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Browsing publications by Mike Cole.

Newcastle AuthorsTitleYearFull text
Dr Timothy Cheetham
Mike Cole
Dr Mario Abinun
Dr Sonya Carnell
Jon Prichard
et al.
Adjuvant Rituximab-Exploratory Trial in Young People With Graves Disease2022
Dr Arthur Pratt
Dr Stefan Siebert
Mike Cole
Dr Deborah Stocken
Amy Cranston
et al.
Targeting synovial fibroblast proliferation in rheumatoid arthritis (TRAFIC): an open-label, dose-finding, phase 1b trial2021
Mike Cole
Professor Fai Ng
Dr Stefan Siebert
Dr Arthur Pratt
Professor John Isaacs
et al.
TRAFIC: statistical design and analysis plan for a pragmatic early phase 1/2 Bayesian adaptive dose escalation trial in rheumatoid arthritis2021
Dr Claire Wood
Mike Cole
Ruth Wood
Professor John Matthews
Professor Simon Pearce
et al.
Randomised trial of block and replace vs dose titration thionamide in young people with thyrotoxicosis2020
Dr Stefan Siebert
Dr Arthur Pratt
Dr Deborah Stocken
Dr Miranda Morton
Amy Cranston
et al.
Targeting the rheumatoid arthritis synovial fibroblast via cyclin dependent kinase inhibition: An early phase trial2020
Mike Cole
Dr Ann Marie Hynes
Denise Howel
Dr Lesley Hall
Dr Mario Abinun
et al.
Adjuvant rituximab, a potential treatment for the young patient with Graves’ hyperthyroidism (RiGD): study protocol for a single-arm, single-stage, phase II trial2019
Professor Jeremy Parr
Dr Emma Todhunter
Dr Lindsay Pennington
Dr Deborah Stocken
Dr Jill Cadwgan
et al.
Drooling Reduction Intervention randomised trial (DRI): comparing the efficacy and acceptability of hyoscine patches and glycopyrronium liquid on drooling in children with neurodisability2018
Professor Vinidh Paleri
Dr Joanne Patterson
Dr Deborah Stocken
Mike Cole
Professor Luke Vale
et al.
A feasibility study incorporating a pilot randomised controlled trial of oral feeding plus pre-treatment gastrostomy tube versus oral feeding plus as-needed nasogastric tube feeding in patients undergoing chemoradiation for head and neck cancer (TUBE trial): study protocol2016
Dr Sarah Fordham
Mike Cole
Professor Julie Irving
Professor James Allan
Cytarabine preferentially induces mutation at specific sequences in the genome which are identifiable in relapsed acute myeloid leukaemia2015
Dr Ashleigh Herriott
Dr Susan Tudhope
Gesa Junge
Natalie Rodrigues
Dr Miranda Morton
et al.
PARP1 expression, activity and ex vivo sensitivity to the PARP inhibitor, talazoparib (BMN 673), in Chronic Lymphocytic Leukaemia2015
Dr Sarah Fordham
Mike Cole
Professor Julie Irving
Professor James Allan
Cytarabine leaves a mutational fingerprint in relapsing leukemia2014
Dr Jess Dyson
Dr Dipanker Chattopadhyay
Rajiv Lochan Jayadeva
Dr Imran Patanwala
Mike Cole
et al.
Hepatocellular cancer: The impact of obesity, type 2 diabetes and a multidisciplinary team2014
Professor Gareth Veal
Julie Errington
Sophie Rowbotham
Nicola Illingworth
Dr Ghada Malik
et al.
Adaptive dosing approaches to the individualization of 13-cis-retinoic acid (isotretinoin) treatment for children with high-risk neuroblastoma2013
Dr Sarra Ryan
Dr Ed Schwalbe
Mike Cole
Yuan Lu
Dr Meryl Lusher
et al.
MYC family amplification and clinical risk-factors interact to predict an extremely poor prognosis in childhood medulloblastoma2012
Dr Simon Bomken
Dr Barry Davies
Mike Cole
Dr Katrina Wood
Maritsa McDermott
et al.
Percentage tumor necrosis following chemotherapy in neuroblastoma correlates with MYCN status but not survival2011
Julie Errington
Professor Alan Boddy
Professor Gareth Veal
Mike Cole
Pharmacokinetics of cyclophosphamide and its metabolites in pediatric patients receiving high-dose myeloablative therapy2011
Julie Errington
Professor Alan Boddy
Professor Gareth Veal
Mike Cole
Pharmacokinetics of high-dose cyclophosphamide and its metabolites in paediatric patients2011
Tomasz Zaremba
Huw Thomas
Mike Cole
Dr Sally Coulthard
Professor Ruth Plummer
et al.
Poly(ADP-ribose) polymerase-1 (PARP-1) pharmacogenetics, activity and expression analysis in cancer patients and healthy volunteers2011
Dr Ed Schwalbe
Dr Janet Lindsey
Debbie Straughton
Mike Cole
Dr Hisham Megahed
et al.
Rapid Diagnosis of Medulloblastoma Molecular Subgroups2011
Dr Janet Lindsey
Dr Rebecca Hill
Dr Hisham Megahed
Dr Meryl Lusher
Dr Ed Schwalbe
et al.
TP53 Mutations in Favorable-Risk Wnt/Wingless-Subtype Medulloblastomas2011
Tomasz Zaremba
Huw Thomas
Mike Cole
Professor Ruth Plummer
Professor Nicola Curtin
et al.
Doxorubicin-induced suppression of poly(ADP-ribose) polymerase-1 (PARP-1) activity and expression and its implication for PARP inhibitors in clinical trials2010
Dr Joyce Nutt
Kieran O'Toole
Dr Fiona Black
Mike Cole
Professor Ruth Plummer
et al.
Expression of methylthioadenosine phosphorylase (MTAP) in malignant pleural mesothelioma (MPM) and its implication for pemetrexed-based chemotherapy2010
Professor Roderick Skinner
Annie Parry
Lisa Price
Mike Cole
Professor Andrew Pearson
et al.
Glomerular Toxicity Persists 10 Years After Ifosfamide Treatment in Childhood and Is Not Predictable by Age or Dose2010
Dr Jane Carr-Wilkinson
Kieran O'Toole
Angela Baker
Julian Board
Mike Cole
et al.
High frequency of p53/MDM2/p14ARF pathway abnormalities in relapsed neuroblastoma2010
Julieann Sludden
Melanie Griffin
Mike Cole
Dr Mark Verrill
Dr David Jamieson
et al.
Influence of pharmacogenetics on response and toxicity in breast cancer patients treated with doxorubicin and cyclophosphamide2010
Mike Cole
Professor Alan Boddy
Professor Gareth Veal
Malnourished Malawian patients presenting with large Wilms tumours have a decreased vincristine clearance rate2010
Professor Steven Clifford
Dr Sarra Ryan
Mike Cole
Dr Meryl Lusher
Kieran O'Toole
et al.
MYC gene family amplification and expression in childhood medulloblastoma: Biological significance and utility for high-risk disease stratification2010
Dr Malcolm Coulthard
Dr Bridget Wilkins
Mike Cole
Professor Gareth Veal
Dr Michael Keir
et al.
Human renal function maturation: a quantitative description using weight and postmenstrual age2009
Professor Roderick Skinner
Annie Parry
Lisa Price
Mike Cole
Professor Andrew Pearson
et al.
Persistent nephrotoxicity during 10-year follow-up after cisplatin or carboplatin treatment in childhood: Relevance of age and dose as risk factors2009
Tomasz Zaremba
Professor Ruth Plummer
Dr Sally Coulthard
Mike Cole
Professor Nicola Curtin
et al.
Poly(ADP-ribose) polymerase-1 polymorphisms, expression and activity in a panel of human tumor cell lines [abstract]2009
Tomasz Zaremba
Mike Cole
Dr Sally Coulthard
Professor Ruth Plummer
Professor Nicola Curtin
et al.
Poly(ADP-ribose) polymerase-1 polymorphisms, expression and activity in selected human tumour cell lines2009
Mike Cole
Professor Alan Boddy
Dr Michael Keir
Professor Gareth Veal
Estimation of renal function and its potential impact on carboplatin dosing in children with cancer2008
Elizabeth Matheson
Mike Cole
Dr Bridget Wilkins
Dr Andrew Hall
Mismatch repair defects in childhood acute lymphoblastic leukaemia at diagnosis and relapse2008
Tomasz Zaremba
Mike Cole
Dr Sally Coulthard
Professor Ruth Plummer
Professor Nicola Curtin
et al.
Poly(ADP-ribose) polymerase-1 (PARP-1) genomics in relation to activity in healthy volunteers and cancer patients2008
Dr Patricia Turner
Mike Cole
Michael Batey
Sandra Beare
Professor Alan Boddy
et al.
Reduced folate carrier single nucleotide polymorphism associated with methotrexate clearance in breast cancer patients2008
Mike Cole
Annie Parry
Dr Michael Reid
Professor Alan Boddy
Professor Gareth Veal
et al.
A study to determine the minimum volume of blood necessary to be discarded from a central venous catheter before a valid sample is obtained in children with cancer2007
Dr Michael Keir
Mike Cole
Annie Parry
Professor Alan Boddy
Professor Gareth Veal
et al.
Estimating glomerular filtration rate in children with cancer - Impact of methodology on carboplatin dosing2007
Dr Lindi Chen
Professor Archibald Malcolm
Dr Katrina Wood
Mike Cole
Professor Andrew Pearson
et al.
p53 is nuclear and functional in both undifferentiated and differentiated neuroblastoma2007
Dr Jo Lee
Dr Mark Verrill
Julieann Sludden
Melanie Griffin
Sharon Erb
et al.
Pharmacogenetic influences on outcome from AC chemotherapy in the treatment of breast cancer2007
Professor Gareth Veal
Mike Cole
Geoffrey Taylor
Julie Errington
Professor Alan Boddy
et al.
Pharmacogenetics and metabolism of cyclophosphamide in paediatric cancer patients2007
Professor Gareth Veal
Mike Cole
Julie Errington
Professor Alan Boddy
Pharmacokinetics and metabolism of 13-cis-retinoic acid (isotretinoin) in children with high-risk neuroblastoma - A study of the United Kingdom Children's Cancer Study Group2007
Daniel Routledge
Dr David Bourn
Dr Nicholas Bown
Mike Cole
Professor Andrew Gennery
et al.
Quantitative assessment of mixed chimerism in allogeneic stem cell transplant patients - A comparison of molecular genetic and cytogenetic approaches2007
Dr Debbie Scott
Debbie Straughton
Mike Cole
Professor Simon Bailey
Professor David Ellison
et al.
Identification and analysis of tumor suppressor loci at chromosome 10q23.3-10q25.3 in medulloblastoma2006
Mike Cole
Professor Alan Boddy
Dr Pamela Kearns
Lisa Price
Annie Parry
et al.
Potential clinical impact of taking multiple blood samples for research studies in paediatric oncology: How much do we really know?2006
Professor Gareth Veal
Mike Cole
Julie Errington
Annie Parry
Dr Juliet Hale
et al.
Pharmacokinetics of dactinomycin in a pediatric patient population: A United Kingdom Children's Cancer Study Group study2005
Mike Cole
Annie Parry
Dr Michael Keir
Professor Andrew Pearson
Professor Alan Boddy
et al.
Estimation of glomerular filtration rate in paediatric cancer patients using 51CR-EDTA population pharmacokinetics2004
Charles McManamy
Dr Jayne Lamont
Mike Cole
Professor Andrew Pearson
Professor Steven Clifford
et al.
Morphophenotypic variation predicts clinical behavior in childhood non-desmoplastic medulloblastomas2003
Huw Thomas
Mike Cole
Suzanne Elliott
Professor Herbie Newell
Professor Alan Calvert
et al.
Randomized cross-over clinical trial to study potential pharmacokinetic interactions between cisplatin or carboplatin and etoposide2002
Alice Burns
Dr Evelyn Jaros
Mike Cole
Emeritus Professor Robert Perry
Professor Andrew Pearson
et al.
The molecular pathology of p53 in primitive neuroectodermal tumours of the central nervous system2002
Diana Levett
Dr Peter Middleton
Mike Cole
Dr Michael Reid
A demographic study of the clinical significance of minimal residual disease in children with acute lymphoblastic leukemia2001
Gavin Cuthbert
Dr Nicholas Bown
Mike Cole
Comparison of three BCR/ABL FISH probe systems for quantitative interphase analysis2001
Mike Cole
Professor Andrew Pearson
Professor Alan Boddy
Cyclophosphamide metabolism in children following a 1-h and a 24-h infusion2001
Professor Deborah Tweddle
Mike Cole
Professor Andrew Pearson
OPEC/OJEC for stage 4 neuroblastoma in children over 1 year of age2001
Professor Deborah Tweddle
Professor Archibald Malcolm
Mike Cole
Professor Andrew Pearson
Professor John Lunec
et al.
p53 cellular localization and function in neuroblastoma: evidence for defective G1 arrest despite WAF1 induction in MYCN-amplified cells2001
Mike Cole
Professor Andrew Pearson
Professor Alan Boddy
Cyclophosphamide metabolism in children with Fanconi's anaemia1999
Mike Cole
Emerita Professor Suzanne Cholerton
Professor Ann Daly
Professor Andrew Pearson
Professor Alan Boddy
et al.
The effect of fluconazole on cyclophosphamide metabolism in children1999
Professor Andrew Pearson
Professor Herbie Newell
Mike Cole
A study of the feasibility and accuracy of pharmacokinetically guided etoposide dosing in children1998
Mike Cole
Professor Andrew Pearson
Professor Alan Boddy
Cyclophosphamide metabolism in children with Fanconi's anaemia1998
Professor Louise Parker
Mike Cole
Emeritus Professor Alan Craft
Neonatal vitamin K administration and childhood cancer in the north of England: Retrospective case-control study1998
Professor Deborah Tweddle
Professor Archibald Malcolm
Dr Michael Reid
Mike Cole
Professor John Lunec
et al.
TP53 and related protein expression in primary and metastatic neuroblastoma1998
Professor Alan Boddy
Mike Cole
Professor Andrew Pearson
Cyclophosphamide pharmacokinetics in children1996
Professor Roderick Skinner
Mike Cole
Professor Andrew Pearson
Dr Malcolm Coulthard
Emeritus Professor Alan Craft
et al.
Specificity of pH and osmolality of early morning urine sample in assessing distal renal tubular function in children: Results in healthy children1996
Professor Alan Boddy
Mike Cole
Professor Andrew Pearson
Professor Herbie Newell
Comparison of methods for the estimation of carboplatin pharmacokinetics in paediatric cancer patients
1995
Professor Alan Boddy
Mike Cole
Professor Andrew Pearson
Cyclophosphamide Metabolism in Children1995
Emeritus Professor Alan Craft
Mike Cole
Screening for wilms' tumor in patients with aniridia, Beckwith syndrome, or hemihypertrophy1995
Professor Alan Boddy
Mike Cole
Professor Andrew Pearson
The kinetics of the auto-induction of ifosfamide metabolism during continuous infusion1995
Mike Cole
Emeritus Professor Alan Craft
Professor Louise Parker
Urinary creatinine adjusted reference ranges for homovanillic and vanillylmandelic acid in children and adults1995
Dr Andrew Hall
Professor Archibald Malcolm
Mike Cole
Dr Jennifer Kernahan
Dr Michael Reid
et al.
Expression of mu class glutathione S-transferase correlates with event-free survival in childhood acute lymphoblastic leukemia1994
Professor Louise Parker
Emeritus Professor Alan Craft
Mike Cole
James Smith
False positive results in a neuroblastoma screening programme1994
Professor Roderick Skinner
Mike Cole
Professor Andrew Pearson
Dr Michael Keir
Dr Malcolm Coulthard
et al.
Inaccuracy of glomerular-filtration rate estimation from height/plasma creatinine ratio1994
Professor Louise Parker
Mike Cole
Emeritus Professor Alan Craft
Screening infants for neuroblastoma: the parents' perspective1994
Mike Cole
Emeritus Professor Alan Craft
Screening infants for neuroblastoma: the parents perspective in false-positive cases1994
Mike Cole
Emeritus Professor Alan Craft
Creatinine related reference ranges for urinary homovanillic-acid and vanillylmandelic acid at 6 months of age1993
Professor Andrew Pearson
Professor Herbie Newell
Mike Cole
Etoposide pharmacokinetics in children: the development and prospective validation of a dosing equation1993
Emeritus Professor Alan Craft
Professor Louise Parker
Mike Cole
Julian Smith
A pilot study of screening for neuroblastoma in the north of England1992
Professor Louise Parker
Emeritus Professor Alan Craft
Mike Cole
Julian Smith
Screening for neuroblastoma in the north of England1992
Emeritus Professor Alan Craft
Professor Louise Parker
Mike Cole
Julian Smith
Screening for neuroblastoma in the northern region of England: laboratory aspects1992