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Browsing publications by Dr Gordon Strathdee.

Newcastle AuthorsTitleYearFull text
Natassia Robinson
John Casement
Professor Roderick Skinner
Professor Linda Sharp
Dr Jill McKay
et al.
Anti-cancer therapy is associated with long-term epigenomic changes in childhood cancer survivors2022
Dr Timothy Barrow
Dr Elaine Willmore
Dr Gordon Strathdee
Dr Hyang-Min Byun
Analysis of retrotransposon subfamily DNA methylation reveals novel early epigenetic changes in chronic lymphocytic leukaemia2021
Dr Timothy Barrow
Dr Sirintra Nakjang
Kateryna Bilotkach
Dr Laura Woodhouse
Gesa Junge
et al.
Epigenome-wide analysis reveals functional modulators of drug sensitivity and post-treatment survival in chronic lymphocytic leukaemia2021
Dr Wei-Yu Lin
Dr Sarah Fordham
Dr Nicola Sunter
Dr Claire Elstob
Dr Thahira Rahman
et al.
Genome-wide association study identifies risk loci for progressive chronic lymphocytic leukemia2021
Dr Ed Schwalbe
- Lalchungnunga
Dr Timothy Barrow
Dr Gordon Strathdee
Integration of genome-level data to allow identification of subtype-specific vulnerability genes as novel therapeutic targets2021
Professor Judith Rankin
Dr Gordon Strathdee
Dr Jill McKay
Exploring a potential mechanistic role of DNA methylation in the relationship between in utero and post-natal environmental exposures and risk of childhood acute lymphoblastic leukaemia2019
Dr Kate Potter
Professor Anthony Moorman
Professor Caroline Relton
Professor John Mathers
Dr Gordon Strathdee
et al.
Maternal red blood cell folate and infant vitamin B12 status influence methylation of genes associated with childhood acute lymphoblastic leukaemia2018
Jessica Timms
Professor Caroline Relton
Professor Judith Rankin
Dr Gordon Strathdee
Dr Jill McKay
et al.
DNA methylation as a potential mediator of environmental risks in the development of childhood acute lymphoblastic leukaemia2016
Dr Timothy Barrow
Dr Laura Woodhouse
Gesa Junge
Dr Susan Tudhope
Dr Jonathan Wallis
et al.
The Role of HOXA4 in Chronic Lymphocytic Leukaemia Progression and Response to Therapy2016
Sanne van Otterdijk
Jean Norden
Professor Anne Dickinson
Professor Mark Pearce
Professor Caroline Relton
et al.
Aberrations in DNA methylation are detectable during remission of acute lymphoblastic leukemia and predict patient outcome2015
Dr Chris Smart
Dr Gordon Strathdee
Dr Stuart Watson
Professor Hamish McAllister-Williams
Early life trauma, depression and the glucocorticoid receptor gene - an epigenetic perspective2015
Dr Al Gabriel
Fadhel Alsaid Naji
Dr Ed Schwalbe
Dr Sirintra Nakjang
Dr Simon Cockell
et al.
Epigenetic landscape correlates with genetic subtype but does not predict outcome in childhood acute lymphoblastic leukemia2015
Dr Joanna Collerton
Hannah Gautrey
Sanne van Otterdijk
Dr Karen Davies
Dr Carmen Martin-Ruiz
et al.
Acquisition of aberrant DNA methylation is associated with frailty in the very old: findings from the Newcastle 85+Study2014
Hannah Gautrey
Sanne van Otterdijk
Professor Heather Cordell
Professor John Mathers
Dr Gordon Strathdee
et al.
DNA methylation abnormalities at gene promoters are extensive and variable in the elderly and phenocopy cancer cells2014
Fadhel Alsaid Naji
Dr Vikki Rand
Professor Anthony Moorman
Dr Ed Schwalbe
Dr Amir Enshaei
et al.
Investigation of methylation based biomarkers for prediction of relapse in good prognostic cytogenetic subgroups of childhood acute lymphoblastic leukaemia2014
Sanne van Otterdijk
Professor John Mathers
Dr Gordon Strathdee
Do age-related changes in DNA methylation play a role in the development of age-related diseases?2013
Shabnam Thathia
Stuart Ferguson
Hannah Gautrey
Sanne Van Otterdijk
Dr Vikki Rand
et al.
Epigenetic inactivation of TWIST2 in acute lymphoblastic leukemia modulates proliferation, cell survival and chemosensitivity2012
Dr Tryfonia Mainou-Fowler
Dr Gordon Strathdee
Methylation markers identify high risk patients in IGHV mutated chronic lymphocytic leukemia2011
Dr Gordon Strathdee
Methylation markers in the clinical management of leukemia patients – Wave of the future or damp squib?2011
Stuart Ferguson
Hannah Gautrey
Dr Gordon Strathdee
The Dual Role of HLXB9 in Leukemia2011
Dr Gordon Strathdee
Stuart Ferguson
DNA methylation does not regulate JUNB expression in CML: Comment on "Downregulation of JUNB mRNA expression in advanced phase chronic myelogenous leukemia" by Hoshino et al. [Leuk. Res. 33 (2009) 1361-1366]2010
Professor John Mathers
Dr Gordon Strathdee
Professor Caroline Relton
Induction of Epigenetic Alterations by Dietary and Other Environmental Factors2010
Dr Gordon Strathdee
HOXA5 is targeted by cell-type-specific CpG island methylation in normal cells and during the development of acute myeloid leukaemia2007
Dr Gordon Strathdee
Epigenetic markers and response to chemotherapy in cancer2007
Dr Gordon Strathdee
Professor Anne Dickinson
HOX genes - Candidate tumor suppressor genes in adult, and childhood leukemia.2007
Dr Gordon Strathdee
Professor Anne Dickinson
HOX genes are a major target for epigenetic mis-regulation in adult and childhood leukaemia2007
Dr Gordon Strathdee
Professor Anne Dickinson
Inactivation of HOXA genes by hypermethylation in myeloid and lymphoid malignancy is frequent and associated with poor prognosis2007
Dr Gordon Strathdee
Dr Laura Mackay
Phase I and pharmacodynamic trial of the DNA methyltransferase inhibitor decitabine and carboplatin in solid tumors.2007
Dr Janet Lindsey
Dr Meryl Lusher
Dr Gordon Strathdee
Robert Brown
Dr Richard Gilbertson
et al.
Epigenetic inactivation of MCJ (DNAJD1) in malignant paediatric brain tumours2006
Dr Janet Lindsey
Dr Meryl Lusher
Dr Gordon Strathdee
Dr Richard Gilbertson
Professor Simon Bailey
et al.
Epigenetic inactivation of MCJ (DNAJD1) in malignant paediatric brain tumours2006
Dr Gordon Strathdee
Promoter hypermethylation silences expression of the HoxA4 gene and correlates with IgVh mutational status in CLL2006
Dr Gordon Strathdee
CpG island methylation of DNA damage response genes in advanced ovarian cancer2005
Dr Gordon Strathdee
Demethylation of the MCJ gene in stage III/IV epithelial ovarian cancer and response to chemotherapy2005
Dr Gordon Strathdee
Bioscience 20042004
Dr Gordon Strathdee
Dr Barry Davies
Cell type-specific methylation of an intronic CpG island controls expression of the MCJ gene2004
Dr Gordon Strathdee
Control of gene expression by CpG island methylation in normal cells2004
Dr Gordon Strathdee
CpG-island methylation and epigenetic control of resistance to chemotherapy2004
Dr Gordon Strathdee
Epigenetic silencing mediated by CpG island methylation: potential as a therapeutic target and as a biomarker2004
Dr Gordon Strathdee
Aberrant DNA methylation in cancer: potential clinical interventions2002
Dr Gordon Strathdee
Epigenetic cancer therapies: DNA methyltransferase inhibitors2002
Dr Gordon Strathdee
Epigenetic versus genetic alterations in the inactivation of E-cadherin2002
Dr Gordon Strathdee
Epigenomics and epigenetic therapy of cancer2002
Dr Gordon Strathdee
Methylation microarray analysis of late-stage ovarian carcinomas distinguishes progression-free survival in patients and identifies candidate epigenetic markers2002
Dr Gordon Strathdee
A role for mismatch repair in control of DNA ploidy following DNA damage2001
Dr Gordon Strathdee
Primary Ovarian Carcinomas Display Multiple Methylator Phenotypes Involving Known Tumor Suppressor Genes2001
Dr Gordon Strathdee
Julieann Sludden
Reversal of drug resistance in human tumor xenografts by 2'-deoxy-5-azacytidine-induced demethylation of the hMLH1 gene promoter2000
Dr Gordon Strathdee
A role for methylation of the hMLH1 promoter in loss of hMLH1 expression and drug resistance in ovarian cancer1999
Dr Gordon Strathdee
Analysis of the CAVEOLIN-1 gene at human chromosome 7q31.1 in primary tumours and tumour-derived cell lines1999