Publications by Professor Ioakim Spyridopoulos - ePrints

Browsing publications by Professor Ioakim Spyridopoulos.

Newcastle Authors	Title	Year
Dr Jake McClements Dr Katarina Novakovic Professor Azfar Zaman Professor Ioakim Spyridopoulos Dr Marloes Peeters et al.	Immobilization of Molecularly Imprinted Polymer Nanoparticles onto Surfaces using Different Strategies: Evaluating the Influence of the Functionalised Interface on the Performance of a Thermal Assay for the Detection of Cardiac Biomarker Troponin I	2021
Jose Coelho Lima Junior Dr Georgios Georgiopoulos Dr Jannath Ahmed David Gaskin Dr Konstantinos Bakogiannis et al.	Prognostic value of admission high-sensitivity troponin in patients with ST-elevation myocardial infarction	2021
Dr Sarah Marsh Dr Catherine Park Dr Rachael Redgrave Dr Esha Singh Lilia Draganova et al.	Rapid fall in circulating non-classical monocytes in ST elevation myocardial infarction patients correlates with cardiac injury	2021
Dr Andrew Owens Dr Anna Walaszczyk Professor Ioakim Spyridopoulos Dr Emily Dookun Dr Gavin Richardson et al.	Senescence and Senolytics in Cardiovascular disease: Promise and Potential Pitfalls	2021
Jedrzej Hoffmann Dr Gavin Richardson Professor Ioakim Spyridopoulos	Telomerase As a Therapeutic Target in Cardiovascular Disease	2021
Professor Ioakim Spyridopoulos	Terminally Differentiated CD4⁺ T Cells Promote Myocardial Inflammaging	2021
Dr Catherine Park Dr Suzanne Cormack Dr Ashfaq Mohammed Dr Stephen Boag Dr Karim Bennaceur et al.	The Fractalkine Receptor CX3CR1 Links Lymphocyte Kinetics in CMV-Seropositive Patients and Acute Myocardial Infarction With Adverse Left Ventricular Remodeling	2021
Emily Dookun Dr Anna Walaszczyk Dr Rachael Redgrave Dr Pawel Palmowski Dr Simon Tual-Chalot et al.	Clearance of senescent cells during cardiac ischemia-reperfusion injury improves recovery	2020
Emily Dookun Dr Anna Walaszczyk Dr Rachael Redgrave Dr Pawel Palmowski Dr Simon Tual-Chalot et al.	Clearance of senescent cells during cardiac ischemia–reperfusion injury improves recovery	2020
Dr Carmen Martin-Ruiz Professor Thomas von Zglinicki Dr Gavin Richardson Lilia Draganova Dr Rachael Redgrave et al.	CMV-independent increase in CD27−CD28+ CD8+ EMRA T cells is inversely related to mortality in octogenarians	2020
Dr Suzanne Cormack Dr Alison Steel Dr Thomas Chadwick Andrew Bryant Dr Mohaned Egred et al.	Effect of ciclosporin on safety, lymphocyte kinetics and left ventricular remodelling in acute myocardial infarction	2020
Dr Mohaned Egred Dr Alan Bagnall Professor Ioakim Spyridopoulos Dr Rajiv Das Professor Azfar Zaman et al.	Effect of Pressure-controlled intermittent Coronary Sinus Occlusion (PiCSO) on infarct size in anterior STEMI: PiCSO in ACS study	2020
Dr Antoneta Granic Dr Carmen Martin-Ruiz Dr Richard Dodds Professor Dame Louise Robinson Professor Ioakim Spyridopoulos et al.	Immunosenescence profiles are not associated with muscle strength, physical performance and sarcopenia risk in very old adults: The Newcastle 85+ Study	2020
Danlin Liu Dr Gavin Richardson Fehmi Benli Dr Catherine Park Joao Victor de De Souza Cunha et al.	Inflammageing in the cardiovascular system: mechanisms, emerging targets, and novel therapeutic strategies	2020
Dr Nikolaos Vlachogiannis Dr Konstantinos Bakogiannis Professor Ioakim Spyridopoulos Professor Kimon Stamatelopoulos Professor Konstantinos Stellos et al.	Involvement of cardiovascular system as the critical point in coronavirus disease 2019 (COVID-19) prognosis and recovery	2020
Jose Coelho Lima Junior Dr Ashfaq Mohammed Dr Suzanne Cormack Adnan Ali Dr Matthew Barter et al.	Kinetics Analysis of Circulating MicroRNAs Unveils Markers of Failed Myocardial Reperfusion	2020
Dr Catherine Park Dr Suzanne Cormack Dr Stephen Boag Dr Karim Bennaceur Dr Gavin Richardson et al.	Role of CMV-serostatus and CX3CR1 on lymphocyte kinetics and left ventricular remodelling in patients with acute myocardial infarction	2020
Rebecca Maier Dr Bilal Bawamia Dr Karim Bennaceur Sarah Dunn Dr Leanne Marsay et al.	Telomerase activation to reverse immunosenescence in elderly patients with acute coronary syndrome: Protocol for a randomized pilot trial	2020
Professor Konstantinos Stellos Professor Ioakim Spyridopoulos	Exercise, telomerase activity, and cardiovascular disease prevention	2019
Emily Dookun Dr Anna Walaszczyk Dr Rachael Redgrave Dr Simon Tual-Chalot Oliver Yausep et al.	Navitoclax eliminates senescence attenuating remodelling and improving outcome to cardiac ischemia-reperfusion injury	2019
Dr Anna Walaszczyk Emily Dookun Dr Rachael Redgrave Dr Simon Tual-Chalot Professor Ioakim Spyridopoulos et al.	Pharmacological clearance of senescent cells improves survival and recovery in aged mice following acute myocardial infarction.	2019
Oliver Yausep Emily Dookun Dr Anna Walaszczyk Dr Rachael Redgrave Dr Simon Tual-Chalot et al.	The Effects of Senolytics on Murine Cardiac Function and Morphology Post-Ischemia Reperfusion Injury	2019
Peter Luke Dr Christopher Eggett Professor Ioakim Spyridopoulos Dr Timothy Irvine	A comparative analysis of British and American Society of Echocardiography recommendations for the assessment of left ventricular diastolic function	2018
Emily Dookun Dr Anna Walaszczyk Dr Rachael Redgrave Dr Simon Tual-Chalot Oliver Yausep et al.	Accumulation of cardiomyocyte senescence following ischaemia-reperfusion injury (IRI); a potential therapeutic target?	2018
Emily Dookun Dr Anna Walaszczyk Dr Rachael Redgrave Dr Simon Tual-Chalot Oliver Yausep et al.	Cardiomyocyte Senescence accumulates following Myocardial Infarction and Ischaemia-Reperfusion Injury.	2018
Professor Ioakim Spyridopoulos	CDKN1B/p27 is localized in mitochondria and improves respiration-dependent processes in the cardiovascular system—New mode of action for caffeine	2018
Professor Ioakim Spyridopoulos	Interventions to slow cardiovascular aging: Dietary restriction, drugs and novel molecules	2018
Professor Ioakim Spyridopoulos	Molecular mechanisms and therapy of cardiovascular ageing	2018
Professor Ioakim Spyridopoulos	Non-coding RNA regulation of T cell biology: Implications for age-associated cardiovascular diseases	2018
Dr Suzanne Cormack Samuel Jones Dr Rajiv Das Dr Mohaned Egred Professor Simi Ali et al.	Overcoming Heparin-Associated RT-qPCR Inhibition and Normalization Issues for microRNA Quantification in Patients with Acute Myocardial Infarction	2018
Dr Anna Walaszczyk Emily Dookun Dr Rachael Redgrave Dr Simon Tual-Chalot Rhys Anderson et al.	Senescence as a therapeutic target for myocardial ageing	2018
Dr Anna Walaszczyk Emily Dookun Dr Rachael Redgrave Professor Ioakim Spyridopoulos Professor Helen Arthur et al.	Senescence contributes age related cardiac dysfunction	2018
Dr Anna Walaszczyk Emily Dookun Dr Rachael Redgrave Professor Ioakim Spyridopoulos Professor Helen Arthur et al.	Senescence contributes to reduced survival and impaired cardiac function following myocardial infraction in aged mice.	2018
Dr Gavin Richardson Dr Karim Bennaceur Emily Dookun Lilia Draganova Dr Gabriele Saretzki et al.	Telomerase Mediates Lymphocyte Proliferation but Not the Atherosclerosis-Suppressive Potential of Regulatory T-Cells	2018
Dr Stephen Boag Dr Emanuele Andreano Professor Ioakim Spyridopoulos	Lymphocyte Communication in Myocardial Ischemia/Reperfusion Injury	2017
Professor Ioakim Spyridopoulos Professor Helen Arthur	Microvessels of the heart: Formation, regeneration and dysfunction	2017
Professor Ioakim Spyridopoulos	Telomere length in cardiovascular disease	2017
Professor Ioakim Spyridopoulos	Telomeres and cardiovascular diseases: Facts, controversies and limitations	2017
Dr Sarah Marsh Professor Helen Arthur Professor Ioakim Spyridopoulos	The secret life of nonclassical monocytes	2017
Professor Ioakim Spyridopoulos Dr Carmen Martin-Ruiz Dr Catharien Hilkens Mohammad Yadegarfar Professor John Isaacs et al.	CMV-seropositivity and T-cell senescence predict increased cardiovascular mortality in octogenarians - results from the Newcastle 85+ study	2016
Dr Evgeniya Shmeleva Dr Stephen Boag Santosh Murali Dr Karim Bennaceur Dr Rajiv Das et al.	Differences in immune responses between CMV-seronegative and -seropositive patients with myocardial ischemia and reperfusion	2015
Jedrzej Hoffmann Dr Evgeniya Shmeleva Dr Stephen Boag Dr Karel Fiser Dr Alan Bagnall et al.	Myocardial Ischemia and Reperfusion Leads to Transient CD8 Immune Deficiency and Accelerated Immunosenescence in CMV-Seropositive Patients	2015
Jedrzej Hoffmann Professor Ioakim Spyridopoulos	Senescent cytotoxic T cells in acute myocardial infarction: innocent bystanders or the horsemen of apocalypse?	2015
Professor Ioakim Spyridopoulos Dr Javed Ahmed Dr Rajiv Das Dr Richard Edwards Dr Alan Bagnall et al.	Shock-index as a novel predictor of long-term outcome following primary percutaneous coronary intervention	2015
Dr Stephen Boag Dr Rajiv Das Dr Evgeniya Shmeleva Dr Alan Bagnall Dr Mohaned Egred et al.	T lymphocytes and fractalkine contribute to myocardial ischemia/reperfusion injury in patients	2015
Dr Karim Bennaceur Mark Atwill Nayef Al Zhrany Jedrzej Hoffmann Professor Bernard Keavney et al.	Atorvastatin induces T cell proliferation by a telomerase reverse transcriptase (TERT) mediated mechanism	2014
Nouf Al-Ajmi Dr Gabriele Saretzki Dr Colin Miles Professor Ioakim Spyridopoulos	Dietary restriction ameliorates haematopoietic ageing independent of telomerase, whilst lack of telomerase and short telomeres exacerbate the ageing phenotype	2014
Dr Stephen Boag Dr Rajiv Das Dr Mohaned Egred Professor Azfar Zaman Dr Alan Bagnall et al.	Dynamic Changes in T-Lymphocyte Counts Following Primary Percutaneous Coronary Intervention Predict Infarct Size and Microvascular Obstruction	2014
Dr Evgeniya Shmeleva Dr Stephen Boag Santosh Murali Dr Karim Bennaceur Dr Stephen Todryk et al.	Effect of CMV-seropositivity on acute outcome of acute myocardial infarction	2014
Professor Ioakim Spyridopoulos Dr Javed Ahmed Dr Mohaned Egred	Shock-Index as a Novel Predictor of Longterm Outcome Following Primary Percutaneous Coronary Intervention	2014
Professor Ioakim Spyridopoulos Professor Thomas von Zglinicki	Telomere length predicts cardiovascular disease	2014
Dr Alan Bagnall Professor Ioakim Spyridopoulos	The evidence base for revascularisation of chronic total occlusions	2014
Professor Ioakim Spyridopoulos	Comparison of the Seattle Heart Failure Model and Cardiopulmonary Exercise Capacity for Prediction of Death in Patients With Chronic Ischemic Heart Failure and Intracoronary Progenitor Cell Application	2013
Professor Ioakim Spyridopoulos	Prognostic impact of using drug-eluting-stents on outcome and strategy in multivessel PCI: data from the Frankfurt MV-PCI registry	2013
Professor Azfar Zaman Dr Javed Ahmed Dr Mohaned Egred Professor Ioakim Spyridopoulos Professor Bernard Keavney et al.	Provision of Gastroprotective Medication and Bleeding Risk Following Acute Coronary Syndrome	2013
Professor Azfar Zaman Dr Javed Ahmed Dr Mohaned Egred Dr Richard Edwards Professor Ioakim Spyridopoulos et al.	Provision of Gastroprotective Medication and Bleeding Risk Following Acute Coronary Syndrome	2013
Professor Ioakim Spyridopoulos	Randomized trial of preventive angioplasty in myocardial infarction	2013
Professor Ioakim Spyridopoulos	Risk Stratification Following Complex PCI: Clinical Versus Anatomical Risk Stratification Including "Post PCI Residual SYNTAX-Score" as Quantification of Incomplete Revascularization	2013
Jedrzej Hoffmann Dr Karel Fiser Dr Jolanta Weaver Ian Dimmick Monika Loeher et al.	High-Throughput 13-Parameter Immunophenotyping Identifies Shifts in the Circulating T-Cell Compartment Following Reperfusion in Patients with Acute Myocardial Infarction	2012
Professor Ioakim Spyridopoulos	Impact of interventional strategy for unprotected left main coronary artery percutaneous coronary intervention on long-term survival	2012
Dr Mohaned Egred Dr Alan Bagnall Professor Ioakim Spyridopoulos Sheila Jamieson Dr Javed Ahmed et al.	Impact of thrombus aspiration during primary percutaneous coronary intervention on mortality in ST-segment elevation myocardial infarction	2012
Professor Ioakim Spyridopoulos	Microvascular dysfunction and pulse wave reflection characterize different vascular pathologies in patients at cardiovascular risk	2012
Dr Javed Ahmed Professor Ioakim Spyridopoulos Dr Alan Bagnall Dr Mohaned Egred	Mortality outcome of out-of-hours primary percutaneous coronary intervention in the current era	2012
Professor Ioakim Spyridopoulos	Is telomerase a potential target for vascular rejuvenation?	2011
Dr Vijay Kunadian Professor Azfar Zaman Professor Ioakim Spyridopoulos	Sodium bicarbonate for the prevention of contrast induced nephropathy: A meta-analysis of published clinical trials	2011
Professor Ioakim Spyridopoulos	Augmentation indices recorded from the radial artery and from the digital arteries provide the same information in patients under cardiovascular risk	2010
Professor Ioakim Spyridopoulos	Clinical Risk Stratification is a Better Determinant of Long-Term Survival Following Multivessel PCI Compared to Anatomic Risk Stratification Using the SYNTAX-Score	2010
Professor Ioakim Spyridopoulos	Comparison of the Seattle Heart Failure Model (SHFM) and Cardiopulmonary Exercise Testing (CPET) for Predicting Mortality of Patients With Ischemic Heart Failure	2010
Professor Ioakim Spyridopoulos	Complete Revascularization in Patients Undergoing Multivessel PCI is an Independent Predictor of Improved Long-term Survival	2010
Professor Ioakim Spyridopoulos	Idiopathic (unexplained) pulmonary embolism is associated with an impaired prognosis compared to other entities of pulmonary embolism	2010
Professor Ioakim Spyridopoulos	Intracoronary beta-radiation therapy for in-stent restenosis: long-term success rate and prediction of failure	2010
Professor Ioakim Spyridopoulos	Accelerated Telomere Shortening in CD8+T-lymphocytes From Patients With Coronary Heart Disease Links Cytomegalovirus-Induced T Cell Response and Deterioration of Myocardial Function	2009
Professor Ioakim Spyridopoulos	Accelerated Telomere Shortening in Leukocyte Subpopulations of Patients With Coronary Heart Disease: Role of Cytomegalovirus Seropositivity	2009
Professor Ioakim Spyridopoulos	Cardiac ³¹P-MRS compared to echocardiographic findings in patients with hypertensive heart disease without overt systolic dysfunction - preliminary results	2009
Professor Ioakim Spyridopoulos	Downregulation of ETS rescues diabetes-induced reduction of endothelial progenitor cells	2009
Professor Ioakim Spyridopoulos	Favorable Long-Term Survival in Patients Undergoing Multivessel-PCI Compared to Predicted Prognosis of CABG Estimated by EuroSCORE: Procedural and Clinical Determinants of Long-Term Outcome	2009
Professor Ioakim Spyridopoulos	Favorable long-term survival in patients undergoing stent PCI of unprotected left main coronary artery compared to predicted short-term prognosis of CABG estimated by EuroSCORE: clinical determinants of long-term outcome	2009
Professor Ioakim Spyridopoulos	Incidence, clinical characteristics, and long-term prognosis of travel-associated pulmonary embolism	2009
Professor Ioakim Spyridopoulos	Mitochondrial telomerase reverse transcriptase binds to and protects mitochondrial DNA and function from damage	2009
Professor Ioakim Spyridopoulos	Radial augmentation index unmasks premature coronary artery disease in younger males	2009
Professor Ioakim Spyridopoulos	Role of N-Terminal Pro-Brain Natriuretic Peptide and Cystatin C to Estimate Renal Function in Patients With and Without Heart Failure	2009
Professor Ioakim Spyridopoulos	Telomere length-heterogeneity among myeloid cells is a predictor for chronological ageing	2009
Professor Ioakim Spyridopoulos	Caffeine enhances endothelial repair by an AMPK-dependent mechanism	2008
Professor Ioakim Spyridopoulos	Mitochondrial p27 Is Required For Endothelial Energy Metabolism And Cell Migration	2008
Professor Ioakim Spyridopoulos	Nuclear Protein Tyrosine Phosphatase Shp-2 Is One Important Negative Regulator of Nuclear Export of Telomerase Reverse Transcriptase	2008
Professor Ioakim Spyridopoulos	Telomere gap between granulocytes and lymphocytes is a determinant for hematopoetic progenitor cell impairment in patients with previous myocardial infarction	2008
Professor Ioakim Spyridopoulos	The initial slope of the VCO2/VO2-curve (s1) in cardiopulmonary exercise testing is a strong and independent predictor of outcome in patients with previous myocardial infarction	2008