Publications by Professor Alexander Burkle - ePrints

Browsing publications by Professor Alexander Burkle.

Newcastle Authors	Title	Year
Ragen Pfeiffer Alan Leake Dr Michelle Muller Emeritus Professor Thomas Kirkwood Professor Alexander Burkle et al.	A modified and automated version of the 'Fluorimetric Detection of Alkaline DNA Unwinding' method to quantify formation and repair of DNA strand breaks	2009
Yonghua Zhang Professor Alexander Burkle	Genetic heterogeneity versus molecular analysis of prion susceptibility in neuroblasma N2a sublines	2008
Ragen Pfeiffer Dr Michelle Muller Alan Leake Emeritus Professor Thomas Kirkwood Professor Alexander Burkle et al.	An automated version of the fluorescence-detected alkaline DNA-unwinding (FADU) assay to measure DNA strand breaks and DNA repair	2007
Professor Doug Gray Professor Alexander Burkle	SENS and the polarization of aging-related research	2006
Ragen Pfeiffer Dr Michelle Muller Alan Leake Emeritus Professor Thomas Kirkwood Professor Alexander Burkle et al.	An automated version of the fluorescence-detected alkaline DNA-unwinding (FADU) assay to measure DNA strand breaks and DNA repair	2005
Professor Alexander Burkle Dr Marie-Laure Muiras	Expression of a dominant negative version of poly(ADP-ribose) polymerase-1 in basal skin keratinocytes of transgenic mice potentiates alkylationanduced in skin tumour formation	2005
Ragen Pfeiffer Alan Leake Professor Alexander Burkle	L-selegiline potentiates cellular poly (ADP-ribose) formation induced by DNA damage	2004
Professor Alexander Burkle Dr Marie-Laure Muiras	Poly(ADP-ribosyl)ation and aging	2004
Ragen Pfeiffer Alan Leake Professor Alexander Burkle	L-selegiline potentiates the cellular poly(ADP-ribosyl)ation response to ionizing radiation	2003
Professor Alexander Burkle Emeritus Professor Thomas Kirkwood	Poly(ADP-ribose) polymerase-1 is a survival factor for radiation-exposed intestinal epithelial stem cells in vivo	2003
Yonghua Zhang Professor Alexander Burkle	Up-regulation of cathepsin B and cathepsin L activities in scrapie-infected mouse Neuro2a cells	2003
Professor Alexander Burkle	In memoriam - Bernard Strehler - genomic instability in ageing: a persistent challenge	2002
Professor Alexander Burkle	Increase in de novo HBV DNA integrations in response to oxidative DNA damage or inhibition of poly(ADP-ribosyl)ation	2002
Professor Alexander Burkle	In-situ analysis of cellular poly(ADP-ribose) production in scrapie-infected mouse neuroblastoma cells	2002
Professor Alexander Burkle	Interference by toxic metal ions with DNA repair processes and cell cycle control: Molecular mechanisms	2002
Professor Alexander Burkle	Interference by toxic metal ions with zinc-dependent proteins involved in maintaining genomic stability	2002
Professor Alexander Burkle	L-selegiline potentiates cellular poly(ADP-ribose) formation induced by DNA damage	2002
Professor Alexander Burkle Alan Leake Dr Marie-Laure Muiras Ragen Pfeiffer	Poly(ADP-ribose) polymerase-1, DNA repair and mammalian longevity	2002
Professor Alexander Burkle	Poly(ADP-ribosyl)ation, genomic instability and mammalian longevity	2002
Professor Alexander Burkle	Reduced poly(ADP-ribosyl)ation in lymphocytes of laryngeal cancer patients: Results of a case-control study	2002
Professor Alexander Burkle	Role of poly(ADP-ribosyl)ation in DNA-PKcs-independent V(D)J recombination	2002
Professor Alexander Burkle	Mechanisms of ageing	2001
Professor Alexander Burkle	PARP-1: a regulator of genomic stability linked with mammalian longevity	2001
Professor Alexander Burkle	Physiology and pathophysiology of poly(ADP-ribosyl)ation	2001
Professor Alexander Burkle	Poly(APD-ribosyl)ation, a DNA damage-driven protein modification and regulator of genomic instability	2001
Professor Thomas von Zglinicki Professor Alexander Burkle Emeritus Professor Thomas Kirkwood	Stress, DNA damage and ageing - An integrative approach	2001
Professor Alexander Burkle	Comparative characterisation of poly(ADP-ribose) polymerase-1 from two mammalian species with different life span	2000
Professor Alexander Burkle	Negative regulation of alkylation-induced sister-chromatid exchange by poly(ADP-ribose) polymerase-1 activity	2000
Professor Alexander Burkle Dr Marie-Laure Muiras	New polymorphisms in the human poly(ADP-ribose) polymerase-1 coding sequence: Lack of association with longevity or with increased cellular poly(ADP-ribosyl)ation capacity	2000
Professor Alexander Burkle	Poly(ADP-ribosyl)ation, genomic instability, and longevity	2000
Professor Alexander Burkle	Poly(ADP-ribosyl)ation, genomic instability, and longevity	2000
Professor Alexander Burkle	Poly(ADP-ribosyl)ation: A posttranslational protein modification linked with genome protection and mammalian longevity	2000
Professor Alexander Burkle	Quantitative assessment of bleomycin-induced poly(ADP-ribosyl)ation in human lymphocytes by immunofluorescence and image analysis	2000
Professor Alexander Burkle	Detection of poly(ADP-ribose) synthesis in Drosophila testes upon gamma-irradiation	1999
Professor Alexander Burkle	Overexpression of dominant negative PARP interferes with tumor formation of HeLa cells in nude mice: evidence for increased tumor cell apoptosis in vivo	1999
Professor Alexander Burkle	Poly(ADP-ribose) immunostaining to detect apoptosis induced by a neurotoxic fragment of prion protein	1999
Ragen Pfeiffer Professor Alexander Burkle	Quantitative nonisotopic immuno-dot-blot method for the assessment of cellular poly(ADP-ribosyl)ation capacity	1999
Professor Alexander Burkle	Reactive oxygen species participate in mdr1b mRNA and P-glycoprotein overexpression in primary rat hepatocyte cultures	1999
Professor Alexander Burkle	Selective loss of poly(ADP-ribose) and the 85-kDa fragment of poly(ADP-ribose) polymerase in nucleoli during alkylation-induced apoptosis of HeLa cells	1999
Professor Alexander Burkle	Trans-dominant inhibition of poly(ADP-ribosyl)ation potentiates alkylation-induced shuttle-vector mutagenesis in Chinese hamster cells	1999