Dr Gabriele Saretzki Professor Alexander Burkle
| Senescence-like Phenotype After Chronic Exposure to Isoproterenol in Primary Quiescent Immune Cells | 2024 |
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Ragen Pfeiffer Alan Leake Dr Michelle Muller Emeritus Professor Thomas Kirkwood Professor Alexander Burkle et al. | A modified and automated version of the 'Fluorimetric Detection of Alkaline DNA Unwinding' method to quantify formation and repair of DNA strand breaks | 2009 |
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Yonghua Zhang Professor Alexander Burkle
| Genetic heterogeneity versus molecular analysis of prion susceptibility in neuroblasma N2a sublines | 2008 |
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Ragen Pfeiffer Dr Michelle Muller Alan Leake Emeritus Professor Thomas Kirkwood Professor Alexander Burkle et al. | An automated version of the fluorescence-detected alkaline DNA-unwinding (FADU) assay to measure DNA strand breaks and DNA repair | 2007 |
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Professor Doug Gray Professor Alexander Burkle
| SENS and the polarization of aging-related research | 2006 |
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Ragen Pfeiffer Dr Michelle Muller Alan Leake Emeritus Professor Thomas Kirkwood Professor Alexander Burkle et al. | An automated version of the fluorescence-detected alkaline DNA-unwinding (FADU) assay to measure DNA strand breaks and DNA repair | 2005 |
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Professor Alexander Burkle Dr Marie-Laure Muiras
| Expression of a dominant negative version of poly(ADP-ribose) polymerase-1 in basal skin keratinocytes of transgenic mice potentiates alkylationanduced in skin tumour formation | 2005 |
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Ragen Pfeiffer Alan Leake Professor Alexander Burkle
| L-selegiline potentiates cellular poly (ADP-ribose) formation induced by DNA damage | 2004 |
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Professor Alexander Burkle Dr Marie-Laure Muiras
| Poly(ADP-ribosyl)ation and aging | 2004 |
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Ragen Pfeiffer Alan Leake Professor Alexander Burkle
| L-selegiline potentiates the cellular poly(ADP-ribosyl)ation response to ionizing radiation | 2003 |
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Professor Alexander Burkle Emeritus Professor Thomas Kirkwood
| Poly(ADP-ribose) polymerase-1 is a survival factor for radiation-exposed intestinal epithelial stem cells in vivo | 2003 |
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Yonghua Zhang Professor Alexander Burkle
| Up-regulation of cathepsin B and cathepsin L activities in scrapie-infected mouse Neuro2a cells | 2003 |
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Professor Alexander Burkle
| In memoriam - Bernard Strehler - genomic instability in ageing: a persistent challenge | 2002 |
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Professor Alexander Burkle
| Increase in de novo HBV DNA integrations in response to oxidative DNA damage or inhibition of poly(ADP-ribosyl)ation | 2002 |
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Professor Alexander Burkle
| In-situ analysis of cellular poly(ADP-ribose) production in scrapie-infected mouse neuroblastoma cells | 2002 |
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Professor Alexander Burkle
| Interference by toxic metal ions with DNA repair processes and cell cycle control: Molecular mechanisms | 2002 |
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Professor Alexander Burkle
| Interference by toxic metal ions with zinc-dependent proteins involved in maintaining genomic stability | 2002 |
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Professor Alexander Burkle
| L-selegiline potentiates cellular poly(ADP-ribose) formation induced by DNA damage | 2002 |
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Professor Alexander Burkle Alan Leake Dr Marie-Laure Muiras Ragen Pfeiffer
| Poly(ADP-ribose) polymerase-1, DNA repair and mammalian longevity | 2002 |
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Professor Alexander Burkle
| Poly(ADP-ribosyl)ation, genomic instability and mammalian longevity | 2002 |
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Professor Alexander Burkle
| Reduced poly(ADP-ribosyl)ation in lymphocytes of laryngeal cancer patients: Results of a case-control study | 2002 |
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Professor Alexander Burkle
| Role of poly(ADP-ribosyl)ation in DNA-PKcs-independent V(D)J recombination | 2002 |
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Professor Alexander Burkle
| Mechanisms of ageing | 2001 |
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Professor Alexander Burkle
| PARP-1: a regulator of genomic stability linked with mammalian longevity | 2001 |
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Professor Alexander Burkle
| Physiology and pathophysiology of poly(ADP-ribosyl)ation | 2001 |
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Professor Alexander Burkle
| Poly(APD-ribosyl)ation, a DNA damage-driven protein modification and regulator of genomic instability | 2001 |
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Professor Thomas von Zglinicki Professor Alexander Burkle Emeritus Professor Thomas Kirkwood
| Stress, DNA damage and ageing - An integrative approach | 2001 |
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Professor Alexander Burkle
| Comparative characterisation of poly(ADP-ribose) polymerase-1 from two mammalian species with different life span | 2000 |
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Professor Alexander Burkle
| Negative regulation of alkylation-induced sister-chromatid exchange by poly(ADP-ribose) polymerase-1 activity | 2000 |
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Professor Alexander Burkle Dr Marie-Laure Muiras
| New polymorphisms in the human poly(ADP-ribose) polymerase-1 coding sequence: Lack of association with longevity or with increased cellular poly(ADP-ribosyl)ation capacity | 2000 |
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Professor Alexander Burkle
| Poly(ADP-ribosyl)ation, genomic instability, and longevity | 2000 |
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Professor Alexander Burkle
| Poly(ADP-ribosyl)ation, genomic instability, and longevity | 2000 |
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Professor Alexander Burkle
| Poly(ADP-ribosyl)ation: A posttranslational protein modification linked with genome protection and mammalian longevity | 2000 |
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Professor Alexander Burkle
| Quantitative assessment of bleomycin-induced poly(ADP-ribosyl)ation in human lymphocytes by immunofluorescence and image analysis | 2000 |
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Professor Alexander Burkle
| Detection of poly(ADP-ribose) synthesis in Drosophila testes upon gamma-irradiation | 1999 |
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Professor Alexander Burkle
| Overexpression of dominant negative PARP interferes with tumor formation of HeLa cells in nude mice: evidence for increased tumor cell apoptosis in vivo | 1999 |
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Professor Alexander Burkle
| Poly(ADP-ribose) immunostaining to detect apoptosis induced by a neurotoxic fragment of prion protein | 1999 |
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Ragen Pfeiffer Professor Alexander Burkle
| Quantitative nonisotopic immuno-dot-blot method for the assessment of cellular poly(ADP-ribosyl)ation capacity | 1999 |
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Professor Alexander Burkle
| Reactive oxygen species participate in mdr1b mRNA and P-glycoprotein overexpression in primary rat hepatocyte cultures | 1999 |
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Professor Alexander Burkle
| Selective loss of poly(ADP-ribose) and the 85-kDa fragment of poly(ADP-ribose) polymerase in nucleoli during alkylation-induced apoptosis of HeLa cells | 1999 |
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Professor Alexander Burkle
| Trans-dominant inhibition of poly(ADP-ribosyl)ation potentiates alkylation-induced shuttle-vector mutagenesis in Chinese hamster cells | 1999 |
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