Toggle Main Menu Toggle Search

Open Access padlockePrints

Browsing publications by Professor Nicholas Simmons.

Newcastle AuthorsTitleYearFull text
Iain Haslam
Professor Nicholas Simmons
Expression of the ABC transport proteins MDR1 (ABCB1) and BCRP (ABCG2) in bovine rumen2014
Dr Ann Marie Hynes
Dr Shalabh Srivastava
Dr Lorraine Eley
Dr Marina Danilenko
Professor Peter Thelwall
et al.
Murine Joubert syndrome reveals Hedgehog signaling defects as a potential therapeutic target for nephronophthisis2014
Jamie Wright
Professor Nicholas Simmons
Breast cancer resistance protein BCRP (ABCG2)-mediated transepithelial nitrofurantoin secretion and its regulation in human intestinal epithelial (Caco-2) layers2011
Jamie Wright
Professor Nicholas Simmons
Intestinal Ciprofloxacin Efflux: The Role of Breast Cancer Resistance Protein (ABCG2)2011
Dr Georgina Carr
Jamie Wright
Professor Nicholas Simmons
Epithelial Barrier Resistance is Increased by the Divalent Cation Zinc in Cultured MDCKII Epithelial Monolayers2010
John Linley
Dr Stefan Boese
Professor Nicholas Simmons
Dr Michael Gray
A Voltage-Dependent Ca2+ Influx Pathway Regulates the Ca2+-Dependent Cl- Conductance of Renal IMCD-3 Cells2009
Professor Nicholas Simmons
Dr Abdul Chaudhry
Dr Christopher Graham
Dr Gavin Stewart
Dietary regulation of ruminal bovine UT-B urea transporter expression and localization2009
Dr Georgina Carr
Dr Shabbir Moochhala
Dr Lorraine Eley
Professor Nicholas Simmons
Professor John Sayer
et al.
The Pyrophosphate Transporter ANKH is Expressed in Kidney and Bone Cells and Colocalises to the Primary Cilium/Basal Body Complex2009
Iain Haslam
Professor Keith Jones
Professor Nicholas Simmons
Induction of P-glycoprotein expression and function in human intestinal epithelial cells (T84)2008
Professor John Sayer
Dr Georgina Carr
Dr Shabbir Moochhala
Professor Nicholas Simmons
Pyrophosphate transport and stones2008
Professor John Sayer
Dr Georgina Carr
Dr Shabbir Moochhala
Professor Nicholas Simmons
Pyrophosphate Transport and Stones2008
Iain Haslam
Professor Nicholas Simmons
Rifampin and digoxin induction of MDR1 expression and function in human intestinal (T84) epithelial cells2008
Dr Georgina Carr
Professor John Sayer
Professor Nicholas Simmons
Expression and localisation of the pyrophosphate transporter, ANK, in murine kidney cells2007
Dr Christopher Graham
Dr Ian Gatherar
Iain Haslam
Dr Michael Glanville
Professor Nicholas Simmons
et al.
Expression and localization of monocarboxylate transporters and sodium/proton exchangers in bovine rumen epithelium2007
John Linley
Professor Nicholas Simmons
Dr Michael Gray
Extracellular zinc stimulates a calcium-activated chloride conductance through mobilisation of intracellular calcium in renal inner medullary collecting duct cells2007
Dr Georgina Carr
Professor Nicholas Simmons
Professor John Sayer
Disruption of clc-5 leads to a redistribution of annexin A2 and promotes calcium crystal agglomeration in collecting duct epithelial cells2006
Dr Georgina Carr
Iain Haslam
Professor Nicholas Simmons
Voltage dependence of transepithelial guanidine permeation across Caco-2 epithelia allows determination of the paracellular flux component2006
Dr Christopher Graham
Professor Nicholas Simmons
Characterization of a cDNA expressed in bovine rumen encoding a facilitative urea transporter2005
Dr Christopher Graham
Professor Nicholas Simmons
Functional organization of the bovine rumen epithelium2005
Dr Christopher Graham
Professor Nicholas Simmons
Functional organization of the bovine rumen epithelium2005
Dr Gavin Stewart
Dr Christopher Graham
Professor Nicholas Simmons
UT-B is expressed in bovine rumen: Potential role in ruminal urea transport2005
Dr Stefan Boese
Dr Michael Gray
Professor Nicholas Simmons
Volume-dependent and -independent activated anion conductances and their interaction in the renal inner medullary collecting duct (IMCD)2005
Professor John Sayer
Dr Georgina Carr
Professor Nicholas Simmons
Calcium phosphate and calcium oxalate crystal handling is dependent upon CLC-5 expression in mouse collecting duct cells2004
Dr Stefan Boese
Omar Aziz
Professor Nicholas Simmons
Dr Michael Gray
Kinetics and regulation of a Ca2+-activated Cl- conductance in mouse renal inner medullary collecting duct cells2004
Professor Nicholas Simmons
Emeritus Professor Barry Hirst
Comparison of poly(DL-lactide-co-glycolide) and polystyrene microsphere targeting to intestinal M cells2003
Professor John Sayer
Dr Georgina Carr
Professor Simon Pearce
Professor Tim Goodship
Professor Nicholas Simmons
et al.
Disordered calcium crystal handling in antisense CLC-5-treated collecting duct cells2003
Professor Nicholas Simmons
Evidence for a non-MDR1 component in digoxin secretion by human intestinal Caco-2 epithelial layers2003
Dr Michael Gray
Omar Aziz
Professor Nicholas Simmons
Dr Stefan Boese
Intracellular Ca2+ directly regulates the Ca2+ activated Cl conductance in mouse inner medullary collecting duct cells2003
Dr Stefan Boese
Omar Aziz
Professor Nicholas Simmons
Dr Michael Gray
Intracellular Ca2+ directly regulates the Ca2+-activated Cl- conductance in mouse inner medullary collecting duct cells2003
Dr Georgina Carr
Professor John Sayer
Professor Nicholas Simmons
Altered CLC-5 expression in mouse inner medullary collecting duct cells disrupts endocytosis and promotes calcium oxalate crystal adhesion2002
Professor John Sayer
Dr Georgina Carr
Professor Nicholas Simmons
Professor Tim Goodship
Antisense CLC-5 disrupts acidic endosomes and endocytosis in murine collecting duct cells2002
Professor David Thwaites
Professor David Kennedy
Dr Demetrio Raldua
Dr Catriona Anderson
Dr Ma Mendoza-Gomez
et al.
H+/dipeptide absorption across the human intestinal epithelium is controlled indirectly via a functional Na+/H+ exchanger2002
Dr Simon Lowes
Professor Nicholas Simmons
Multiple pathways for fluoroquinolone secretion by human intestinal epithelial (Caco-2) cells2002
Dr Stefan Boese
Professor John Sayer
Dr Gavin Stewart
Dr Michael Glanville
Dr Michael Gray
et al.
Renal expression of Ca2+-activated Cl- channels2002
Dr Stefan Boese
Professor John Sayer
Dr Gavin Stewart
Dr Michael Glanville
Dr Michael Gray
et al.
Renal expression of Ca2+-activated Cl- channels2002
Professor John Sayer
Professor Nicholas Simmons
Urinary stone formation: Dent's disease moves understanding forward2002
Professor David Thwaites
Professor Nicholas Simmons
Expression and role of sodium, potassium, chloride cotransport (NKCC1) in mouse inner medullary collecting duct (mIMCD-K2) epithelial cells2001
Dr Simon Lowes
Professor Nicholas Simmons
Human intestinal cell monolayers are preferentially sensitive to disruption of barrier function from basolateral exposure to cholic acid: Correlation with membrane transport and transepithelial secretion2001
Dr Catriona Anderson
Dr Demetrio Raldua
Professor Nicholas Simmons
Professor David Thwaites
pH-dependent forskolin modulation of beta-alanine uptake at the apical surface of Caco-2 cell monolayers2001
Dr Gavin Stewart
Omar Aziz
Professor Nicholas Simmons
Dr Michael Gray
Regulation of an outwardly rectifying chloride conductance in renal epithelial cells by external and internal calcium2001
Professor John Sayer
Dr Gavin Stewart
Dr Stefan Boese
Dr Michael Gray
Professor Simon Pearce
et al.
The voltage-dependent of Cl- channel ClC-5 and plasma membrane Cl- conductances of mouse renal collecting duct cells (mIMCD-3)2001
Dr Michael Gray
Dr Colin Brown
Professor Nicholas Simmons
Bradykinin regulation of salt transport across mouse inner medullary collecting duct epithelium involves activation of a Ca2+ -dependent Cl- conductance2000
Dr Stefan Boese
Dr Michael Glanville
Omar Aziz
Dr Michael Gray
Professor Nicholas Simmons
et al.
Ca2+ and cAMP-activated Cl- conductances mediate Cl- secretion in a mouse renal inner medullary collecting duct cell line2000
Professor David Thwaites
Dr Laura Basterfield
Professor Nicholas Simmons
Gamma-aminobutyric acid (GABA) transport across human intestinal epithelial (Caco-2) cell monolayers2000
Dr Stefan Boese
Dr Michael Glanville
Dr Michael Gray
Professor Nicholas Simmons
The swelling-activated anion conductance in the mouse renal inner medullary collecting duct cell line mIMCD-K22000
Dr Stefan Boese
Professor Nicholas Simmons
Dr Michael Gray
ATP and forskolin stimulate transepithelial Cl- secretion in mouse renal inner medullary collecting duct cells (mIMCD-K2) by activation of distinct Cl- conductances1999
Dr Gavin Stewart
Dr Michael Glanville
Dr Michael Gray
Professor Nicholas Simmons
ATP stimulates a chloride conductance in the mIMCD-3 cell line1999
Professor David Thwaites
Professor Dianne Ford
Dr Michael Glanville
Professor Nicholas Simmons
H+/solute-induced intracellular acidification leads to selective activation of apical Na+/H+ exchange in human intestinal epithelial cells1999
Dr Stefan Boese
Dr Michael Glanville
Professor Nicholas Simmons
Dr Michael Gray
The swelling-activated chloride conductance in mIMCD-K2 cells is associated with multiple CLC expression.1999
Professor Dianne Ford
Professor David Thwaites
Professor Nicholas Simmons
Emeritus Professor Harry Gilbert
Emeritus Professor Barry Hirst
et al.
Substrate upregulation of the human small intestinal peptide transporter, hPepT11998
Professor David Thwaites
Professor Nicholas Simmons
Na+-independent lysine transport in human intestinal Caco-2 cells1996
Professor David Thwaites
Emeritus Professor Barry Hirst
Professor Nicholas Simmons
Angiotensin-converting enzyme (ACE) inhibitor transport in human intestinal epithelial (Caco-2) cells1995
Professor David Thwaites
Emeritus Professor Barry Hirst
Professor Nicholas Simmons
D-Cycloserine transport in human intestinal epithelial (Caco-2) cells is mediated by a H+-coupled amino acid transporter1995
Professor David Thwaites
Professor Nicholas Simmons
H+/di-tripeptide transporter (PepT1) expression in the rabbit intestine1995
Professor David Thwaites
Emeritus Professor Barry Hirst
Professor Nicholas Simmons
H+-coupled alpha-methylaminoisobutyric acid transport in human intestinal Caco-2 cells1995
Professor David Thwaites
Professor Nicholas Simmons
The role of the proton electrochemical gradient in the transepithelial absorption of amino acids by human intestinal Caco-2 cell monolayers1995
Professor David Thwaites
Emeritus Professor Barry Hirst
Professor Nicholas Simmons
H+-coupled solute transport in cultured intestinal epithelia1994
Professor David Thwaites
Dr Colin Brown
Emeritus Professor Barry Hirst
Professor Nicholas Simmons
L-Alanine absorption in human intestinal cells driven by the proton electrochemical gradient1994
Professor David Thwaites
Emeritus Professor Barry Hirst
Professor Nicholas Simmons
Substrate specificity of the di/tripeptide transporter in human intestinal epithelia (Caco-2): identification of substrates that undergo H+-coupled absorption1994
Professor David Thwaites
Emeritus Professor Barry Hirst
Professor Nicholas Simmons
Direct assessment of dipeptide/H+ symport in intact human intestinal (Caco-2) epithelium: a novel method utilising continuous intracellular pH measurement1993
Professor David Thwaites
Emeritus Professor Barry Hirst
Professor Nicholas Simmons
H+-coupled (Na+-independent) proline transport in human intestinal (Caco-2) epithelial cell monolayers1993
Professor David Thwaites
Dr Colin Brown
Emeritus Professor Barry Hirst
Professor Nicholas Simmons
H+-coupled dipeptide (glycylsarcosine) transport across apical and basal borders of human intestinal Caco-2 cell monolayers display distinctive characteristics1993
Professor David Thwaites
Dr Colin Brown
Emeritus Professor Barry Hirst
Professor Nicholas Simmons
Na+-independent, H+-coupled transepithelial beta-alanine absorption by human intestinal Caco-2 cell monolayers1993
Professor David Thwaites
Emeritus Professor Barry Hirst
Professor Nicholas Simmons
Passive transepithelial absorption of thyrotropin-releasing hormone (TRH) via a paracellular route in cultured intestinal and renal epithelial cell lines1993
Professor David Thwaites
Professor Nicholas Simmons
Emeritus Professor Barry Hirst
Thyrotropin-releasing hormone (TRH) uptake in intestinal brush-border membrane vesicles: comparison with proton-coupled dipeptide and Na+-coupled glucose transport1993
Professor David Thwaites
Emeritus Professor Barry Hirst
Professor Nicholas Simmons
Transepithelial dipeptide (glycylsarcosine) transport across epithelial monolayers of human Caco-2 cells is rheogenic1993
Professor David Thwaites
Dr Colin Brown
Emeritus Professor Barry Hirst
Professor Nicholas Simmons
Transepithelial glycylsarcosine transport in intestinal Caco-2 cells mediated by expression of H+-coupled carriers at both apical and basal membranes1993