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Browsing publications by Professor Keith Jones.

Newcastle AuthorsTitleYearFull text
Dr Julie Tucker
Professor Keith Jones
Discovery of 4,6-disubstituted pyrimidines as potent inhibitors of the Heat Shock Factor (HSF1) stress pathway and CDK92016
Professor Keith Jones
Phosphorylation of histone H3 in 1- and 2-cell embryos2011
Professor Keith Jones
The APC/C activator FZR1 coordinates the timing of meiotic resumption during prophase I arrest in mammalian oocytes2011
Professor Keith Jones
The Aurora kinase inhibitor ZM447439 accelerates first meiosis in mouse oocytes by overriding the spindle assembly checkpoint2010
Iain Haslam
Professor Keith Jones
Professor Nicholas Simmons
Induction of P-glycoprotein expression and function in human intestinal epithelial cells (T84)2008
Professor Keith Jones
Meiosis in oocytes: Predisposition to aneuploidy and its increased incidence with age2008
Ibtissem Nabti
Dr Alexandra Reis
Dr Mark Levasseur
Professor Keith Jones
Securin and not CDK1/cyclin B1 regulates sister chromatid disjunction during meiosis II in mouse eggs2008
Professor Keith Jones
CaMKII can participate in but is not sufficient for the establishment of the membrane block to polyspermy in mouse eggs2007
Professor Keith Jones
Composition of sea urchin egg homogenate determines its potency to inositol trisphosphate and cyclic ADPRibose-induced Ca2+ release2007
Dr Suzanne Madgwick
Professor Keith Jones
How eggs arrest at metaphase II: MPF stabilisation plus APC/C inhibition equals cytostatic factor2007
Professor Keith Jones
Intracellular calcium in the fertilization and development of mammalian eggs2007
Dr Alexandra Reis
Dr Suzanne Madgwick
Ibtissem Nabti
Dr Mark Levasseur
Professor Keith Jones
et al.
Prometaphase APCcdh1 activity prevents non-disjunction in mammalian oocytes2007
Dr Alexandra Reis
Dr Mark Levasseur
Professor Keith Jones
APCcdh1 activity in mouse oocytes prevents entry into the first meiotic division2006
Dr Suzanne Madgwick
Professor Keith Jones
Calmodulin-dependent protein kinase II triggers mouse egg activation and embryo development in the absence of Ca2+ oscillations2006
Dr Alexandra Reis
Dr Suzanne Madgwick
Professor Keith Jones
Essential CDK1-inhibitory role for separase during meiosis I in vertebrate oocytes2006
Dr Suzanne Madgwick
Dr Mark Levasseur
Professor Keith Jones
Mouse Emi2 is required to enter meiosis II by reestablishing cyclin B1 during interkinesis2006
Dr Alexandra Reis
Dr Mark Levasseur
Professor David Elliott
Professor Keith Jones
The CRY box: A second APCcdh1-dependent degron in mammalian cdc202006
Dr Suzanne Madgwick
Dr Mark Levasseur
Professor Keith Jones
Calmodulin-dependent protein kinase II, and not protein kinase C, is sufficient for triggering cell-cycle resumption in mammalian eggs2005
Professor Keith Jones
Mammalian egg activation: From Ca2+ spiking to cell cycle progression2005
Professor Keith Jones
Phospholipase Cζ, the trigger egg activation in mammals, is present in a non-mammalian species2005
Dr Louise Hyslop
Dr Victoria Nixon
Dr Mark Levasseur
Fiona Chapman
Dr Alexander McDougall
et al.
Ca2+-promoted cyclin B1 degradation in mouse oocytes requires the establishment of a metaphase arrest2004
Dr Mark Levasseur
Professor Keith Jones
Degradation of APCcdc20 and APCcdh1 substrates during the second meiotic division in mouse eggs2004
Dr Suzanne Madgwick
Dr Victoria Nixon
Professor Mary Herbert
Dr Mark Levasseur
Professor Keith Jones
et al.
Maintenance of sister chromatid attachment in mouse eggs through maturation-promoting factor activity2004
Dr Julian Venables
Caroline Dalgliesh
Lindi Skitt
Dr Jared Thornton
Professor Keith Jones
et al.
SIAH1 targets the alternative splicing factor T-STAR for degradation by the proteasome2004
Professor Keith Jones
Turning it on and off: M-phase promoting factor during meiotic maturation and fertilization2004
Professor Keith Jones
Application of two-photon flash photolysis to reveal intercellular communication and intracellular Ca2+ movements2003
Professor Keith Jones
Erratum: Application of two-photon flash photolysis to reveal intercellular communication and intracellular Ca2+ movements (Journal of Biomedical Optics (July 2000) 8:3 (418-427))2003
Michael Carroll
Dr Mark Levasseur
Dr Chris Wood
Emeritus Professor Michael Whitaker
Professor Keith Jones
et al.
Exploring the mechanism of action of the sperm-triggered calcium-wave pacemaker in ascidian zygotes2003
Dr Victoria Nixon
Dr Mark Levasseur
Dr Alexander McDougall
Professor Keith Jones
Ca2+ oscillations promote APC/C-dependent cyclin B1 degradation during metaphase arrest and completion of meiosis in fertilizing mouse eggs2002
Dr Louise Hyslop
Dr Alexander McDougall
Professor Keith Jones
Identification of a novel delta-like human phospholipase C, which triggers Ca2+ oscillations in mammalian eggs2002
Professor Keith Jones
Membrane events in egg activation2002
Professor Keith Jones
Potential role of a sperm-derived phospholipase C in triggering the egg-activating Ca2+ signal at fertilization2001
Dr Louise Hyslop
Dr Victoria Nixon
Professor Keith Jones
Simultaneous measurement of intracellular nitric oxide and free calcium levels in chordate eggs demonstrates that nitric oxide has no role at fertilization2001
Dr Victoria Nixon
Professor Keith Jones
Ca2+ oscillations and the cell cycle at fertilisation of mammalian and ascidian eggs2000
Dr Alexander McDougall
Dr Mark Levasseur
Professor Keith Jones
Cell cycle-dependent repetitive Ca2+ waves induced by a cytosolic sperm extract in mature ascidian eggs mimic those observed at fertilization2000
Professor Keith Jones
Different Ca2+-releasing abilities of sperm extracts compared with tissue extracts and phospholipase C isoforms in sea urchin egg homogenate and mouse eggs2000
Professor Keith Jones
Injections of porcine extracts trigger fertilization-like calcium oscillations in oocytes of a marine worm2000
Professor Keith Jones
Mammalian sperm contain a Ca2+ -sensitive phospholipase C activity that can generate InsP3 from PIP2 associated with intracellular organelles2000
Professor Keith Jones
Dr Victoria Nixon
Sperm-induced Ca2+ oscillations in mouse oocytes and eggs can be mimicked by photolysis of caged inositol 1,4,5-trisphosphate: Evidence to support a continuous low level production of inositol 1,4,5-trisphosphate during mammalian fertilization2000
Professor Keith Jones
The soluble sperm factor that causes Ca2+ release from sea-urchin (Lytechinus pictus) egg homogenates also triggers Ca2+ oscillations after injection into mouse eggs1999