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Browsing publications by
Dr David Samuels
Newcastle Authors
Title
Year
Full text
Christoph Freyer
Dr Lynsey Cree
Dr Jim Stewart
Dr Vasileios Floros
Dr David Samuels
et al.
Variation in germline mtDNA heteroplasmy is determined prenatally but modified during subsequent transmission
2012
Dr Brendan Payne
Dr Ian Wilson
Professor Rita Horvath
Dr Mauro Santibanez Koref
Dr David Samuels
et al.
Mitochondrial aging is accelerated by anti-retroviral therapy through the clonal expansion of mtDNA mutations
2011
Joanna Stewart
Kamil Sitarz
Professor Rita Horvath
Dr Angela Pyle
Dr Patrick Yu Wai Man
et al.
POLG mutations cause decreased mitochondrial DNA repopulation rates following induced depletion in human fibroblasts
2011
Dr Patrick Yu Wai Man
Kamil Sitarz
Dr David Samuels
Philip Griffiths
Dr Amy Reeve
et al.
OPA1
mutations cause cytochrome
c
oxidase deficiency due to loss of wild-type mtDNA molecules
2010
Professor Patrick Chinnery
Dr David Samuels
Previous Estimates of Mitochondrial DNA Mutation Level Variance Did Not Account for Sampling Error: Comparing the mtDNA Genetic Bottleneck in Mice and Humans
2010
Dr David Samuels
Professor David Burn
Professor Patrick Chinnery
Detecting new neurodegenerative disease genes: does phenotype accuracy limit the horizon?
2009
Dr Lynsey Cree
Dr David Samuels
Professor Patrick Chinnery
The inheritance of pathogenic mitochondrial DNA mutations
2009
Dr Hannah Elliott
Dr David Samuels
James Eden
Professor Caroline Relton
Professor Patrick Chinnery
Pathogenic Mitochondrial DNA Mutations Are Common in the General Population
2008
Professor Patrick Chinnery
Dr David Samuels
Selection against Pathogenic mtDNA Mutations in a Stem Cell Population Leads to the Loss of the 3243A→G Mutation in Blood
2008
Professor Patrick Chinnery
Dr David Samuels
The Distribution of Mitochondrial DNA Heteroplasmy Due to Random Genetic Drift
2008
Dr Angela Pyle
Professor Robert Taylor
Dr Steve Durham
Dr Andrew Schaefer
Dr David Samuels
et al.
Depletion of mitochondrial DNA in leucocytes harbouring the 3243A→G mtDNA mutation
2007
Dr Steve Durham
Dr David Samuels
Dr Lynsey Cree
Professor Patrick Chinnery
Normal levels of wild-type mitochondrial DNA maintain cytochrome c oxidase activity for two pathogenic mitochondrial DNA mutations but not for m.3243A→G
2007
Dr Steve Durham
Dr David Samuels
Professor Patrick Chinnery
Is selection required for the accumulation of somatic mitochondrial DNA mutations in post-mitotic cells?
2006
Dr David Samuels
Dr Robin Horton
Professor Patrick Chinnery
The power to detect disease associations with mitochondrial DNA haplogroups
2006
Professor Carlo Barenghi
Dr David Samuels
Scaling laws of vortex reconnections
2004
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