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Browsing publications by Professor Caroline Relton.

Newcastle AuthorsTitleYearFull text
Natassia Robinson
Dr Heather Brown
Professor Mark Pearce
Professor Caroline Relton
Dr Viviana Albani
et al.
Childhood DNA methylation as a marker of early life rapid weight gain and subsequent overweight2021
Professor Caroline Relton
Adversity exposure during sensitive periods predicts accelerated epigenetic aging in children2020
Dr Richard Howey
Dr So-Youn Shin
Professor Caroline Relton
Professor Heather Cordell
Bayesian network analysis incorporating genetic anchors complements conventional Mendelian randomization approaches for exploratory analysis of causal relationships in complex data2020
Professor Caroline Relton
Corrigendum to ‘Adversity exposure during sensitive periods predicts accelerated epigenetic aging in children’ [Psychoneuroendocrinology 113 March (2020) 104484] (Psychoneuroendocrinology (2020) 113, (S0306453019304755), (10.1016/j.psyneuen.2019.104484))2020
Ushma Shah
Professor Mark Walker
Professor Caroline Relton
Dr Hannah Elliott
Differential methylation of the type 2 diabetes susceptibility locus KCNQ1 is associated with insulin sensitivity and is predicted by CpG site specific genetic variation2019
Professor Caroline Relton
Is high vitamin B12 status a cause of lung cancer?2019
Professor Caroline Relton
Sensitive Periods for the Effect of Childhood Adversity on DNA Methylation: Results From a Prospective, Longitudinal Study2019
Professor Caroline Relton
Vitamin B6 catabolism and lung cancer risk: Results from the Lung Cancer Cohort Consortium (LC3)2019
Dr Kate Potter
Professor Caroline Relton
Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics2018
Professor Caroline Relton
Dr Paul Brennan
Impaired functional vitamin B6 status is associated with increased risk of lung cancer2018
Dr Kate Potter
Professor Anthony Moorman
Professor Caroline Relton
Professor John Mathers
Dr Gordon Strathdee
et al.
Maternal red blood cell folate and infant vitamin B12 status influence methylation of genes associated with childhood acute lymphoblastic leukaemia2018
Dr Frauke Becker
Professor Caroline Relton
Women’s preferences for alternative financial incentive schemes for breastfeeding: A discrete choice experiment2018
Professor Caroline Relton
Dr Paul Brennan
Circulating concentrations of biomarkers and metabolites related to vitamin status, one-carbon and the kynurenine pathways in US, Nordic, Asian, and Australian populations2017
Professor Caroline Relton
Circulating vitamin D in relation to cancer incidence and survival of the head and neck and oesophagus in the EPIC cohort2016
Professor Caroline Relton
DNA Methylation and BMI: Investigating Identified Methylation Sites at HIF3A in a Causal Framework2016
Jessica Timms
Professor Caroline Relton
Professor Judith Rankin
Dr Gordon Strathdee
Dr Jill McKay
et al.
DNA methylation as a potential mediator of environmental risks in the development of childhood acute lymphoblastic leukaemia2016
Professor Caroline Relton
Prenatal and early life influences on epigenetic age in children: a study of mother-offspring pairs from two cohort studies2016
Professor Caroline Relton
Systematic identification of genetic influences on methylation across the human life course2016
Professor Caroline Relton
A prospective study of one-carbon metabolism biomarkers and cancer of the head and neck and esophagus2015
Sanne van Otterdijk
Jean Norden
Professor Anne Dickinson
Professor Mark Pearce
Professor Caroline Relton
et al.
Aberrations in DNA methylation are detectable during remission of acute lymphoblastic leukemia and predict patient outcome2015
Dr So-Youn Shin
Professor Caroline Relton
Alcohol intake and cardiovascular risk factors: A Mendelian randomisation study2015
Dr So-Youn Shin
Professor Caroline Relton
Characterization of whole-genome autosomal differences of DNA methylation between men and women2015
Professor Caroline Relton
Professor Anil Wipat
Dr Keith Flanagan
Dr Allyson Lister
Data Resource Profile: Accessible Resource for Integrated Epigenomic Studies (ARIES)2015
Professor Caroline Relton
Longitudinal analysis of DNA methylation associated with birth weight and gestational age2015
Professor Caroline Relton
Maternal pre-pregnancy BMI and gestational weight gain, offspring DNA methylation and later offspring adiposity: findings from the Avon Longitudinal Study of Parents and Children2015
Professor Caroline Relton
Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis2015
Professor Caroline Relton
Prenatal Exposure to Maternal Cigarette Smoking and DNA Methylation: Epigenome-Wide Association in a Discovery Sample of Adolescents and Replication in an Independent Cohort at Birth through 17 Years of Age2015
Professor Caroline Relton
Prenatal exposure to maternal smoking and offspring DNA methylation across the lifecourse: findings from the Avon Longitudinal Study of Parents and Children (ALSPAC)2015
Professor Caroline Relton
Approaches for drawing causal inferences from epidemiological birth cohorts: A review2014
Professor Caroline Relton
Circulating biomarkers of tryptophan and the kynurenine pathway and lung cancer risk2014
Professor Caroline Relton
Differences in smoking associated DNA methylation patterns in South Asians and Europeans2014
Dr Eva Morales
Dr Alexandra Groom
Professor Caroline Relton
DNA methylation signatures in cord blood associated with maternal gestational weight gain: results from the ALSPAC cohort2014
Dr Kamil Sitarz
Dr Hannah Elliott
Betul Karaman
Professor Caroline Relton
Professor Patrick Chinnery
et al.
Valproic acid triggers increased mitochondrial biogenesis in POLG-deficient fibroblasts2014
Professor Caroline Relton
What is it about boys?2014
Dr Sara Brown
Dr Stephen Turner
Professor Caroline Relton
Professor Sir John Burn
Dr Simon Meggitt
et al.
Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects2013
Dr Hannah Elliott
Professor Caroline Relton
DNA methylation, cardio metabolic risk and type 2 diabetes in south Asians and Europeans2013
Dr Claire Wood
Dr Robert Tinnion
Dr Srinivasa Korada
Dr Timothy Cheetham
Professor Caroline Relton
et al.
Growth and metabolic outcome in adolescents born preterm (GROWMORE): follow-up protocol for the Newcastle preterm birth growth study (PTBGS)2013
Dr Jill McKay
Dr Alexandra Groom
Professor Dianne Ford
Lisa Coneyworth
Professor John Mathers
et al.
Influence of DNMT Genotype on Global and Site Specific DNA Methylation Patterns in Neonates and Pregnant Women2013
Addison Palomino Doza
Dr Ana Topf
Dr John O'Sullivan
Professor Caroline Relton
Professor Judith Goodship
et al.
Low-frequency intermediate penetrance variants in the ROCK1 gene predispose to Tetralogy of Fallot2013
Professor Judith Goodship
Dr Darroch Hall
Dr Ana Topf
Valentina Mamasoula
Dr Helen Griffin
et al.
A Common Variant in the PTPN11 Gene Contributes to the Risk of Tetralogy of Fallot2012
Dr Naweed Sattar
Professor Caroline Relton
Association Between Genetic Variants on Chromosome 15q25 Locus and Objective Measures of Tobacco Exposure2012
Valerie Turcot
Dr Alexandra Groom
Professor Mark Pearce
Dr Kate Potter
Professor Nicholas Embleton
et al.
Bioinformatic selection of putative epigenetically regulated loci associated with obesity using gene expression data2012
Professor Caroline Relton
Dr Alexandra Groom
Dr Daniel Swan
Professor Nicholas Embleton
Professor Mark Pearce
et al.
DNA methylation patterns in cord blood DNA and body size in childhood2012
Dr Kate Potter
Professor Caroline Relton
Epigenetic Epidemiology. Karin B. Michels (ed)2012
Professor Patrick Chinnery
Dr Hannah Elliott
Dr Gavin Hudson
Professor David Samuels
Professor Caroline Relton
et al.
Epigenetics, epidemiology and mitochondrial DNA diseases2012
Dr Jill McKay
Dr Alexandra Groom
Dr Kate Potter
Lisa Coneyworth
Professor Dianne Ford
et al.
Genetic and Non-Genetic Influences during Pregnancy on Infant Global and Site Specific DNA Methylation: Role for Folate Gene Variants and Vitamin B122012
Dr Kate Potter
Dr Jane Ng
Professor Caroline Relton
Genetic variation in the 15q25 nicotinic acetylcholine receptor gene cluster (CHRNA5-CHRNA3-CHRNB4) interacts with maternal self-reported smoking status during pregnancy to influence birth weight2012
Professor Mark Pearce
Dr Kate Potter
Laura Barrett
Professor Louise Parker
Professor John Mathers
et al.
Global LINE-1 DNA methylation is associated with blood glycaemic and lipid profiles2012
Professor Mark Pearce
Dr Kay Mann
Professor Caroline Relton
Emeritus Professor Roger Francis
Emeritus Professor Jimmy Steele CBE
et al.
How the Newcastle Thousand Families birth cohort study has contributed to the understanding of the impact of birth weight and early life socioeconomic position on disease in later life2012
Professor Caroline Relton
Is epidemiology ready for epigenetics?2012
Professor Caroline Relton
Mutations in genes encoding the glycine cleavage system predispose to neural tube defects in mice and humans2012
Dr Alexandra Groom
Professor Caroline Relton
People of the British Isles: preliminary analysis of genotypes and surnames in a UK-control population2012
Dr Alexandra Groom
Dr Kate Potter
Valerie Turcot
Professor Mark Pearce
Professor Nicholas Embleton
et al.
Postnatal Growth and DNA Methylation Are Associated With Differential Gene Expression of the TACSTD2 Gene and Childhood Fat Mass2012
Professor Caroline Relton
Prenatal nutrition, epigenetics and schizophrenia risk: can we test causal effects?2012
Laura Barrett
Professor Caroline Relton
The role of longitudinal cohort studies in epigenetic epidemiology: challenges and opportunities2012
Professor Caroline Relton
Two-step epigenetic Mendelian randomization: a strategy for establishing the causal role of epigenetic processes in pathways to disease2012
Professor Mark Pearce
Dr Alexandra Groom
Professor Caroline Relton
Professor Louise Parker
Emeritus Professor Roger Francis
et al.
Associations between sex hormones and bone mineral density and bone resorption in 50 year old men: The Newcastle thousand families study2011
Professor Mark Pearce
Dr Alexandra Groom
Professor Caroline Relton
Emeritus Professor Roger Francis
Birth weight and early socio-economic disadvantage as predictors of sex hormones and sex hormone binding globulin in men at age 49–51 years2011
Dr Kathryn Parkinson
Professor Mark Pearce
Professor Caroline Relton
Professor Ann Le Couteur
Professor Ashley Adamson
et al.
Cohort Profile: The Gateshead Millennium Study2011
Dr Jill McKay
Professor Dianne Ford
Professor Caroline Relton
Professor John Mathers
Consequences of Folate Depletion during Development for DNA Methylation and Gene Expression in the Fetal Mouse2011
Professor Caroline Relton
Dr Alexandra Groom
Dr Daniel Swan
Professor Nicholas Embleton
Professor Mark Pearce
et al.
DNA Methylation Patterns in Cord Blood DNA Predict Body Size in Childhood2011
Dr Alexandra Groom
Dr Hannah Elliott
Professor Nicholas Embleton
Professor Caroline Relton
Epigenetics and child health: basic principles2011
Dr Jill McKay
Dr Long Xie
Professor Caroline Relton
Professor Dianne Ford
Professor John Mathers
et al.
Folate Depletion during Development Causes Gene Expression Changes in Fetal and Adult Mouse Liver2011
Professor Caroline Relton
Genetic Polymorphisms in 15q25 and 19q13 Loci, Cotinine Levels, and Risk of Lung Cancer in EPIC2011
Dr Jill McKay
Professor Caroline Relton
Professor Dianne Ford
Professor John Mathers
Maternal folate supply and sex influence gene-specific DNA methylation in the fetal gut2011
Dr Alexandra Groom
Dr Kate Potter
Valerie Turcot
Professor Mark Pearce
Professor Nicholas Embleton
et al.
Postnatal Growth Is Associated with DNA Methylation and Childhood Adiposity: Using Genetic Variation to Infer the Direction of Causation2011
Professor Caroline Relton
Smoking, Secondhand Smoke, and Cotinine Levels in a Subset of EPIC Cohort2011
Professor Mark Pearce
Professor Caroline Relton
Dr Alexandra Groom
Emeritus Professor Roger Francis
A lifecourse study of bone resorption in men ages 49-51 years: The Newcastle Thousand Families cohort study2010
Professor Caroline Relton
Epigenetic Epidemiology of Common Complex Disease: Prospects for Prediction, Prevention, and Treatment2010
Professor Caroline Relton
Genetic selection? A study of individual variation in the enzymes of folate metabolism2010
Professor John Mathers
Dr Gordon Strathdee
Professor Caroline Relton
Induction of Epigenetic Alterations by Dietary and Other Environmental Factors2010
Dr Alison Sutherland
David Kim
Professor Caroline Relton
Professor John Hesketh
Polymorphisms in the selenoprotein S and 15-kDa selenoprotein genes are associated with altered susceptibility to colorectal cancer2010
Professor Caroline Relton
Dr Paul Brennan
Serum B vitamin levels and risk of lung cancer2010
Professor Caroline Relton
Dr Alexandra Groom
Dr Hannah Elliott
Dr Jill McKay
Professor Mark Pearce
et al.
Epigenetic Epidemiology: Evidence for the Role of Epigenetic Variation in Complex Disease2009
Dr Sara Brown
Professor Caroline Relton
Professor Heather Cordell
Professor Nick Reynolds
Filaggrin haploinsufficiency is highly penetrant and is associated with increased severity of eczema: further delineation of the skin phenotype in a prospective epidemiological study of 792 school children2009
Dr Tevfik Dorak
Professor Caroline Relton
Professor Louise Parker
Emeritus Professor Andy Hall
Hereditary Hemochromatosis Gene (HFE) Variants are Associated with Birth Weight and Childhood Leukemia Risk2009
Professor Mark Pearce
Professor Caroline Relton
Professor Louise Parker
Professor Nigel Unwin
Sex differences in the association between infant feeding and blood cholesterol in later life: the Newcastle thousand families cohort study at age 49-51 years2009
Dr Jill McKay
Professor Dianne Ford
Professor Caroline Relton
Professor John Mathers
Bioinformatic interrogation of expression array data to identify nutritionally regulated genes potentially modulated by DNA methylation2008
Dr Sara Brown
Professor Caroline Relton
Professor Sir John Burn
Professor Heather Cordell
Professor Nick Reynolds
et al.
Filaggrin mutations in atopic eczema: genotype-phenotype correlation2008
Adillah Binti Yusof
Professor Caroline Relton
Dr Ian Wilson
Professor Sir John Burn
Professor Nick Reynolds
et al.
Filaggrin null mutations and childhood atopic eczema: A population-based case-control study2008
Dr Sara Brown
Professor Caroline Relton
Dr Ian Wilson
Professor Sir John Burn
Professor Nick Reynolds
et al.
Filaggrin null mutations in mild-moderate atopic eczema: a population-based case-control study2008
Professor Mark Pearce
Professor Caroline Relton
Oxidative stress, telomere length and biomarkers of physical aging in a cohort aged 79 years from the 1932 Scottish Mental Survey2008
Dr Hannah Elliott
Dr David Samuels
James Eden
Professor Caroline Relton
Professor Patrick Chinnery
et al.
Pathogenic Mitochondrial DNA Mutations Are Common in the General Population2008
Dr Sara Brown
Professor Caroline Relton
Dr Simon Meggitt
Professor Nick Reynolds
Professor Heather Cordell
et al.
Prevalent and low-frequency null mutations in the filaggrin gene are associated with early-onset and persistent atopic eczema2008
Professor Mark Pearce
Professor Caroline Relton
Professor Nigel Unwin
Professor Ashley Adamson
The relation between diarrhoeal episodes in infancy and both blood pressure and sodium intake in later life: The Newcastle Thousand Families Study2008
Professor Caroline Relton
Professor Mark Pearce
Dr John O'Sullivan
The relationship between gestational age, systolic blood pressure and pulse pressure in children2008
Rachel MacKay
Professor Caroline Relton
Dr Tevfik Dorak
An HLA and leukaemia association study without HLA typing2007
Dr Alexandra Groom
Professor Caroline Relton
Dr Jill McKay
Laura Steedman
Professor John Mathers
et al.
DNA methylation status at the Igf2 locus in offspring of a mouse model of maternal diet-induced obesity2007
Dr Jill McKay
Professor Caroline Relton
Professor Dianne Ford
Professor John Mathers
Effects of dietary zinc supply during pregnancy on foetal liver DNA methylation of the insulin-like growth factor 2 (Igf2) gene in C57BL/J6 mice2007
Professor Caroline Relton
Genetic epidemiologic studies of preterm birth: guidelines for research2007
Professor Caroline Relton
Genetic epidemiologic studies of preterm birth: studies of disease or of "rescue by birth"?2007
Professor Caroline Relton
Dr Alexandra Groom
Dr Jill McKay
Professor Dianne Ford
Professor John Mathers
et al.
Polymorphic variation in DNA methyltransferase genes in relation to birth weight, smoking and folate status2007
Professor Caroline Relton
Dr Tevfik Dorak
Polymorphic variation in the haemochromatosis gene is associated with increased birth weight2007
Professor Caroline Relton
Reply2007
Professor Caroline Relton
Type 2 diabetes TCF7L2 risk genotypes alter birth weight: A study of 24,053 individuals2007
Professor Caroline Relton
DNA repair gene polymorphisms in relation to chromosome aberration frequencies in retired radiation workers2006
Professor Caroline Relton
Genotype profiles of loci encoding DNA repair enzymes in newborn and elderly populations: No evidence of association with longevity2006
Professor Caroline Relton
Gordon Taylor
Professor Patrick Chinnery
Emeritus Professor Doug Turnbull
Mitochondrial DNA mutations in individuals occupationally exposed to ionizing radiation2006
Professor Caroline Relton
Professor Mark Pearce
Dr John O'Sullivan
The relationship between gestational age and pulse pressure in children2006
Professor Caroline Relton
Professor Mark Pearce
Professor Sir John Burn
Professor Louise Parker
An investigation of folate-related genetic factors in the determination of birthweight2005
Professor Caroline Relton
DNA repair gene polymorphisms in relation to chromosome aberration frequencies in retired radiation workers2005
Professor Caroline Relton
Professor Mark Pearce
Professor Sir John Burn
Folate Status and Genetic Selection2005
Professor Caroline Relton
Professor Judith Rankin
Folic acid - the challenge of unplanned pregnancy and social deprivation2005
Professor Caroline Relton
Donna Hammal
Professor Judith Rankin
Professor Louise Parker
Folic acid supplementation and social deprivation2005
Professor Mark Pearce
Professor Nigel Unwin
Professor Caroline Relton
Emeritus Professor Sir George Sir George Alberti
Professor Louise Parker
et al.
Lifecourse determinants of fasting and post-challenge glucose at age 50 years: The Newcastle thousand families study2005
Professor Caroline Relton
Professor Mark Pearce
Professor Louise Parker
The influence of erythrocyte folate and serum vitamin B12 status on birth weight2005
Professor Caroline Relton
Donna Hammal
Professor Louise Parker
Professor Sir John Burn
DNA repair gene polymorphisms, pre-natal factors and the frequency of somatic mutations in the glycophorin-A gene among healthy newborns2004
Professor Caroline Relton
Professor Mark Pearce
James Laffey
Dr Sally Lynch
Professor Sir John Burn
et al.
Gene-gene interaction in folate-related genes and risk of neural tube defects in a UK population2004
Professor Caroline Relton
Professor Sir John Burn
Low erythrocyte folate status and polymorphic variation in folate-related genes are associated with risk of neural tube defect pregnancy2004
Professor Caroline Relton
Professor Sir John Burn
Thymidylate synthase repeat polymorphisms and risk of neural tube defects in a population from the northern United Kingdom2004
Professor Caroline Relton
Sumit Burkul
Folic acid - changes in women's knowledge2003
Professor Caroline Relton
Dr Sally Lynch
Genetic susceptibility to neural tube defect pregnancy varies with offspring phenotype2003
Professor Caroline Relton
Professor Andrew Fisher
Professor Sir John Burn
Polymorphisms of the DNA repair gene XRCC1 and the frequency of somatic mutations at the glycophorin A locus in newborns2002
Professor Caroline Relton
Polymorphisms of the DNA repair gene XRCC1 and the frequency of somatic mutations at the glycophorin A locus in newborns2002