autophagy in the Lipid-Storage Disorder Niemann-Pick Type C1 Disease2013
Dr Viktor Korolchuk
Dr Joao Passos
Lysosome-mediated processing of chromatin in senescence2013
Dr Viktor Korolchuk
Guidelines for the use and interpretation of assays for monitoring autophagy2012
Dr Diana Jurk
Chunfang Wang
Dr Satomi Miwa
Mandy Maddick
Dr Viktor Korolchuk
et al.
Postmitotic neurons develop a p21-dependent senescence-like phenotype driven by a DNA damage response2012
Dr Viktor Korolchuk
A Phagocytic Route for Uptake of Double-Stranded RNA in RNAi2011
Dr Viktor Korolchuk
Complex inhibitory effects of nitric oxide on autophagy2011
Dr Viktor Korolchuk
Lysosomal positioning coordinates cellular nutrient responses2011
Dr Viktor Korolchuk
Antioxidants can inhibit basal autophagy and enhance neurodegeneration in models of polyglutamine disease2010
Dr Viktor Korolchuk
Impaired autophagy in Lafora disease2010
Dr Viktor Korolchuk
Laforin, the most common protein mutated in Lafora disease, regulates autophagy2010
Dr Viktor Korolchuk
Mechanisms of cross-talk between the ubiquitin-proteasome and autophagy-lysosome systems2010
Dr Viktor Korolchuk
Regulation of Mammalian Autophagy in Physiology and Pathophysiology2010
Dr Viktor Korolchuk
A CD317/tetherin–RICH2 complex plays a critical role in the organization of the subapical actin cytoskeleton in polarized epithelial cells2009
Dr Viktor Korolchuk
A novel link between autophagy and the ubiquitin-proteasome system2009
Dr Viktor Korolchuk
Autophagy Inhibition Compromises Degradation of Ubiquitin-Proteasome Pathway Substrates2009
Dr Viktor Korolchuk
In search of an “autophagomometer”2009
Dr Viktor Korolchuk
Mammalian macroautophagy at a glance2009
Dr Viktor Korolchuk
Methodological considerations for assessing autophagy modulators: A study with calcium phosphate precipitates2009
Dr Viktor Korolchuk
Huntington's disease: from pathology and genetics to potential therapies2008
Dr Viktor Korolchuk
Drosophila Vps35 function is necessary for normal endocytic trafficking and actin cytoskeleton organisation2007
Dr Viktor Korolchuk
Clathrin-mediated endocytosis of a lipid-raft-associated protein is mediated through a dual tyrosine motif2007
Dr Viktor Korolchuk
Eps15 and Dap160 control synaptic vesicle membrane retrieval and synapse development2007
Dr Viktor Korolchuk
Hippocalcin functions as a calcium sensor in hippocampal LTD2005
Dr Viktor Korolchuk
Regulation of CK2 activity by phosphatidylinositol phosphates2005
Dr Viktor Korolchuk
BST-2/HM1.24 is a raft-associated apical membrane protein with an unusual topology2003
Dr Viktor Korolchuk
Kinases in clathrin-mediated endocytosis2003
Dr Viktor Korolchuk
CK2 and GAK/auxilin2 are major protein kinases in clathrin-coated vesicles2002
Dr Viktor Korolchuk
Activation of plasminogen by antiplasminogen monoclonal antibody IV-1c: Properties and mechanism of reaction2000
Dr Viktor Korolchuk
Isolation and characterisation of antistreptokinase antibodies from blood serum of the patients treated by streptokinase1999
Dr Viktor Korolchuk
Plasminogen binding with decapeptide and polypeptide fragments of streptokinase1999
Dr Viktor Korolchuk
Val709-Glu724 streptokinase binding site of plasminogen interacts with streptokinase sequence Thr361-Arg372 during plasminogen - Streptokinase complex formation1999