Dr Amir Enshaei Dr Sirintra Nakjang Lynne Minto Professor Julie Irving Beth Poole et al. | The genomic landscape of teenage and young adult T-cell acute lymphoblastic leukemia | 2021 |
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Dr Britta Vormoor Professor Gareth Veal Melanie Griffin Professor Julie Irving Lynne Minto et al. | A phase I/II trial of AT9283, a selective inhibitor of aurora kinase in children with relapsed or refractory acute leukemia: challenges to run early phase clinical trials for children with leukemia | 2017 |
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Professor Julie Irving Dr Amir Enshaei Dr Amy Erhorn Lynne Minto Claire Schwab et al. | Integration of genetic and clinical risk factors improves prognostication in relapsed childhood B-cell precursor acute lymphoblastic leukaemia | 2016 |
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Dr Sarra Ryan Elizabeth Matheson Dr Paul Sinclair Dr Matthew Bashton Claire Schwab et al. | The role of the RAS pathway in iAMP21-ALL | 2016 |
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Professor Anthony Moorman Professor Julie Irving Dr Amir Enshaei Dr Amy Erhorn Lynne Minto et al. | Composite Index for Risk Prediction in Relapsed Childhood Acute Lymphoblastic Leukaemia | 2015 |
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Dr Lindsay Nicholson Dr Emily Mavin Lynne Minto Professor Julie Irving Professor Anne Dickinson et al. | Gene Expression Profiling Implicates Attenuation of NFkB Signalling By Regulatory T Cells in Modulating Dendritic Cell Function | 2015 |
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Dr Lindsay Nicholson Dr Emily Mavin Lynne Minto Professor Julie Irving Professor Anne Dickinson et al. | Gene Expression Profiling Implicates Attenuation of NFkB Signalling By Regulatory T Cells in Modulating Dendritic Cell Function | 2015 |
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Dr Lindsay Nicholson Elizabeth Matheson Lynne Minto Christopher Keilty Maryna Sanichar et al. | Quantitative proteomic analysis reveals maturation as a mechanism underlying glucocorticoid resistance in B lineage ALL and re-sensitization by JNK inhibition | 2015 |
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Dr Lindsay Nicholson Elizabeth Matheson Lynne Minto Marian Case Maryna Sanichar et al. | Casitas B lymphoma mutations in childhood acute lymphoblastic leukemia | 2012 |
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Dr Vikki Rand Dr Lisa Russell Claire Schwab Hannah Ensor Professor Julie Irving et al. | Genomic characterization implicates iAMP21 as a likely primary genetic event in childhood B-cell precursor acute lymphoblastic leukemia | 2011 |
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Dr Lindsay Nicholson Charlotte Evans Elizabeth Matheson Lynne Minto Christopher Keilty et al. | Quantitative Proteomic Analysis Reveals Maturation As a Mechanism Underlying Glucocorticoid Resistance in Childhood Acute Lymphoblastic Leukemia and PAX5 As a Re-Sensitising Therapeutic Target | 2011 |
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Dr Sarra Ryan Dr Vikki Rand Claire Schwab Heather Morrison Elizabeth Matheson et al. | Ras Signalling Pathway and Novel Target Genes Related to Down Syndrome Contribute to the Development of B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) in iAMP21 Patients | 2011 |
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Elizabeth Matheson Lynne Minto Dr Andrew Hall Professor Julie Irving
| Mismatch repair and the downstream target genes, PAX5 and Ikaros, in childhood acute lymphoblastic leukemia | 2010 |
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Professor Julie Irving Marian Case Lynne Minto Sally Lawson
| Establishment and validation of a standard protocol for the detection of minimal residual disease in B lineage childhood acute lymphoblastic leukemia by flow cytometry in a multi-center setting | 2009 |
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Kate Wilson Marian Case Lynne Minto Professor Simon Bailey Dr Nicholas Bown et al. | Flow minimal residue disease monitoring of candidate leukemic stem cells defined by the immunophenotype, CD34+CD38lowCD19+ in B-lineage childhoood acute lymphoblastic leukemia | 2009 |
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Dr Lindsay Nicholson Elizabeth Matheson Lynne Minto Christopher Keilty Dr Andrew Hall et al. | Quantitative Proteomic Analysis Implicates An Altered B-Cell Differentiation State as a Mechanism Underlying GC-Resistance in An Acute Lymphoblastic Leukaemia (ALL) Cell Line Model | 2009 |
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Dr Vikki Rand Dr Lisa Russell Professor Julie Irving Lisa Jones Dr Dino Masic et al. | What Is the Initiating Mechanism of iAMP21 in Childhood B Cell Precursor ALL? | 2009 |
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Professor Julie Irving Lynne Minto Dr Andrew Hall
| Genomic analysis of different clonal evolution in a twin pair with t(12;21) positive acute lymphoblastic leukemia sharing the same prenatal clone [8] | 2008 |
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Elizabeth Matheson Lynne Minto Professor Anthony Moorman Dr Andrew Hall Professor Julie Irving et al. | Heterogeneous breakpoints target PAX5 in acute lymphoblastic leukaemia patients with dicentric chromosomes | 2008 |
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Professor Anthony Moorman Sarina Sulong Professor Julie Irving Marian Case Lynne Minto et al. | Inactivation of CDKN2A in childhood acute lymphoblastic leukaemia (ALL) occurs principally by deletion and is strongly correlated with cytogenetic subgroups | 2008 |
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Marian Case Elizabeth Matheson Lynne Minto Dr Nicholas Bown Professor Simon Bailey et al. | Mutation of genes affecting the RAS pathway is common in childhood acute lymphoblastic leukemia | 2008 |
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Marian Case Elizabeth Matheson Lynne Minto Professor Christine Harrison FRCPath FMedSci Dr Nicholas Bown et al. | Somatic mutation of genes impacting on the RAS-RAF-MEK-ERK pathway is the most common genetic abnormality in childhood acute lymphoblastic leukaemia, is implicated in disease progression and provides a rationale for therapeutic targeting | 2008 |
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Kerrie Wilson Marian Case Lynne Minto Professor Simon Bailey Professor Hermann Josef Vormoor et al. | The CD34+ CD38Low CD19+ Candidate Leukemic Stem Cell Phenotype Revisited: Useful for Flow MRD Monitoring? | 2008 |
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Adillah Binti Yusof Professor Julie Irving Marian Case Lynne Minto Professor Christine Harrison FRCPath FMedSci et al. | Red blood cell alloimmunization is affected by depletion of donor white cell subsets | 2007 |
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Elizabeth Matheson Lynne Minto Professor Anthony Moorman Dr Andrew Hall Professor Julie Irving et al. | Variable Breakpoints Target PAX5 in Patients with Dicentric Chromosomes: A Model for the Basis of Unbalanced Translocations in Cancer | 2007 |
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Dr Andrew Hall Sarina Sulong Professor Christine Harrison FRCPath FMedSci Lynne Minto Dr Nicholas Bown et al. | Assessment of aneuploidy in childhood acute lymphoblastic leukaemia using high density oligonucleotide arrays. | 2006 |
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Sarina Sulong Professor Julie Irving Marian Case Lynne Minto Dr Nicholas Bown et al. | Comprehensive analysis of p16(INK4a) in childhood acute lymphoblastic leukemia reveals homozygous deletion, haploinsufficiency and acquired isodisomy at the 9p locus with intact p16(INK4a). | 2006 |
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Professor Julie Irving Lynne Minto Elizabeth Matheson Dr Lindsay Nicholson Dr Andrew Hall et al. | Glucocorticoid resistance in two key models of acute lymphoblastic leukemia occurs at the level of the glucocorticoid receptor | 2006 |
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Professor Julie Irving Lynne Minto Elizabeth Matheson Marian Case Professor Simon Bailey et al. | Mutation in genes impacting on the RAS-RAF-MEK-ERK pathway are found at high incidence in childhood acute lymphoblastic leukemia at both diagnosis and at relapse. | 2006 |
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Dr Andrew Hall Professor Julie Irving Lynne Minto
| Reply to 'ATM variants and predisposition to childhood T-lineage acute lymphoblastic leukaemia' by Gumy-Pause et al. [6] | 2006 |
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Professor Julie Irving Lynne Minto Professor Simon Bailey Dr Andrew Hall
| Loss of heterozygosity and somatic mutations of the Glucocorticoid receptor gene are rarely found at relapse in pediatric acute lymphoblastic leukemia but may occur in a subpopulation early in the disease course | 2005 |
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Monique Lhussier Lynne Minto
| Paradoxes, locations and the need for social coherence: a qualitative study of living with a learning difficulty | 2005 |
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Dr Andrew Hall Professor Julie Irving Lynne Minto
| Relation between genetic variants of the ataxia telangiectasia-mutated (ATM) gene, drug resistance, clinical outcome and predisposition to childhood T-lineage acute lymphoblastic leukaemia | 2005 |
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Sarina Sulong Marian Case Lynne Minto Dr Bridget Wilkins Dr Andrew Hall et al. | The V617F mutation in Jak2 is not found in childhood acute lymphoblastic leukaemia | 2005 |
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Dr Sandeep Pal Lynne Minto Dr Andrew Hall
| Antibodies against 9-O-acetylated sialoglycans: A potent marker to monitor clinical status in childhood acute lymphoblastic leukemia | 2004 |
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Dr Andrew Hall Professor Julie Irving Lynne Minto
| Genetic variants of ataxia telangiectasia mutated (ATM) and susceptibility for childhood T-lineage acute lymphoblastic leukemia. | 2004 |
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Professor Julie Irving Professor Stephen O'Brien Dr Anne Lennard Lynne Minto Dr Feng Lin et al. | Use of Denaturing HPLC for Detection of Mutations in the BCR-ABL Kinase Domain in Patients Resistant to Imatinib | 2004 |
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Dr Sally Coulthard Dr Linda Hogarth Dr Margaret Little Elizabeth Matheson Dr Chris Redfern et al. | The effect of thiopurine methyltransferase expression on sensitivity to thiopurine drugs | 2002 |
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Dr Linda Hogarth Lynne Minto
| Enhanced expression and activity of DNA polymerase β in human ovarian tumor cells: impact on sensitivity towards antitumor agents | 2001 |
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Dr Linda Hogarth Dr Margaret Little Lynne Minto Dr Chris Redfern Dr Andrew Hall et al. | High thiopurine methyltransferase expression confers different levels of resistance with 6-thioguanine compared to 6-mercaptopurine. | 2001 |
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Dr Linda Hogarth Dr Margaret Little Lynne Minto Dr Chris Redfern Dr Andrew Hall et al. | In vitro evidence for differences in 6-mercaptopurine versus 6-thioguanine metabolism depending on TPMT status | 2001 |
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Dr Andrew Hall Dr Peter Hamilton Lynne Minto Dr Sally Coulthard
| The use of denaturing high-pressure liquid chromatography for the detection of mutations in thiopurine methyltransferase | 2001 |
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Dr Sally Coulthard Dr Christopher Howell Lynne Minto Dr Peter Middleton Professor Graham Jackson et al. | A comparison of molecular and enzyme-based assays for the detection of thiopurine methyltransferase mutations | 2000 |
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Dr Sally Coulthard Dr Linda Hogarth Lynne Minto Dr Chris Redfern Dr Andrew Hall et al. | High thiopurine methyltransferase expression confers different levels of resistance with 6-thioguanine compared to 6-mercaptopurine | 2000 |
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Dr Linda Hogarth Elizabeth Matheson Lynne Minto Dr Margaret Little Dr Andrew Hall et al. | Measurement of resistance to thiopurine drugs in cells with defective mismatch repair | 2000 |
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