Hanna Salmonowicz Dr James Chapman George Kelly Professor Laura Greaves Professor Derek Mann et al. | Apoptotic stress causes mtDNA release during senescence and drives the SASP | 2023 |
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Dr Katja Menger Dr James Chapman Mushtaq Khazeem Dr Dasha Deen John Casement et al. | Two type I topoisomerases maintain DNA topology in human mitochondria | 2022 |
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Dr Katja Menger Alejandro Rodriguez Luis Dr James Chapman Dr Thomas Nicholls
| Controlling the topology of mammalianmitochondrial DNA | 2021 |
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Dr Jack Leslie Dr Marie-Helene Ruchaud Amy Collins Leena Habiballa Dr Gabi Saretzki et al. | Neutrophils induce paracrine telomere dysfunction and senescence in ROS-dependent manner | 2021 |
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Emily Dookun Dr Anna Walaszczyk Dr Rachael Redgrave Dr Pawel Palmowski Dr Simon Tual-Chalot et al. | Clearance of senescent cells during cardiac ischemia–reperfusion injury improves recovery | 2020 |
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Dr James Chapman Dr Yi Ng Dr Thomas Nicholls
| The Maintenance of Mitochondrial DNA Integrity and Dynamics by Mitochondrial Membranes. | 2020 |
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Rhys Anderson Anthony Lagnado Damien Maggiorani Dr Anna Walaszczyk Emily Dookun et al. | Length‐independent telomere damage drives post‐mitotic cardiomyocyte senescence | 2019 |
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Dr James Chapman Dr Edward Fielder Dr Joao Passos
| Mitochondrial dysfunction and cell senescence: deciphering a complex relationship | 2019 |
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Clara Correia Melo Dr Jodie Birch Dr Edward Fielder Dr James Chapman Dr Anthony Lagnado et al. | Rapamycin improves healthspan but not inflammaging in nfkb1-/- mice | 2019 |
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Stella Victorelli Dr Anthony Lagnado Jessica Halim Dr James Chapman Dr Jodie Birch et al. | Senescent human melanocytes drive skin ageing via paracrine telomere dysfunction | 2019 |
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Dr James Chapman Dr Joao Passos
| Mitochondrial inner membrane permeabilisation enables mtDNA release during apoptosis | 2018 |
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