Publications by Professor Ian Hickson - ePrints

Browsing publications by Professor Ian Hickson.

Newcastle Authors	Title	Year
Professor Ian Hickson	S-Aryl Substitution Enhances Acidity of the 1,2,4-Triazolium Scaffold	2024
Dr Beth Adamson Nicholas Brittain Dr Laura Walker Ruaridh Duncan Dr Sara Luzzi et al.	The catalytic subunit of DNA-PK regulates transcription and splicing of AR in advanced prostate cancer	2023
Dr Natalie Tatum Professor Ian Hickson	Targeting Mre11 overcomes platinum resistance and induces synthetic lethality in XRCC1 deficient epithelial ovarian cancers	2022
Islam Al-Khawaldeh Dr Christine Basmadjian Dr Cinzia Bordoni Dr Suzannah Harnor Amy Heptinstall et al.	An alkynylpyrimidine-based covalent inhibitor that targets a unique cysteine in NF-κB-inducing kinase (NIK)	2021
Professor Ian Hickson	Discovery of JNJ-63576253, a next-generation androgen receptor antagonist active against wild-type and clinically relevant ligand binding domain mutations in metastatic castration-resistant prostate cancer	2021
Professor Ian Hickson	Discovery of JNJ-63576253: A Clinical Stage Androgen Receptor Antagonist for F877L Mutant and Wild-Type Castration-Resistant Prostate Cancer (mCRPC)	2021
Professor Ian Hickson Dr Natalie Tatum	FEN1 Blockade for Platinum Chemo-Sensitization and Synthetic Lethality in Epithelial Ovarian Cancers	2021
Professor Ian Hickson	Modulating Androgen Receptor-Driven Transcription in Prostate Cancer with Selective CDK9 Inhibitors	2021
Professor Ian Hickson	USP45 and Spindly are part of the same complex implicated in cell migration	2018
Professor Ian Hickson	Substituted Thiohydantoin Derivatives as Androgen Receptor Antagonists	2017
Professor Ian Hickson	The fluorescent two-hybrid assay for live-cell profiling of androgen receptor modulators	2017
Professor Ian Hickson	A high-throughput PPI assay to quantify inhibition of androgen receptor variant 7 (AR-V7) binding to canonical AR full-length (AR-FL) binding partners	2016
Professor Ian Hickson	Live-cell profiling of inhibitors targeting the N/C interaction within the androgen receptor	2015
Professor Ian Hickson	USP45 deubiquitylase controls ERCC1-XPF endonuclease mediated DNA damage responses	2015
Professor Ian Hickson	In vitro co-culture model to study adrenal stimulus of CRPC	2014
Professor Ian Hickson	Adrenal stimulation of CRPC growth in an in vitro co-culture model.	2014
Professor Ian Hickson	Complex in vitro and in vivo prostate cancer models for the PREDECT consortium	2014
Professor Ian Hickson	Disrupting p53:Mdm2 and p53:Mdm4 - Comparative cell-based assays for drug screening	2014
Professor Ian Hickson	Initial testing (stage 1) of the histone deacetylase inhibitor, quisinostat (JNJ-26481585), by the Pediatric Preclinical Testing Program	2014
Professor Ian Hickson	The Fluorescent Two-Hybrid Assay to Screen for Protein–Protein Interaction Inhibitors in Live Cells: Targeting the Interaction of p53 with Mdm2 and Mdm4	2014