Publications by Dr Gordon Strathdee - ePrints

Browsing publications by Dr Gordon Strathdee.

Newcastle Authors	Title	Year
John Casement Dr Gordon Strathdee Professor Mark Pearce	Epigenome-wide analysis across the development span of pediatric acute lymphoblastic leukemia: backtracking to birth	2024
Chalermsin Permtermsin - Lalchungnunga Dr Sirintra Nakjang John Casement Dr Laura Ogle et al.	Identification of TIAM1 as a Potential Synthetic-Lethal-like Gene in a Defined Subset of Hepatocellular Carcinoma	2023
Natassia Robinson John Casement Professor Roderick Skinner Professor Linda Sharp Dr Jill McKay et al.	Anti-cancer therapy is associated with long-term epigenomic changes in childhood cancer survivors	2022
Wen Hao Professor Deborah Tweddle Dr Ed Schwalbe Dr Gordon Strathdee	Genome wide DNA methylation analysis identifies novel molecular subgroups and predicts survival in neuroblastoma	2022
Dr Timothy Barrow Dr Elaine Willmore Dr Gordon Strathdee Dr Hyang-Min Byun	Analysis of retrotransposon subfamily DNA methylation reveals novel early epigenetic changes in chronic lymphocytic leukaemia	2021
Dr Timothy Barrow Dr Sirintra Nakjang Kateryna Bilotkach Dr Laura Woodhouse Gesa Junge et al.	Epigenome-wide analysis reveals functional modulators of drug sensitivity and post-treatment survival in chronic lymphocytic leukaemia	2021
Dr Wei-Yu Lin Dr Sarah Fordham Dr Nicola Sunter Dr Claire Elstob Dr Thahira Rahman et al.	Genome-wide association study identifies risk loci for progressive chronic lymphocytic leukemia	2021
Dr Ed Schwalbe - Lalchungnunga Dr Timothy Barrow Dr Gordon Strathdee	Integration of genome-level data to allow identification of subtype-specific vulnerability genes as novel therapeutic targets	2021
Professor Judith Rankin Dr Gordon Strathdee Dr Jill McKay	Exploring a potential mechanistic role of DNA methylation in the relationship between in utero and post-natal environmental exposures and risk of childhood acute lymphoblastic leukaemia	2019
Dr Kate Potter Professor Anthony Moorman Professor Caroline Relton Professor John Mathers Dr Gordon Strathdee et al.	Maternal red blood cell folate and infant vitamin B12 status influence methylation of genes associated with childhood acute lymphoblastic leukaemia	2018
Jessica Timms Professor Caroline Relton Professor Judith Rankin Dr Gordon Strathdee Dr Jill McKay et al.	DNA methylation as a potential mediator of environmental risks in the development of childhood acute lymphoblastic leukaemia	2016
Dr Timothy Barrow Dr Laura Woodhouse Gesa Junge Dr Susan Tudhope Dr Jonathan Wallis et al.	The Role of HOXA4 in Chronic Lymphocytic Leukaemia Progression and Response to Therapy	2016
Sanne van Otterdijk Jean Norden Professor Anne Dickinson Professor Mark Pearce Professor Caroline Relton et al.	Aberrations in DNA methylation are detectable during remission of acute lymphoblastic leukemia and predict patient outcome	2015
Dr Chris Smart Dr Gordon Strathdee Dr Stuart Watson Professor Hamish McAllister-Williams	Early life trauma, depression and the glucocorticoid receptor gene - an epigenetic perspective	2015
Dr Al Gabriel Fadhel Alsaid Naji Dr Ed Schwalbe Dr Sirintra Nakjang Dr Simon Cockell et al.	Epigenetic landscape correlates with genetic subtype but does not predict outcome in childhood acute lymphoblastic leukemia	2015
Dr Joanna Collerton Hannah Gautrey Sanne van Otterdijk Dr Karen Davies Dr Carmen Martin-Ruiz et al.	Acquisition of aberrant DNA methylation is associated with frailty in the very old: findings from the Newcastle 85+Study	2014
Hannah Gautrey Sanne van Otterdijk Professor Heather Cordell Professor John Mathers Dr Gordon Strathdee et al.	DNA methylation abnormalities at gene promoters are extensive and variable in the elderly and phenocopy cancer cells	2014
Fadhel Alsaid Naji Dr Vikki Rand Professor Anthony Moorman Dr Ed Schwalbe Dr Amir Enshaei et al.	Investigation of methylation based biomarkers for prediction of relapse in good prognostic cytogenetic subgroups of childhood acute lymphoblastic leukaemia	2014
Sanne van Otterdijk Professor John Mathers Dr Gordon Strathdee	Do age-related changes in DNA methylation play a role in the development of age-related diseases?	2013
Shabnam Thathia Stuart Ferguson Hannah Gautrey Sanne Van Otterdijk Dr Vikki Rand et al.	Epigenetic inactivation of TWIST2 in acute lymphoblastic leukemia modulates proliferation, cell survival and chemosensitivity	2012
Dr Tryfonia Mainou-Fowler Dr Gordon Strathdee	Methylation markers identify high risk patients in IGHV mutated chronic lymphocytic leukemia	2011
Dr Gordon Strathdee	Methylation markers in the clinical management of leukemia patients – Wave of the future or damp squib?	2011
Stuart Ferguson Hannah Gautrey Dr Gordon Strathdee	The Dual Role of HLXB9 in Leukemia	2011
Dr Gordon Strathdee Stuart Ferguson	DNA methylation does not regulate JUNB expression in CML: Comment on "Downregulation of JUNB mRNA expression in advanced phase chronic myelogenous leukemia" by Hoshino et al. [Leuk. Res. 33 (2009) 1361-1366]	2010
Professor John Mathers Dr Gordon Strathdee Professor Caroline Relton	Induction of Epigenetic Alterations by Dietary and Other Environmental Factors	2010
Dr Gordon Strathdee	HOXA5 is targeted by cell-type-specific CpG island methylation in normal cells and during the development of acute myeloid leukaemia	2007
Dr Gordon Strathdee	Epigenetic markers and response to chemotherapy in cancer	2007
Dr Gordon Strathdee Professor Anne Dickinson	HOX genes - Candidate tumor suppressor genes in adult, and childhood leukemia.	2007
Dr Gordon Strathdee Professor Anne Dickinson	HOX genes are a major target for epigenetic mis-regulation in adult and childhood leukaemia	2007
Dr Gordon Strathdee Professor Anne Dickinson	Inactivation of HOXA genes by hypermethylation in myeloid and lymphoid malignancy is frequent and associated with poor prognosis	2007
Dr Gordon Strathdee Dr Laura Mackay	Phase I and pharmacodynamic trial of the DNA methyltransferase inhibitor decitabine and carboplatin in solid tumors.	2007
Dr Janet Lindsey Dr Meryl Lusher Dr Gordon Strathdee Robert Brown Dr Richard Gilbertson et al.	Epigenetic inactivation of MCJ (DNAJD1) in malignant paediatric brain tumours	2006
Dr Janet Lindsey Dr Meryl Lusher Dr Gordon Strathdee Dr Richard Gilbertson Professor Simon Bailey et al.	Epigenetic inactivation of MCJ (DNAJD1) in malignant paediatric brain tumours	2006
Dr Gordon Strathdee	Promoter hypermethylation silences expression of the HoxA4 gene and correlates with IgVh mutational status in CLL	2006
Dr Gordon Strathdee	CpG island methylation of DNA damage response genes in advanced ovarian cancer	2005
Dr Gordon Strathdee	Demethylation of the MCJ gene in stage III/IV epithelial ovarian cancer and response to chemotherapy	2005
Dr Gordon Strathdee	Bioscience 2004	2004
Dr Gordon Strathdee Dr Barry Davies	Cell type-specific methylation of an intronic CpG island controls expression of the MCJ gene	2004
Dr Gordon Strathdee	Control of gene expression by CpG island methylation in normal cells	2004
Dr Gordon Strathdee	CpG-island methylation and epigenetic control of resistance to chemotherapy	2004
Dr Gordon Strathdee	Epigenetic silencing mediated by CpG island methylation: potential as a therapeutic target and as a biomarker	2004
Dr Gordon Strathdee	Aberrant DNA methylation in cancer: potential clinical interventions	2002
Dr Gordon Strathdee	Epigenetic cancer therapies: DNA methyltransferase inhibitors	2002
Dr Gordon Strathdee	Epigenetic versus genetic alterations in the inactivation of E-cadherin	2002
Dr Gordon Strathdee	Epigenomics and epigenetic therapy of cancer	2002
Dr Gordon Strathdee	Methylation microarray analysis of late-stage ovarian carcinomas distinguishes progression-free survival in patients and identifies candidate epigenetic markers	2002
Dr Gordon Strathdee	A role for mismatch repair in control of DNA ploidy following DNA damage	2001
Dr Gordon Strathdee	Primary Ovarian Carcinomas Display Multiple Methylator Phenotypes Involving Known Tumor Suppressor Genes	2001
Dr Gordon Strathdee Julieann Sludden	Reversal of drug resistance in human tumor xenografts by 2'-deoxy-5-azacytidine-induced demethylation of the hMLH1 gene promoter	2000
Dr Gordon Strathdee	A role for methylation of the hMLH1 promoter in loss of hMLH1 expression and drug resistance in ovarian cancer	1999
Dr Gordon Strathdee	Analysis of the CAVEOLIN-1 gene at human chromosome 7q31.1 in primary tumours and tumour-derived cell lines	1999