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Browsing publications by Dr Carole Proctor.

Newcastle AuthorsTitleYearFull text
Rhys Anderson
Anthony Lagnado
Damien Maggiorani
Dr Anna Walaszczyk
Emily Dookun
et al.
Length‐independent telomere damage drives post‐mitotic cardiomyocyte senescence2019
Alvaro Martinez Guimera
Dr Daryl Shanley
Dr Carole Proctor
Modelling the role of redox-related mechanisms in musculoskeletal ageing2019
David Hodgson
Emeritus Professor Drew Rowan
Dr Carole Proctor
Systems biology reveals how altered TGFβ signalling with age reduces protection against pro-inflammatory stimuli2019
Alvaro Martinez Guimera
Ciaran Welsh
Dr Carole Proctor
Dr Daryl Shanley
'Molecular habituation' as a potential mechanism of gradual homeostatic loss with age2018
Dr ciaran Welsh
Dr Nicola Fullard
Dr Carole Proctor
Alvaro Martinez Guimera
Dr Daryl Shanley
et al.
PyCoTools: a Python toolbox for COPASI2018
Dr Carole Proctor
Dr Graham Smith
Computer simulation models as a tool to investigate the role of microRNAs in osteoarthritis2017
Dr Louise Pease
Dr Carole Proctor
Dr Daryl Shanley
Dr Simon Cockell
Cross platform analysis of transcriptomic data identifies ageing has distinct and opposite effects on tendon in males and females2017
Alvaro Martinez Guimera
David Hodgson
Neil McDonald
Dr Carole Proctor
Modelling the molecular mechanisms of aging2017
Dr Carole Proctor
Systems approaches in osteoarthritis: Identifying routes to novel diagnostic and therapeutic strategies2017
Dr Carole Proctor
Using computer simulation models to investigate the most promising microRNAs to improve muscle regeneration during ageing2017
Professor John Loughlin
Dr Carole Proctor
A proteomic analysis of chondrogenic, osteogenic and tenogenic constructs from ageing mesenchymal stem cells2016
Dr Michael Rushton
Professor John Loughlin
Dr Carole Proctor
Age-related Changes in Mesenchymal Stem Cells Identified Using a Multi-omics Approach2016
Michael Rushton
Professor John Loughlin
Dr Carole Proctor
Decoding the regulatory landscape of ageing in musculoskeletal engineered tissues using genome-wide DNA methylation and RNASeq2016
Dr Carole Proctor
Simulated interventions to ameliorate age-related bone loss indicate the importance of timing2016
Dr Carole Proctor
Examining the effects of loading/unloading and parathyroid hormone on bone homeostasis with computational models2015
Dr Carole Proctor
Christopher Macdonald
Dr Jenny Milner
Emeritus Professor Drew Rowan
Emeritus Professor Tim Cawston
et al.
A computer simulation approach for assessing therapeutic intervention points to prevent cytokine-induced cartilage breakdown2014
Professor David Young
Emeritus Professor Drew Rowan
Emeritus Professor Tim Cawston
Dr Carole Proctor
Investigating molecular mechanisms of ageing cartilage using computer simulation models2014
Professor David Young
Emeritus Professor Drew Rowan
Xin Xu
Emeritus Professor Tim Cawston
Dr Carole Proctor
et al.
Oxidative changes and signalling pathways are pivotal in initiating age-related changes in articular cartilage2014
Dr Carole Proctor
Christopher Macdonald
Dr Jenny Milner
Emeritus Professor Drew Rowan
Emeritus Professor Tim Cawston
et al.
A computer simulation approach for testing possible interventions to ameliorate collagen release2013
Dr Carole Proctor
Professor Doug Gray
Investigating Interventions in Alzheimer's Disease with Computer Simulation Models2013
Dr Carole Proctor
Dr Ilse Pienaar
Dr Joanna Elson
Emeritus Professor Thomas Kirkwood
Aggregation, impaired degradation and immunization targeting of amyloid-beta dimers in Alzheimer's disease: A stochastic modelling approach2012
Dr Carole Proctor
Modelling the Role of the Hsp70/Hsp90 System in the Maintenance of Protein Homeostasis2011
Dr Carole Proctor
Professor Doug Gray
Experimental and computational analysis of polyglutamine-mediated cytotoxicity2010
Dr Joao Passos
Dr Glyn Nelson
Dr Cedric Simillion
Dr Carole Proctor
Dr Satomi Miwa
et al.
Feedback between p21 and reactive oxygen production is necessary for cell senescence2010
Dr Carole Proctor
Professor Doug Gray
GSK3 and p53 - is there a link in Alzheimer's disease?2010
Dr Carole Proctor
Modelling the Role of UCH-L1 on Protein Aggregation in Age-Related Neurodegeneration2010
Dr Carole Proctor
Professor Doug Gray
Explaining oscillations and variability in the p53-Mdm2 system2008
Dr Carole Proctor
Professor Doug Gray
An in silico model of the ubiquitin-proteasome system that incorporates normal homeostasis and age-related decline2007
Dr Carole Proctor
Professor David Lydall
Professor Richard Boys
Dr Colin Gillespie
Dr Daryl Shanley
et al.
Modelling the checkpoint response to telomere uncapping in budding yeast2007
Torsten Richter
Dr Carole Proctor
The role of intracellular peroxide levels on the development and maintenance of telomere-dependent senescence2007
Dr Carole Proctor
Antipredator vigilance in birds: Modelling the 'edge' effect2006
Dr Colin Gillespie
Professor Darren Wilkinson
Dr Daryl Shanley
Dr Carole Proctor
Professor Richard Boys
et al.
BASIS: an internet resource for network modelling.2006
Dr Colin Gillespie
Professor Darren Wilkinson
Dr Carole Proctor
Dr Daryl Shanley
Professor Richard Boys
et al.
Tools for the SBML community2006
Dr Carole Proctor
Professor Richard Boys
Dr Colin Gillespie
Dr Daryl Shanley
Professor Darren Wilkinson
et al.
Modelling the actions of chaperones and their role in ageing2005
Dr Colin Gillespie
Dr Carole Proctor
Dr Daryl Shanley
Professor Darren Wilkinson
Professor Richard Boys
et al.
Web-services for the biology community: the BASIS project2005
Dr Colin Gillespie
Dr Carole Proctor
Professor Richard Boys
Dr Daryl Shanley
Professor Darren Wilkinson
et al.
A mathematical model of ageing in yeast2004
Dr Carole Proctor
A communication-based spatial model of antipredator vigilance2003
Dr Carole Proctor
Emeritus Professor Thomas Kirkwood
Modelling cellular senescence as a result of telomere state2003
Emeritus Professor Thomas Kirkwood
Dr Carole Proctor
Somatic mutations and ageing in silico2003
Emeritus Professor Thomas Kirkwood
Professor Richard Boys
Dr Colin Gillespie
Dr Carole Proctor
Dr Daryl Shanley
et al.
Towards an e-biology of ageing: Integrating theory and data2003
Dr Carole Proctor
Emeritus Professor Thomas Kirkwood
Modelling telomere shortening and the role of oxidative stress2002
Dr Carole Proctor
Modelling antipredator vigilance and flight response in group foragers when warning signals are ambiguous2001
Dr Carole Proctor
A spatial model of antipredator vigilance2000