Publications by Mike Cole - ePrints

Browsing publications by Mike Cole.

Newcastle Authors	Title	Year
Dr Faye Wolstenhulme Irena Bibby Mike Cole Lydia Grixti Dr Naomi McGregor et al.	Graves-PCD: protocol for a randomised, dose-finding, adaptive trial of the plasma cell-depleting agent daratumumab in severe Graves' disease	2024
Professor Timothy Cheetham Mike Cole Dr Mario Abinun Dr Sonya Carnell Jon Prichard et al.	Adjuvant Rituximab-Exploratory Trial in Young People With Graves Disease	2022
Dr Claire Wood Mike Cole Ruth Wood Professor Simon Pearce Professor Timothy Cheetham et al.	Initial response of young people with thyrotoxicosis to block and replace or dose titration thionamide	2022
Dr Arthur Pratt Dr Stefan Siebert Mike Cole Dr Deborah Stocken Amy Cranston et al.	Targeting synovial fibroblast proliferation in rheumatoid arthritis (TRAFIC): an open-label, dose-finding, phase 1b trial	2021
Mike Cole Professor Fai Ng Dr Stefan Siebert Dr Arthur Pratt Professor John Isaacs et al.	TRAFIC: statistical design and analysis plan for a pragmatic early phase 1/2 Bayesian adaptive dose escalation trial in rheumatoid arthritis	2021
Dr Claire Wood Mike Cole Ruth Wood Professor John Matthews Professor Simon Pearce et al.	Randomised trial of block and replace vs dose titration thionamide in young people with thyrotoxicosis	2020
Dr Stefan Siebert Dr Arthur Pratt Dr Deborah Stocken Dr Miranda Patterson Amy Cranston et al.	Targeting the rheumatoid arthritis synovial fibroblast via cyclin dependent kinase inhibition: An early phase trial	2020
Mike Cole Dr Ann Marie Hynes Denise Howel Dr Lesley Hall Dr Mario Abinun et al.	Adjuvant rituximab, a potential treatment for the young patient with Graves’ hyperthyroidism (RiGD): study protocol for a single-arm, single-stage, phase II trial	2019
Professor Jeremy Parr Dr Emma Todhunter Professor Lindsay Pennington Dr Deborah Stocken Dr Jill Cadwgan et al.	Drooling Reduction Intervention randomised trial (DRI): comparing the efficacy and acceptability of hyoscine patches and glycopyrronium liquid on drooling in children with neurodisability	2018
Professor Vinidh Paleri Dr Joanne Patterson Dr Deborah Stocken Mike Cole Professor Luke Vale et al.	A feasibility study incorporating a pilot randomised controlled trial of oral feeding plus pre-treatment gastrostomy tube versus oral feeding plus as-needed nasogastric tube feeding in patients undergoing chemoradiation for head and neck cancer (TUBE trial): study protocol	2016
Dr Sarah Fordham Mike Cole Professor Julie Irving Professor James Allan	Cytarabine preferentially induces mutation at specific sequences in the genome which are identifiable in relapsed acute myeloid leukaemia	2015
Dr Ashleigh Herriott Dr Susan Tudhope Gesa Junge Natalie Rodrigues Dr Miranda Patterson et al.	PARP1 expression, activity and ex vivo sensitivity to the PARP inhibitor, talazoparib (BMN 673), in Chronic Lymphocytic Leukaemia	2015
Dr Sarah Fordham Mike Cole Professor Julie Irving Professor James Allan	Cytarabine leaves a mutational fingerprint in relapsing leukemia	2014
Dr Jess Dyson Dr Dipanker Chattopadhyay Rajiv Lochan Jayadeva Dr Imran Patanwala Mike Cole et al.	Hepatocellular cancer: The impact of obesity, type 2 diabetes and a multidisciplinary team	2014
Professor Gareth Veal Julie Errington Sophie Rowbotham Nicola Illingworth Dr Ghada Malik et al.	Adaptive dosing approaches to the individualization of 13-cis-retinoic acid (isotretinoin) treatment for children with high-risk neuroblastoma	2013
Dr Sarra Ryan Dr Ed Schwalbe Mike Cole Yuan Lu Dr Meryl Lusher et al.	MYC family amplification and clinical risk-factors interact to predict an extremely poor prognosis in childhood medulloblastoma	2012
Dr Simon Bomken Dr Barry Davies Mike Cole Dr Katrina Wood Maritsa McDermott et al.	Percentage tumor necrosis following chemotherapy in neuroblastoma correlates with MYCN status but not survival	2011
Julie Errington Professor Alan Boddy Professor Gareth Veal Mike Cole	Pharmacokinetics of cyclophosphamide and its metabolites in pediatric patients receiving high-dose myeloablative therapy	2011
Julie Errington Professor Alan Boddy Professor Gareth Veal Mike Cole	Pharmacokinetics of high-dose cyclophosphamide and its metabolites in paediatric patients	2011
Tomasz Zaremba Huw Thomas Mike Cole Dr Sally Coulthard Professor Ruth Plummer et al.	Poly(ADP-ribose) polymerase-1 (PARP-1) pharmacogenetics, activity and expression analysis in cancer patients and healthy volunteers	2011
Dr Ed Schwalbe Dr Janet Lindsey Debbie Straughton Mike Cole Dr Hisham Megahed et al.	Rapid Diagnosis of Medulloblastoma Molecular Subgroups	2011
Dr Janet Lindsey Dr Rebecca Hill Dr Hisham Megahed Dr Meryl Lusher Dr Ed Schwalbe et al.	TP53 Mutations in Favorable-Risk Wnt/Wingless-Subtype Medulloblastomas	2011
Tomasz Zaremba Huw Thomas Mike Cole Professor Ruth Plummer Professor Nicola Curtin et al.	Doxorubicin-induced suppression of poly(ADP-ribose) polymerase-1 (PARP-1) activity and expression and its implication for PARP inhibitors in clinical trials	2010
Dr Joyce Nutt Kieran O'Toole Dr Fiona Black Mike Cole Professor Ruth Plummer et al.	Expression of methylthioadenosine phosphorylase (MTAP) in malignant pleural mesothelioma (MPM) and its implication for pemetrexed-based chemotherapy	2010
Professor Roderick Skinner Annie Parry Lisa Price Mike Cole Professor Andrew Pearson et al.	Glomerular Toxicity Persists 10 Years After Ifosfamide Treatment in Childhood and Is Not Predictable by Age or Dose	2010
Dr Jane Carr-Wilkinson Kieran O'Toole Angela Baker Julian Board Mike Cole et al.	High frequency of p53/MDM2/p14^ARFpathway abnormalities in relapsed neuroblastoma	2010
Julieann Sludden Melanie Griffin Mike Cole Dr Mark Verrill Dr David Jamieson et al.	Influence of pharmacogenetics on response and toxicity in breast cancer patients treated with doxorubicin and cyclophosphamide	2010
Mike Cole Professor Alan Boddy Professor Gareth Veal	Malnourished Malawian patients presenting with large Wilms tumours have a decreased vincristine clearance rate	2010
Professor Steven Clifford Dr Sarra Ryan Mike Cole Dr Meryl Lusher Kieran O'Toole et al.	MYC gene family amplification and expression in childhood medulloblastoma: Biological significance and utility for high-risk disease stratification	2010
Dr Malcolm Coulthard Mike Cole Professor Gareth Veal Dr Michael Keir	Human renal function maturation: a quantitative description using weight and postmenstrual age	2009
Professor Roderick Skinner Annie Parry Lisa Price Mike Cole Professor Andrew Pearson et al.	Persistent nephrotoxicity during 10-year follow-up after cisplatin or carboplatin treatment in childhood: Relevance of age and dose as risk factors	2009
Tomasz Zaremba Professor Ruth Plummer Dr Sally Coulthard Mike Cole Professor Nicola Curtin et al.	Poly(ADP-ribose) polymerase-1 polymorphisms, expression and activity in a panel of human tumor cell lines [abstract]	2009
Tomasz Zaremba Mike Cole Dr Sally Coulthard Professor Ruth Plummer Professor Nicola Curtin et al.	Poly(ADP-ribose) polymerase-1 polymorphisms, expression and activity in selected human tumour cell lines	2009
Mike Cole Professor Alan Boddy Dr Michael Keir Professor Gareth Veal	Estimation of renal function and its potential impact on carboplatin dosing in children with cancer	2008
Elizabeth Matheson Mike Cole Dr Bridget Wilkins Dr Andrew Hall	Mismatch repair defects in childhood acute lymphoblastic leukaemia at diagnosis and relapse	2008
Tomasz Zaremba Mike Cole Dr Sally Coulthard Professor Ruth Plummer Professor Nicola Curtin et al.	Poly(ADP-ribose) polymerase-1 (PARP-1) genomics in relation to activity in healthy volunteers and cancer patients	2008
Dr Patricia Turner Mike Cole Michael Batey Sandra Beare Professor Alan Boddy et al.	Reduced folate carrier single nucleotide polymorphism associated with methotrexate clearance in breast cancer patients	2008
Mike Cole Annie Parry Dr Michael Reid Professor Alan Boddy Professor Gareth Veal et al.	A study to determine the minimum volume of blood necessary to be discarded from a central venous catheter before a valid sample is obtained in children with cancer	2007
Dr Michael Keir Mike Cole Annie Parry Professor Alan Boddy Professor Gareth Veal et al.	Estimating glomerular filtration rate in children with cancer - Impact of methodology on carboplatin dosing	2007
Dr Lindi Chen Professor Archibald Malcolm Dr Katrina Wood Mike Cole Professor Andrew Pearson et al.	p53 is nuclear and functional in both undifferentiated and differentiated neuroblastoma	2007
Dr Jo Lee Dr Mark Verrill Julieann Sludden Melanie Griffin Sharon Erb et al.	Pharmacogenetic influences on outcome from AC chemotherapy in the treatment of breast cancer	2007
Professor Gareth Veal Mike Cole Geoffrey Taylor Julie Errington Professor Alan Boddy et al.	Pharmacogenetics and metabolism of cyclophosphamide in paediatric cancer patients	2007
Professor Gareth Veal Mike Cole Julie Errington Professor Alan Boddy	Pharmacokinetics and metabolism of 13-cis-retinoic acid (isotretinoin) in children with high-risk neuroblastoma - A study of the United Kingdom Children's Cancer Study Group	2007
Daniel Routledge Dr David Bourn Dr Nicholas Bown Mike Cole Professor Andrew Gennery et al.	Quantitative assessment of mixed chimerism in allogeneic stem cell transplant patients - A comparison of molecular genetic and cytogenetic approaches	2007
Dr Debbie Scott Debbie Straughton Mike Cole Professor Simon Bailey Professor David Ellison et al.	Identification and analysis of tumor suppressor loci at chromosome 10q23.3-10q25.3 in medulloblastoma	2006
Mike Cole Professor Alan Boddy Dr Pamela Kearns Lisa Price Annie Parry et al.	Potential clinical impact of taking multiple blood samples for research studies in paediatric oncology: How much do we really know?	2006
Professor Gareth Veal Mike Cole Julie Errington Annie Parry Dr Juliet Hale et al.	Pharmacokinetics of dactinomycin in a pediatric patient population: A United Kingdom Children's Cancer Study Group study	2005
Mike Cole Annie Parry Dr Michael Keir Professor Andrew Pearson Professor Alan Boddy et al.	Estimation of glomerular filtration rate in paediatric cancer patients using ⁵¹CR-EDTA population pharmacokinetics	2004
Charles McManamy Dr Jayne Lamont Mike Cole Professor Andrew Pearson Professor Steven Clifford et al.	Morphophenotypic variation predicts clinical behavior in childhood non-desmoplastic medulloblastomas	2003
Huw Thomas Mike Cole Suzanne Elliott Professor Herbie Newell Professor Alan Calvert et al.	Randomized cross-over clinical trial to study potential pharmacokinetic interactions between cisplatin or carboplatin and etoposide	2002
Alice Burns Dr Evelyn Jaros Mike Cole Emeritus Professor Robert Perry Professor Andrew Pearson et al.	The molecular pathology of p53 in primitive neuroectodermal tumours of the central nervous system	2002
Diana Levett Dr Peter Middleton Mike Cole Dr Michael Reid	A demographic study of the clinical significance of minimal residual disease in children with acute lymphoblastic leukemia	2001
Gavin Cuthbert Dr Nicholas Bown Mike Cole	Comparison of three BCR/ABL FISH probe systems for quantitative interphase analysis	2001
Mike Cole Professor Andrew Pearson Professor Alan Boddy	Cyclophosphamide metabolism in children following a 1-h and a 24-h infusion	2001
Professor Deborah Tweddle Mike Cole Professor Andrew Pearson	OPEC/OJEC for stage 4 neuroblastoma in children over 1 year of age	2001
Professor Deborah Tweddle Professor Archibald Malcolm Mike Cole Professor Andrew Pearson Professor John Lunec et al.	p53 cellular localization and function in neuroblastoma: evidence for defective G1 arrest despite WAF1 induction in MYCN-amplified cells	2001
Mike Cole Professor Andrew Pearson Professor Alan Boddy	Cyclophosphamide metabolism in children with Fanconi's anaemia	1999
Mike Cole Emerita Professor Suzanne Cholerton Professor Ann Daly Professor Andrew Pearson Professor Alan Boddy et al.	The effect of fluconazole on cyclophosphamide metabolism in children	1999
Professor Andrew Pearson Professor Herbie Newell Mike Cole	A study of the feasibility and accuracy of pharmacokinetically guided etoposide dosing in children	1998
Mike Cole Professor Andrew Pearson Professor Alan Boddy	Cyclophosphamide metabolism in children with Fanconi's anaemia	1998
Professor Louise Parker Mike Cole Emeritus Professor Alan Craft	Neonatal vitamin K administration and childhood cancer in the north of England: Retrospective case-control study	1998
Professor Deborah Tweddle Professor Archibald Malcolm Dr Michael Reid Mike Cole Professor John Lunec et al.	TP53 and related protein expression in primary and metastatic neuroblastoma	1998
Professor Alan Boddy Mike Cole Professor Andrew Pearson	Cyclophosphamide pharmacokinetics in children	1996
Professor Roderick Skinner Mike Cole Professor Andrew Pearson Dr Malcolm Coulthard Emeritus Professor Alan Craft et al.	Specificity of pH and osmolality of early morning urine sample in assessing distal renal tubular function in children: Results in healthy children	1996
Professor Alan Boddy Mike Cole Professor Andrew Pearson Professor Herbie Newell	Comparison of methods for the estimation of carboplatin pharmacokinetics in paediatric cancer patients	1995
Professor Alan Boddy Mike Cole Professor Andrew Pearson	Cyclophosphamide Metabolism in Children	1995
Emeritus Professor Alan Craft Mike Cole	Screening for wilms' tumor in patients with aniridia, Beckwith syndrome, or hemihypertrophy	1995
Professor Alan Boddy Mike Cole Professor Andrew Pearson	The kinetics of the auto-induction of ifosfamide metabolism during continuous infusion	1995
Mike Cole Emeritus Professor Alan Craft Professor Louise Parker	Urinary creatinine adjusted reference ranges for homovanillic and vanillylmandelic acid in children and adults	1995
Dr Andrew Hall Professor Archibald Malcolm Mike Cole Dr Jennifer Kernahan Dr Michael Reid et al.	Expression of mu class glutathione S-transferase correlates with event-free survival in childhood acute lymphoblastic leukemia	1994
Professor Louise Parker Emeritus Professor Alan Craft Mike Cole James Smith	False positive results in a neuroblastoma screening programme	1994
Professor Roderick Skinner Mike Cole Professor Andrew Pearson Dr Michael Keir Dr Malcolm Coulthard et al.	Inaccuracy of glomerular-filtration rate estimation from height/plasma creatinine ratio	1994
Professor Louise Parker Mike Cole Emeritus Professor Alan Craft	Screening infants for neuroblastoma: the parents' perspective	1994
Mike Cole Emeritus Professor Alan Craft	Screening infants for neuroblastoma: the parents perspective in false-positive cases	1994
Mike Cole Emeritus Professor Alan Craft	Creatinine related reference ranges for urinary homovanillic-acid and vanillylmandelic acid at 6 months of age	1993
Professor Andrew Pearson Professor Herbie Newell Mike Cole	Etoposide pharmacokinetics in children: the development and prospective validation of a dosing equation	1993
Emeritus Professor Alan Craft Professor Louise Parker Mike Cole Julian Smith	A pilot study of screening for neuroblastoma in the north of England	1992
Professor Louise Parker Emeritus Professor Alan Craft Mike Cole Julian Smith	Screening for neuroblastoma in the north of England	1992
Emeritus Professor Alan Craft Professor Louise Parker Mike Cole Julian Smith	Screening for neuroblastoma in the northern region of England: laboratory aspects	1992