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Browsing publications by Dr Natalie Tatum.

Newcastle AuthorsTitleYearFull text
Rhianna Rowland
Svitlana Korolchuk
Dr Marco Salamina
Dr Natalie Tatum
Professor Martin Noble
et al.
Cryo-EM structure of the CDK2-cyclin A-CDC25A complex2024
Dr Martyna Pastok
Dr Shannon Turberville
Dr Arnaud Basle
Professor Martin Noble
Professor Jane Endicott
et al.
Structural requirements for the specific binding of CRABP2 to cyclin D32024
Dr Mathew Martin
Professor Jane Endicott
Professor Martin Noble
Dr Natalie Tatum
Crystallographic fragment screening in academic cancer drug discovery2023
Dr Mat Bieniek
Ben Cree
Dr Rachael Pirie
Josh Horton
Dr Natalie Tatum
et al.
An Open-Source Molecular Builder and Free Energy Preparation Workflow2022
Dr Natalie Tatum
Professor Ian Hickson
Targeting Mre11 overcomes platinum resistance and induces synthetic lethality in XRCC1 deficient epithelial ovarian cancers2022
Dr Marco Salamina
Dr Richard Heath
Svitlana Korolchuk
Dr Arnaud Basle
Dr Martyna Pastok
et al.
Discriminative SKP2 Interactions with CDK-Cyclin Complexes Support a Cyclin A-Specific Role in p27KIP1 Degradation2021
Professor Ian Hickson
Dr Natalie Tatum
FEN1 Blockade for Platinum Chemo-Sensitization and Synthetic Lethality in Epithelial Ovarian Cancers2021
Dr Natalie Tatum
Professor Jane Endicott
Chatterboxes: the structural and functional diversity of cyclins2020
Dr Natalie Tatum
Professor Martin Noble
Paradoxical activation of the protein kinase-transcription factor ERK5 by ERK5 kinase inhibitors2020
Daniel Wood
Svitlana Korolchuk
Dr Natalie Tatum
Lan Wang
Professor Jane Endicott
et al.
Differences in the conformational energy landscape of CDK1 and CDK2 suggest a mechanism for achieving selective CDK inhibition2019
Dr Natalie Tatum
Relative binding energies predict crystallographic binding modes of ethionamide booster lead compounds2019
Dr Natalie Tatum
The diverse structural landscape of quadruplexes2019
Hesham Haffez
Dr Natalie Tatum
Dr Chris Redfern
Probing biological activity through structural modelling of ligand-receptor interactions of 2,4-disubstituted thiazole retinoids2018
Dr Natalie Tatum
New leads for Tuberculosis booster drugs by structure-based drug discovery2017
Dr Natalie Tatum
Synthesis, Ni(II) Schiff base complexation and structural analysis of fluorinated analogs of the ligand (S)-2-[N-(N′-benzylprolyl) amino] benzophenone (BPB)2015