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Browsing publications by
Professor Ian Hickson.
Newcastle Authors
Title
Year
Full text
Dr Beth Adamson
Nicholas Brittain
Dr Laura Walker
Ruaridh Duncan
Dr Sara Luzzi
et al.
The catalytic subunit of DNA-PK regulates transcription and splicing of AR in advanced prostate cancer
2023
Dr Natalie Tatum
Professor Ian Hickson
Targeting Mre11 overcomes platinum resistance and induces synthetic lethality in XRCC1 deficient epithelial ovarian cancers
2022
Islam Al-Khawaldeh
Dr Christine Basmadjian
Dr Cinzia Bordoni
Dr Suzannah Harnor
Amy Heptinstall
et al.
An alkynylpyrimidine-based covalent inhibitor that targets a unique cysteine in NF-κB-inducing kinase (NIK)
2021
Professor Ian Hickson
Discovery of JNJ-63576253, a next-generation androgen receptor antagonist active against wild-type and clinically relevant ligand binding domain mutations in metastatic castration-resistant prostate cancer
2021
Professor Ian Hickson
Discovery of JNJ-63576253: A Clinical Stage Androgen Receptor Antagonist for F877L Mutant and Wild-Type Castration-Resistant Prostate Cancer (mCRPC)
2021
Professor Ian Hickson
Dr Natalie Tatum
FEN1 Blockade for Platinum Chemo-Sensitization and Synthetic Lethality in Epithelial Ovarian Cancers
2021
Professor Ian Hickson
Modulating Androgen Receptor-Driven Transcription in Prostate Cancer with Selective CDK9 Inhibitors
2021
Professor Ian Hickson
USP45 and Spindly are part of the same complex implicated in cell migration
2018
Professor Ian Hickson
Substituted Thiohydantoin Derivatives as Androgen Receptor Antagonists
2017
Professor Ian Hickson
The fluorescent two-hybrid assay for live-cell profiling of androgen receptor modulators
2017
Professor Ian Hickson
A high-throughput PPI assay to quantify inhibition of androgen receptor variant 7 (AR-V7) binding to canonical AR full-length (AR-FL) binding partners
2016
Professor Ian Hickson
Live-cell profiling of inhibitors targeting the N/C interaction within the androgen receptor
2015
Professor Ian Hickson
USP45 deubiquitylase controls ERCC1-XPF endonuclease mediated DNA damage responses
2015
Professor Ian Hickson
In vitro
co-culture model to study adrenal stimulus of CRPC
2014
Professor Ian Hickson
Adrenal stimulation of CRPC growth in an in vitro co-culture model.
2014
Professor Ian Hickson
Complex
in vitro
and
in vivo
prostate cancer models for the PREDECT consortium
2014
Professor Ian Hickson
Disrupting p53:Mdm2 and p53:Mdm4 - Comparative cell-based assays for drug screening
2014
Professor Ian Hickson
Initial testing (stage 1) of the histone deacetylase inhibitor, quisinostat (JNJ-26481585), by the Pediatric Preclinical Testing Program
2014
Professor Ian Hickson
The Fluorescent Two-Hybrid Assay to Screen for Protein–Protein Interaction Inhibitors in Live Cells: Targeting the Interaction of p53 with Mdm2 and Mdm4
2014