Iain Haslam Professor Nicholas Simmons
| Expression of the ABC transport proteins MDR1 (ABCB1) and BCRP (ABCG2) in bovine rumen | 2014 |
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Dr Ann Marie Hynes Dr Shalabh Srivastava Dr Lorraine Eley Dr Marina Danilenko Professor Peter Thelwall et al. | Murine Joubert syndrome reveals Hedgehog signaling defects as a potential therapeutic target for nephronophthisis | 2014 |
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Jamie Wright Professor Nicholas Simmons
| Breast cancer resistance protein BCRP (ABCG2)-mediated transepithelial nitrofurantoin secretion and its regulation in human intestinal epithelial (Caco-2) layers | 2011 |
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Jamie Wright Professor Nicholas Simmons
| Intestinal Ciprofloxacin Efflux: The Role of Breast Cancer Resistance Protein (ABCG2) | 2011 |
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Dr Georgina Carr Jamie Wright Professor Nicholas Simmons
| Epithelial Barrier Resistance is Increased by the Divalent Cation Zinc in Cultured MDCKII Epithelial Monolayers | 2010 |
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John Linley Dr Stefan Boese Professor Nicholas Simmons Dr Michael Gray
| A Voltage-Dependent Ca2+ Influx Pathway Regulates the Ca2+-Dependent Cl- Conductance of Renal IMCD-3 Cells | 2009 |
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Professor Nicholas Simmons Dr Abdul Chaudhry Dr Christopher Graham Dr Gavin Stewart
| Dietary regulation of ruminal bovine UT-B urea transporter expression and localization | 2009 |
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Dr Georgina Carr Dr Shabbir Moochhala Dr Lorraine Eley Professor Nicholas Simmons Professor John Sayer et al. | The Pyrophosphate Transporter ANKH is Expressed in Kidney and Bone Cells and Colocalises to the Primary Cilium/Basal Body Complex | 2009 |
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Iain Haslam Professor Keith Jones Professor Nicholas Simmons
| Induction of P-glycoprotein expression and function in human intestinal epithelial cells (T84) | 2008 |
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Professor John Sayer Dr Georgina Carr Dr Shabbir Moochhala Professor Nicholas Simmons
| Pyrophosphate transport and stones | 2008 |
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Professor John Sayer Dr Georgina Carr Dr Shabbir Moochhala Professor Nicholas Simmons
| Pyrophosphate Transport and Stones | 2008 |
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Iain Haslam Professor Nicholas Simmons
| Rifampin and digoxin induction of MDR1 expression and function in human intestinal (T84) epithelial cells | 2008 |
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Dr Georgina Carr Professor John Sayer Professor Nicholas Simmons
| Expression and localisation of the pyrophosphate transporter, ANK, in murine kidney cells | 2007 |
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Dr Christopher Graham Dr Ian Gatherar Iain Haslam Dr Michael Glanville Professor Nicholas Simmons et al. | Expression and localization of monocarboxylate transporters and sodium/proton exchangers in bovine rumen epithelium | 2007 |
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John Linley Professor Nicholas Simmons Dr Michael Gray
| Extracellular zinc stimulates a calcium-activated chloride conductance through mobilisation of intracellular calcium in renal inner medullary collecting duct cells | 2007 |
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Dr Georgina Carr Professor Nicholas Simmons Professor John Sayer
| Disruption of clc-5 leads to a redistribution of annexin A2 and promotes calcium crystal agglomeration in collecting duct epithelial cells | 2006 |
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Dr Georgina Carr Iain Haslam Professor Nicholas Simmons
| Voltage dependence of transepithelial guanidine permeation across Caco-2 epithelia allows determination of the paracellular flux component | 2006 |
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Dr Christopher Graham Professor Nicholas Simmons
| Characterization of a cDNA expressed in bovine rumen encoding a facilitative urea transporter | 2005 |
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Dr Christopher Graham Professor Nicholas Simmons
| Functional organization of the bovine rumen epithelium | 2005 |
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Dr Christopher Graham Professor Nicholas Simmons
| Functional organization of the bovine rumen epithelium | 2005 |
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Dr Gavin Stewart Dr Christopher Graham Professor Nicholas Simmons
| UT-B is expressed in bovine rumen: Potential role in ruminal urea transport | 2005 |
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Dr Stefan Boese Dr Michael Gray Professor Nicholas Simmons
| Volume-dependent and -independent activated anion conductances and their interaction in the renal inner medullary collecting duct (IMCD) | 2005 |
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Professor John Sayer Dr Georgina Carr Professor Nicholas Simmons
| Calcium phosphate and calcium oxalate crystal handling is dependent upon CLC-5 expression in mouse collecting duct cells | 2004 |
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Dr Stefan Boese Omar Aziz Professor Nicholas Simmons Dr Michael Gray
| Kinetics and regulation of a Ca2+-activated Cl- conductance in mouse renal inner medullary collecting duct cells | 2004 |
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Professor Nicholas Simmons Emeritus Professor Barry Hirst
| Comparison of poly(DL-lactide-co-glycolide) and polystyrene microsphere targeting to intestinal M cells | 2003 |
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Professor John Sayer Dr Georgina Carr Professor Simon Pearce Professor Tim Goodship Professor Nicholas Simmons et al. | Disordered calcium crystal handling in antisense CLC-5-treated collecting duct cells | 2003 |
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Professor Nicholas Simmons
| Evidence for a non-MDR1 component in digoxin secretion by human intestinal Caco-2 epithelial layers | 2003 |
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Dr Michael Gray Omar Aziz Professor Nicholas Simmons Dr Stefan Boese
| Intracellular Ca2+ directly regulates the Ca2+ activated Cl conductance in mouse inner medullary collecting duct cells | 2003 |
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Dr Stefan Boese Omar Aziz Professor Nicholas Simmons Dr Michael Gray
| Intracellular Ca2+ directly regulates the Ca2+-activated Cl- conductance in mouse inner medullary collecting duct cells | 2003 |
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Dr Georgina Carr Professor John Sayer Professor Nicholas Simmons
| Altered CLC-5 expression in mouse inner medullary collecting duct cells disrupts endocytosis and promotes calcium oxalate crystal adhesion | 2002 |
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Professor John Sayer Dr Georgina Carr Professor Nicholas Simmons Professor Tim Goodship
| Antisense CLC-5 disrupts acidic endosomes and endocytosis in murine collecting duct cells | 2002 |
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Professor David Thwaites Professor David Kennedy Dr Demetrio Raldua Dr Catriona Anderson Dr Ma Mendoza-Gomez et al. | H+/dipeptide absorption across the human intestinal epithelium is controlled indirectly via a functional Na+/H+ exchanger | 2002 |
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Dr Simon Lowes Professor Nicholas Simmons
| Multiple pathways for fluoroquinolone secretion by human intestinal epithelial (Caco-2) cells | 2002 |
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Dr Stefan Boese Professor John Sayer Dr Gavin Stewart Dr Michael Glanville Dr Michael Gray et al. | Renal expression of Ca2+-activated Cl- channels | 2002 |
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Dr Stefan Boese Professor John Sayer Dr Gavin Stewart Dr Michael Glanville Dr Michael Gray et al. | Renal expression of Ca2+-activated Cl- channels | 2002 |
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Professor John Sayer Professor Nicholas Simmons
| Urinary stone formation: Dent's disease moves understanding forward | 2002 |
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Professor David Thwaites Professor Nicholas Simmons
| Expression and role of sodium, potassium, chloride cotransport (NKCC1) in mouse inner medullary collecting duct (mIMCD-K2) epithelial cells | 2001 |
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Dr Simon Lowes Professor Nicholas Simmons
| Human intestinal cell monolayers are preferentially sensitive to disruption of barrier function from basolateral exposure to cholic acid: Correlation with membrane transport and transepithelial secretion | 2001 |
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Dr Catriona Anderson Dr Demetrio Raldua Professor Nicholas Simmons Professor David Thwaites
| pH-dependent forskolin modulation of beta-alanine uptake at the apical surface of Caco-2 cell monolayers | 2001 |
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Dr Gavin Stewart Omar Aziz Professor Nicholas Simmons Dr Michael Gray
| Regulation of an outwardly rectifying chloride conductance in renal epithelial cells by external and internal calcium | 2001 |
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Professor John Sayer Dr Gavin Stewart Dr Stefan Boese Dr Michael Gray Professor Simon Pearce et al. | The voltage-dependent of Cl- channel ClC-5 and plasma membrane Cl- conductances of mouse renal collecting duct cells (mIMCD-3) | 2001 |
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Dr Michael Gray Dr Colin Brown Professor Nicholas Simmons
| Bradykinin regulation of salt transport across mouse inner medullary collecting duct epithelium involves activation of a Ca2+ -dependent Cl- conductance | 2000 |
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Dr Stefan Boese Dr Michael Glanville Omar Aziz Dr Michael Gray Professor Nicholas Simmons et al. | Ca2+ and cAMP-activated Cl- conductances mediate Cl- secretion in a mouse renal inner medullary collecting duct cell line | 2000 |
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Professor David Thwaites Dr Laura Basterfield Professor Nicholas Simmons
| Gamma-aminobutyric acid (GABA) transport across human intestinal epithelial (Caco-2) cell monolayers | 2000 |
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Dr Stefan Boese Dr Michael Glanville Dr Michael Gray Professor Nicholas Simmons
| The swelling-activated anion conductance in the mouse renal inner medullary collecting duct cell line mIMCD-K2 | 2000 |
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Dr Stefan Boese Professor Nicholas Simmons Dr Michael Gray
| ATP and forskolin stimulate transepithelial Cl- secretion in mouse renal inner medullary collecting duct cells (mIMCD-K2) by activation of distinct Cl- conductances | 1999 |
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Dr Gavin Stewart Dr Michael Glanville Dr Michael Gray Professor Nicholas Simmons
| ATP stimulates a chloride conductance in the mIMCD-3 cell line | 1999 |
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Professor David Thwaites Professor Dianne Ford Dr Michael Glanville Professor Nicholas Simmons
| H+/solute-induced intracellular acidification leads to selective activation of apical Na+/H+ exchange in human intestinal epithelial cells | 1999 |
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Dr Stefan Boese Dr Michael Glanville Professor Nicholas Simmons Dr Michael Gray
| The swelling-activated chloride conductance in mIMCD-K2 cells is associated with multiple CLC expression. | 1999 |
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Professor Dianne Ford Professor David Thwaites Professor Nicholas Simmons Emeritus Professor Harry Gilbert Emeritus Professor Barry Hirst et al. | Substrate upregulation of the human small intestinal peptide transporter, hPepT1 | 1998 |
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Professor David Thwaites Professor Nicholas Simmons
| Na+-independent lysine transport in human intestinal Caco-2 cells | 1996 |
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Professor David Thwaites Emeritus Professor Barry Hirst Professor Nicholas Simmons
| Angiotensin-converting enzyme (ACE) inhibitor transport in human intestinal epithelial (Caco-2) cells | 1995 |
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Professor David Thwaites Emeritus Professor Barry Hirst Professor Nicholas Simmons
| D-Cycloserine transport in human intestinal epithelial (Caco-2) cells is mediated by a H+-coupled amino acid transporter | 1995 |
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Professor David Thwaites Professor Nicholas Simmons
| H+/di-tripeptide transporter (PepT1) expression in the rabbit intestine | 1995 |
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Professor David Thwaites Emeritus Professor Barry Hirst Professor Nicholas Simmons
| H+-coupled alpha-methylaminoisobutyric acid transport in human intestinal Caco-2 cells | 1995 |
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Professor David Thwaites Professor Nicholas Simmons
| The role of the proton electrochemical gradient in the transepithelial absorption of amino acids by human intestinal Caco-2 cell monolayers | 1995 |
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Professor David Thwaites Emeritus Professor Barry Hirst Professor Nicholas Simmons
| H+-coupled solute transport in cultured intestinal epithelia | 1994 |
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Professor David Thwaites Dr Colin Brown Emeritus Professor Barry Hirst Professor Nicholas Simmons
| L-Alanine absorption in human intestinal cells driven by the proton electrochemical gradient | 1994 |
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Professor David Thwaites Emeritus Professor Barry Hirst Professor Nicholas Simmons
| Substrate specificity of the di/tripeptide transporter in human intestinal epithelia (Caco-2): identification of substrates that undergo H+-coupled absorption | 1994 |
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Professor David Thwaites Emeritus Professor Barry Hirst Professor Nicholas Simmons
| Direct assessment of dipeptide/H+ symport in intact human intestinal (Caco-2) epithelium: a novel method utilising continuous intracellular pH measurement | 1993 |
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Professor David Thwaites Emeritus Professor Barry Hirst Professor Nicholas Simmons
| H+-coupled (Na+-independent) proline transport in human intestinal (Caco-2) epithelial cell monolayers | 1993 |
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Professor David Thwaites Dr Colin Brown Emeritus Professor Barry Hirst Professor Nicholas Simmons
| H+-coupled dipeptide (glycylsarcosine) transport across apical and basal borders of human intestinal Caco-2 cell monolayers display distinctive characteristics | 1993 |
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Professor David Thwaites Dr Colin Brown Emeritus Professor Barry Hirst Professor Nicholas Simmons
| Na+-independent, H+-coupled transepithelial beta-alanine absorption by human intestinal Caco-2 cell monolayers | 1993 |
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Professor David Thwaites Emeritus Professor Barry Hirst Professor Nicholas Simmons
| Passive transepithelial absorption of thyrotropin-releasing hormone (TRH) via a paracellular route in cultured intestinal and renal epithelial cell lines | 1993 |
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Professor David Thwaites Professor Nicholas Simmons Emeritus Professor Barry Hirst
| Thyrotropin-releasing hormone (TRH) uptake in intestinal brush-border membrane vesicles: comparison with proton-coupled dipeptide and Na+-coupled glucose transport | 1993 |
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Professor David Thwaites Emeritus Professor Barry Hirst Professor Nicholas Simmons
| Transepithelial dipeptide (glycylsarcosine) transport across epithelial monolayers of human Caco-2 cells is rheogenic | 1993 |
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Professor David Thwaites Dr Colin Brown Emeritus Professor Barry Hirst Professor Nicholas Simmons
| Transepithelial glycylsarcosine transport in intestinal Caco-2 cells mediated by expression of H+-coupled carriers at both apical and basal membranes | 1993 |
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